@bilderlab
@bilderlab.bsky.social
Epithelial biology: polarizing proteins, elongating eggs, and cold-blooded cancer
Reposted by @bilderlab
@bilderlab.bsky.social Karaoke night. Please clap for my charcuterie board.
October 24, 2025 at 10:15 AM
@bilderlab.bsky.social Karaoke night. Please clap for my charcuterie board.
Reposted by @bilderlab
FWIW we also find that flies show coagulopathy, another big cause of death of cancer patients pubmed.ncbi.nlm.nih.gov/37354901/
Systemic coagulopathy promotes host lethality in a new Drosophila tumor model - PubMed
Malignant tumors trigger a complex network of inflammatory and wound repair responses, prompting Dvorak's characterization of tumors as "wounds that never heal."<sup>1</sup> Some of these responses le...
pubmed.ncbi.nlm.nih.gov
October 18, 2025 at 2:45 PM
FWIW we also find that flies show coagulopathy, another big cause of death of cancer patients pubmed.ncbi.nlm.nih.gov/37354901/
Reposted by @bilderlab
Maybe referring to a 2015 paper from our lab? pubmed.ncbi.nlm.nih.gov/25850672/ @perrimonlab.bsky.social published back-to-back: pubmed.ncbi.nlm.nih.gov/25850671/.
Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting - PubMed
Tumors kill patients not only through well-characterized perturbations to their local environment but also through poorly understood pathophysiological interactions with distant tissues. Here, we use ...
pubmed.ncbi.nlm.nih.gov
October 18, 2025 at 2:29 PM
Maybe referring to a 2015 paper from our lab? pubmed.ncbi.nlm.nih.gov/25850672/ @perrimonlab.bsky.social published back-to-back: pubmed.ncbi.nlm.nih.gov/25850671/.
And so fabulous to dine out with former postdocs Anne Classen @classenlab.bsky.social, Thomas Vaccari @vaccarilab.bsky.social and Lucy O’Brien. Many laughs, fond memories, and talk of bright futures for all of them. #EDRC2025
September 29, 2025 at 8:44 PM
And so fabulous to dine out with former postdocs Anne Classen @classenlab.bsky.social, Thomas Vaccari @vaccarilab.bsky.social and Lucy O’Brien. Many laughs, fond memories, and talk of bright futures for all of them. #EDRC2025
Honored to share stage with all the great plenary speakers at #EDRC2025. Exciting science and great vibes from Drosophila researchers worldwide – Let’s keep the American, Euro, and APAC communities coordinated and strong!
September 29, 2025 at 8:39 PM
Honored to share stage with all the great plenary speakers at #EDRC2025. Exciting science and great vibes from Drosophila researchers worldwide – Let’s keep the American, Euro, and APAC communities coordinated and strong!
Beautiful paper from former student @dy-chen.bsky.social now postdoc in Zernicka-Goetz lab. Human embryos, stem cell models & mice: BM heterogeneity drives AP symmetry breaking. High-end microscopy, live imaging, physical modeling, mechanistic tests. Tour de force. www.nature.com/articles/s41...
Basement membrane perforations guide anterior–posterior axis formation - Nature Communications
Chen et al. show that in mice, extracellular matrix remodeling drives early migration of the anterior signaling center, establishing the body axis sooner than expected—a mechanism potentially conserve...
www.nature.com
August 8, 2025 at 3:32 AM
Beautiful paper from former student @dy-chen.bsky.social now postdoc in Zernicka-Goetz lab. Human embryos, stem cell models & mice: BM heterogeneity drives AP symmetry breaking. High-end microscopy, live imaging, physical modeling, mechanistic tests. Tour de force. www.nature.com/articles/s41...
Amazing and multitalented postdoc @ongkaty.bsky.social taking time out from writing her new paper with this generous initiative. #genetics, #CRISPR, #drosophila, hallmarks of #cancer and more. For a great cause; support @flybase.bsky.social!
All proceeds from my #sciart Etsy shop will now be donated to
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
July 10, 2025 at 4:40 AM
Amazing and multitalented postdoc @ongkaty.bsky.social taking time out from writing her new paper with this generous initiative. #genetics, #CRISPR, #drosophila, hallmarks of #cancer and more. For a great cause; support @flybase.bsky.social!
Reposted by @bilderlab
All proceeds from my #sciart Etsy shop will now be donated to
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
July 10, 2025 at 3:52 AM
All proceeds from my #sciart Etsy shop will now be donated to
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
@flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag!
www.etsy.com/shop/Picosti...
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN
rdcu.be/etKdN
Advancing cancer research via comparative oncology
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
rdcu.be
June 30, 2025 at 4:27 PM
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN
rdcu.be/etKdN
New paper from superb postdoc Hui-Yu Ku about how proteases pattern extracellular matrix to precisely sculpt an organ.
She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 13, 2025 at 8:14 PM
New paper from superb postdoc Hui-Yu Ku about how proteases pattern extracellular matrix to precisely sculpt an organ.
She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
Thursday, May 22 from 1 – 2:15 pm ET, Wu-Min Deng,
@perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
@perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
May 11, 2025 at 5:32 PM
Thursday, May 22 from 1 – 2:15 pm ET, Wu-Min Deng,
@perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
@perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
Reposted by @bilderlab
Congrats to MCB's Diana Bautista and David Bilder for being named as AAAS Fellows @aaas.org! @bilderlab.bsky.social 👏 🎉https://news.berkeley.edu/2025/03/27/seven-faculty-members-named-fellows-of-american-association-for-the-advancement-of-science/
March 31, 2025 at 5:11 PM
Congrats to MCB's Diana Bautista and David Bilder for being named as AAAS Fellows @aaas.org! @bilderlab.bsky.social 👏 🎉https://news.berkeley.edu/2025/03/27/seven-faculty-members-named-fellows-of-american-association-for-the-advancement-of-science/
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details.
(1/5)
(1/5)
February 25, 2025 at 7:25 PM
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details.
(1/5)
(1/5)
Reposted by @bilderlab
Citrus tasting at the annual @bilderlab.bsky.social Lunar New Year Party 🍊
February 25, 2025 at 4:25 PM
Citrus tasting at the annual @bilderlab.bsky.social Lunar New Year Party 🍊
Thursday, January 30 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Join to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
January 9, 2025 at 10:32 PM
Thursday, January 30 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Join to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
Part of our lab studies #Drosophila cancer models. Delighted to announce ‘Beyond Mammals: Exploring Cancer Models” webinar held by NCI, hopefully in advance of funding opportunities. I’m speaking with @perrimonlab.bsky.social and others incl #Zebrafish and #Celegans PIs. Registration free.
Beyond Mammals: Exploring Cancer Models Webinar Series (Overview) | Events Registration
Overview The Beyond Mammals: Exploring Cancer Models series will feature three webinars, each focused on one non-mammalian animal model and its applicability to cancer research. Each webinar will high...
events.cancer.gov
November 15, 2024 at 4:47 AM
Part of our lab studies #Drosophila cancer models. Delighted to announce ‘Beyond Mammals: Exploring Cancer Models” webinar held by NCI, hopefully in advance of funding opportunities. I’m speaking with @perrimonlab.bsky.social and others incl #Zebrafish and #Celegans PIs. Registration free.
Hosted a joint lab retreat with @LOBrienLab. Shared lots of science, some lore, and a bit of history, and introduced the Stanford folks to some of the joys of Berkeley.
March 25, 2024 at 10:57 PM
Hosted a joint lab retreat with @LOBrienLab. Shared lots of science, some lore, and a bit of history, and introduced the Stanford folks to some of the joys of Berkeley.
New lab preprint —longtime project finished in Hong Kong by new investigator @Jung_Kim_PhD.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 25, 2024 at 10:55 PM
New lab preprint —longtime project finished in Hong Kong by new investigator @Jung_Kim_PhD.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Now accepting applications- come join us in Berkeley!
#Drosophila #Celegans
careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
#Drosophila #Celegans
careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
We are hiring a research technician for June here in Berkeley.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
March 8, 2024 at 7:46 PM
Now accepting applications- come join us in Berkeley!
#Drosophila #Celegans
careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
#Drosophila #Celegans
careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
We are hiring a research technician for June here in Berkeley.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
February 26, 2024 at 4:47 PM
We are hiring a research technician for June here in Berkeley.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
Great for a post-bac interested in genetics, development or cancer biology.
bilderlab.berkeley.edu
Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila.
Please RT.
Reposted by @bilderlab
The Interactive Fly (www.sdbonline.org/sites/fly/ai...) is a guide to fruit fly development. It describes the literature of over 1,700 genes, dealing with developmental pathways and gene regulation. Sections include Drosophila as a model for human diseases, evolutionary biology, and neural circuits
November 20, 2023 at 12:54 AM
The Interactive Fly (www.sdbonline.org/sites/fly/ai...) is a guide to fruit fly development. It describes the literature of over 1,700 genes, dealing with developmental pathways and gene regulation. Sections include Drosophila as a model for human diseases, evolutionary biology, and neural circuits
Thomas Brodsky has arrived on Bluesky! Tom runs The Interactive Fly website and tirelessly surveys the #Drosophila literature. He won one of the inaugural Drosophila Community Service awards last year. Please follow him, like his posts, and welcome him here!
Prasad, D., Illek, K., Fischer, F., Holstein, K. and Classen, A. K. (2023). Bilateral JNK activation is a hallmark of interface surveillance and promotes elimination of aberrant cells. Elife 12. elifesciences.org/articles/80809
November 20, 2023 at 5:28 AM
Thomas Brodsky has arrived on Bluesky! Tom runs The Interactive Fly website and tirelessly surveys the #Drosophila literature. He won one of the inaugural Drosophila Community Service awards last year. Please follow him, like his posts, and welcome him here!
Nice @berkeleyMCB turnout tonight for @nkwhiteman.bsky.social 's triumphant talk about his book 'Most Delicious Poison'!
@gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab
n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social
Sabeeha Merchant
@gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab
n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social
Sabeeha Merchant
November 16, 2023 at 3:57 AM
Nice @berkeleyMCB turnout tonight for @nkwhiteman.bsky.social 's triumphant talk about his book 'Most Delicious Poison'!
@gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab
n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social
Sabeeha Merchant
@gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab
n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social
Sabeeha Merchant
October 31, 2023 at 3:09 PM