Andy Rosser
@realandyrosser.bsky.social
Consultant in Infectious Diseases and Medical Microbiology. Interests inc TB and new antibiotics. My posts are my own views and mine alone
Reposted by Andy Rosser
Caring for patients with bronchiectasis poses a challenge for both pulmonologists and #AMSky teams.
Standard 14d treatments for exacerbations lack good evidence support.
This small RCT favors shorter durations such as 8d 👉🏻 publications.ersnet.org/content/erj/... #IDsky @bradspellberg.bsky.social
Standard 14d treatments for exacerbations lack good evidence support.
This small RCT favors shorter durations such as 8d 👉🏻 publications.ersnet.org/content/erj/... #IDsky @bradspellberg.bsky.social
May 4, 2025 at 12:43 AM
Caring for patients with bronchiectasis poses a challenge for both pulmonologists and #AMSky teams.
Standard 14d treatments for exacerbations lack good evidence support.
This small RCT favors shorter durations such as 8d 👉🏻 publications.ersnet.org/content/erj/... #IDsky @bradspellberg.bsky.social
Standard 14d treatments for exacerbations lack good evidence support.
This small RCT favors shorter durations such as 8d 👉🏻 publications.ersnet.org/content/erj/... #IDsky @bradspellberg.bsky.social
Reposted by Andy Rosser
Targeting chronic biofilm infections with patient-derived phages: an in vitro and ex vivo proof-of-concept study in patients with left ventricular assist devices
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Targeting chronic biofilm infections with patient-derived phages: an in vitro and ex vivo proof-of-concept study in patients with left ventricular assist devices
Phage therapy is being reconsidered as a valuable approach to combat antimicrobial resistance.
doi.org
March 30, 2025 at 9:11 PM
Targeting chronic biofilm infections with patient-derived phages: an in vitro and ex vivo proof-of-concept study in patients with left ventricular assist devices
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted by Andy Rosser
Diagnosing #LongCOVID (LC) remains a challenge. New study in #China shows with #Omicron infection:
🦠7.8% developed LC in 1 year
🦠Risk of LC rose with #reinfection dose-dependently
🦠Persistent LC comes with higher levels of leukocytes, triglycerides, fibrinogen & myoglobin
🔗Full text #IDSky #COVID
🦠7.8% developed LC in 1 year
🦠Risk of LC rose with #reinfection dose-dependently
🦠Persistent LC comes with higher levels of leukocytes, triglycerides, fibrinogen & myoglobin
🔗Full text #IDSky #COVID
Health outcomes one year after Omicron infection among 12,789 adults: a community-based cross-sectional study
The considerable health burden of long COVID and the progression of neurological symptoms
following Omicron infection warrant close monitoring. Utilizing professional questionnaires
and developing rel...
www.thelancet.com
March 30, 2025 at 10:59 PM
Diagnosing #LongCOVID (LC) remains a challenge. New study in #China shows with #Omicron infection:
🦠7.8% developed LC in 1 year
🦠Risk of LC rose with #reinfection dose-dependently
🦠Persistent LC comes with higher levels of leukocytes, triglycerides, fibrinogen & myoglobin
🔗Full text #IDSky #COVID
🦠7.8% developed LC in 1 year
🦠Risk of LC rose with #reinfection dose-dependently
🦠Persistent LC comes with higher levels of leukocytes, triglycerides, fibrinogen & myoglobin
🔗Full text #IDSky #COVID
Reposted by Andy Rosser
@wiki-guidelines.bsky.social is launching a bacteremia guideline! If not previously signed up, and wish to participate, use the link below to submit your application. You will then be provided with a link to sign-up for the bacteremia one.
forms.office.com/r/Tyb8R0iM8X
forms.office.com/r/Tyb8R0iM8X
Microsoft Forms
forms.office.com
February 5, 2025 at 10:59 PM
@wiki-guidelines.bsky.social is launching a bacteremia guideline! If not previously signed up, and wish to participate, use the link below to submit your application. You will then be provided with a link to sign-up for the bacteremia one.
forms.office.com/r/Tyb8R0iM8X
forms.office.com/r/Tyb8R0iM8X
Reposted by Andy Rosser
The Fungitell serum (1-3)-β-D-glucan (BDG) assay is one non-invasive test; however, it only has moderate sensitivity and specificity. Selecting which patients to test and subsequently correctly interpreting the results is essential. #idsky
🆕💫 @cmicomms.bsky.social
@drtoddlee.bsky.social @dremilymcd.bsky.social
Optimizing use of the (1-3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jirovecii Pneumonia.
PCP Score 👇🌟
cc @bradspellberg.bsky.social
#idsky
www.sciencedirect.com/science/arti...
@drtoddlee.bsky.social @dremilymcd.bsky.social
Optimizing use of the (1-3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jirovecii Pneumonia.
PCP Score 👇🌟
cc @bradspellberg.bsky.social
#idsky
www.sciencedirect.com/science/arti...
February 3, 2025 at 4:54 AM
The Fungitell serum (1-3)-β-D-glucan (BDG) assay is one non-invasive test; however, it only has moderate sensitivity and specificity. Selecting which patients to test and subsequently correctly interpreting the results is essential. #idsky
Reposted by Andy Rosser
Residual symptoms and quality of life after treated Lyme neuroborreliosis: case-control study (QoLYME)
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Residual symptoms and quality of life after treated Lyme neuroborreliosis: case-control study (QoLYME)
Earlier studies revealed that 10-50% of patients reported remaining complaints after treatment for Lyme neuroborreliosis (LNB). The aim of our study was to assess and compare symptoms and quality of life of patients diagnosed and treated for LNB with general population.
buff.ly
January 31, 2025 at 3:33 PM
Residual symptoms and quality of life after treated Lyme neuroborreliosis: case-control study (QoLYME)
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted by Andy Rosser
Not good news: @who.int just announced a new Marburg outbreak in Tanzania.
“As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.”
🧪 #IDsky
www.who.int/emergencies/...
“As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.”
🧪 #IDsky
www.who.int/emergencies/...
Outbreak of suspected Marburg Virus Disease– United Republic of Tanzania
www.who.int
January 14, 2025 at 11:06 PM
Not good news: @who.int just announced a new Marburg outbreak in Tanzania.
“As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.”
🧪 #IDsky
www.who.int/emergencies/...
“As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.”
🧪 #IDsky
www.who.int/emergencies/...
Reposted by Andy Rosser
The utility of 2-[18F]FDG PET in evaluating disseminated nontuberculous mycobacterial infection in patients with anti-interferon-? autoantibodies
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
The utility of 2-[18F]FDG PET in evaluating disseminated nontuberculous mycobacterial infection in patients with anti-interferon-γ autoantibodies
Managing disseminated nontuberculous mycobacterial (NTM) infection in patients with neutralizing anti-interferon-γ autoantibodies (AIGA) poses substantial challenges due to the lack of established treatment guidance and predictive tools for clinical outcomes.
buff.ly
December 18, 2024 at 10:11 PM
The utility of 2-[18F]FDG PET in evaluating disseminated nontuberculous mycobacterial infection in patients with anti-interferon-? autoantibodies
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted by Andy Rosser
#IDSky - first paper from us on bluesky. What are the longer term quality of life issues after bloodstream infection in people who inject drugs? Here are some data!
www.journalofinfection.com/article/S016...
www.journalofinfection.com/article/S016...
Health associated quality of life impairment in People who inject drugs (PWID) after blood stream infection.
People who inject drugs (PWID) have high rates of blood stream infections (BSI) with Staphylococcus aureus (SA) and group A streptococcus (GAS). Little is known about health related quality of life outcomes after BSI.
www.journalofinfection.com
December 17, 2024 at 9:33 AM
#IDSky - first paper from us on bluesky. What are the longer term quality of life issues after bloodstream infection in people who inject drugs? Here are some data!
www.journalofinfection.com/article/S016...
www.journalofinfection.com/article/S016...
Reposted by Andy Rosser
This one flew under the radar, but trust me, it’s a must-read! The article raises a point we really need to talk about—something that might change your practice. What’s your take on it?
Let’s dive in #idsky #medsky #EMIMCC
Let’s dive in #idsky #medsky #EMIMCC
Are we jumping the gun? 🧪
A 🆕💫 retrospective study shows higher mortality rate in patients with KPC Klebsiella BSIs treated with renal-adjusted doses ceftazidime-avibactam regardless of kidney disease status
Time to rethink our dosing strategy? #idsky #medsky #EMIMCC
academic.oup.com/jacamr/artic...
A 🆕💫 retrospective study shows higher mortality rate in patients with KPC Klebsiella BSIs treated with renal-adjusted doses ceftazidime-avibactam regardless of kidney disease status
Time to rethink our dosing strategy? #idsky #medsky #EMIMCC
academic.oup.com/jacamr/artic...
Impact of renal-adjusted ceftazidime/avibactam in patients with KPC-producing Klebsiella pneumoniae bloodstream infection: a retrospective cohort study
AbstractBackground. Bloodstream infections (BSIs) caused by KPC-producing Klebsiella pneumoniae (KPC-Kp) are still associated with high mortality, and the
academic.oup.com
December 18, 2024 at 11:19 AM
Reposted by Andy Rosser
Really pleased to share collaborative project led by @emilybethwong.bsky.social & 1st author
@maphemthembu.bsky.social
A careful dissection of dysfunctional immune responses in ART-naive HIV infection. TL:DR bronchoalveolar ≠ blood responses
#HIVSky #IDSky #ImmunoSky
www.cell.com/iscience/ful...
@maphemthembu.bsky.social
A careful dissection of dysfunctional immune responses in ART-naive HIV infection. TL:DR bronchoalveolar ≠ blood responses
#HIVSky #IDSky #ImmunoSky
www.cell.com/iscience/ful...
Dysfunctional bronchoalveolar effector memory CD8+ T cells in tuberculosis-exposed people living with antiretroviral-naïve HIV infection
Immunology; Virology
www.cell.com
December 5, 2024 at 1:32 PM
Really pleased to share collaborative project led by @emilybethwong.bsky.social & 1st author
@maphemthembu.bsky.social
A careful dissection of dysfunctional immune responses in ART-naive HIV infection. TL:DR bronchoalveolar ≠ blood responses
#HIVSky #IDSky #ImmunoSky
www.cell.com/iscience/ful...
@maphemthembu.bsky.social
A careful dissection of dysfunctional immune responses in ART-naive HIV infection. TL:DR bronchoalveolar ≠ blood responses
#HIVSky #IDSky #ImmunoSky
www.cell.com/iscience/ful...
Has anyone used an AI scribe such as Heidi?
December 2, 2024 at 9:11 PM
Has anyone used an AI scribe such as Heidi?
Reposted by Andy Rosser
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Virtual Home Care for Patients With Acute Illness
This cohort study compares outcomes of patients receiving care in an outpatient, virtual, home-based acute care model with outcomes of patients receiving standard hospital care.
jamanetwork.com
November 30, 2024 at 9:24 PM
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Pubmed.ncbi.nlm.nih.gov/24243988
Sometimes you can try rifabutin... Don't always have to reach for bedaquiline
Sometimes you can try rifabutin... Don't always have to reach for bedaquiline
Safety of rifabutin replacing rifampicin in the treatment of tuberculosis: a single-centre retrospective cohort study - PubMed
Rifabutin replacing rifampicin was well tolerated in most adults who had rifampicin-related ARs. Females and those with HCV or HBV coinfection were more prone to rifabutin-related severe ARs and requi...
Pubmed.ncbi.nlm.nih.gov
December 2, 2024 at 4:49 PM
Pubmed.ncbi.nlm.nih.gov/24243988
Sometimes you can try rifabutin... Don't always have to reach for bedaquiline
Sometimes you can try rifabutin... Don't always have to reach for bedaquiline
Reposted by Andy Rosser
The SARS-CoV-2 spike protein can persist in the brain—in the skull bone marrow and meninges—to induce neurologic damage
www.cell.com/cell-host-mi... open-access
www.cell.com/cell-host-mi... open-access
November 29, 2024 at 3:39 PM
The SARS-CoV-2 spike protein can persist in the brain—in the skull bone marrow and meninges—to induce neurologic damage
www.cell.com/cell-host-mi... open-access
www.cell.com/cell-host-mi... open-access
Reposted by Andy Rosser
Vito beat out nearly 2,000 other dogs to become the first pug to win the National Dog Show. The two-year-old pup became a sensation on Thursday, when the competition, which was held earlier this month, was broadcast on NBC after the Macy’s Thanksgiving Day Parade. www.nytimes.com/2024/11/29/u...
November 29, 2024 at 8:19 PM
Vito beat out nearly 2,000 other dogs to become the first pug to win the National Dog Show. The two-year-old pup became a sensation on Thursday, when the competition, which was held earlier this month, was broadcast on NBC after the Macy’s Thanksgiving Day Parade. www.nytimes.com/2024/11/29/u...
So far AI useful for:
- Replacing a quick google search for fact checking
- Reviewing differential diagnoses in difficult cases
- Planning holiday in outline
- Converting my wife's verbal shopping list into something ordered and efficient for the supermarket
- Replacing a quick google search for fact checking
- Reviewing differential diagnoses in difficult cases
- Planning holiday in outline
- Converting my wife's verbal shopping list into something ordered and efficient for the supermarket
November 23, 2024 at 4:44 PM
So far AI useful for:
- Replacing a quick google search for fact checking
- Reviewing differential diagnoses in difficult cases
- Planning holiday in outline
- Converting my wife's verbal shopping list into something ordered and efficient for the supermarket
- Replacing a quick google search for fact checking
- Reviewing differential diagnoses in difficult cases
- Planning holiday in outline
- Converting my wife's verbal shopping list into something ordered and efficient for the supermarket
