Rune Busk Damgaard
@rbdamgaard.bsky.social
Associate Professor, Section for Medical Biotechnology, Technical University of Denmark. Studies ubiquitin signalling in inflammation, metabolism, and disease.
Reposted by Rune Busk Damgaard
🚨 Postdoc position in my lab!
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
November 21, 2025 at 4:44 PM
🚨 Postdoc position in my lab!
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
🚨 Postdoc position in my lab!
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
November 21, 2025 at 4:44 PM
🚨 Postdoc position in my lab!
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
A project on protein binder discovery for K6-linked #ubiquitin to investigate their role in infection is available.
📍 DTU, Copenhagen, Denmark
⏰ Deadline: 18 December 2025
Apply here: efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
A #postdoc position in atypical #ubiquitin signalling and protein binder engineering is opening soon in my lab at DTU Bioengineering! Get in touch if you are interested.
October 30, 2025 at 2:13 PM
A #postdoc position in atypical #ubiquitin signalling and protein binder engineering is opening soon in my lab at DTU Bioengineering! Get in touch if you are interested.
🚀 Off to our Research Retreat with the Section for Medical Biotechnology, DTU Biotechnology and Biomedicine.
Two days of science, ideas & innovation 🧬💡
12 faculty pitches, 30+ PhDs & postdocs, and endless opportunities for new collaborations 🔬🤝✨
Two days of science, ideas & innovation 🧬💡
12 faculty pitches, 30+ PhDs & postdocs, and endless opportunities for new collaborations 🔬🤝✨
October 7, 2025 at 10:06 AM
🚀 Off to our Research Retreat with the Section for Medical Biotechnology, DTU Biotechnology and Biomedicine.
Two days of science, ideas & innovation 🧬💡
12 faculty pitches, 30+ PhDs & postdocs, and endless opportunities for new collaborations 🔬🤝✨
Two days of science, ideas & innovation 🧬💡
12 faculty pitches, 30+ PhDs & postdocs, and endless opportunities for new collaborations 🔬🤝✨
Reposted by Rune Busk Damgaard
A few months ago, our review “The Molecular Toolbox for Linkage Type-Specific Analysis of Ubiquitin Signaling” 🧬🧰🛠️ came out in ChemBioChem. Time to give it a spotlight!
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
September 16, 2025 at 7:45 AM
A few months ago, our review “The Molecular Toolbox for Linkage Type-Specific Analysis of Ubiquitin Signaling” 🧬🧰🛠️ came out in ChemBioChem. Time to give it a spotlight!
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
A few months ago, our review “The Molecular Toolbox for Linkage Type-Specific Analysis of Ubiquitin Signaling” 🧬🧰🛠️ came out in ChemBioChem. Time to give it a spotlight!
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
September 16, 2025 at 7:45 AM
A few months ago, our review “The Molecular Toolbox for Linkage Type-Specific Analysis of Ubiquitin Signaling” 🧬🧰🛠️ came out in ChemBioChem. Time to give it a spotlight!
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
chemistry-europe.onlinelibrary.wiley.com/doi/full/10....
Is it still useful to insist that authors spell out every protein name in research papers? Many names are long, obscure, and say nothing about function... we might as well call them James, Joan, and John.
August 14, 2025 at 12:09 PM
Is it still useful to insist that authors spell out every protein name in research papers? Many names are long, obscure, and say nothing about function... we might as well call them James, Joan, and John.
Reposted by Rune Busk Damgaard
The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.
August 13, 2025 at 5:28 PM
The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.
Reposted by Rune Busk Damgaard
Jeg er godt træt af måden regeringens spareplan rammer universiteterne.
Regeringens sult efter at afskaffe bureaukratiet er gået for vidt, når den nu rammer forskerne
Regeringen hævder, at der med de nye besparelser på universiteterne ikke vil gå midler fra forskning. Men forskere arbejder ikke i et vakuum. Når administrationen fjernes, ryger tiden fra forskningen
klik1.information.dk
July 3, 2025 at 10:33 AM
Jeg er godt træt af måden regeringens spareplan rammer universiteterne.
Reposted by Rune Busk Damgaard
the really key number to remember is that biorxiv serves the entire global science community, posting thousands of papers per month for millions of readers, and it's entire running costs ( a few $M/year) are less than some single labs....
July 2, 2025 at 6:27 PM
the really key number to remember is that biorxiv serves the entire global science community, posting thousands of papers per month for millions of readers, and it's entire running costs ( a few $M/year) are less than some single labs....
Reposted by Rune Busk Damgaard
it’s a global contest, whether we want to compete or watch from the sidelines
May 23, 2025 at 4:23 PM
it’s a global contest, whether we want to compete or watch from the sidelines
Reposted by Rune Busk Damgaard
Special day for our group @cbmr.science as we celebrate the successful defense of our (first) freshly minted PhD, Dr. Conchita Bringas 🥳 Her thesis was based on characterizing novel #AMPK inhibitors. Special thanks to the great committee @rbdamgaard.bsky.social ,Dave Carling & Lykke Sylow.
May 16, 2025 at 6:35 PM
Special day for our group @cbmr.science as we celebrate the successful defense of our (first) freshly minted PhD, Dr. Conchita Bringas 🥳 Her thesis was based on characterizing novel #AMPK inhibitors. Special thanks to the great committee @rbdamgaard.bsky.social ,Dave Carling & Lykke Sylow.
Reposted by Rune Busk Damgaard
We have a 4-year postdoc position open in our Research Unit on proteostasis!
The project explores inter-tissue regulation using advanced proteomics approaches.
Collaborative & interdisciplinary environment. More details & application here:
jobs-uk-koeln.onlyfy.jobs/job/pktg6ivj...
The project explores inter-tissue regulation using advanced proteomics approaches.
Collaborative & interdisciplinary environment. More details & application here:
jobs-uk-koeln.onlyfy.jobs/job/pktg6ivj...
Postdoc Position (f/m/x)
We are looking to support our rapidly growing team as soon as possible:
jobs-uk-koeln.onlyfy.jobs
May 15, 2025 at 10:01 AM
We have a 4-year postdoc position open in our Research Unit on proteostasis!
The project explores inter-tissue regulation using advanced proteomics approaches.
Collaborative & interdisciplinary environment. More details & application here:
jobs-uk-koeln.onlyfy.jobs/job/pktg6ivj...
The project explores inter-tissue regulation using advanced proteomics approaches.
Collaborative & interdisciplinary environment. More details & application here:
jobs-uk-koeln.onlyfy.jobs/job/pktg6ivj...
Reposted by Rune Busk Damgaard
Great to see this out. A story that spanned continents, cities and budget codes…
www.nature.com/articles/s41...
Big thanks to all the teams involved!
@clausenlab.bsky.social @e3chembio.bsky.social
www.nature.com/articles/s41...
Big thanks to all the teams involved!
@clausenlab.bsky.social @e3chembio.bsky.social
ATP functions as a pathogen-associated molecular pattern to activate the E3 ubiquitin ligase RNF213 - Nature Communications
RNF213 is an E3 ligase with ATPase activity. Here, the authors show that RNF213 is activated by ATP binding and senses cellular energy states, and reveal a transthiolation mechanism induced by immune ...
www.nature.com
May 13, 2025 at 9:51 AM
Great to see this out. A story that spanned continents, cities and budget codes…
www.nature.com/articles/s41...
Big thanks to all the teams involved!
@clausenlab.bsky.social @e3chembio.bsky.social
www.nature.com/articles/s41...
Big thanks to all the teams involved!
@clausenlab.bsky.social @e3chembio.bsky.social
Haven’t shared this in a while. But the #ubiquitin and #ubl Starter Pack now includes 116 profiles to follow if you’re interested in the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.
May 13, 2025 at 10:04 AM
Haven’t shared this in a while. But the #ubiquitin and #ubl Starter Pack now includes 116 profiles to follow if you’re interested in the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.
Reposted by Rune Busk Damgaard
Happy to see our review out in ChemBioChem @chemistryeurope.bsky.social in which we describe the tools and strategies for deciphering linkage type-specific #ubiquitin signalling: doi.org/10.1002/cbic.... Thanks to Julian for spearheading this, and to Camilla and Dominik for important contributions.
April 22, 2025 at 11:31 AM
Happy to see our review out in ChemBioChem @chemistryeurope.bsky.social in which we describe the tools and strategies for deciphering linkage type-specific #ubiquitin signalling: doi.org/10.1002/cbic.... Thanks to Julian for spearheading this, and to Camilla and Dominik for important contributions.
Happy to see our review out in ChemBioChem @chemistryeurope.bsky.social in which we describe the tools and strategies for deciphering linkage type-specific #ubiquitin signalling: doi.org/10.1002/cbic.... Thanks to Julian for spearheading this, and to Camilla and Dominik for important contributions.
April 22, 2025 at 11:31 AM
Happy to see our review out in ChemBioChem @chemistryeurope.bsky.social in which we describe the tools and strategies for deciphering linkage type-specific #ubiquitin signalling: doi.org/10.1002/cbic.... Thanks to Julian for spearheading this, and to Camilla and Dominik for important contributions.
Reposted by Rune Busk Damgaard
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
March 17, 2025 at 8:58 PM
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
Reposted by Rune Busk Damgaard
Reposted by Rune Busk Damgaard
Nysgerrighedsdrevet, uafhængig forskning er en samfundssøjle - i disse tider er det mere tydeligt end nogensinde. Og EU har en særlig vigtig rolle.
European Research Council må ikke blive udvandet ifm forhandlingerne om EU’s forskningsbudget. ERC skal forblive en uafhængig enhed, der investerer i nysgerrighedsdreven forskning - for det er grundlaget for de nye indsigter, der driver vores samfund fremad. www.information.dk/debat/2025/0...
Danske politikere må forsvare EU’s succesprogram for grundforskning
EU’s program, der siden 2007 har støttet de bedste forskningsprojekter i Europa, er potentielt i fare. Hvis pengene i stedet går til projekter ud fra vurderet markedspotentiale, vil det koste på EU’s ...
www.information.dk
March 5, 2025 at 9:04 AM
Nysgerrighedsdrevet, uafhængig forskning er en samfundssøjle - i disse tider er det mere tydeligt end nogensinde. Og EU har en særlig vigtig rolle.
Reposted by Rune Busk Damgaard
Ny kronik fra DUA i Dagbladet Information på baggrund af de verserende rygter om at ville indføre større politisk styring og strategisk prioritering af midlerne i ERC.
I Det Unge Akademi har vi forfattet et åbent brev til de danske EU-parlamentarikere samt uddannelses- og forskningsministeren om at værne om ERC og den frie, nysgerrige forskning i Europa.
www.information.dk/debat/2025/0...
www.information.dk/debat/2025/0...
Danske politikere må forsvare EU’s succesprogram for grundforskning
EU’s program, der siden 2007 har støttet de bedste forskningsprojekter i Europa, er potentielt i fare. Hvis pengene i stedet går til projekter ud fra vurderet markedspotentiale, vil det koste på EU’s ...
www.information.dk
March 4, 2025 at 7:35 PM
Ny kronik fra DUA i Dagbladet Information på baggrund af de verserende rygter om at ville indføre større politisk styring og strategisk prioritering af midlerne i ERC.
Reposted by Rune Busk Damgaard
European Research Council må ikke blive udvandet ifm forhandlingerne om EU’s forskningsbudget. ERC skal forblive en uafhængig enhed, der investerer i nysgerrighedsdreven forskning - for det er grundlaget for de nye indsigter, der driver vores samfund fremad. www.information.dk/debat/2025/0...
Danske politikere må forsvare EU’s succesprogram for grundforskning
EU’s program, der siden 2007 har støttet de bedste forskningsprojekter i Europa, er potentielt i fare. Hvis pengene i stedet går til projekter ud fra vurderet markedspotentiale, vil det koste på EU’s ...
www.information.dk
March 5, 2025 at 8:27 AM
European Research Council må ikke blive udvandet ifm forhandlingerne om EU’s forskningsbudget. ERC skal forblive en uafhængig enhed, der investerer i nysgerrighedsdreven forskning - for det er grundlaget for de nye indsigter, der driver vores samfund fremad. www.information.dk/debat/2025/0...
What determines if a preprint from @biorxivpreprint.bsky.social is also indexed in PubMed? It appears some are, but others aren’t. Our recent preprint for some reason isn’t. Does one have to opt into that? Or how does it work?
February 21, 2025 at 1:23 PM
What determines if a preprint from @biorxivpreprint.bsky.social is also indexed in PubMed? It appears some are, but others aren’t. Our recent preprint for some reason isn’t. Does one have to opt into that? Or how does it work?
Reposted by Rune Busk Damgaard
Autophagy UK & Proteostasis UK joint meeting -June 3-5. Exploring the lifecycle of cellular components from synthesis to degradation. Going to be a great meeting and we look forward to welcoming you to Dundee! Exciting lineup of speakers and opportunities for ECRs
Register here: tinyurl.com/mr3p49f9
Register here: tinyurl.com/mr3p49f9
Joint 2025 Autophagy UK and Proteostasis UK conference | University of Dundee, UK
Welcome to the 2025 joint “Autophagy UK and Proteostasis UK” conference!
tinyurl.com
February 16, 2025 at 6:56 AM
Autophagy UK & Proteostasis UK joint meeting -June 3-5. Exploring the lifecycle of cellular components from synthesis to degradation. Going to be a great meeting and we look forward to welcoming you to Dundee! Exciting lineup of speakers and opportunities for ECRs
Register here: tinyurl.com/mr3p49f9
Register here: tinyurl.com/mr3p49f9
Reposted by Rune Busk Damgaard
Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up! www.nature.com/articles/s41...
C-terminal amides mark proteins for degradation via SCF–FBXO31 - Nature
SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.
www.nature.com
January 30, 2025 at 12:30 PM
Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up! www.nature.com/articles/s41...