Petros Ligoxygakis
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petrosligoxygakis.bsky.social
Petros Ligoxygakis
@petrosligoxygakis.bsky.social
1.9K followers 1.3K following 100 posts
Studying host-pathogen interactions, immunity beyond infection. Prof of Immunology at Oxford University and Fellow/Tutor at Hertford College. #Innate Immunity #Drosophila
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petrosligoxygakis.bsky.social
Rough streets…Το όνομα μιας συλλογής που επιμελήθηκε (83;). 45άρια της Rough Trade. Ερχόμενος Αγγλία το πρώτο πράγμα ήταν να τα βρω. The Zounds, Blue Orchids, Virgin Prunes, Pere Ubu, Pop Group, etc. Δεν νομίζω να υπάρχει άνθρωπος που να επηρέασε τόσο πολύ τι άκουγα τότε. www.lifo.gr/now/entertai...
Πέθανε ο μουσικοκριτικός Αργύρης Ζήλος | LiFO
Τα τελευταία χρόνια είχε αποσυρθεί από τον παλιό, πιο εντατικό επαγγελματικό ρυθμό γραφής και κριτικής
www.lifo.gr
November 19, 2025 at 7:21 PM
petrosligoxygakis.bsky.social
One of the greats. For years I was thinking that one ought to take his papers and write a study of their repercussions, extensions and influence. His inquisitive mind was described to me “[…] as a blind rhinoceros running in a burning savannah”. I can only imagine those group meetings…
November 19, 2025 at 11:19 AM
Reposted by Petros Ligoxygakis
carissaveliz.bsky.social
Drumrolls, please! I’m thrilled to share the cover for my forthcoming #book from @doubledaybooks.bsky.social
(Penguin Random House), #PROPHECY. This is the best book I’ve written: the boldest, the most innovative, the most personal. I have poured my soul into it like never before. 1/
November 17, 2025 at 10:35 AM
Reposted by Petros Ligoxygakis
embojournal.org
How can gut microbes modulate host lifespan?
@jogender-singh.bsky.social & coworkers show that in C. elegans, lifespan extension arises from microbial perturbation of iron homeostasis and oxidative stress response activation
#RefereedPreprint c/o @reviewcommons.org
www.embopress.org/doi/full/10....
November 17, 2025 at 1:22 PM
Reposted by Petros Ligoxygakis
profsimonfisher.bsky.social
Advances in genomics are giving exciting new perspectives on biology of speech, language & reading. My latest peer-reviewed paper is a tutorial, guiding readers from different backgrounds through the history of the field, current state-of-the-art, & where we’re heading. A taster in this thread.🧪
1/n
Genomic Investigations of Spoken and Written Language Abilities: A Guide to Advances in Approaches, Technologies, and Discovery
Purpose: The aim of this tutorial is to show how the rise of molecular technologies and analytical methods in human genetics yields exciting new ...
pubs.asha.org
November 17, 2025 at 5:54 PM
petrosligoxygakis.bsky.social
So devastatingly true. Read this thread.
grimalkina.bsky.social Cat Hicks @grimalkina.bsky.social · 11d
His comments were not going out to nowhere. He directly told the brilliant and incredible grad students, postdocs, particularly people he had no reason to fear because they were in vulnerable and low power positions -- that they did not belong in science

bsky.app/profile/anal...
analog-ashley.bsky.social ashley juavinett @analog-ashley.bsky.social · 12d
When I was a postdoc, CSHL held a Burns poetry night, which Watson attended.

I did a dramatic reading of Ice Ice Baby.

I hope he found it deeply offensive, and that the graduate students (many of whom he told didn't belong there) found it at least mildly entertaining.

This is a good day for CSHL.
November 17, 2025 at 3:10 AM
Reposted by Petros Ligoxygakis
grimalkina.bsky.social
We are in the midst of an all-out attempt to exclude the global majority from science. Watson was clear about where he fell on that. I would trade every single dinner, meeting, seminar, fancy campus, and prestigious donor for my incredible friends to be safer. Their science is worth far more.
November 8, 2025 at 5:24 PM
petrosligoxygakis.bsky.social
Elegant chaos
dj-acid-reflux.bsky.social Tom Cox @dj-acid-reflux.bsky.social · 4d
THREAD. How The Singer Julian Cope Licked My Entire Face And Hypnotised Me Into An Occult Life On The Margins Of Society

I have been wanting to tell this true story - arguably the central one of my life - for many years.

You will find it in the alt text to these very real documentary photographs.
A lot of people ask me why I am the way I am, so, after many years of holding back, I thought it was time to come clean. The truth is, it all dates back to the day in summer 1994 in the Nottingham branch of Virgin Megastore when the musician Julian Cope - who, it transpired, had been stalking me all over the city from a furtive distance on his hands and knees for several days - licked every bit of my face, coating it in his mystical saliva.
November 15, 2025 at 7:37 AM
Reposted by Petros Ligoxygakis
wcratcliff.bsky.social
Let me use this as an opportunity to talk about Jordi et al's very cool paper, now out in PNAS 🧪:

pmc.ncbi.nlm.nih.gov/articles/PMC...

You can read our news and views here: www.pnas.org/doi/10.1073/...
November 13, 2025 at 4:13 PM
Reposted by Petros Ligoxygakis
josetelesreis.bsky.social
Excited to share our new paper out in Cell Reports Methods! @cp-cellrepmethods.bsky.social
🎉🎉🎉
We present EyaHOST, a modular Drosophila genetic system that enables precise and independent manipulation of tumours and host tissues to dissect tumour-host interactions.
www.cell.com/cell-reports...
EyaHOST, a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster
Teles-Reis et al. present EyaHOST, a modular Drosophila system that enables clone generation in the eye disc with independent genetic manipulation of other tissues. EyaHOST uses an Eya-KD “kick-out” s...
www.cell.com
November 5, 2025 at 11:07 PM
Reposted by Petros Ligoxygakis
hansonmark.bsky.social
We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing:

a 🧵 1/n

Drain: arxiv.org/abs/2511.04820
Strain: direct.mit.edu/qss/article/...
Oligopoly: direct.mit.edu/qss/article/...
A table showing profit margins of major publishers. A snippet of text related to this table is below. 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year. A figure detailing the drain on researcher time. 1. The four-fold drain 1.2 Time The number of papers published each year is growing faster than the scientific workforce, with the number of papers per researcher almost doubling between 1996 and 2022 (Figure 1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material has aligned well with the competitive prestige culture in which publications help secure jobs, grants, promotions, and awards. To the extent that this growth is driven by a pressure for profit, rather than scholarly imperatives, it distorts the way researchers spend their time. The publishing system depends on unpaid reviewer labour, estimated to be over 130 million unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of peer-review for decades, but the scale of the problem is now worse, with editors reporting widespread difficulties recruiting reviewers. The growth in publications involves not only the authors’ time, but that of academic editors and reviewers who are dealing with so many review demands. Even more seriously, the imperative to produce ever more articles reshapes the nature of scientific inquiry. Evidence across multiple fields shows that more papers result in ‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow progress until one considers how it affects researchers’ time. While rewards remain tied to volume, prestige, and impact of publications, researchers will be nudged away from riskier, local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with limited progress whereas core scholarly practices – such as reading, reflecting and engaging with others’ contributions – is de-prioritized. What looks like productivity often masks intellectual exhaustion built on a demoralizing, narrowing scientific vision. A table of profit margins across industries. The section of text related to this table is below: 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year. The costs of inaction are plain: wasted public funds, lost researcher time, compromised scientific integrity and eroded public trust. Today, the system rewards commercial publishers first, and science second. Without bold action from the funders we risk continuing to pour resources into a system that prioritizes profit over the advancement of scientific knowledge.
November 11, 2025 at 11:52 AM
Reposted by Petros Ligoxygakis
mariapopova.bsky.social
“Living beings defy neat definition… We abide in a symbiotic world.”

The visionary evolutionary biologist Lynn Margulis (of Gaia Hypothesis fame) on symbiosis and the unself www.themarginalian.org/2022/12/21/l...
Symbiosis and the Unself: Evolutionary Biologist Lynn Margulis on How Interbeing Shapes Life on Earth
“Living beings defy neat definition… We abide in a symbiotic world.”
www.themarginalian.org
November 10, 2025 at 1:22 AM
Reposted by Petros Ligoxygakis
motherslug.bsky.social
My latest review for Uncut!
November 9, 2025 at 6:11 PM
Reposted by Petros Ligoxygakis
richardsever.bsky.social
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n

openrxiv.org/enabling-rev...
Enabling options for review: from training and transparency to author-centered AI tools - openRxiv
Peer review is widely viewed as a critical aspect of biomedical communication. Ideally, it provides authors with feedback so they can improve manuscripts and gives readers, particularly nonspecialists...
openrxiv.org
November 6, 2025 at 2:32 PM
petrosligoxygakis.bsky.social
The fightback begins www.nytimes.com/live/2025/11...
N.Y.C. Mayor Live Updates: ‘This City Belongs to You,’ Mamdani Says as He Celebrates Victory
www.nytimes.com
November 5, 2025 at 8:12 AM
Reposted by Petros Ligoxygakis
halcyene.bsky.social
"The point is to change it" — a volume of new essays from 21 leading academics exploring the role of philosophy in public life — launches today!

Contributors include @tariqmodood.bsky.social, @martinoneill.bsky.social, @jowolff.bsky.social, @elkeschwarz.bsky.social and more.

Click below to read 👇🦉
Essays on philosophy in public life - Nuffield Foundation
www.nuffieldfoundation.org
November 3, 2025 at 9:47 AM
petrosligoxygakis.bsky.social
In the small part of the world my mind and ears inhabit since I was a teenager, the Huskers were the embodiment of songwriting coolness: thoughtful storytelling, integrity and high speed/noise rock and roll rage. Pushing boundaries and taking no prisoners. Forever faithful.
thequietus.com The Quietus @thequietus.com · 17d
"To watch #Nirvana and The Offspring and Green Day and #Pixies blow up was crazy. I think it’s great they got paid and went on to have amazing careers, but… It’s like we were professional athletes before all the TV money came in and contracts exploded"

#HüskerDü Interviewed

buff.ly/k3f6SEV
Black and white photograph of Husker Du, sat at an outdoors table marked with a chess board. Greg and Grant are wearing hats.
November 2, 2025 at 6:12 PM
Reposted by Petros Ligoxygakis
labgrosshans.bsky.social
Nektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
doi.org
October 29, 2025 at 11:57 AM
Reposted by Petros Ligoxygakis
nejm.org
Results from recently published, peer-reviewed studies support the safety and effectiveness of immunizations against Covid-19, RSV, and influenza. Learn more in a Special Article: nej.md/3L8m1gt

#MedSky #IDSky
Forest plots showing population-specific vaccine effectiveness against hospitalization for Covid-19 on the basis of case–control and cohort studies.
October 29, 2025 at 9:10 PM
Reposted by Petros Ligoxygakis
dkutsumba.bsky.social
Το κείμενο αυτό το έγραψα με πολύ πνευματικό και ψυχικό κάματο, αλλά όχι εν θερμώ. Θα ήθελα να το διαβάσετε και θα ήθελα και τη γνώμη σας.
Από τη Μακρόνησο στον Άγνωστο, η τεχνολογία διακυβέρνησης της δεξιάς έχει τον ίδιο πυρήνα.
epohi.gr/articles/kat...
October 24, 2025 at 3:05 PM
Reposted by Petros Ligoxygakis
tetherin.bsky.social
SARS CoV-2 mRNA vaccines cause Turbo cancer….immunotherapy

Yes, they help stimulate innate immunity in those undergoing checkpoint inhibitor therapy to improve outcome

Like to see how grifters like Malhotra, Dalgleish, the BSNow crew and of course JayB/RFK spin this
www.nature.com/articles/s41...
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
www.nature.com
October 23, 2025 at 6:49 AM
petrosligoxygakis.bsky.social
Εμείς, του 60 οι εκδρομείς…
h-gkriniara.bsky.social Γκρινιάρα @h-gkriniara.bsky.social · 29d
Σαββόπουλος είναι όλη μου η παιδική ηλικία, τα ταξιδια με τον μπαμπά μου -χωρις τη μάνα μου που δε μας άφηνε να ακούμε μουσική- και ακούγαμε το μην πετάξεις τίποτα, σχεδόν κρυφά κι ας ήμασταν οι δυο μας. Είναι η ακατανίκητη έλξη του Φορτηγού στα τέλη του Λυκείου και ο Πολιτευτής, όταν
October 21, 2025 at 8:22 PM
petrosligoxygakis.bsky.social
Sounds like great fun! Already thinking of a storyline.
helenahartmann.com Dr. Helena Hartmann (she/her) @helenahartmann.com · Oct 18
Have you ever tried explaining your research with ... a short story?! 🤔

Believe me, it's extremely gratifying to change your perspective and let your creativity run loose. 💙

Then YOU can be a guest author for @scienceandfiction.net! 😱

DM me for more info 😁
scienceandfiction.net Science & Fiction @scienceandfiction.net · Jun 26
This is 💙 Science & Fiction 💙 where scientific results & fictional stories intersect.

A space for people who like to a) learn about #science & b) read exciting fictional stories ✨

🇬🇧 www.scienceandfiction.net
🇩🇪 www.scienceandfiction.net/de

Support: ko-fi.com/scienceandfi...

#scicomm #wisskomm
October 18, 2025 at 12:45 PM
Reposted by Petros Ligoxygakis
mmorrissey.bsky.social
We have TWO papers out in @jcb.org this month! 🎉

First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social

doi.org/10.1083/jcb....
October 17, 2025 at 5:07 PM
Reposted by Petros Ligoxygakis
castellosanjuan.bsky.social
I'm so excited to share this with all of you!
This is the very first paper where I am the first author 🥹
Let me share some insights about our work 👇🧵(1/5):

How do persistent viral infections impact the host?

What happens when a fly becomes persistently infected by a virus?
October 17, 2025 at 2:07 PM