Patrick Bafuma PA-C
@pbafuma.bsky.social
EM-turned critical care PA.
POCUS, dogmalytics, & infectious disease.
Formerly a mastiff, now a dobie.
POCUS, dogmalytics, & infectious disease.
Formerly a mastiff, now a dobie.
@albertvilella.bsky.social how does Google's offering affect 10x Genomics, it at all?
Possibly help by increased awareness/curiosity? Is there a chance it pulls business away eventually?
research.google/blog/teachin...
Possibly help by increased awareness/curiosity? Is there a chance it pulls business away eventually?
research.google/blog/teachin...
Teaching machines the language of biology: Scaling large language models for next-generation single-cell analysis
research.google
October 19, 2025 at 5:32 AM
@albertvilella.bsky.social how does Google's offering affect 10x Genomics, it at all?
Possibly help by increased awareness/curiosity? Is there a chance it pulls business away eventually?
research.google/blog/teachin...
Possibly help by increased awareness/curiosity? Is there a chance it pulls business away eventually?
research.google/blog/teachin...
Over last few years, have started to feel ketamine for pain probably a rescue tactic at best. Lots of better options.
If I can't block, precedex >>>> ketamine for pain control.
journals.lww.com/anesthesia-a...
#EMIMCC
If I can't block, precedex >>>> ketamine for pain control.
journals.lww.com/anesthesia-a...
#EMIMCC
Effect of Low-Dose Ketamine Infusion in the Intensive Care... : Anesthesia & Analgesia
journals.lww.com
August 31, 2025 at 9:34 PM
Over last few years, have started to feel ketamine for pain probably a rescue tactic at best. Lots of better options.
If I can't block, precedex >>>> ketamine for pain control.
journals.lww.com/anesthesia-a...
#EMIMCC
If I can't block, precedex >>>> ketamine for pain control.
journals.lww.com/anesthesia-a...
#EMIMCC
Reposted by Patrick Bafuma PA-C
Way to go, San Francisco!! 👏👏
August 23, 2025 at 10:34 PM
Way to go, San Francisco!! 👏👏
Reposted by Patrick Bafuma PA-C
Reposted by Patrick Bafuma PA-C
Shift one as an attending intensivist in the books. Thanks for the encouragement y'all. Shout out to @pbafuma.bsky.social for putting up with the new shift jitters and orienting.
July 17, 2025 at 11:36 PM
Shift one as an attending intensivist in the books. Thanks for the encouragement y'all. Shout out to @pbafuma.bsky.social for putting up with the new shift jitters and orienting.
Peds: still little adults!
In children with septic shock and no known cardiac dysfunction, starting treatment with norepinephrine rather than epinephrine was associated with lower 30-day mortality.
#CCR25 #MedSky
ja.ma/4kXryTp
#CCR25 #MedSky
ja.ma/4kXryTp
June 11, 2025 at 3:46 PM
Peds: still little adults!
Opioid deaths down significantly in 2024.
Anticipate this trend for years, and that Trump will (erroneously but inevitably) claim victory...
When it's years I'm the making and multifactorial + this generation just doesn't imbibe in drugs & alcohol like prior genz.
www.dea.gov/press-releas...
Anticipate this trend for years, and that Trump will (erroneously but inevitably) claim victory...
When it's years I'm the making and multifactorial + this generation just doesn't imbibe in drugs & alcohol like prior genz.
www.dea.gov/press-releas...
February 13, 2025 at 1:53 PM
Opioid deaths down significantly in 2024.
Anticipate this trend for years, and that Trump will (erroneously but inevitably) claim victory...
When it's years I'm the making and multifactorial + this generation just doesn't imbibe in drugs & alcohol like prior genz.
www.dea.gov/press-releas...
Anticipate this trend for years, and that Trump will (erroneously but inevitably) claim victory...
When it's years I'm the making and multifactorial + this generation just doesn't imbibe in drugs & alcohol like prior genz.
www.dea.gov/press-releas...
@omnintensivist.bsky.social are you seeing/hearing about this??
February 10, 2025 at 6:26 PM
@omnintensivist.bsky.social are you seeing/hearing about this??
Interesting concept here. Certain antiseizure meds as CV risk for Older folks with epilepsy?
pubmed.ncbi.nlm.nih.gov/39804367/
#EMIMCC #neurosky
pubmed.ncbi.nlm.nih.gov/39804367/
#EMIMCC #neurosky
Antiseizure Medications and Cardiovascular Events in Older People With Epilepsy in the Canadian Longitudinal Study on Aging - PubMed
Results of this cohort study reveal that epilepsy was associated with new-onset CVEs. Nearly one-third of this association can be explained by EIASMs. These findings should be considered when choosing...
pubmed.ncbi.nlm.nih.gov
January 28, 2025 at 4:31 AM
Interesting concept here. Certain antiseizure meds as CV risk for Older folks with epilepsy?
pubmed.ncbi.nlm.nih.gov/39804367/
#EMIMCC #neurosky
pubmed.ncbi.nlm.nih.gov/39804367/
#EMIMCC #neurosky
Reposted by Patrick Bafuma PA-C
For no reason:
In 🇸🇪, 98% & 99% ⬇️ in HPV16 and 18 (main cervical cancer causing types) prevalence, respectively, in cervical samples from 2000-born (82-83% HPV vaccine coverage) vs 1984-born (unvaccinated) women
Vaccines are amazing!
academic.oup.com/jid/advance-...
In 🇸🇪, 98% & 99% ⬇️ in HPV16 and 18 (main cervical cancer causing types) prevalence, respectively, in cervical samples from 2000-born (82-83% HPV vaccine coverage) vs 1984-born (unvaccinated) women
Vaccines are amazing!
academic.oup.com/jid/advance-...
January 22, 2025 at 4:13 PM
For no reason:
In 🇸🇪, 98% & 99% ⬇️ in HPV16 and 18 (main cervical cancer causing types) prevalence, respectively, in cervical samples from 2000-born (82-83% HPV vaccine coverage) vs 1984-born (unvaccinated) women
Vaccines are amazing!
academic.oup.com/jid/advance-...
In 🇸🇪, 98% & 99% ⬇️ in HPV16 and 18 (main cervical cancer causing types) prevalence, respectively, in cervical samples from 2000-born (82-83% HPV vaccine coverage) vs 1984-born (unvaccinated) women
Vaccines are amazing!
academic.oup.com/jid/advance-...
I've had 3 colleagues at @unm.edu reach out to ask if we were ok in the fires. (We're an hour away and totally fine)
Even though it's a travel assignment, these folks are top notch people. Love the ICU staff there.
Even though it's a travel assignment, these folks are top notch people. Love the ICU staff there.
January 11, 2025 at 5:21 AM
I've had 3 colleagues at @unm.edu reach out to ask if we were ok in the fires. (We're an hour away and totally fine)
Even though it's a travel assignment, these folks are top notch people. Love the ICU staff there.
Even though it's a travel assignment, these folks are top notch people. Love the ICU staff there.
Reposted by Patrick Bafuma PA-C
Sometimes you can't spell ECMO without CMO.
December 28, 2024 at 9:11 AM
Sometimes you can't spell ECMO without CMO.
Reposted by Patrick Bafuma PA-C
I just plugged a USB in the correct way on the first try AMA
December 16, 2024 at 9:11 PM
I just plugged a USB in the correct way on the first try AMA
Curious what #pharmSky and #icusky think of this ...
Gotta say I'm intrigued.... Maybe a 1x dose for delirium preventing vent weaning? 🤔🤔
pubmed.ncbi.nlm.nih.gov/39648603/
Gotta say I'm intrigued.... Maybe a 1x dose for delirium preventing vent weaning? 🤔🤔
pubmed.ncbi.nlm.nih.gov/39648603/
Valproic Acid for Hyperactive Delirium and Agitation in Critically Ill Patients - PubMed
The addition of VPA to a complex pharmacologic regimen for hyperactive delirium and agitation is safe and can assist in the prevention of polypharmacy and overall workload in critically ill patients a...
pubmed.ncbi.nlm.nih.gov
December 15, 2024 at 12:22 AM
Curious what #pharmSky and #icusky think of this ...
Gotta say I'm intrigued.... Maybe a 1x dose for delirium preventing vent weaning? 🤔🤔
pubmed.ncbi.nlm.nih.gov/39648603/
Gotta say I'm intrigued.... Maybe a 1x dose for delirium preventing vent weaning? 🤔🤔
pubmed.ncbi.nlm.nih.gov/39648603/
Reposted by Patrick Bafuma PA-C
The data is week for lifelong ASS for secondary prevention in CAD. Are we causing more bleeds than preventing MI…?
It will either take some strong advocates or new trials to overcome status-quo-bias.
#cardiosky
jamanetwork.com/journals/jam...
It will either take some strong advocates or new trials to overcome status-quo-bias.
#cardiosky
jamanetwork.com/journals/jam...
Aspirin for Secondary Prevention of Atherosclerosis
Decades of recommendations to give aspirin for primary prevention of cardiovascular events, based on overoptimistic interpretation of inconclusive data, were recently overturned after a randomized cli...
jamanetwork.com
December 14, 2024 at 10:17 PM
The data is week for lifelong ASS for secondary prevention in CAD. Are we causing more bleeds than preventing MI…?
It will either take some strong advocates or new trials to overcome status-quo-bias.
#cardiosky
jamanetwork.com/journals/jam...
It will either take some strong advocates or new trials to overcome status-quo-bias.
#cardiosky
jamanetwork.com/journals/jam...
Central line hack:
That small clear blue plastic piece at the end of the guide wire COMES OFF. If you have ever struggled with initially threading the wire off the plastic holder tubing thing... THIS IS FOR YOU
That small clear blue plastic piece at the end of the guide wire COMES OFF. If you have ever struggled with initially threading the wire off the plastic holder tubing thing... THIS IS FOR YOU
December 14, 2024 at 3:53 AM
Central line hack:
That small clear blue plastic piece at the end of the guide wire COMES OFF. If you have ever struggled with initially threading the wire off the plastic holder tubing thing... THIS IS FOR YOU
That small clear blue plastic piece at the end of the guide wire COMES OFF. If you have ever struggled with initially threading the wire off the plastic holder tubing thing... THIS IS FOR YOU
Getting into the heart of flu season seems like a good time to mention that there's >20% rate of co-infection.
A trial of abx for the critically ill flu patient until the smoke clears totally reasonable. #emimcc #IDsky
pmc.ncbi.nlm.nih.gov/articles/PMC...
A trial of abx for the critically ill flu patient until the smoke clears totally reasonable. #emimcc #IDsky
pmc.ncbi.nlm.nih.gov/articles/PMC...
The prevalence of influenza bacterial co-infection and its role in disease severity: A systematic review and meta-analysis
Evidence suggests that influenza bacterial co-infection is associated with severe diseases, but this association has not been systematically assessed. We aimed to assess the prevalence of influenza ba...
pmc.ncbi.nlm.nih.gov
December 12, 2024 at 11:52 AM
Getting into the heart of flu season seems like a good time to mention that there's >20% rate of co-infection.
A trial of abx for the critically ill flu patient until the smoke clears totally reasonable. #emimcc #IDsky
pmc.ncbi.nlm.nih.gov/articles/PMC...
A trial of abx for the critically ill flu patient until the smoke clears totally reasonable. #emimcc #IDsky
pmc.ncbi.nlm.nih.gov/articles/PMC...
The borg does not win this round.... For now.
December 11, 2024 at 1:47 PM
The borg does not win this round.... For now.
Reposted by Patrick Bafuma PA-C
Developing: Pennsylvania Burger King chains have updated their slogan:
"Here, snitches get stitches"
"Here, snitches get stitches"
December 9, 2024 at 9:31 PM
Developing: Pennsylvania Burger King chains have updated their slogan:
"Here, snitches get stitches"
"Here, snitches get stitches"
One of few trials to show a difference for PCT. But is it worth it? They saved a day of abx (8.1d vs 7d PCT vs SoC) 🤷♂️
Is the cost of procal for everyone worth it? especially when
1) we know less duration is better
2) no difference in outcomes
3) multiple studies show *more* abx when you use PCT.
Is the cost of procal for everyone worth it? especially when
1) we know less duration is better
2) no difference in outcomes
3) multiple studies show *more* abx when you use PCT.
ADAPT-Sepsis results from CCR Down Under.
1ry outcomes: Standard care vs PCT shows improved significant reduction in antibiotic duration, but not for Standard vs CRP.
No difference in 90D mortality.
#CCRdownunder24
1ry outcomes: Standard care vs PCT shows improved significant reduction in antibiotic duration, but not for Standard vs CRP.
No difference in 90D mortality.
#CCRdownunder24
December 9, 2024 at 10:42 PM
One of few trials to show a difference for PCT. But is it worth it? They saved a day of abx (8.1d vs 7d PCT vs SoC) 🤷♂️
Is the cost of procal for everyone worth it? especially when
1) we know less duration is better
2) no difference in outcomes
3) multiple studies show *more* abx when you use PCT.
Is the cost of procal for everyone worth it? especially when
1) we know less duration is better
2) no difference in outcomes
3) multiple studies show *more* abx when you use PCT.
Reposted by Patrick Bafuma PA-C
ABGs are one of the most overused and medically unnecessary tests.
December 9, 2024 at 9:20 PM
ABGs are one of the most overused and medically unnecessary tests.
Reposted by Patrick Bafuma PA-C
in @jaccjournals.bsky.social meta-analysis comparing AVR vs clinical surveillance for asymptomatic patients with severe AS
Bottom line : no differences in all-cause or CV deaths, reduction in HF hospitalization and strokes
www.sciencedirect.com/science/arti...
#cardiosky
some thoughts ⬇️
Bottom line : no differences in all-cause or CV deaths, reduction in HF hospitalization and strokes
www.sciencedirect.com/science/arti...
#cardiosky
some thoughts ⬇️
Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis
Current guidelines recommend a strategy of clinical surveillance (CS) for patients with asymptomatic severe aortic stenosis (AS) and a normal left ven…
www.sciencedirect.com
December 8, 2024 at 9:43 PM
in @jaccjournals.bsky.social meta-analysis comparing AVR vs clinical surveillance for asymptomatic patients with severe AS
Bottom line : no differences in all-cause or CV deaths, reduction in HF hospitalization and strokes
www.sciencedirect.com/science/arti...
#cardiosky
some thoughts ⬇️
Bottom line : no differences in all-cause or CV deaths, reduction in HF hospitalization and strokes
www.sciencedirect.com/science/arti...
#cardiosky
some thoughts ⬇️
Had an attending once make a reference to "the three S's of neurocritical care"
Sodium
Seizures
See-O2
I think about this way more often than I should
#neurocrit #emimcc
Sodium
Seizures
See-O2
I think about this way more often than I should
#neurocrit #emimcc
December 8, 2024 at 11:57 PM
Had an attending once make a reference to "the three S's of neurocritical care"
Sodium
Seizures
See-O2
I think about this way more often than I should
#neurocrit #emimcc
Sodium
Seizures
See-O2
I think about this way more often than I should
#neurocrit #emimcc
"Congratulations! You put stop times on 300 abx courses, saving over 5000 exposure says"
Spotify wrapped, but for antibiotics. What’s yours?
December 8, 2024 at 9:42 PM
"Congratulations! You put stop times on 300 abx courses, saving over 5000 exposure says"