Daniel Figeys
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dfigeys.bsky.social
Daniel Figeys
@dfigeys.bsky.social
360 followers 700 following 30 posts
Precision-function-based microbiome trials.
Ex vivo microbiome assays.
Microbiome–xenobiotic interactions.
Meta-omics analyses
Posts Replies Media Videos
Reposted by Daniel Figeys
quadraminstitute.bsky.social
⏰ Closing soon! We are looking for a Group Leader with a focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme as a Group Leader.

💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
A photo of the Quadram Institute building with the text "Group Leader, with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity. Salary: Competitive, Contract length: Indefinite, Apply by 18 January 2026."
January 11, 2026 at 5:05 PM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction.

💷 £45,450 to £56,750
🗓️ Apply by 15 February 2026
➡️ buff.ly/UpcuEPa
A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: £45,450 to £56,750, Contract length: 2 years, Apply by 15 February 2026."
January 7, 2026 at 2:30 PM
dfigeys.bsky.social
Are you interested in #metaproteomics? We have a senior scientist position in my lab focused on metaproteomics, and xenobiotic- #microbiome -host interactions. Check it out.
jobs.quadram.ac.uk/Details.asp?...
Quadram Institute
jobs.quadram.ac.uk
January 6, 2026 at 12:43 PM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
Researchers from the Quadram Institute have come together to develop a new open access book filled with cutting-edge methods and protocols to ensure best practice in microbiome research.
New book shares Quadram’s Best Practice in Microbiome Research - Quadram Institute
Researchers from the Quadram Institute have developed an open access book to help ensure best practice in microbiome research.
buff.ly
January 4, 2026 at 12:00 PM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
Our latest newsletter is out now 📩

Sign up to stay up to get our latest news straight to your inbox ⤵️
Newsletter - Quadram Institute
Our newsletter highlights the latest news and research breakthrough from across the Quadram Institute
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December 20, 2025 at 12:00 PM
dfigeys.bsky.social
Zhang et al, with the #RapidAIM assay and #metaproteomics, show that gut #microbiomes exhibit shared and individualized functional responses when exposed to six structurally distinct oligosaccharides. Functional understanding requires studying in dividual microbiome.
www.nature.com/articles/s41...
Microbiome-dependent functional responses to structurally distinct oligosaccharides revealed by metaproteomics - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Microbiome-dependent functional responses to structurally distinct oligosaccharides revealed by metaproteomics
www.nature.com
December 11, 2025 at 8:28 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
“The Quadram Institute is proud to be part of the newly launched National Research Organisations (NRO) Group – uniting UK research centres to #MakingResearchMatter for people, communities & the economy."

💬 Professor @dfigeys.bsky.social
nro-group.bsky.social NRO Group @nro-group.bsky.social · Dec 10
We’ve launched! 🎉 The National Research Organisations (NRO) Group unites 35 UK research organisations to provide a unified and authoritative perspective on science, policy, and research investment. Learn more: nrogroup.org #MakingResearchMatter #NROGroup
December 10, 2025 at 11:44 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
🆕 Anti-depressant drugs cause profound changes to the human gut microbiome, but these changes could be mitigated by prebiotics, according to a major new survey of how the microbial community in the gut responds to different therapeutic drugs 💊

@dfigeys.bsky.social
buff.ly/uKd5PDv
Prebiotics reverse effects of anti-depressants on the gut microbiome - Quadram Institute
Scientists from the University of Ottawa and Beijing Institute of Lifeomics found that SSRIs, SNRIs and Tricyclic Antidepressants, commonly prescribed anti-depressants that target the…
buff.ly
November 20, 2025 at 12:15 PM
Reposted by Daniel Figeys
ribozyme.bsky.social
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism www.cell.com/neuron/fullt...
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism
Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...
www.cell.com
November 15, 2025 at 5:15 PM
dfigeys.bsky.social
Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes.
@quadraminstitute.bsky.social
October 29, 2025 at 10:22 AM
dfigeys.bsky.social
Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins.
@quadraminstitute.bsky.social
dfigeys.bsky.social Daniel Figeys @dfigeys.bsky.social · Oct 26
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.

rdcu.be/eMmcT
October 27, 2025 at 7:32 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring 📉

Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood 🍅

➡️ buff.ly/SIsELo6
A landscape shot of the rooftops of Norwich, with the Cathedral in the centre. In the foreground are trees without their leaves.
October 26, 2025 at 4:03 PM
dfigeys.bsky.social
From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too.

rdcu.be/eMmcT
October 26, 2025 at 7:09 AM
dfigeys.bsky.social
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social

rdcu.be/eMmcT
Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs
Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...
rdcu.be
October 24, 2025 at 4:20 PM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
We were delighted to welcome Sir Ian Chapman the new CEO of @ukri.org , together with BBSRC representatives, to Norwich Research Park today hear about our world leading bioscience.

Discover more about our research at the Quadram Institute
➡️ buff.ly/NZYHB2r
October 23, 2025 at 4:15 PM
Reposted by Daniel Figeys
erictopol.bsky.social
Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...
Exposure to sugar rationing in first 1000 days after conception and long term cardiovascular outcomes: natural experiment study
Objective To examine whether exposure to sugar rationing during early life is associated with a reduction in the risk of cardiovascular outcomes in adulthood. Design Natural experiment study. Settin...
www.bmj.com
October 23, 2025 at 12:44 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
“This study is particularly important to me as it took place during my post doc years at the @uniofeastanglia.bsky.social and it has been a source of inspiration for my current research line, as a newly appointed Early Career Fellow at the Quadram Institute."

💬 Dr Serena Monaco
New technique to speed up the design of drugs targeting proteins in the cell membrane - Quadram Institute
An team has developed a new technique that will speed up the design of drugs targeting ion channels, a type of cell membrane protein
buff.ly
October 2, 2025 at 8:37 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
“Vitamin D deficiency represents a significant public health concern, especially during the winter months with significant deficiency across the UK population."

💬 Professor Martin Warren, our Chief Scientific Officer
Vitamin D3 concentrations are lowered by common vitamin D supplement - Quadram Institute
Taking vitamin D2 might be lowering the body's levels of the more efficient form of vitamin D, vitamin D3, according to new research
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September 22, 2025 at 8:11 AM
Reposted by Daniel Figeys
erlangen.bsky.social
Maternal emulsifier consumption alters the offspring microbiota leading to long-lasting diseases susceptibility
www.nature.com/articles/s41...
Consumption of food additives during pregnancy alters offspring gut microbiota and increases inflammatory disease risk
medicalxpress.com/news/2025-09...
Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibility - Nature Communications
Here, Delaroque et al. show that maternal intake of dietary emulsifiers alters offspring microbiota early in life, which, associated with perturbation of goblet cell function, promotes increased susce...
www.nature.com
September 22, 2025 at 1:54 AM
dfigeys.bsky.social
This is an exciting position that will shape the direction of how we target the gut microbiome. Come join my lab at the Quadram Institute.
quadraminstitute.bsky.social Quadram Institute @quadraminstitute.bsky.social · Sep 15
🆕 Vacancy! We're looking for a Senior Research Scientist to advance precision prebiotic microbiome intervention trials to study the interactions of prebiotics, drugs and other xenobiotics on the gut microbiome.

💷 £45,450 to £56,750
🗓️ Apply by 2 October 2025
➡️ buff.ly/BQKamDW
A social media card with a digital illustration of the gut microbiome and the text "Senior Research Scientist, to advance prevision prebiotic microbiome intervention trials and study the interactions of prebiotics, drugs and other xenobiotics"
September 17, 2025 at 10:07 AM
dfigeys.bsky.social
Interested in compound- microbiome interactions, and how they affect health? Join my lab at the Quadram Institute.
quadraminstitute.bsky.social Quadram Institute @quadraminstitute.bsky.social · Sep 15
🆕 Vacancy! We're looking for a Research Scientist (Xenobiotics) to investigate xenobiotic–microbiome interactions and understand the variation in responses across different individual microbiomes.

💷 £37,500 to £45,350
🗓️ Apply by 2 October 2025
➡️ buff.ly/8abEye5
A social card with an illustration of a molecules like forms, forming a person in part of the image, plus the text "Research Scientist (Xenobiotics) to investigate xenobiotic-microbiome interactions and understand variation across different individual microbiomes. Salary: £37,500 to £43,350, Contract length: 2.5 Years, Apply by 2 October 2025
September 16, 2025 at 9:57 AM
dfigeys.bsky.social
Interested in healthy aging and the microbiome? Join my lab to explore how ex vivo microbiome assays can guide personalized interventions that modulate specific microbiome-derived metabolites critical for health.
quadraminstitute.bsky.social Quadram Institute @quadraminstitute.bsky.social · Sep 16
🆕 Vacancy! We're looking for a Research Scientist (Clinical Microbiome) to advance precision prebiotic microbiome intervention trials aimed at promoting healthy ageing.

💷 £37,500 to £45,350
🗓️ Apply by 2 October 2025
➡️ buff.ly/KGl7eiG
A photo of someone pipetting in the lab and the text "Research Scientist (Clinical Microbiome) to advance precision prebiotic microbiome intervention trials aimed at promoting trials aimed at promoting healthy ageing, Salary: £37,500 to £43,350, Contract length: 2.5 years, Apply by 2 October"
September 16, 2025 at 9:52 AM
Reposted by Daniel Figeys
bugsinyourguts.bsky.social
If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities.

forms.office.com/pages/respon...
September 13, 2025 at 6:31 AM
Reposted by Daniel Figeys
quadraminstitute.bsky.social
🆕 Vacancy! We’re looking for a Chief Scientific Officer to support the development of the institute’s scientific strategy and scientific leadership of the institute.

💷 Competitive
🗓️ Apply by 12 October 2025
➡️ buff.ly/mKUhD3K
A social card with an image of the Quadram Institute labs and the sentence "To support the development of the institute's scientific strategy and scientific leadership of the institute. Salary: Competitive, Contract length: indefinite, apply by 12 October 2025
September 12, 2025 at 2:00 PM
dfigeys.bsky.social
Thank you @microbiomevif.bsky.social for inviting me. Very insightful questions. Looking forward to follow up.
September 10, 2025 at 4:56 AM