forterre
@pforterre.bsky.social
Reposted by forterre
Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
February 10, 2026 at 10:15 AM
Reposted by forterre
Reposted by forterre
~50 kb genomes, 4× smaller than the genomes of 𝘕𝘢𝘳𝘥𝘰𝘯𝘦𝘭𝘭𝘢 sp. 👀 and ~3× smaller than the 𝘊𝘢𝘳𝘴𝘰𝘯𝘦𝘭𝘭𝘢 genome 👀. Elio called 𝘊𝘢𝘳𝘴𝘰𝘯𝘦𝘭𝘭𝘢 ...👇
#SymbioSky
#SymbioSky
February 11, 2026 at 1:38 PM
~50 kb genomes, 4× smaller than the genomes of 𝘕𝘢𝘳𝘥𝘰𝘯𝘦𝘭𝘭𝘢 sp. 👀 and ~3× smaller than the 𝘊𝘢𝘳𝘴𝘰𝘯𝘦𝘭𝘭𝘢 genome 👀. Elio called 𝘊𝘢𝘳𝘴𝘰𝘯𝘦𝘭𝘭𝘢 ...👇
#SymbioSky
#SymbioSky
Reposted by forterre
@carolinamicro.bsky.social Huang & @lbobay.bsky.social investigated genomic rearrangements across 121 microbial species, showing that rearrangements occur at a variable pace across bacteria and archaea, pointing to different selective constraints.
🔗 doi.org/10.1093/gbe/evag002
#genome #evolution
🔗 doi.org/10.1093/gbe/evag002
#genome #evolution
Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria
Abstract. The genetic material of bacteria and archaea is organized into various structures and setups, attesting that genome architecture is dynamic in th
doi.org
February 11, 2026 at 3:57 PM
@carolinamicro.bsky.social Huang & @lbobay.bsky.social investigated genomic rearrangements across 121 microbial species, showing that rearrangements occur at a variable pace across bacteria and archaea, pointing to different selective constraints.
🔗 doi.org/10.1093/gbe/evag002
#genome #evolution
🔗 doi.org/10.1093/gbe/evag002
#genome #evolution
Reposted by forterre
Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved.
It's a fascinating case of molecular mimicry that may help make vaccine safer.🧪
It's a fascinating case of molecular mimicry that may help make vaccine safer.🧪
Rare, dangerous side effects of some COVID-19 vaccines explained
“Groundbreaking” study uncovers why adenovirus-based shots caused life-threatening blood clots and bleeding in some people
www.science.org
February 11, 2026 at 10:10 PM
Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved.
It's a fascinating case of molecular mimicry that may help make vaccine safer.🧪
It's a fascinating case of molecular mimicry that may help make vaccine safer.🧪
Reposted by forterre
Check out our latest preprint from @jnvmartinson.bsky.social and @leosong.bsky.social! 🌟🦠
We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
February 12, 2026 at 12:42 AM
Check out our latest preprint from @jnvmartinson.bsky.social and @leosong.bsky.social! 🌟🦠
We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
Reposted by forterre
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life url: academic.oup.com/nar/article/...
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life
Abstract. Archaea, a domain of microorganisms found in diverse environments, including the human microbiome, represent the closest known prokaryotic relati
academic.oup.com
February 5, 2026 at 6:53 PM
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life url: academic.oup.com/nar/article/...
Reposted by forterre
a daring approach: looking at LUCA's ancestors, i.e. pre-darwinian evolution. but not surprising it's coming from @kacarlab.bsky.social 👏
glad to see Iwabe et al. (1989) among the references (blew my mind when it came out >30 y ago)
glad to see Iwabe et al. (1989) among the references (blew my mind when it came out >30 y ago)
February 6, 2026 at 10:42 PM
a daring approach: looking at LUCA's ancestors, i.e. pre-darwinian evolution. but not surprising it's coming from @kacarlab.bsky.social 👏
glad to see Iwabe et al. (1989) among the references (blew my mind when it came out >30 y ago)
glad to see Iwabe et al. (1989) among the references (blew my mind when it came out >30 y ago)
Reposted by forterre
Note for those interested in Asgard archaea - please join us on the morning of July 10th for a ‘building a community’ discussion!
February 5, 2026 at 4:00 PM
Note for those interested in Asgard archaea - please join us on the morning of July 10th for a ‘building a community’ discussion!
Reposted by forterre
HORBEC are found in most prokaryotes, and are particularly diverse in Archaea. Phylogenetic analyses indicate a complex evolutionary history. However, we show that respiratory complex I (Nuo/Fpo) was likely present in the LUCA, challenging current hypotheses on the ancestral energetic metabolism.
February 3, 2026 at 10:52 AM
HORBEC are found in most prokaryotes, and are particularly diverse in Archaea. Phylogenetic analyses indicate a complex evolutionary history. However, we show that respiratory complex I (Nuo/Fpo) was likely present in the LUCA, challenging current hypotheses on the ancestral energetic metabolism.
Reposted by forterre
𝘌. 𝘤𝘰𝘭𝘪 chromosome replicationists take note 👇
tsutomu katayama's lab tackles one of the last remaining puzzles of DnaB loading by DnaA to 𝘰𝘳𝘪𝘊 after opening. for bi-directional replication, 𝘁𝘄𝗼 DnaB helicases have to be loaded (in case you forgot).
thx for pointing this out, wiep 🙏
#MicroSky
tsutomu katayama's lab tackles one of the last remaining puzzles of DnaB loading by DnaA to 𝘰𝘳𝘪𝘊 after opening. for bi-directional replication, 𝘁𝘄𝗼 DnaB helicases have to be loaded (in case you forgot).
thx for pointing this out, wiep 🙏
#MicroSky
Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication url: academic.oup.com/nar/article/...
Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication
Abstract. Bidirectional replication is a conserved principle requiring coordinated translocation of the two replicative helicases loaded at the origin. In
academic.oup.com
January 31, 2026 at 9:08 PM
𝘌. 𝘤𝘰𝘭𝘪 chromosome replicationists take note 👇
tsutomu katayama's lab tackles one of the last remaining puzzles of DnaB loading by DnaA to 𝘰𝘳𝘪𝘊 after opening. for bi-directional replication, 𝘁𝘄𝗼 DnaB helicases have to be loaded (in case you forgot).
thx for pointing this out, wiep 🙏
#MicroSky
tsutomu katayama's lab tackles one of the last remaining puzzles of DnaB loading by DnaA to 𝘰𝘳𝘪𝘊 after opening. for bi-directional replication, 𝘁𝘄𝗼 DnaB helicases have to be loaded (in case you forgot).
thx for pointing this out, wiep 🙏
#MicroSky
Reposted by forterre
Reposted by forterre
Multiple protein structure alignment at scale with FoldMason | Science https://www.science.org/doi/full/10.1126/science.ads6733?af=R
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended our repository of available protein structures, ...
www.science.org
January 29, 2026 at 11:31 PM
Multiple protein structure alignment at scale with FoldMason | Science https://www.science.org/doi/full/10.1126/science.ads6733?af=R
Reposted by forterre
Emergence and evolution of protein-coding de novo genes | Nature Reviews Genetics https://www.nature.com/articles/s41576-025-00929-9
Emergence and evolution of protein-coding de novo genes - Nature Reviews Genetics
De novo gene evolution entails the birth of new genes from previously non-coding DNA. In this Review, Bornberg-Bauer and Eicholt overview how protein-coding de novo genes are identified, the mechanistic and evolutionary processes underlying their emergence and evolution, and the patterns in their encoded protein structures.
www.nature.com
January 30, 2026 at 3:24 AM
Emergence and evolution of protein-coding de novo genes | Nature Reviews Genetics https://www.nature.com/articles/s41576-025-00929-9
Reposted by forterre
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism
Thermococcales, archaea from hydrothermal vents, promote iron sulfide precipitation, enabling survival in iron-rich environments. Some cells become encrusted in pyrite and do not survive mineralizati...
enviromicro-journals.onlinelibrary.wiley.com
January 26, 2026 at 5:10 AM
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Nice, the authors still use the name Asgard archaea and not Promethearchaeati!
Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures - ScienceDirect https://www.sciencedirect.com/science/article/pii/S0006291X26000653?casa_token=z7fj1ixh3fwAAAAA:8uzKZrbyVwv4nQ8EpXlbRsvLSb3J2253vUfLpezBObbSExu-fGYlVhVBdN-ZAF1HwyRq79-IVa21
Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures
The emergence of internal membrane systems was a defining step in eukaryogenesis, but how pre-eukaryotic proteins were adapted to these novel compartm…
www.sciencedirect.com
January 25, 2026 at 10:39 AM
Nice, the authors still use the name Asgard archaea and not Promethearchaeati!
Reposted by forterre
Fresh news on de novo genes! Happy to present our latest work published in Nature communications: www.nature.com/articles/s41...
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
January 11, 2026 at 7:43 PM
Fresh news on de novo genes! Happy to present our latest work published in Nature communications: www.nature.com/articles/s41...
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
Reposted by forterre
The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?
#microbiology #archaea #GutMicrobiota #MicroSky #ArchaeaSky
www.mdpi.com/2076-0817/14...
#microbiology #archaea #GutMicrobiota #MicroSky #ArchaeaSky
www.mdpi.com/2076-0817/14...
January 4, 2026 at 10:23 AM
The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?
#microbiology #archaea #GutMicrobiota #MicroSky #ArchaeaSky
www.mdpi.com/2076-0817/14...
#microbiology #archaea #GutMicrobiota #MicroSky #ArchaeaSky
www.mdpi.com/2076-0817/14...
Quelle chance! A lire et relire.
January 1, 2026 at 6:16 PM
Quelle chance! A lire et relire.
Reposted by forterre
Le silence pour ce qu’il se passe au Soudan me sidère depuis des mois.
On parle de gens obligés de s’enterrer vivants. Tués à la machette. À la mitraillette. Décapités. Des images satellites montrant un bain de sang.
C’est un génocide.
0 Black Lives Matter.
0 manifestation.
Le silence.
Honteux.
On parle de gens obligés de s’enterrer vivants. Tués à la machette. À la mitraillette. Décapités. Des images satellites montrant un bain de sang.
C’est un génocide.
0 Black Lives Matter.
0 manifestation.
Le silence.
Honteux.
December 30, 2025 at 10:28 PM
Le silence pour ce qu’il se passe au Soudan me sidère depuis des mois.
On parle de gens obligés de s’enterrer vivants. Tués à la machette. À la mitraillette. Décapités. Des images satellites montrant un bain de sang.
C’est un génocide.
0 Black Lives Matter.
0 manifestation.
Le silence.
Honteux.
On parle de gens obligés de s’enterrer vivants. Tués à la machette. À la mitraillette. Décapités. Des images satellites montrant un bain de sang.
C’est un génocide.
0 Black Lives Matter.
0 manifestation.
Le silence.
Honteux.
Reposted by forterre
Large-scale analysis of bacterial genomes reveals thousands of lytic phages | Nature Microbiology https://www.nature.com/articles/s41564-025-02203-4
Large-scale analysis of bacterial genomes reveals thousands of lytic phages - Nature Microbiology
Diverse genomes of lytic phages are found in bacterial assemblies, challenging assumptions about the nature of the lytic lifestyle.
www.nature.com
December 30, 2025 at 12:24 AM
Large-scale analysis of bacterial genomes reveals thousands of lytic phages | Nature Microbiology https://www.nature.com/articles/s41564-025-02203-4
Reposted by forterre
“A process which led from the amoeba to man appeared to the philosophers to be obviously a progress - though whether the amoeba would agree with this opinion is not known"
- Bertrand Russell, 1976.
Time-lapse video of Vampyrella lateritia eating Spirogyra algae from Science Source/Oliver Skibbe. 🦠
- Bertrand Russell, 1976.
Time-lapse video of Vampyrella lateritia eating Spirogyra algae from Science Source/Oliver Skibbe. 🦠
December 17, 2025 at 4:53 PM
“A process which led from the amoeba to man appeared to the philosophers to be obviously a progress - though whether the amoeba would agree with this opinion is not known"
- Bertrand Russell, 1976.
Time-lapse video of Vampyrella lateritia eating Spirogyra algae from Science Source/Oliver Skibbe. 🦠
- Bertrand Russell, 1976.
Time-lapse video of Vampyrella lateritia eating Spirogyra algae from Science Source/Oliver Skibbe. 🦠
A great paper on one of my favourite enzyme. Congratulations to Tamara, her team znd collaborators.
Delighted to share our new preprint: www.biorxiv.org/content/10.6...
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
www.biorxiv.org
December 11, 2025 at 7:22 PM
A great paper on one of my favourite enzyme. Congratulations to Tamara, her team znd collaborators.
Reposted by forterre
Aujourd’hui, nous célébrons les 120 ans de la loi du 9 décembre 1905, texte fondateur de la laïcité en France.
Liberté de croire ou de ne pas croire et neutralité de l’État : elle est l’un des piliers de notre vivre-ensemble. Continuons à en être les garants.
Liberté de croire ou de ne pas croire et neutralité de l’État : elle est l’un des piliers de notre vivre-ensemble. Continuons à en être les garants.
December 9, 2025 at 8:32 AM
Aujourd’hui, nous célébrons les 120 ans de la loi du 9 décembre 1905, texte fondateur de la laïcité en France.
Liberté de croire ou de ne pas croire et neutralité de l’État : elle est l’un des piliers de notre vivre-ensemble. Continuons à en être les garants.
Liberté de croire ou de ne pas croire et neutralité de l’État : elle est l’un des piliers de notre vivre-ensemble. Continuons à en être les garants.
Reposted by forterre
Subcellular organization of the archaeal cell
#archaea #microbiology sciencedirect.com/science/arti...
#archaea #microbiology sciencedirect.com/science/arti...
December 9, 2025 at 8:56 AM
Subcellular organization of the archaeal cell
#archaea #microbiology sciencedirect.com/science/arti...
#archaea #microbiology sciencedirect.com/science/arti...