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sangerinstitute.bsky.social
Wellcome Sanger Institute
@sangerinstitute.bsky.social
3.3K followers 94 following 200 posts
We are a world leader in genomics research. We apply and explore genomic technologies to advance the understanding of biology and improve health 🧬
https://www.sanger.ac.uk/
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Reposted by Wellcome Sanger Institute
camvetschool.bsky.social
A big congratulations🎉to Catherine Wilson, our Senior Clinical Training Scholar in Veterinary Pathology, on the publication of her final PhD paper in @nature.com working with @sangerinstitute.bsky.social and from her time at the @liverpooluni.bsky.social 👇🏽
livuniresearch.bsky.social Research@LivUni @livuniresearch.bsky.social · 1d
🧬🦠New research published in @nature.com reveals how Salmonella moves between humans, animals and household environments in Malawi, reinforcing the importance of a #OneHealth approach in reducing the spread of bacteria🌍🔬

Read our blog to find out more 👉 www.liverpool.ac.uk/research/new...
November 13, 2025 at 12:44 PM
sangerinstitute.bsky.social
A new type of cancer cell has been discovered in childhood leukaemia, which could impact clinical care for children with T-cell leukaemia (T-ALL).

Read more about this discovery and how it could help children with blood cancer, here ⤵️

www.sanger.ac.uk/news_item/my...
Mystery of treatment-resistant childhood leukaemia uncovered
Discovery of a new cancer cell type could enable testing to predict treatment-resistant blood cancer in children with a certain type of leukaemia. This could allow them to reduce treatment intensity f...
www.sanger.ac.uk
November 12, 2025 at 10:37 AM
sangerinstitute.bsky.social
Latin America’s genetic diversity is underrepresented in research 🌍

We spoke with Patricia Possik about boosting research equity, building capacity and her acral melanoma work.

https://sangerinstitute.blog/2025/11/11/five-questions-on-genomics-in-latin-america-with-dr-patricia-abrao-possik/
Five questions on genomics in Latin America with Dr Patricia Abrão Possik - Wellcome Sanger Institute Blog
Despite its extraordinary genetic diversity, Latin America remains largely absent from global genomic studies. Dr Patricia Abrão Possik discusses efforts to boost regional research capacity and insights from her work on acral melanoma.
sangerinstitute.blog
November 11, 2025 at 1:25 PM
sangerinstitute.bsky.social
Huge congratulations to our Senior Group Leader, Dr David Adams who has won an award for his research on melanoma. 🎉

The award for Outstanding Research was presented at the Society for Melanoma Research (SMR) 22nd International Congress in Amsterdam.
David sits with his award certificate and on the left of his picture, his quote reads: "I’m honoured to have received the Outstanding Research Award. Melanoma remains one of the deadliest forms of cancer, and there’s still much more to do to improve treatment options. Improving our understanding of this disease at the molecular level is essential if we’re to find better ways to prevent and treat it."
November 10, 2025 at 10:59 AM
sangerinstitute.bsky.social
Bowel cancer cases in people under 50 are rising worldwide, and the reasons remain unclear.

With a new @erc.europa.eu Synergy Grant, scientists will look into how gut bacteria in early life might increase the risk of bowel cancer in young adults. 👇

www.sanger.ac.uk/news_item/sa...
Sanger scientists receive major grant to study rise of early onset colorectal cancer
Dr Trevor Lawley and Professor Mike Stratton awarded funding to enable investigation into the roots of growing cancer concern.
www.sanger.ac.uk
November 6, 2025 at 3:16 PM
sangerinstitute.bsky.social
E. coli can spread as quickly as swine flu, new research reveals. 🦠

For the first time, scientists can predict the rate at which gut bacteria pass between people — a major step towards tackling antibiotic-resistant infections.

Read here ⤵️
sanger.ac.uk/news_item/ad...
Advanced disease modelling shows some gut bacteria can spread as rapidly as viruses
Experts can now predict the transmission rate of a bacterial E. coli infection in the same way as they can for viral pandemics, which can help battling treatment-resistant infections in the future.
sanger.ac.uk
November 4, 2025 at 11:55 AM
sangerinstitute.bsky.social
145 families finally get answers about rare conditions that had gone undiagnosed for years. 🧬

By looking more closely at how DNA can rearrange itself, researchers uncovered changes that standard tests often miss.

Find out more 👇
sanger.ac.uk/news_item/14...
145 families receive a diagnosis with new genomic method
Experts have developed a new method for identifying structural changes in DNA, providing insights for 145 families and highlighting the importance of incorporating these changes into clinical practice...
sanger.ac.uk
November 3, 2025 at 11:05 AM
sangerinstitute.bsky.social
Haemophilus influenzae bacteria can cause up to 200 million childhood infections every year, and new research is helping pave the way for a future vaccine against this. 🔬

Find out more⤵️
www.sanger.ac.uk/news_item/op...
Opening the door to a vaccine for multiple childhood infections
The first large-scale genomic exploration of H. influenzae has revealed extensive antibiotic resistance and uncovered genetic clues that could help in future vaccine development.
www.sanger.ac.uk
October 31, 2025 at 10:55 AM
sangerinstitute.bsky.social
At first, Ronnie Crawford was hesitant about coding, but now he helps researchers tackle complex challenges with AI 💻

Read about his career & the advice he would give his younger self ⤵️
https://sangerinstitute.blog/2025/10/29/ai-and-genomics-pave-the-way-to-new-data-driven-scientific-discoveries/
AI and genomics pave the way to new data-driven scientific discoveries - Wellcome Sanger Institute Blog
Artificial intelligence (AI) is reshaping how we analyse biological data – from predicting protein structures to uncovering insights from vast genomic datasets. Ronnie Crawford, Science Solutions Lead at the Wellcome Sanger Institute, bridg...
sangerinstitute.blog
October 29, 2025 at 10:44 AM
sangerinstitute.bsky.social
Congratulations to Roser Vento-Tormo, who has been awarded the 2025 Foulkes Foundation Academy of Medical Sciences Medal! 🎉

This award acknowledges her transformative work that has opened pathways for future diagnostics and treatments in women’s health. 🧬

Find out more ⤵️
acmedsci.bsky.social Academy of Medical Sciences @acmedsci.bsky.social · 16d
Congratulations to Dr Roser Vento-Tormo, winner of the 2025 Foulkes Foundation Academy of Medical Sciences Medal 🌟

Her pioneering work is transforming our understanding of the female reproductive system and advancing women’s health research.

Read more: bit.ly/47ufNz2

@sangerinstitute.bsky.social
Dr Roser Vento-Tormo, recipient of the Foulkes Foundation Academy of Medical Sciences Medal, next to a quote that reads: "I am deeply honoured to receive the Foulkes Foundation Medal. Women’s health has too often been overlooked in biomedical science, and I am proud that our discoveries are beginning to change this."
October 28, 2025 at 1:58 PM
sangerinstitute.bsky.social
The so-called 'London Underground mosquito' linked to West Nile Virus evolved over 1,000 years ago — not 200 years ago in Europe. 🦟

New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
October 24, 2025 at 9:04 AM
Reposted by Wellcome Sanger Institute
amjadkhalaf.bsky.social
Really, really happy that our work on microsporidian genomes is now out in @plosbiology.org! A huge thank you to my coauthors, my supervisors @mblaxter.bsky.social & @marakat.bsky.social, the editors @roliroberts.bsky.social & Joseph Heitman, and the reviewers ❤️ plos.io/48HsAQJ
October 22, 2025 at 10:47 AM
sangerinstitute.bsky.social
A new dimension of genomics is here. Spatial transcriptomics is transforming how we understand tissues – revealing where genes act, and why it matters. 🧬

Try our spatial-inspired game before reading the latest blog ⬇️ https://sangerinstitute.blog/2025/10/22/what-is-spatial-transcriptomics/
October 22, 2025 at 1:02 PM
sangerinstitute.bsky.social
An amazing achievement - congratulations to all involved! 👏
joanameier.bsky.social Joana Meier @joanameier.bsky.social · 29d
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
October 16, 2025 at 9:15 AM
Reposted by Wellcome Sanger Institute
joanameier.bsky.social
Celebrating the first 1000 genomes of Lepidoptera in Europe, sequenced at @sangerinstitute.bsky.social in collaboration with sampling hubs across the UK via the DToL project www.darwintreeoflife.org & across Europe via
@projectpsyche.bsky.social www.projectpsyche.org &
@10klepgenomes.bsky.social
October 15, 2025 at 9:17 PM
sangerinstitute.bsky.social
Can AI reveal how genes are switched on and off by only looking at the DNA sequence? Jussi Taipale’s group blends lab work with predictive models to try and provide an answer 🧬

http://bit.ly/3KSYHTF
“I’m not trying to do science just for scientists. I’m doing it to try to solve important problems that will make a difference”: Jussi Taipale on genomics at scale and...
Professor Jussi Taipale joined the Wellcome Sanger Institute in January this year as a Senior Group Leader in the Generative and Synthetic Genomics Programme. His ambition? To predict gene expression directly from DNA sequence. In this blog, he reflects on his international research journey, how biology is scaling up, and why his research group aims to solve one of the biggest puzzles in genomics.
bit.ly
October 16, 2025 at 8:09 AM
Reposted by Wellcome Sanger Institute
f1000publishing.bsky.social
In 2021, Wellcome Open Research launched the Tree of Life Gateway with the goal to publish the genome sequences of every species.

In 2024, the Gateway published the 1,000th Genome Note.

Explore this milestone with our recent blog post 🔗spr.ly/6009AxyLP

@sangerinstitute.bsky.social
The Sanger Institute established the Tree of Life program to support the Earth BioGenome Project, sequencing all of Earth's eukaryotic biodiversity. Portrait of Professor Mark Blaxter included. Wellcome Sanger Institute logo.
October 14, 2025 at 6:00 PM
Reposted by Wellcome Sanger Institute
ebpgenome.bsky.social
EBP R&D experts are paving the way for new discoveries, one extraction at a time.
@ergabiodiv.bsky.social @vertebrategenomes.bsky.social egenomes.bsky.social @kurakulabmsm.bsky.social @atlasea.bsky.social @biogeneurope.bsky.social @sangerinstitute.bsky.social @invertebrates.bsky.social
October 14, 2025 at 9:09 PM
sangerinstitute.bsky.social
Hidden genetic changes have been uncovered in healthy cells, thanks to an improved version of NanoSeq, an ultra-accurate DNA sequencing tool. 🧬

The breakthrough offers new insights into ageing, disease, and the origins of cancer. ⤵️

www.sanger.ac.uk/news_item/im...
Improved genetic tool reveals hidden mutations that can drive cancer
A new and improved version of NanoSeq unlocks clues into ageing, disease and cancer development.
www.sanger.ac.uk
October 9, 2025 at 10:02 AM
sangerinstitute.bsky.social
A hidden evolutionary process has been uncovered in sperm — where certain harmful DNA changes are naturally favoured as men age.

This gives some changes a competitive edge and increases the risk of genetic conditions. 🔬

Read here 👇
www.sanger.ac.uk/news_item/hi...
Hidden evolution in sperm raises disease risk for children as men age
Researchers reveal how certain harmful DNA variations become more common in sperm as men age, raising genetic disease risk for offspring.
www.sanger.ac.uk
October 8, 2025 at 3:36 PM
sangerinstitute.bsky.social
Lupus is a complex autoimmune condition that affects thousands of people globally 🌍

This #LupusAwarenessMonth, learn how our scientists are advancing understanding through genetics and immune research 🧬

https://sangerinstitute.blog/2025/10/07/five-questions-on-lupus-with-catherine-sutherland/
Catherine Sutherland at her desk working.
October 7, 2025 at 11:58 AM
sangerinstitute.bsky.social
PhD Applications now open! Join a world-class community training the next generation of genome scientists and clinicians.

Apply now 👉 lnkd.in/g_JfNuFE

📅 Closes 27 Nov 2025
#ScienceCareers
October 6, 2025 at 1:03 PM
sangerinstitute.bsky.social
This role, based at Sanger, will lead on the communications for the Atlas of Variant Effects Alliance - an initiative that is mapping the effects of all the possible variants of human genes 🧬

This is a part-time role, closing on 14th Oct.
More info ⤵️
sanger.wd103.myworkdayjobs.com/WellcomeSang...
October 2, 2025 at 10:25 AM
sangerinstitute.bsky.social
Antimicrobial resistance is a major global health threat 🌍

Without action, deaths will keep rising.

See how we’re tackling it in our new blog ⬇️

https://sangerinstitute.blog/2025/10/01/ten-ways-the-sanger-institute-is-tackling-the-global-fight-against-amr/
Different infectious agents.
October 1, 2025 at 9:58 AM
sangerinstitute.bsky.social
Clinical academics are a bridge between patient care and research – ensuring discoveries translate into treatments and guiding innovation 🔎

The @acmedsci.bsky.social and other UK leaders, including the Sanger Institute, are committed to addressing the decline in these positions. Read how ⤵️
acmedsci.bsky.social Academy of Medical Sciences @acmedsci.bsky.social · Sep 30
Today we’re proud to share our Clinical Academics Summit statement, signed by 40+ organisations 🤝

⚠️ Clinical academics are declining
✅ Our summit committed to action to help reverse this trend

👉 Read the full statement: bit.ly/3Ktb5JQ

Quote @rosalindsmyth.bsky.social
A quote card featuring Professor Rosalind Smyth CBC FMedSci, saying "The decline in clinical academic numbers represents a genuine threat to patient care and the UK's research leadership. This statement shows that if we act with urgency and a shared commitment, we can reverse this trend. "
September 30, 2025 at 3:20 PM