ꙮ Pavel Janoš ꙮ
@pjanos.bsky.social
Researcher at CNR-IOM c/o SISSA, Trieste, Italy.
MD, protein/RNA, drug design.
'I didn’t ask to be a multicellular organism.'
https://magistratogroup.wordpress.com/
MD, protein/RNA, drug design.
'I didn’t ask to be a multicellular organism.'
https://magistratogroup.wordpress.com/
Reposted by ꙮ Pavel Janoš ꙮ
📢 Save the Date!
We are thrilled to announce that the Congress of our Division will be held in Palermo.
🗓️ September 16-18, 2026.
See you next year in Sicily!
🛍️As always, scholarships will be available for young researchers.
The website will be available soon!
#DCSB2026
We are thrilled to announce that the Congress of our Division will be held in Palermo.
🗓️ September 16-18, 2026.
See you next year in Sicily!
🛍️As always, scholarships will be available for young researchers.
The website will be available soon!
#DCSB2026
October 16, 2025 at 6:58 PM
📢 Save the Date!
We are thrilled to announce that the Congress of our Division will be held in Palermo.
🗓️ September 16-18, 2026.
See you next year in Sicily!
🛍️As always, scholarships will be available for young researchers.
The website will be available soon!
#DCSB2026
We are thrilled to announce that the Congress of our Division will be held in Palermo.
🗓️ September 16-18, 2026.
See you next year in Sicily!
🛍️As always, scholarships will be available for young researchers.
The website will be available soon!
#DCSB2026
Reposted by ꙮ Pavel Janoš ꙮ
Just published: RNA G-quadruplex folding mechanism via all-atom simulations in collaboration with my former PhD lab. Many thanks to Petr, Jiří, Vojtěch, and the reviewers, who encouraged us to pursue folding the full human telomeric G4.
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
RNA G-quadruplexes emerge from a compacted coil-like ensemble via multiple pathways
Abstract. RNA G-quadruplexes (rG4s) are emerging as vital structural elements involved in processes like gene regulation, translation, and genome stability
academic.oup.com
September 10, 2025 at 7:30 AM
Just published: RNA G-quadruplex folding mechanism via all-atom simulations in collaboration with my former PhD lab. Many thanks to Petr, Jiří, Vojtěch, and the reviewers, who encouraged us to pursue folding the full human telomeric G4.
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
Reposted by ꙮ Pavel Janoš ꙮ
Our study is now published on JCIM🎉
We expanded and refined the preprint thanks to the insightful feedback from reviewers!
paper: pubs.acs.org/doi/10.1021/...
code: github.com/RitAreaScien...
We expanded and refined the preprint thanks to the insightful feedback from reviewers!
paper: pubs.acs.org/doi/10.1021/...
code: github.com/RitAreaScien...
Evolutionary Constraints Guide AlphaFold2 in Predicting Alternative Conformations and Inform Rational Mutation Design
Investigating structural variability is essential for understanding protein biological functions. Although AlphaFold2 accurately predicts static structures, it fails to capture the full spectrum of f...
pubs.acs.org
September 4, 2025 at 7:49 AM
Our study is now published on JCIM🎉
We expanded and refined the preprint thanks to the insightful feedback from reviewers!
paper: pubs.acs.org/doi/10.1021/...
code: github.com/RitAreaScien...
We expanded and refined the preprint thanks to the insightful feedback from reviewers!
paper: pubs.acs.org/doi/10.1021/...
code: github.com/RitAreaScien...
Reposted by ꙮ Pavel Janoš ꙮ
Almost at the end of the exciting @cecamevents.bsky.social conference 'RNA Modelling across scales' at SISSA, Trieste, Italy! 🎉 Fantastic speakers and great science. Organized with @bussigio.bsky.social @marcodevivo.bsky.social #RNA
May 21, 2025 at 7:22 PM
Almost at the end of the exciting @cecamevents.bsky.social conference 'RNA Modelling across scales' at SISSA, Trieste, Italy! 🎉 Fantastic speakers and great science. Organized with @bussigio.bsky.social @marcodevivo.bsky.social #RNA
Reposted by ꙮ Pavel Janoš ꙮ
Our integrative approach using #MD and #cryoEM data to construct structural ensembles of #RNA just published on @natcomms.bsky.social doi.org/10.1038/s414... Lead by Elisa Posani, with @magistratolab.bsky.social @bonomimax.bsky.social @pjanos.bsky.social @navtejtoor.bsky.social and Daniel Haack 🎉
May 16, 2025 at 9:16 AM
Our integrative approach using #MD and #cryoEM data to construct structural ensembles of #RNA just published on @natcomms.bsky.social doi.org/10.1038/s414... Lead by Elisa Posani, with @magistratolab.bsky.social @bonomimax.bsky.social @pjanos.bsky.social @navtejtoor.bsky.social and Daniel Haack 🎉
Reposted by ꙮ Pavel Janoš ꙮ
We are sill accepting applications for poster presentations at the CECAM conference 'RNA Modelling Across Scales". Join us in the beautiful Trieste ☀️🏖️🏰! Apply now: www.cecam.org/workshop-det... Co-organized with @bussigio.bsky.social @marcodevivo.bsky.social
March 27, 2025 at 7:04 PM
We are sill accepting applications for poster presentations at the CECAM conference 'RNA Modelling Across Scales". Join us in the beautiful Trieste ☀️🏖️🏰! Apply now: www.cecam.org/workshop-det... Co-organized with @bussigio.bsky.social @marcodevivo.bsky.social
Reposted by ꙮ Pavel Janoš ꙮ
Tohle je moc pěkná věc. 😍 Oblek, který vás zneviditelní před dronem vybaveným termokamerou. Zdokonalený a vyrobený v České republice. Chceme jich koupit 333 pro ukrajinské speciály. Na půlku vybíráme peníze a druhou zaplatí partneři z ColtCZ.
www.zbraneproukrajinu.cz/kampane/nevi...
www.zbraneproukrajinu.cz/kampane/nevi...
333 neviditelných obleků pro ukrajinské speciály - Dárek pro Putina
Nebýt viděn je základ každého úspěšného boje. Teď v době, kdy na frontě vládnou drony vybavené termokamerami, je to čím dál těžší. Ale není to nemožné. Chceme na frontu poslat 333 speciálních nevidite...
www.zbraneproukrajinu.cz
March 11, 2025 at 2:23 PM
Tohle je moc pěkná věc. 😍 Oblek, který vás zneviditelní před dronem vybaveným termokamerou. Zdokonalený a vyrobený v České republice. Chceme jich koupit 333 pro ukrajinské speciály. Na půlku vybíráme peníze a druhou zaplatí partneři z ColtCZ.
www.zbraneproukrajinu.cz/kampane/nevi...
www.zbraneproukrajinu.cz/kampane/nevi...
Reposted by ꙮ Pavel Janoš ꙮ
Interested in understanding the molecular details of RNA–membrane association? Read our new paper just published in Nano Letters @acs.org. Excellent work done by sdimarco.bsky.social with Jana Aupic and @bussigio.bsky.social pubs.acs.org/doi/full/10....
#RNA #MembraneBiology #compchem #compbiol
#RNA #MembraneBiology #compchem #compbiol
All-Atom Simulations Elucidate the Molecular Mechanism Underlying RNA–Membrane Interactions
RNA–membrane interactions are starting to emerge as an important organizing force in both natural and synthetic biological systems. Notably, RNA molecules were recently discovered to be present on the...
pubs.acs.org
March 9, 2025 at 11:39 AM
Interested in understanding the molecular details of RNA–membrane association? Read our new paper just published in Nano Letters @acs.org. Excellent work done by sdimarco.bsky.social with Jana Aupic and @bussigio.bsky.social pubs.acs.org/doi/full/10....
#RNA #MembraneBiology #compchem #compbiol
#RNA #MembraneBiology #compchem #compbiol
Reposted by ꙮ Pavel Janoš ꙮ
Reposted by ꙮ Pavel Janoš ꙮ
Very proud to announce that a member of our group, Dr. Jana Aupič, has been awarded the prestigious "EuChemS ChemBioLife Young Investigator" prize! 🏅 This honors her hard work and exceptional contribution to chemical biology. Congratulations, Jana! 🌟✨ .
www.euchems.eu/divisions/ch...
www.euchems.eu/divisions/ch...
News - EuChemS
WINNER ANNOUNCEMENT! “EuChemS ChemBioLife Young Investigator Award” 2024-2025 edition We are proud to announce the winner of the EuChemS ChemBioLife Young Investigator Award of the EuChemS Division...
www.euchems.eu
February 4, 2025 at 4:03 PM
Very proud to announce that a member of our group, Dr. Jana Aupič, has been awarded the prestigious "EuChemS ChemBioLife Young Investigator" prize! 🏅 This honors her hard work and exceptional contribution to chemical biology. Congratulations, Jana! 🌟✨ .
www.euchems.eu/divisions/ch...
www.euchems.eu/divisions/ch...
Reposted by ꙮ Pavel Janoš ꙮ
Today, we honor the defenders of Donetsk Airport—our legendary Cyborgs. Ten years ago, under relentless shelling for 242 days, they stood their ground and showed the world the unbreakable strength of Ukraine.
January 20, 2025 at 10:10 AM
Today, we honor the defenders of Donetsk Airport—our legendary Cyborgs. Ten years ago, under relentless shelling for 242 days, they stood their ground and showed the world the unbreakable strength of Ukraine.
Reposted by ꙮ Pavel Janoš ꙮ
Just published in Journal of Chemical Information and Modeling our new study on the Mechanism of Rac1b: the Alternative Spliced Variant of Rac1 Small Rho GTPase. Great work by A. Parise and S. Cresca!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Assessing the Mechanism of Rac1b: An All-Atom Simulation Study of the Alternative Spliced Variant of Rac1 Small Rho GTPase
The Rho GTPase family plays a key role in cell migration, cytoskeletal dynamics, and intracellular signaling. Rac1 and its splice variant Rac1b, characterized by the insertion of an Extraloop, are fre...
pubs.acs.org
December 9, 2024 at 3:33 PM
Just published in Journal of Chemical Information and Modeling our new study on the Mechanism of Rac1b: the Alternative Spliced Variant of Rac1 Small Rho GTPase. Great work by A. Parise and S. Cresca!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by ꙮ Pavel Janoš ꙮ
Prague's Kafka International Named Most Alienating Airport
Prague's Kafka International Named Most Alienating Airport
YouTube video by The Onion
www.youtube.com
November 26, 2024 at 6:00 PM
Prague's Kafka International Named Most Alienating Airport