Pavlína Pokorná
pokorna.bsky.social
Pavlína Pokorná
@pokorna.bsky.social
hiker and computational structural biologist 🧬💻, postdoc at CNR-IOM SISSA
Reposted by Pavlína Pokorná
Our new review entitled 'Decoding Spliceosome Dynamics through Computation and Experiment' has been published on Chemical Reviews @pubs.acs.org Congrats to @pokorna.bsky.social, Sebastian Fica and Jana Aupic! pubs.acs.org/doi/10.1021/...
Decoding Spliceosome Dynamics through Computation and Experiment
RNA splicing is orchestrated by a complex and exceptionally dynamic RNA–protein machine, called the spliceosome. Stepwise, large-scale structural and compositional remodeling of the spliceosome enable...
pubs.acs.org
October 14, 2025 at 8:51 AM
Just published: RNA G-quadruplex folding mechanism via all-atom simulations in collaboration with my former PhD lab. Many thanks to Petr, Jiří, Vojtěch, and the reviewers, who encouraged us to pursue folding the full human telomeric G4.
academic.oup.com/nar/article-...
RNA G-quadruplexes emerge from a compacted coil-like ensemble via multiple pathways
Abstract. RNA G-quadruplexes (rG4s) are emerging as vital structural elements involved in processes like gene regulation, translation, and genome stability
academic.oup.com
September 10, 2025 at 7:30 AM