Olu Ajilore, MD, PhD
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pshrink.bsky.social
Olu Ajilore, MD, PhD
@pshrink.bsky.social
2.5K followers 1K following 110 posts
Psychiatrist and neuroscientist.

Computational Neuroimaging
Digital Mental Health
House Music

Co-Director of the CoNeCT Lab @ UIC
Posts Replies Media Videos
Reposted by Olu Ajilore, MD, PhD
grc-frontal-cortex.bsky.social
We are thrilled to announce that the preliminary program for the 2026 GRC on the Frontal Cortex is now live!
www.grc.org/frontal-cort...
Registration is now open for both the GRC and our GRS, chaired by @albitc.bsky.social and @jorge-miranda.bsky.social!
2026 Frontal Cortex Conference GRC
The 2026 Gordon Research Conference on Frontal Cortex will be held in Holderness, New Hampshire. Apply today to reserve your spot.
www.grc.org
November 18, 2025 at 3:15 PM
Reposted by Olu Ajilore, MD, PhD
storiesofwin.bsky.social
Thank you to all who joined us for our first in-person event! 💜 We hope you left feeling inspired and empowered!

#WomenInNeuroscience #StoriesOfWiN #SFN2025
November 15, 2025 at 10:19 PM
Reposted by Olu Ajilore, MD, PhD
jenna-m-norton.bsky.social
Can confirm. I am okay and more motivated than ever to speak up.

Nothing scares this administration more. Their power lies in our silence.
maxkozlov.bsky.social Max Kozlov @maxkozlov.bsky.social · 5d
NIH program officer @jenna-m-norton.bsky.social has been placed on admin leave, sources say.

Norton has been outspoken about the Trump administration's dismantling of science, and she signed the Bethesda Declaration.

Bhattacharya has said that "science is dead without free speech".
November 14, 2025 at 2:37 AM
Reposted by Olu Ajilore, MD, PhD
goldenneurons.bsky.social
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41...

#blueprint 1/7
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
www.nature.com
November 11, 2025 at 2:41 PM
Reposted by Olu Ajilore, MD, PhD
leadcoalition.bsky.social
Neurometabolic and vascular dysfunction as an early diagnostic for Alzheimer's disease and related dementias alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

#Alzheimers #dementia #science #neuroscience #NeuroSkyence
Neurovascular and metabolic changes across the AD spectrum, MVD pattern, and polar coordinates representation. A, The normal metabolic state continuum in healthy individuals is depicted by the black line. In contrast, the metabolic state across AD is represented by the orange line, illustrating the metabolic alterations observed throughout the disease's various phases, as proposed by the metabolic reprogramming theory. The red line represents the progression of perfusion across the disease, demonstrating how metabolism and perfusion become dysregulated until they eventually fail. During the hypermetabolic phase of the disease, oxidative phosphorylation undergoes upregulation as a compensatory response, leading to progressively oxidative damage. Furthermore, it is suggested that astrocytosis signaling precedes the onset of cognitive decline. B, Neurovascular and metabolic dysregulation were assessed by projecting the z score SUVR for each brain region onto Cartesian space. The x axis represents the z score changes in cerebral perfusion derived from CBF maps, while the y axis represents the z score change in glucose uptake derived from FDG. Brain regions toward the center of the plane are likely functioning at a normal level. A brain region is considered coupled if both signals are in the same direction (Cartesian quadrants 1 and 3) and uncoupled if they are opposite (Cartesian quadrants 2 and 4). We hypothesize the existence of a regional disease pathway (MVD pattern) that maps the disease progression and can accurately discern the MVD changes, which is: Type 1 Uncoupling → Type 2 Uncoupling → Prodromal → Neurometabolic-vascular Failure. C, Alternatively, Cartesian space readouts can be transformed into polar coordinates to visualize disease progression while preserving the MVD state. The distance from the origin represents the magnitude of the change, while the angle indicates the deviation of the change.
November 9, 2025 at 12:59 AM
Reposted by Olu Ajilore, MD, PhD
moryan.bsky.social
Please share: Lists of food resources in Chicago area. (Pls donate time or money to these places only if you can spare either; I know many can't.) Food resource links via GCFD www.chicagosfoodbank.org plus Rep Quigley's list of food banks in various communities: quigley.house.gov/sites/evo-su...
Food Depository in Chicago | Greater Chicago Food Depository
Hunger affects communities throughout Chicago and Cook County and we’re working to put an end to it. Get help or take action to support our efforts.
www.chicagosfoodbank.org
November 8, 2025 at 6:56 PM
Reposted by Olu Ajilore, MD, PhD
filmfreakmafia.mastodon.social.ap.brid.gy
'The Pitt' Has Inspired More Organ Donation and End-of-Life Planning | Michael Schneider for Variety (@Variety)
https://variety.com/2025/tv/news/the-pitt-organ-donation-end-of-life-planning-study-1236562186/
‘The Pitt’ Has Inspired More Organ Donation and End-of-Life Planning, According to USC Norman Lear Center Study
After just one season, Emmy-winning drama “The Pitt” is already having an impact on healthcare conversations. That’s the finding from a new study released Monday by the USC Norman Lear Center, which said “The Pitt” has shifted the conversation on issues such as organ donation and end-of-life planning. According to a group of 1,409 viewers […]
variety.com
November 2, 2025 at 8:41 PM
Reposted by Olu Ajilore, MD, PhD
mikeholloway.bsky.social
🧪 #resistrfk #defendresearch #standupforscience #RFKJr #Vaccines #HHS #CDC #antivax
75% of scientists considering emigrating. Many already have. "The science world is kinda ending."

www.youtube.com/watch?v=yLvO...
Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'
YouTube video by PBS NewsHour
www.youtube.com
October 30, 2025 at 12:11 AM
pshrink.bsky.social
5 year streak complete!
Screenshot of the NY Times Crossword app showing an 1825 day streak
October 30, 2025 at 4:19 AM
pshrink.bsky.social
Typing patterns on smartphones offer clues to cognitive health, new research suggests www.psypost.org/typing-patte...
Typing patterns on smartphones offer clues to cognitive health, new research suggests
Everyday smartphone use may reveal more about the brain than previously thought. Researchers found that slower typing speeds were linked to poorer cognitive performance, suggesting that phone keystrok...
www.psypost.org
October 21, 2025 at 5:23 PM
Reposted by Olu Ajilore, MD, PhD
acnporg.bsky.social
Apply TODAY for the ACNP Early-Stage Investigator Assistance Program! ACNP 64th Annual Meeting: Jan. 12-15, 2026, Atlantis Paradise Island Resort. You must already have an in-person invite or be registered to attend the meeting in person to apply. tinyurl.com/ctck8yjn 🌴
October 16, 2025 at 1:00 PM
Reposted by Olu Ajilore, MD, PhD
caterinagratton.bsky.social
Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
🧵👇
Dense Phenotyping of Human Brain Network Organization Using Precision fMRI
The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...
go.illinois.edu
October 16, 2025 at 3:00 PM
Reposted by Olu Ajilore, MD, PhD
bmj.com
The Trump administration and its allies have taken several steps to ensure that medical schools in the US dismantle all diversity, equity, and inclusion policies.

It is patients who will be the victims of this, write @gavinyamey.bsky.social and @michaeldgreen.com
www.bmj.com/content/391/...
October 10, 2025 at 5:13 PM
Reposted by Olu Ajilore, MD, PhD
petebuttigieg.bsky.social
Fewer than 1 in 10 of our Congressional races are considered competitive - in a country that's politically more or less 50-50.

This is madness. And it doesn't have to be this way.
October 10, 2025 at 8:26 PM
Reposted by Olu Ajilore, MD, PhD
nicolecrust.bsky.social
Please spread the word! I am recruiting a PhD student this cycle (Fall 2026 start) to join my team in a new venture: the neuroscience of mood.

If you are curious to learn more, this short talk provides a good overview of why, what and how.

www.youtube.com/watch?v=gjIK...
Nicole Rust - The representation of mood in the primate insula (May 6, 2025)
YouTube video by Simons Foundation
www.youtube.com
October 7, 2025 at 9:06 PM
Reposted by Olu Ajilore, MD, PhD
zenbrainest.bsky.social
www.nature.com/articles/s41...
Finally out!!
Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation - Translational Psychiatry
Translational Psychiatry - Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation
www.nature.com
October 7, 2025 at 9:14 PM
Reposted by Olu Ajilore, MD, PhD
jeremymberg.bsky.social
I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events.

Deafening Quiet from the Scientific Establishment

jeremymberg.github.io/jeremyberg.g...

1/14
jeremymberg.github.io
October 6, 2025 at 11:28 PM
Reposted by Olu Ajilore, MD, PhD
ccrosenphd.bsky.social
Hearing voices and other altered perceptual experiences across psychotic, mood, and anxiety disorders: from phenomenology and mechanisms to future directions
www.nature.com/articles/s41...
Hearing voices and other altered perceptual experiences across psychotic, mood, and anxiety disorders: from phenomenology and mechanisms to future directions - Schizophrenia
Schizophrenia - Hearing voices and other altered perceptual experiences across psychotic, mood, and anxiety disorders: from phenomenology and mechanisms to future directions
www.nature.com
October 1, 2025 at 10:49 PM
Reposted by Olu Ajilore, MD, PhD
jeremymberg.bsky.social
If you want a palate cleanser after yesterday’s autism discussion, listening to Kevin Mitchell is a good place to start…
wiringthebrain.bsky.social Kevin Mitchell @wiringthebrain.bsky.social · Jun 27
Free Will, Genetics, Autism, and What Makes You... You w/ Dr. Kevin Mitchell youtu.be/ntWpH97LXog?... via @YouTube - I really enjoyed this chat with Michael Cecchin, especially the chance to present the positive evidence for what really causes autism
Free Will, Genetics, Autism, and What Makes You... You w/ Dr. Kevin Mitchell
YouTube video by KNOW MORE KNOW LESS
youtu.be
September 23, 2025 at 10:05 AM
Reposted by Olu Ajilore, MD, PhD
goliashf.bsky.social
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉

📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
September 22, 2025 at 9:51 PM
Reposted by Olu Ajilore, MD, PhD
senguptalab.bsky.social
A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails.
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!
September 15, 2025 at 8:17 PM
Reposted by Olu Ajilore, MD, PhD
karaswisher.bsky.social
No notes
August 29, 2025 at 2:14 PM
Reposted by Olu Ajilore, MD, PhD
lluaces.bsky.social
1: This is a really cool study I was excited to be a part of! I was skeptical that brief unguided single session interventions could be effective in adults with depression as we had two studies in which we found minuscule effects vs weak controls (waiting), one in a large sample, N=828. I was wrong!
benji700.bsky.social Benji Kaveladze @benji700.bsky.social · Aug 26
New preprint! A Crowdsourced Megastudy of 12 Digital Single-Session Interventions for Depression in American Adults

What's the best way to help someone overcome depression with just 10 minutes of their time online? We ran a trial (n=7,505) testing 12 diverse interventions.

osf.io/preprints/ps...
August 26, 2025 at 8:08 PM
pshrink.bsky.social
I missed the big Alaskan press conference
a close up of a sign that says al
ALT: a close up of a sign that says al
media.tenor.com
August 15, 2025 at 11:35 PM