Raúl Pelayo
@raulpelayo.bsky.social
Reposted by Raúl Pelayo
Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases.
A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89
A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89
December 16, 2025 at 12:33 PM
Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases.
A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89
A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89
Reposted by Raúl Pelayo
El Dr. Raúl Pelayo i el Dr. Edgar Buloz de l'Institut Guttmann, han participat a l'acte dels 25 anys d’ @acafssc.bsky.social , on també s'ha presentat el Comitè Científic de la Fundació 12 de Maig, del qual tots dos formen part, per impulsar recerca i atenció en #fibromiàlgia i altres SSC.
December 11, 2025 at 7:10 AM
El Dr. Raúl Pelayo i el Dr. Edgar Buloz de l'Institut Guttmann, han participat a l'acte dels 25 anys d’ @acafssc.bsky.social , on també s'ha presentat el Comitè Científic de la Fundació 12 de Maig, del qual tots dos formen part, per impulsar recerca i atenció en #fibromiàlgia i altres SSC.
Reposted by Raúl Pelayo
Optogenetics is poised to move from a research tool to new therapies—if scientists can show it’s safe. https://scim.ag/48VQ7gt
Can adding light sensors to nerve cells switch off pain, epilepsy, and other disorders?
Optogenetics is poised to move from a research tool to new therapies—if scientists can show it’s safe
scim.ag
December 10, 2025 at 5:51 PM
Optogenetics is poised to move from a research tool to new therapies—if scientists can show it’s safe. https://scim.ag/48VQ7gt
Reposted by Raúl Pelayo
Es la peor noticia del mundo
December 10, 2025 at 9:55 AM
Es la peor noticia del mundo
Reposted by Raúl Pelayo
In patients with idiopathic normal-pressure hydrocephalus responsive to CSF drainage, shunting improved gait and balance at 3 months, but not cognition or incontinence, and was associated with some procedure-related risks. Full PENS trial results and Research Summary: nej.md/41OfPQ5
#MedSky
#MedSky
December 9, 2025 at 2:46 PM
In patients with idiopathic normal-pressure hydrocephalus responsive to CSF drainage, shunting improved gait and balance at 3 months, but not cognition or incontinence, and was associated with some procedure-related risks. Full PENS trial results and Research Summary: nej.md/41OfPQ5
#MedSky
#MedSky
Reposted by Raúl Pelayo
New online! Physical activity could protect against cognitive decline
Physical activity could protect against cognitive decline
Nature Reviews Neurology, Published online: 08 December 2025; doi:10.1038/s41582-025-01174-8A new study indicates that physical activity reduces cognitive decline, possibly through attenuation of tau accumulation in the brain.
bit.ly
December 9, 2025 at 10:00 AM
New online! Physical activity could protect against cognitive decline
Reposted by Raúl Pelayo
New online! α-Synuclein signatures mark Parkinson disease subtypes
α-Synuclein signatures mark Parkinson disease subtypes
Nature Reviews Neurology, Published online: 08 December 2025; doi:10.1038/s41582-025-01176-6Recent research indicates that the brain-first and body-first subtypes of Parkinson disease can be distinguished by patterns of cutaneous α-synuclein deposition.
bit.ly
December 9, 2025 at 10:00 AM
New online! α-Synuclein signatures mark Parkinson disease subtypes
Reposted by Raúl Pelayo
Long thought of as support cells, astrocytes are emerging as key players in health and disease
go.nature.com/4pEKHN3
go.nature.com/4pEKHN3
The ‘silent’ brain cells that shape our behaviour, memory and health
Astrocytes make up one-quarter of the brain, but researchers are only now realizing their true value.
go.nature.com
December 7, 2025 at 10:04 AM
Long thought of as support cells, astrocytes are emerging as key players in health and disease
go.nature.com/4pEKHN3
go.nature.com/4pEKHN3
Reposted by Raúl Pelayo
PENS trial: Idiopathic normal-pressure hydrocephalus is characterized by impaired gait, balance, cognition, and bladder control. Research on the effectiveness of shunt surgery in these patients is summarized in a new Quick Take video. nej.md/44HVdu8
#MedSky #NeuroSky
#MedSky #NeuroSky
December 6, 2025 at 8:01 PM
PENS trial: Idiopathic normal-pressure hydrocephalus is characterized by impaired gait, balance, cognition, and bladder control. Research on the effectiveness of shunt surgery in these patients is summarized in a new Quick Take video. nej.md/44HVdu8
#MedSky #NeuroSky
#MedSky #NeuroSky
Reposted by Raúl Pelayo
A fantastic comprehensive review article w/ everything you need to know about Idiopathic Normal Pressure Hydrocephalus. Johnson and Williams share that idiopathic normal-pressure hydrocephalus is a common, frequently missed and potentially reversible neurologic condition in older adults. @nejm.org
December 4, 2025 at 1:48 PM
A fantastic comprehensive review article w/ everything you need to know about Idiopathic Normal Pressure Hydrocephalus. Johnson and Williams share that idiopathic normal-pressure hydrocephalus is a common, frequently missed and potentially reversible neurologic condition in older adults. @nejm.org
Reposted by Raúl Pelayo
📹El Dr. Joan Vidal i Montse Caldés, codirectora, en el #DiaInternacionaldelesPersonesambDiscapacitat, al programa Tot es mou parlant de l'acte de Lectura Pública de la Convenció sobre els Drets de les Persones amb Discapacitat.
A partir de 2h. 8min.
A partir de 2h. 8min.
Tot es mou - 03/12/2025 - 3Cat
www.3cat.cat
December 4, 2025 at 2:26 PM
📹El Dr. Joan Vidal i Montse Caldés, codirectora, en el #DiaInternacionaldelesPersonesambDiscapacitat, al programa Tot es mou parlant de l'acte de Lectura Pública de la Convenció sobre els Drets de les Persones amb Discapacitat.
A partir de 2h. 8min.
A partir de 2h. 8min.
El Dr Albu ha explicado en la de la reunión de la #SENR @seneurologia.bsky.social en Sevilla el impacto de la epilepsia y los fármacos antiepilèpticos en los pacientes con TCE en APT @iguttmann.bsky.social
November 20, 2025 at 8:59 AM
El Dr Albu ha explicado en la de la reunión de la #SENR @seneurologia.bsky.social en Sevilla el impacto de la epilepsia y los fármacos antiepilèpticos en los pacientes con TCE en APT @iguttmann.bsky.social
Reposted by Raúl Pelayo
New online! Huntington disease: somatic expansion, pathobiology and therapeutics
Huntington disease: somatic expansion, pathobiology and therapeutics
Nature Reviews Neurology, Published online: 13 November 2025; doi:10.1038/s41582-025-01159-7Genome-wide association studies have identified genetic modifiers, mostly DNA repair genes, that significantly influence the onset and progression of Huntington disease, pointing to somatic CAG repeat expansions as a key pathological driver. Here, Tabrizi and colleagues review the evidence for this paradigm and discuss the potential for therapeutic interventions.
bit.ly
November 14, 2025 at 1:42 AM
New online! Huntington disease: somatic expansion, pathobiology and therapeutics
Reposted by Raúl Pelayo
ICYMI: New online! Towards pharmacological prevention of Alzheimer disease
Towards pharmacological prevention of Alzheimer disease
Nature Reviews Neurology, Published online: 03 November 2025; doi:10.1038/s41582-025-01154-yAdvances in biomarkers, blood tests and disease-modifying therapies have created a credible path to clinical prevention of Alzheimer disease (AD). In this Perspective, the authors discuss promising approaches to the prevention of AD and highlight strategic gaps.
bit.ly
November 10, 2025 at 4:04 AM
ICYMI: New online! Towards pharmacological prevention of Alzheimer disease
Reposted by Raúl Pelayo
🧠 La Dra. Rocío Sánchez-Carrión, neuropsicòloga de l’Institut Guttmann, participa a la Jornada Multidisciplinar sobre #EncefalitisAutoimmunes amb una ponència sobre alteracions neuropsicològiques i rehabilitació integral.
November 6, 2025 at 7:45 AM
🧠 La Dra. Rocío Sánchez-Carrión, neuropsicòloga de l’Institut Guttmann, participa a la Jornada Multidisciplinar sobre #EncefalitisAutoimmunes amb una ponència sobre alteracions neuropsicològiques i rehabilitació integral.
Moltes gràcies #HospitalSantAndreu de Manresa per convidar-me a la Jornada d’EAIA’s TRASTORNS COGNITIUS CATALUNY. Ha sigut una amb molta qualitat científica i clínica. @iguttmann.bsky.social
October 31, 2025 at 1:43 PM
Moltes gràcies #HospitalSantAndreu de Manresa per convidar-me a la Jornada d’EAIA’s TRASTORNS COGNITIUS CATALUNY. Ha sigut una amb molta qualitat científica i clínica. @iguttmann.bsky.social
Reposted by Raúl Pelayo
We’re celebrating 20 years of Nature Reviews Neurology with a special Collection, including our anniversary articles, Reviews and Perspectives on high-impact research from the past 20 years, and Consensus statements, recommendations and Roadmaps. nature.com/collections/...
20 years of Nature Reviews Neurology
This special Collection celebrates the 20th anniversary of Nature Reviews Neurology, including our 20th anniversary articles, Reviews and Perspectives on the ...
nature.com
October 29, 2025 at 10:44 AM
We’re celebrating 20 years of Nature Reviews Neurology with a special Collection, including our anniversary articles, Reviews and Perspectives on high-impact research from the past 20 years, and Consensus statements, recommendations and Roadmaps. nature.com/collections/...
Reposted by Raúl Pelayo
A new review explores current ideas about the disease, with emphasis on the importance of dural venous sinus stenosis and new treatment options. Read the full review: nej.md/3KJlVvk
#MedSky #NeuroSky #Ophthalmology
#MedSky #NeuroSky #Ophthalmology
October 13, 2025 at 4:44 PM
A new review explores current ideas about the disease, with emphasis on the importance of dural venous sinus stenosis and new treatment options. Read the full review: nej.md/3KJlVvk
#MedSky #NeuroSky #Ophthalmology
#MedSky #NeuroSky #Ophthalmology
Reposted by Raúl Pelayo
The newfound ensemble of neurons could lead to therapies to treat persistent pain
go.nature.com/4gZHzrv
go.nature.com/4gZHzrv
Brain area linked to chronic pain discovered — offering hope for treatments
The newfound ensemble of neurons could lead to therapies to treat persistent pain, which affects roughly one of five people globally.
go.nature.com
October 8, 2025 at 5:12 PM
The newfound ensemble of neurons could lead to therapies to treat persistent pain
go.nature.com/4gZHzrv
go.nature.com/4gZHzrv
Gracias a la #SEPC por invitarMe a explicar la actividad de neuromodulación que realizamos en el ámbito de la rehabilitación en @iguttmann.bsky.social @guttmannbcn.bsky.social
September 26, 2025 at 6:12 PM
Gracias a la #SEPC por invitarMe a explicar la actividad de neuromodulación que realizamos en el ámbito de la rehabilitación en @iguttmann.bsky.social @guttmannbcn.bsky.social
Effect of rTMS + RHB on Brain Functional Connectivity in #MS.
Poster #idi #ectrims2025 #rims2025 in BCN.
@iguttmann.bsky.social @cemcat-12em.bsky.social #idi @vallhebron.com @jaumesastregarriga.bsky.social @raulpelayo.bsky.social
Poster #idi #ectrims2025 #rims2025 in BCN.
@iguttmann.bsky.social @cemcat-12em.bsky.social #idi @vallhebron.com @jaumesastregarriga.bsky.social @raulpelayo.bsky.social
September 25, 2025 at 3:34 PM
Effect of rTMS + RHB on Brain Functional Connectivity in #MS.
Poster #idi #ectrims2025 #rims2025 in BCN.
@iguttmann.bsky.social @cemcat-12em.bsky.social #idi @vallhebron.com @jaumesastregarriga.bsky.social @raulpelayo.bsky.social
Poster #idi #ectrims2025 #rims2025 in BCN.
@iguttmann.bsky.social @cemcat-12em.bsky.social #idi @vallhebron.com @jaumesastregarriga.bsky.social @raulpelayo.bsky.social
Reposted by Raúl Pelayo
Beneficial impact of physical activity on multiple sclerosis disability progression jnnp.bmj.com/content/earl...
Beneficial impact of physical activity on multiple sclerosis disability progression
Background Physical activity has been associated with neuroprotective and immunomodulatory benefits, potentially influencing long-term disability outcomes in multiple sclerosis (MS). However, longitud...
jnnp.bmj.com
September 25, 2025 at 8:52 AM
Beneficial impact of physical activity on multiple sclerosis disability progression jnnp.bmj.com/content/earl...
Reposted by Raúl Pelayo
ICYMI: New online! Non-invasive brain stimulation: current and future applications in neurology
Non-invasive brain stimulation: current and future applications in neurology
Nature Reviews Neurology, Published online: 16 September 2025; doi:10.1038/s41582-025-01137-zNon-invasive brain stimulation (NIBS) shows considerable promise as a therapeutic strategy for neurological and psychiatric disorders. This Review explores the role of NIBS techniques, including repetitive transcranial magnetic stimulation and transcranial electrical stimulation, for treating cognitive impairments, speech and language difficulties, and motor control deficits in people with neurodegenerative or brain lesion disorders.
bit.ly
September 23, 2025 at 7:52 AM
ICYMI: New online! Non-invasive brain stimulation: current and future applications in neurology
Reposted by Raúl Pelayo
Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein
go.nature.com/4n8UwRQ
go.nature.com/4n8UwRQ
Years of hits to the head prime the brain for decline
Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein.
go.nature.com
September 18, 2025 at 10:33 AM
Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein
go.nature.com/4n8UwRQ
go.nature.com/4n8UwRQ