Rebecca Hull-Meichle
@rlhull-meichle.bsky.social
CERC in the Islet Microenvironment and knowledge-seeker at the University of Alberta
https://sites.google.com/ualberta.ca/islet-microenvironment/home
https://sites.google.com/ualberta.ca/islet-microenvironment/home
Reposted by Rebecca Hull-Meichle
Our new paper is out now in Nature Communications! We uncovered the function of XBP1 in beta cells of a preclinical model of T1D and identified unique and shared gene regulatory networks driven by IRE1 and XBP1.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in non-obese diabetic mice - Nature Communications
Modulating the unfolded protein response (UPR) can induce protective dedifferentiation of β-cells in non-obese diabetic mice. Here, the authors show that β-cell deletion of UPR transcription factor XB...
www.nature.com
November 26, 2025 at 2:28 PM
Our new paper is out now in Nature Communications! We uncovered the function of XBP1 in beta cells of a preclinical model of T1D and identified unique and shared gene regulatory networks driven by IRE1 and XBP1.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rebecca Hull-Meichle
CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta.
youtu.be/UlHn_1Fz3ck?...
youtu.be/UlHn_1Fz3ck?...
#1 Islets in a Pod with Dr. Patrick MacDonald
YouTube video by CIRTN-R2FIC
youtu.be
November 25, 2025 at 4:01 PM
CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta.
youtu.be/UlHn_1Fz3ck?...
youtu.be/UlHn_1Fz3ck?...
Reposted by Rebecca Hull-Meichle
Islet Biologists in 🇨🇦 🏆 @cirtn.bsky.social
November 26, 2025 at 3:45 AM
Islet Biologists in 🇨🇦 🏆 @cirtn.bsky.social
Excited to have the 2025 CIRTN meeting underway. Great presentation from Victoria Johnston in our lab (her first conference!!) @cirtn.bsky.social
November 24, 2025 at 2:06 PM
Excited to have the 2025 CIRTN meeting underway. Great presentation from Victoria Johnston in our lab (her first conference!!) @cirtn.bsky.social
Reposted by Rebecca Hull-Meichle
Extraislet β cells are virtually absent in the human #T1D pancreas www.science.org/doi/10.1126/...
www.science.org
November 12, 2025 at 7:24 PM
Extraislet β cells are virtually absent in the human #T1D pancreas www.science.org/doi/10.1126/...
Reposted by Rebecca Hull-Meichle
Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglec-liposomes are a multivalent and modular platform for profiling Siglec ligands and modulating immune cell function.
www.science.org
November 12, 2025 at 9:59 PM
Reposted by Rebecca Hull-Meichle
We are delighted to host the 2nd Annual Susie Clee Memorial Lecture this Thursday 4pm PST which will be given by Dr Melkem Kebede of the University of Sydney.
November 11, 2025 at 11:21 PM
We are delighted to host the 2nd Annual Susie Clee Memorial Lecture this Thursday 4pm PST which will be given by Dr Melkem Kebede of the University of Sydney.
Reposted by Rebecca Hull-Meichle
🩺❓What is medical misinformation? And how the heck does it spread so fast? Hear and discuss with our panel of experts about the current landscape of medical misinformation, and what practical, personal steps you can take to stop it.
This event is virtual! Join from anywhere!
RSVP: zurl.co/tZ8rW
This event is virtual! Join from anywhere!
RSVP: zurl.co/tZ8rW
November 8, 2025 at 5:14 PM
🩺❓What is medical misinformation? And how the heck does it spread so fast? Hear and discuss with our panel of experts about the current landscape of medical misinformation, and what practical, personal steps you can take to stop it.
This event is virtual! Join from anywhere!
RSVP: zurl.co/tZ8rW
This event is virtual! Join from anywhere!
RSVP: zurl.co/tZ8rW
Reposted by Rebecca Hull-Meichle
Save the date for #GIA2026 (Nov. 5-6, 2026) which will feature free #glycotime talks by @carolynbertozzi.bskyverified.social , Dr. Mia Huang and more!
November 8, 2025 at 12:38 AM
Save the date for #GIA2026 (Nov. 5-6, 2026) which will feature free #glycotime talks by @carolynbertozzi.bskyverified.social , Dr. Mia Huang and more!
Reposted by Rebecca Hull-Meichle
🎃 Happy Halloween! Enjoy some sweet, glucose-filled treats tonight—and speaking of glucose, meet Canada Excellence Research Chair Dr. Rebecca Hull-Meichle, who studies glycosaminoglycans in the pancreas 🧬. Catch her talk soon at GIA2025! @rlhull-meichle.bsky.social #GIA2025 #glycotime
November 1, 2025 at 1:28 AM
🎃 Happy Halloween! Enjoy some sweet, glucose-filled treats tonight—and speaking of glucose, meet Canada Excellence Research Chair Dr. Rebecca Hull-Meichle, who studies glycosaminoglycans in the pancreas 🧬. Catch her talk soon at GIA2025! @rlhull-meichle.bsky.social #GIA2025 #glycotime
Reposted by Rebecca Hull-Meichle
🧵(1/7)We are now out of September🍁! From the last two weeks we have had publications from the CIRTN labs of Drs Jenny Bruin, Mourad Ferdaoussi, Peter Light, Patrick MacDonald, James Shapiro and Bruce Verchere!
October 1, 2025 at 8:50 PM
🧵(1/7)We are now out of September🍁! From the last two weeks we have had publications from the CIRTN labs of Drs Jenny Bruin, Mourad Ferdaoussi, Peter Light, Patrick MacDonald, James Shapiro and Bruce Verchere!
Reposted by Rebecca Hull-Meichle
Friday September 26 @uoftmedicine.bsky.social @sinaihealth.bsky.social The 2025 Gerard N Burrow Lecture. Professor Alvin Powers #islets #diabetes #T1D #T2D @vubasicsciences.bsky.social 8 am Mt. Sinai Join us!
September 19, 2025 at 7:24 PM
Friday September 26 @uoftmedicine.bsky.social @sinaihealth.bsky.social The 2025 Gerard N Burrow Lecture. Professor Alvin Powers #islets #diabetes #T1D #T2D @vubasicsciences.bsky.social 8 am Mt. Sinai Join us!
Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com
September 18, 2025 at 10:56 PM
Save the date for the 2026 A-BC Islet Biology meeting! Looking forward to many fantastic presentations by trainees in islet biology from all over Canada as well as great keynote lectures. Please share widely! isletmeeting.weebly.com
Reposted by Rebecca Hull-Meichle
Celebrating the 60th Anniversary of @diabetologiajnl.bsky.social Diabetologia - the flagship journal of @easdnews.bsky.social the European Association for the Study of Diabetes! Thanks to our colleagues at the American Diabetes Association and Diabetes Care AND it’s editor-in-chief - Steve Kahn
September 15, 2025 at 5:36 PM
Celebrating the 60th Anniversary of @diabetologiajnl.bsky.social Diabetologia - the flagship journal of @easdnews.bsky.social the European Association for the Study of Diabetes! Thanks to our colleagues at the American Diabetes Association and Diabetes Care AND it’s editor-in-chief - Steve Kahn
Reposted by Rebecca Hull-Meichle
🧵(1/3) Our first post highlighting publications coming from CIRTN groups (first half of September 2025)! We have works from the labs of Drs. Marc Prentki, Timothy Kieffer and Mathieu Ferron.
1)“From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony” PMID 40912231
1)“From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony” PMID 40912231
September 15, 2025 at 8:57 PM
🧵(1/3) Our first post highlighting publications coming from CIRTN groups (first half of September 2025)! We have works from the labs of Drs. Marc Prentki, Timothy Kieffer and Mathieu Ferron.
1)“From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony” PMID 40912231
1)“From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony” PMID 40912231
Reposted by Rebecca Hull-Meichle
The 2025 Claude Bernard Prize Awardee the brilliant Andrew Hattersley @exeter.ac.uk @easdnews.bsky.social #Genetics Scholar and gentleman #diabetes
September 16, 2025 at 7:11 AM
The 2025 Claude Bernard Prize Awardee the brilliant Andrew Hattersley @exeter.ac.uk @easdnews.bsky.social #Genetics Scholar and gentleman #diabetes
Reposted by Rebecca Hull-Meichle
My awesome Drosophila colleague Akhila Rajan at Fred Hutch (Seattle) is recruiting both a staff scientist and a postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs/30062/j...
Fred Hutchinson Cancer Center
Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.
careers-fhcrc.icims.com
September 17, 2025 at 1:05 AM
My awesome Drosophila colleague Akhila Rajan at Fred Hutch (Seattle) is recruiting both a staff scientist and a postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs/30062/j...
Reposted by Rebecca Hull-Meichle
Hello! Welcome to the CIRTN-R2FIC BlueSky account! Our group focuses on researching pancreatic islet biology and pathology related to islets such as type 1 and type 2 diabetes.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.
September 12, 2025 at 9:12 PM
Hello! Welcome to the CIRTN-R2FIC BlueSky account! Our group focuses on researching pancreatic islet biology and pathology related to islets such as type 1 and type 2 diabetes.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.
So proud to be celebrating @sekahn.bsky.social at his Banting Lecture at the ADA Scientific sessions
June 22, 2025 at 3:36 PM
So proud to be celebrating @sekahn.bsky.social at his Banting Lecture at the ADA Scientific sessions
Reposted by Rebecca Hull-Meichle
Reposted by Rebecca Hull-Meichle
When they say "America first," they don't mention that this means America will be first among nations in preventable deaths.
NEW: An NIH policy coming in the next week will target — and at least temporarily stop — funding outside the US, threatening thousands of projects and collaborations on topics like infectious diseases and cancer.
Some NIH staff have already been told to hold all subaward funds for foreign labs.
Some NIH staff have already been told to hold all subaward funds for foreign labs.
Exclusive: NIH to suspend funds for research abroad as it overhauls policy
Move by US biomedical agency threatens thousands of projects on infectious diseases, cancer and more.
www.nature.com
May 1, 2025 at 12:03 AM
When they say "America first," they don't mention that this means America will be first among nations in preventable deaths.
Reposted by Rebecca Hull-Meichle
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 6:03 PM
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Reposted by Rebecca Hull-Meichle
Reposted by Rebecca Hull-Meichle
“Recruiting U.S. scientists is a fine idea – except we’re barely supporting Canadian scientists as it is”
https://www.theglobeandmail.com/gift/aaa9fec50b2b595cc0291494fc97e4bd10e7d6945d5c457e0bfa75d42846a705/4FRDBEKLNFESVJ3ZILAS36KR7Y
https://www.theglobeandmail.com/gift/aaa9fec50b2b595cc0291494fc97e4bd10e7d6945d5c457e0bfa75d42846a705/4FRDBEKLNFESVJ3ZILAS36KR7Y
April 19, 2025 at 12:12 PM
“Recruiting U.S. scientists is a fine idea – except we’re barely supporting Canadian scientists as it is”
https://www.theglobeandmail.com/gift/aaa9fec50b2b595cc0291494fc97e4bd10e7d6945d5c457e0bfa75d42846a705/4FRDBEKLNFESVJ3ZILAS36KR7Y
https://www.theglobeandmail.com/gift/aaa9fec50b2b595cc0291494fc97e4bd10e7d6945d5c457e0bfa75d42846a705/4FRDBEKLNFESVJ3ZILAS36KR7Y
Reposted by Rebecca Hull-Meichle
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Join Us! | King Lab
Are you interested in joining the King Lab? More information here!
www.zoology.ubc.ca
March 31, 2025 at 1:22 AM
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...