Grosshans Lab
@labgrosshans.bsky.social
Studying mechanisms of developmental clocks and timers at the Friedrich Miescher Institute for Biomedical Research, Basel.
Pinned
Grosshans Lab
@labgrosshans.bsky.social
· Oct 10
Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
Reposted by Grosshans Lab
👩🔬 On February 11, to mark the International Day of Women and Girls in Science, we’re hosting a panel discussion on how scientific progress and gender equality can advance together. The panel brings together voices from academia, industry, and EDI. Join us for this important conversation!
#IDWGS
#IDWGS
February 6, 2026 at 7:08 AM
👩🔬 On February 11, to mark the International Day of Women and Girls in Science, we’re hosting a panel discussion on how scientific progress and gender equality can advance together. The panel brings together voices from academia, industry, and EDI. Join us for this important conversation!
#IDWGS
#IDWGS
Reposted by Grosshans Lab
Now out in @currentbiology.bsky.social: neuroscientists in the lab of @felsenberg.bsky.social found that in fruit flies, re-tasting a sugar reward can weaken past memories, pointing to new ways to safely update harmful ones. www.fmi.ch/news-events/...
How a sweet treat can change memories
Memories must be flexible so animals can adapt when the world changes. FMI neuroscientists found that in fruit flies, simply tasting a sugar reward again can weaken all previous associated memories. T...
www.fmi.ch
February 5, 2026 at 10:10 AM
Now out in @currentbiology.bsky.social: neuroscientists in the lab of @felsenberg.bsky.social found that in fruit flies, re-tasting a sugar reward can weaken past memories, pointing to new ways to safely update harmful ones. www.fmi.ch/news-events/...
Reposted by Grosshans Lab
Very thankful for this thoughtful dispatch by @shaisrael.bsky.social sky.social and Moshe Parnas about our work. Learning and memory: Forgetting to remember: Current Biology www.cell.com/current-biol...
February 5, 2026 at 1:24 PM
Very thankful for this thoughtful dispatch by @shaisrael.bsky.social sky.social and Moshe Parnas about our work. Learning and memory: Forgetting to remember: Current Biology www.cell.com/current-biol...
Reposted by Grosshans Lab
Our annual brochure “Year in Review” is out now! It highlights the FMI’s key scientific publications, major events, and facts & figures from 2025, a year that marked our 55th anniversary.
www.fmi.ch/news-events/...
www.fmi.ch/news-events/...
FMI Year in Review 2025
Our annual brochure highlighting the FMI’s key scientific publications, major events, and facts & figures from the past year is now available. Discover the highlights of 2025, a year that marked the F...
www.fmi.ch
January 19, 2026 at 2:50 PM
Our annual brochure “Year in Review” is out now! It highlights the FMI’s key scientific publications, major events, and facts & figures from 2025, a year that marked our 55th anniversary.
www.fmi.ch/news-events/...
www.fmi.ch/news-events/...
Reposted by Grosshans Lab
Prof. Fiona Doetsch has been awarded the 2026 Louis-Jeantet Prize for Medicine!
Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠
Read more: www.biozentrum.unibas.ch/news/detail/...
Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠
Read more: www.biozentrum.unibas.ch/news/detail/...
January 15, 2026 at 10:09 AM
Prof. Fiona Doetsch has been awarded the 2026 Louis-Jeantet Prize for Medicine!
Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠
Read more: www.biozentrum.unibas.ch/news/detail/...
Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠
Read more: www.biozentrum.unibas.ch/news/detail/...
RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...
January 15, 2026 at 7:48 AM
RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...
Please repost - position of Head of Student & Postdoc Affairs available at our Institute in the heart of Europe (Basel, Switzerland) 👇
📢 Please help spread the word: We’re hiring a Head of Student & Postdoc Affairs to coordinate our international PhD program, provide guidance & career counseling, lead training programs, collaborate on EDI initiatives, and manage alumni relations. Apply at www.fmi.ch/education-ca...
December 8, 2025 at 11:47 AM
Please repost - position of Head of Student & Postdoc Affairs available at our Institute in the heart of Europe (Basel, Switzerland) 👇
Reposted by Grosshans Lab
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
November 25, 2025 at 6:18 AM
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
Reposted by Grosshans Lab
Switzerland is joining Horizon Europe!
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
November 10, 2025 at 2:58 PM
Switzerland is joining Horizon Europe!
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
Reposted by Grosshans Lab
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 6, 2025 at 4:35 AM
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
Reposted by Grosshans Lab
Now in @embojournal.org: Researchers in @labgrosshans.bsky.social & UCSC found that similar molecular machineries control daily circadian rhythms & developmental timing—showing that evolution can repurpose core timing systems to coordinate both daily cycles & growth. www.fmi.ch/news-events/...
One clock, two functions: from daily rhythms to development
Scientists at the FMI and the University of California-Santa Cruz have found that similar molecular machineries control daily circadian rhythms and developmental timing. Their work in worms shows that...
www.fmi.ch
November 4, 2025 at 8:28 AM
Now in @embojournal.org: Researchers in @labgrosshans.bsky.social & UCSC found that similar molecular machineries control daily circadian rhythms & developmental timing—showing that evolution can repurpose core timing systems to coordinate both daily cycles & growth. www.fmi.ch/news-events/...
Reposted by Grosshans Lab
Here is the schedule for the next TriRhena Gene Regulation Club at the FMI @fmiscience.bsky.social in Basel 🇨🇭 next week (5 Nov 2025; 14:00-18:45).
Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI).
www.ie-freiburg.mpg.de/grc
Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI).
www.ie-freiburg.mpg.de/grc
October 30, 2025 at 9:17 AM
Here is the schedule for the next TriRhena Gene Regulation Club at the FMI @fmiscience.bsky.social in Basel 🇨🇭 next week (5 Nov 2025; 14:00-18:45).
Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI).
www.ie-freiburg.mpg.de/grc
Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI).
www.ie-freiburg.mpg.de/grc
Nektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
doi.org
October 29, 2025 at 11:57 AM
Nektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...
Flying worms! www.science.org/content/arti... (And I always wondered how worm cuticular alae (= wings) got their name 😉)
Bull’s-eye! Static electricity pulls worm through air to its insect victim
Electrostatic charges may help roundworms infect a wide variety of hosts
www.science.org
October 29, 2025 at 8:08 AM
Flying worms! www.science.org/content/arti... (And I always wondered how worm cuticular alae (= wings) got their name 😉)
Reposted by Grosshans Lab
🔬 Next in the NCCR RNA & Disease Seminar Series: Prof. Olivia Rissland (Univ. of Colorado School of Medicine, USA)!
📅 27.10. 16:30 – University of Bern, DCBP
📅 28.10. 15:00 – ETH Zurich, Hönggerberg
👉 More info: nccr-rna-and-disease.ch/education/nc...
@unibe.ch @ethz.ch @snf-fns.ch
📅 27.10. 16:30 – University of Bern, DCBP
📅 28.10. 15:00 – ETH Zurich, Hönggerberg
👉 More info: nccr-rna-and-disease.ch/education/nc...
@unibe.ch @ethz.ch @snf-fns.ch
October 24, 2025 at 7:09 AM
🔬 Next in the NCCR RNA & Disease Seminar Series: Prof. Olivia Rissland (Univ. of Colorado School of Medicine, USA)!
📅 27.10. 16:30 – University of Bern, DCBP
📅 28.10. 15:00 – ETH Zurich, Hönggerberg
👉 More info: nccr-rna-and-disease.ch/education/nc...
@unibe.ch @ethz.ch @snf-fns.ch
📅 27.10. 16:30 – University of Bern, DCBP
📅 28.10. 15:00 – ETH Zurich, Hönggerberg
👉 More info: nccr-rna-and-disease.ch/education/nc...
@unibe.ch @ethz.ch @snf-fns.ch
Reposted by Grosshans Lab
For what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. davidfay@uwyo.edu
scholar.google.com/citations?us...
scholar.google.com/citations?us...
October 22, 2025 at 1:28 PM
For what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. davidfay@uwyo.edu
scholar.google.com/citations?us...
scholar.google.com/citations?us...
And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n
October 20, 2025 at 1:25 PM
And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n
Reposted by Grosshans Lab
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
October 16, 2025 at 5:29 PM
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
And here is a layperson video summary of parts of our recent paper👇
🎥 FMI scientists discovered that thousands of C. elegans genes switch on and off in rhythmic patterns controlled by chromatin, revealing how gene timing shapes development & offering clues to human biological clocks. @labgrosshans.bsky.social www.youtube.com/watch?v=Dibw...
DNA rhythms orchestrate gene activity across development
YouTube video by The Friedrich Miescher Institute for Biomedical Research
www.youtube.com
October 15, 2025 at 10:39 AM
And here is a layperson video summary of parts of our recent paper👇
Reposted by Grosshans Lab
🎥 FMI scientists discovered that thousands of C. elegans genes switch on and off in rhythmic patterns controlled by chromatin, revealing how gene timing shapes development & offering clues to human biological clocks. @labgrosshans.bsky.social www.youtube.com/watch?v=Dibw...
DNA rhythms orchestrate gene activity across development
YouTube video by The Friedrich Miescher Institute for Biomedical Research
www.youtube.com
October 15, 2025 at 6:58 AM
🎥 FMI scientists discovered that thousands of C. elegans genes switch on and off in rhythmic patterns controlled by chromatin, revealing how gene timing shapes development & offering clues to human biological clocks. @labgrosshans.bsky.social www.youtube.com/watch?v=Dibw...
Watch Lucas' amazing artistic/musical rendition of C. elegans larval development and our work on developmental timing and molting here youtu.be/-hGHYRvw87w and read on his inspiration and challenges below
October 13, 2025 at 7:59 AM
Watch Lucas' amazing artistic/musical rendition of C. elegans larval development and our work on developmental timing and molting here youtu.be/-hGHYRvw87w and read on his inspiration and challenges below
Reposted by Grosshans Lab
October 12, 2025 at 9:25 AM
Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
October 10, 2025 at 2:17 PM
Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
Reposted by Grosshans Lab
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
aECM Club Seminars
A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…
sundaramlab.com
September 23, 2025 at 9:10 AM
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
Reposted by Grosshans Lab
Another FMI Annual Meeting is in the books! After a night of follies and plenty of dancing, today brought the announcement of our internal prize winners, more inspiring talks, and a vibrant poster session. Already looking forward to next year! 🙌
September 17, 2025 at 11:57 AM
Another FMI Annual Meeting is in the books! After a night of follies and plenty of dancing, today brought the announcement of our internal prize winners, more inspiring talks, and a vibrant poster session. Already looking forward to next year! 🙌