L Li
@promiselab.bsky.social
Proteome-level Microbial Systems Ecology (ProMiSE) Lab
Reposted by L Li
Serum N-glycoproteomics characterization of differential N-glycosylation in schizophrenia #JProteomics #MassSpec www.sciencedirect.com/science/arti...
Serum N-glycoproteomics characterization of differential N-glycosylation in schizophrenia
Glycosylation plays a crucial role in neurotransmission and signaling in schizophrenia; however, comprehensive characterization at the glycoproteome l…
www.sciencedirect.com
March 20, 2025 at 7:54 PM
Serum N-glycoproteomics characterization of differential N-glycosylation in schizophrenia #JProteomics #MassSpec www.sciencedirect.com/science/arti...
Reposted by L Li
The microbiologist's guide to metaproteomics
onlinelibrary.wiley.com/doi/full/10.... #Bioinformatics #microbiome #metaproteomics #proteomics #MS
onlinelibrary.wiley.com/doi/full/10.... #Bioinformatics #microbiome #metaproteomics #proteomics #MS
The microbiologist's guide to metaproteomics
Metaproteomics within the multi-omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs),...
onlinelibrary.wiley.com
May 8, 2025 at 2:03 PM
The microbiologist's guide to metaproteomics
onlinelibrary.wiley.com/doi/full/10.... #Bioinformatics #microbiome #metaproteomics #proteomics #MS
onlinelibrary.wiley.com/doi/full/10.... #Bioinformatics #microbiome #metaproteomics #proteomics #MS
Are you new to #metaproteomics but don't know where to start? Then this guide, written by experts of the Metaproteomics Initiative, is for you! onlinelibrary.wiley.com/doi/full/10....
The microbiologist's guide to metaproteomics
Metaproteomics within the multi-omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs),...
onlinelibrary.wiley.com
May 8, 2025 at 3:47 AM
Are you new to #metaproteomics but don't know where to start? Then this guide, written by experts of the Metaproteomics Initiative, is for you! onlinelibrary.wiley.com/doi/full/10....
Reposted by L Li
🚀 Interested in the interactions of xenobiotics with the gut microbiome? Join us @quadraminstitute.bsky.social to apply precision microbiome assays to xenobiotics. Apply by 28 May 2025. 👉 quadram.ac.uk/vacancies/gr...
#microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics
#microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics
Group Leader in Functional Microbiome Research - Quadram Institute
Applications are invited for a Group Leader in Functional Microbiome Research to join the laboratory of Professor Daniel Figeys at Quadram Institute Bioscience (QIB), based in Norwich, UK. Background:...
quadram.ac.uk
May 4, 2025 at 8:22 PM
🚀 Interested in the interactions of xenobiotics with the gut microbiome? Join us @quadraminstitute.bsky.social to apply precision microbiome assays to xenobiotics. Apply by 28 May 2025. 👉 quadram.ac.uk/vacancies/gr...
#microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics
#microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics
The oral microbiome is linked to various inflammatory conditions, including IBD. However, analyzing functional changes at the protein level has been challenging due to host protein interference. 🧵 1/3
I couldn’t be prouder—this is the work of the very first master's student that I've supervised. Salivary metaproteomics is tricky due to host/debris interference. Yuan et al. developed a microbial cell enrichment step and achieved cleaner data with better insights. www.nature.com/articles/s41...
OSaMPle workflow for salivary metaproteomics analysis reveals dysbiosis in inflammatory bowel disease patients - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - OSaMPle workflow for salivary metaproteomics analysis reveals dysbiosis in inflammatory bowel disease patients
www.nature.com
April 28, 2025 at 9:04 AM
The oral microbiome is linked to various inflammatory conditions, including IBD. However, analyzing functional changes at the protein level has been challenging due to host protein interference. 🧵 1/3
I couldn’t be prouder—this is the work of the very first master's student that I've supervised. Salivary metaproteomics is tricky due to host/debris interference. Yuan et al. developed a microbial cell enrichment step and achieved cleaner data with better insights. www.nature.com/articles/s41...
OSaMPle workflow for salivary metaproteomics analysis reveals dysbiosis in inflammatory bowel disease patients - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - OSaMPle workflow for salivary metaproteomics analysis reveals dysbiosis in inflammatory bowel disease patients
www.nature.com
April 24, 2025 at 12:01 PM
I couldn’t be prouder—this is the work of the very first master's student that I've supervised. Salivary metaproteomics is tricky due to host/debris interference. Yuan et al. developed a microbial cell enrichment step and achieved cleaner data with better insights. www.nature.com/articles/s41...
Metaproteomics deserves a dedicated β-diversity metric:
microbiolly.wordpress.com/2025/03/19/p...
microbiolly.wordpress.com/2025/03/19/p...
Metaproteomics deserves a dedicated β-diversity metric
Introducing PhyloFunc: A Phylogeny-Informed Functional Beta-Diversity Metric for Metaproteomics Metaproteomics deserves a dedicated β-diversity metric In microbiome research, comparing functional p…
microbiolly.wordpress.com
March 20, 2025 at 6:07 AM
Metaproteomics deserves a dedicated β-diversity metric:
microbiolly.wordpress.com/2025/03/19/p...
microbiolly.wordpress.com/2025/03/19/p...
Reposted by L Li
🚨 We mapped 4.6M #microbial protein responses to 312 compounds, uncovering 3 distinct functional gut #microbiome states and revealing how neuropharma triggers deep shifts (lower functional redundancy, higher #AMR proteins).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Systematic Metaproteomics Mapping Reveals Functional and Ecological Landscapes of Human Gut Microbiota Responses to Therapeutic Drugs
Therapeutic compounds significantly alter the composition of the gut microbiota, yet their functional and ecological impacts, particularly at the protein level, remain largely unexplored. In this stud...
www.biorxiv.org
February 15, 2025 at 2:04 PM
🚨 We mapped 4.6M #microbial protein responses to 312 compounds, uncovering 3 distinct functional gut #microbiome states and revealing how neuropharma triggers deep shifts (lower functional redundancy, higher #AMR proteins).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
🦠 In #metaproteomics, proteins are often treated as independent features, ignoring their ecological relationships.
🌱 We developed PhyloFunc, a beta diversity metric that integrates phylogeny into functional distance calculations, offering a more ecologically meaningful way to compare microbiomes.
🌱 We developed PhyloFunc, a beta diversity metric that integrates phylogeny into functional distance calculations, offering a more ecologically meaningful way to compare microbiomes.
PhyloFunc: phylogeny-informed functional distance as a new ecological metric for metaproteomic data analysis - Microbiome
Background Beta-diversity is a fundamental ecological metric for exploring dissimilarities between microbial communities. On the functional dimension, metaproteomics data can be used to quantify beta-...
microbiomejournal.biomedcentral.com
February 12, 2025 at 2:44 AM
🦠 In #metaproteomics, proteins are often treated as independent features, ignoring their ecological relationships.
🌱 We developed PhyloFunc, a beta diversity metric that integrates phylogeny into functional distance calculations, offering a more ecologically meaningful way to compare microbiomes.
🌱 We developed PhyloFunc, a beta diversity metric that integrates phylogeny into functional distance calculations, offering a more ecologically meaningful way to compare microbiomes.
🎉 Excited to share this amazing Metaproteomics Initiative community effort aims to make metaproteomics accessible and easy to use for microbiome researchers. Grateful for this unforgettable journey of collaboration! 🌍🔬 #Metaproteomics #Collaboration #Science chemrxiv.org/engage/chemr...
The Microbiologist’s Guide to Metaproteomics
Metaproteomics is an emerging approach for studying microbiomes, offering the ability to characterize proteins that underpin microbial functionality within diverse ecosystems. As the primary catalytic...
chemrxiv.org
January 12, 2025 at 6:49 AM
🎉 Excited to share this amazing Metaproteomics Initiative community effort aims to make metaproteomics accessible and easy to use for microbiome researchers. Grateful for this unforgettable journey of collaboration! 🌍🔬 #Metaproteomics #Collaboration #Science chemrxiv.org/engage/chemr...
Reposted by L Li
If you want to get started with #metaproteomics , this guide is a good starting point. This was an amazing metaproteomics community effort to get all the key information together led by Tim Van Den Bossche and Leyuan Li
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
The Microbiologist’s Guide to Metaproteomics
Metaproteomics is an emerging approach for studying microbiomes, offering the ability to characterize proteins that underpin microbial functionality within diverse ecosystems. As the primary catalytic...
chemrxiv.org
January 10, 2025 at 3:11 PM
If you want to get started with #metaproteomics , this guide is a good starting point. This was an amazing metaproteomics community effort to get all the key information together led by Tim Van Den Bossche and Leyuan Li
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...