Eurico Morais-de-Sá
@polarityi3s.bsky.social
Drosophilist & Biochemist interested in cell asymmetries.
Epithelial Polarity & Cell Division Lab
https://www.i3s.up.pt/research-group.php?groupid=123
Epithelial Polarity & Cell Division Lab
https://www.i3s.up.pt/research-group.php?groupid=123
Pinned
First official post! A new paper out about #cytokinesis in #epithelia
www.embopress.org/doi/full/10....
Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.
www.embopress.org/doi/full/10....
Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.
Reposted by Eurico Morais-de-Sá
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
November 12, 2025 at 5:42 PM
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
Reposted by Eurico Morais-de-Sá
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
Reposted by Eurico Morais-de-Sá
Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy
Protein phosphatase 1 (PP1) is essential for spindle assembly checkpoint (SAC) silencing and mitotic exit, but its regulation during mitosis remains i…
www.sciencedirect.com
October 23, 2025 at 7:14 AM
Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Eurico Morais-de-Sá
Interested in cell migration and developmental biology-check out this PhD opportunity!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
October 10, 2025 at 4:30 PM
Interested in cell migration and developmental biology-check out this PhD opportunity!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Eurico Morais-de-Sá
So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
September 30, 2025 at 2:29 PM
So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Eurico Morais-de-Sá
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
October 1, 2025 at 6:21 PM
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Reposted by Eurico Morais-de-Sá
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
September 22, 2025 at 9:37 AM
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
Reposted by Eurico Morais-de-Sá
How can we use cell shapes and geometry to study mechanics of tissues?
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
September 13, 2025 at 7:15 AM
How can we use cell shapes and geometry to study mechanics of tissues?
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics
Reposted by Eurico Morais-de-Sá
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
September 3, 2025 at 2:15 PM
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...
#Reproducibility
#Reproducibility
Reposted by Eurico Morais-de-Sá
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN
rdcu.be/etKdN
Advancing cancer research via comparative oncology
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
rdcu.be
June 30, 2025 at 4:27 PM
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN
rdcu.be/etKdN
Reposted by Eurico Morais-de-Sá
Epithelial morphogenesis is all about how epithelial tissues develop unique shapes and structures! I'm @nehaghosh.bsky.social and will share some research in this area.
June 29, 2025 at 6:44 AM
Epithelial morphogenesis is all about how epithelial tissues develop unique shapes and structures! I'm @nehaghosh.bsky.social and will share some research in this area.
Reposted by Eurico Morais-de-Sá
A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation: Cell
1/2
www.cell.com/cell/abstrac...
1/2
www.cell.com/cell/abstrac...
A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation
This work introduces Flysta3D-v2, a 3D spatiotemporal multi-omics database that spans
Drosophila development from embryogenesis to metamorphosis. Through the integration
of multimodal data, we detail ...
www.cell.com
June 28, 2025 at 5:57 AM
A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation: Cell
1/2
www.cell.com/cell/abstrac...
1/2
www.cell.com/cell/abstrac...
Reposted by Eurico Morais-de-Sá
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
June 18, 2025 at 7:06 PM
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
Reposted by Eurico Morais-de-Sá
extremely happy to present the final version of our "smurf mice" paper www.biorxiv.org/content/10.1..., led by Céline Cansell when she was a postdoc in my group (now an independent @inrae-france.bsky.social researcher).
Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process
Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process
June 19, 2025 at 5:06 PM
extremely happy to present the final version of our "smurf mice" paper www.biorxiv.org/content/10.1..., led by Céline Cansell when she was a postdoc in my group (now an independent @inrae-france.bsky.social researcher).
Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process
Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process
Reposted by Eurico Morais-de-Sá
A reminder in these hard times. #sciencestrong
February 19, 2025 at 6:14 AM
A reminder in these hard times. #sciencestrong
Reposted by Eurico Morais-de-Sá
My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...
Interphase cell morphology defines the mode, symmetry, and outcome of mitosis
During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...
www.science.org
May 6, 2025 at 8:39 PM
My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...
Reposted by Eurico Morais-de-Sá
#EDRC2025 👇🏻👇🏻👇🏻👇🏻
Remember to get your #EDRC2025 workshop proposal in before the 5th of May!
📣The #EDRC2025 will select proposals for six workshops, each with up to nine speakers (12 minutes presentations + 3 minutes Q/A). If you are interested in hosting a workshop, please send a one-page proposal to edrc2025alicante@umh.es by May 5, 2025 🧪🪰
April 29, 2025 at 4:12 PM
#EDRC2025 👇🏻👇🏻👇🏻👇🏻
Reposted by Eurico Morais-de-Sá
Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!
April 25, 2025 at 2:08 PM
Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!
Reposted by Eurico Morais-de-Sá
#CellMigration 𝐢𝐧 𝐯𝐢𝐯𝐨!
Excited to share this video on #FluorescenceFriday 🌈
Today as a GIF to circumvent video compression 😅!
Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social)
#cellbio #sciart #devbio #science #microscopy
Excited to share this video on #FluorescenceFriday 🌈
Today as a GIF to circumvent video compression 😅!
Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social)
#cellbio #sciart #devbio #science #microscopy
April 25, 2025 at 12:25 PM
#CellMigration 𝐢𝐧 𝐯𝐢𝐯𝐨!
Excited to share this video on #FluorescenceFriday 🌈
Today as a GIF to circumvent video compression 😅!
Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social)
#cellbio #sciart #devbio #science #microscopy
Excited to share this video on #FluorescenceFriday 🌈
Today as a GIF to circumvent video compression 😅!
Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social)
#cellbio #sciart #devbio #science #microscopy
Reposted by Eurico Morais-de-Sá
Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost
www.grc.org/cell-contact...
www.grc.org/cell-contact...
December 18, 2024 at 3:43 PM
Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost
www.grc.org/cell-contact...
www.grc.org/cell-contact...
Reposted by Eurico Morais-de-Sá
1/14 “Epithelial” & “Mesenchymal” aren’t binary categories—they form a spectrum, or better yet, a multidimensional space. This becomes especially clear in collective cell migration, which often depends on a finely tuned degree of “mesenchymal-ness”.
#cellbio #devbio #cellmigration
#cellbio #devbio #cellmigration
April 20, 2025 at 7:32 AM
1/14 “Epithelial” & “Mesenchymal” aren’t binary categories—they form a spectrum, or better yet, a multidimensional space. This becomes especially clear in collective cell migration, which often depends on a finely tuned degree of “mesenchymal-ness”.
#cellbio #devbio #cellmigration
#cellbio #devbio #cellmigration
Reposted by Eurico Morais-de-Sá
I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social
www.sciencedirect.com/science/arti...
It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.
www.sciencedirect.com/science/arti...
It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.
Proximity-based activation of AURORA A by MPS1 potentiates error correction
Faithful cell division relies on mitotic chromosomes becoming bioriented with each pair of sister kinetochores bound to microtubules oriented toward o…
www.sciencedirect.com
April 13, 2025 at 1:52 AM
I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social
www.sciencedirect.com/science/arti...
It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.
www.sciencedirect.com/science/arti...
It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.
Reposted by Eurico Morais-de-Sá
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
April 10, 2025 at 6:06 AM
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Reposted by Eurico Morais-de-Sá
Same for ZFIN! @zfinmod.bsky.social put them in your papers' acknowledgements and cite them (Bradford et al. 2022 academic.oup.com/genetics/art...)
April 10, 2025 at 6:24 AM
Same for ZFIN! @zfinmod.bsky.social put them in your papers' acknowledgements and cite them (Bradford et al. 2022 academic.oup.com/genetics/art...)
Reposted by Eurico Morais-de-Sá
We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 7, 2025 at 1:01 PM
We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology.
www.nature.com/articles/s41...
www.nature.com/articles/s41...