Pablo Rivera Mejías
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parime.bsky.social
Pablo Rivera Mejías
@parime.bsky.social
Chilean scientist exploring mitochondrial proteome homeostasis using (functional) proteomics at the @embl.org. Bridging Excellence Fellow EMBL|Stanford Life Science Alliance.
Reposted by Pablo Rivera Mejías
We are just one seminar in, and the Metabolism in Development & Physiology series is already fantastic! If you would like to join our community and share your research, please apply for a talk 😊
💥Call for Speakers💥
Hey metabolism enthusiasts!
Do you, or someone you know, dive into the fascinating world of metabolism?
🔬 We are seeking speakers for the Metabolism in Development & Physiology seminars! Showcase your work & connect with our community!
👉 Apply at:
docs.google.com/forms/d/e/1F...
Apply to give a talk on Metabolism in Development and Physiology
docs.google.com
November 18, 2025 at 3:53 PM
Reposted by Pablo Rivera Mejías
Join us later today 👇
Join us for Journal Club tomorrow, November 12th, as Dr. Elias Adriaenssens presents his recently published article in Nature Cell Biology, titled “Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery.”

We look forward to seeing you there!
November 12, 2025 at 6:04 AM
Just finished last week the @embolableadership.bsky.social course—3 days of practical tips and new perspectives on leading in science. Highly recommend for postdocs or anyone moving into science leadership. Besides the course, the @embo.org poster collection from past meetings is amazing!
November 10, 2025 at 1:48 PM
Check out the new publication from our lab, led by the amazing @kejiali.bsky.social. Really a breakthrough for the exploration of protein-ligand interactions.
Finally out! 🤩 Check out our HT- PELSA for high throughput screening!
Happy to see our HT-PELSA paper now published in @natsmb.nature.com 🎊 Big thanks for the constructive review process! 📖Read the manuscript here (www.nature.com/articles/s41...) & check the thread for additional information ⬇️
November 6, 2025 at 7:51 AM
Reposted by Pablo Rivera Mejías
🔜Only one week to go 🎉! Looking forward to hosting the inaugural talks of our “Metabolism in Development & Physiology” seminar series. Join us by registering here: forms.gle/Y8QzucogKKrZ...
We’re excited for our very first “Metabolism in Development & Physiology” seminar next week!
🗓 13 Nov 2025, 16:00 CET
🎙 Alexander Aulehla (EMBL Heidelberg)
🎙 Christopher Bell (Uni of Oxford)
Register here to join the the talks: forms.gle/Y8QzucogKKrZ...
November 3, 2025 at 2:18 PM
Reposted by Pablo Rivera Mejías
We are #hiring for a Tenure Track Assistant Professor position in the Department of Molecular&Cellular Physiology (med.stanford.edu/mcp.html) at @stanfordmedicine.bsky.social. Please apply or forward the opportunity to anybody who might be interested.
facultypositions.stanford.edu/en-us/job/49...
Stanford | Faculty Positions: Details - Assistant Professor of Molecular and Cellular Physiology
facultypositions.stanford.edu
October 29, 2025 at 5:13 PM
I recently read Byung-Chul Han’s The Crisis of Narration, whose reflections on contemporary society also resonate with modern science. The shortage of new, disruptive theories in biology may stem from the dominance of data-driven research—a provocative idea worth considering.
October 28, 2025 at 9:48 PM
Reposted by Pablo Rivera Mejías
We are thrilled to announce the inaugural Metabolism in Development & Physiology virtual seminar, a new series connecting researchers across all stages & disciplines in metabolism!

🗓 13 Nov 2025, 16:00 CET
🎙 Alexander Aulehla (EMBL Heidelberg), &
🎙 Christopher Bell (Uni of Oxford)

See you there!
October 28, 2025 at 4:13 PM
Reposted by Pablo Rivera Mejías
Hot off the press! Our paper, “Global comparative structural analysis of responses to protein phosphorylation”, is now out in Nature Communications!

www.nature.com/articles/s41...
Global comparative structural analysis of responses to protein phosphorylation - Nature Communications
Phosphorylation is central to protein regulation, yet its structural mechanisms remain poorly understood. Here, the authors conduct a global, systematic analysis of phosphorylated versus non-phosphory...
www.nature.com
October 27, 2025 at 10:29 AM
Reposted by Pablo Rivera Mejías
Precisely mapping proteases specificity and predicting cleavage rates - with peptide libraries: doi.org/10.1101/2025.... This is a powerful application that is uniquely enabled by the peptidoform confidence and QuantUMS modules in DIA-NN 2.0.
October 7, 2025 at 12:33 PM
Reposted by Pablo Rivera Mejías
My new lab at the MPI Age is looking for a postdoc in skeletal muscle cell and molecular biology! If you’re a curious and motivated scientist and would like to apply, check the details below:
🚨 Job alert! The Fernandes Lab is looking for a postdoc (m/f/d)! Apply now!

mpi-age.de.umantis.com/Vacancies/49...

@stephalcantara.bsky.social @cecad.bsky.social
September 11, 2025 at 11:19 AM
Reposted by Pablo Rivera Mejías
My PhD student @leonielorenz.bsky.social (with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology:
www.ebi.ac.uk/training/onl...

Including both molecular and epidemiological examples
Mathematical modelling for biologists - Modelling concepts in biological research
Mathematical modelling for biologists - Modelling concepts in biological research
www.ebi.ac.uk
August 15, 2025 at 10:39 AM
"If I cannot build it, I do not understand it."
A brilliant piece led by @elias-adriaenssens.bsky.social shedding light on the fundamental rules of transmembrane cargo receptors involved in selective autophagy. A must-read for anyone in the mitochondrial PQC field.
And it's out!

I'm thrilled to share our new paper (Adriaenssens et al., Nat Cell Biol 2025).

This paper describes a new mechanism for the initiation of autophagosome biogenesis.

We found that this WIPI-ATG13-driven pathway is preferentially used by a group of transmembrane autophagy receptors.
August 1, 2025 at 8:12 AM
Reposted by Pablo Rivera Mejías
‼️ We're looking for a postdoc to join our team starting January 1st, 2026! ‼️
Are you curious about how exercise promotes positive changes at the molecular level in obesity and diabetes? If so, consider applying or reach out with any questions.

ddz.de/job/postdoct...

ddz.de/en/research/...
Postdoctoral Researcher (Ph.D./Dr. rer. nat., m/f/div., E13 TV-L, 100%) - Deutsches Diabetes-Zentrum (DDZ)
Institut für Klinische Biochemie und Pathobiochemie (Direktor: Univ.-Prof. Dr. rer. nat. Hadi Al-Hasani), Nachwuchsforschungsgruppe Crosstalk (Leiterin: Melanie Mittenbühler, Dr.) (25019)
ddz.de
July 30, 2025 at 10:53 AM
Reposted by Pablo Rivera Mejías
A big day for preventing mitochondrial diseases from transmitting to the next generation
www.nature.com/articles/d41...
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
July 17, 2025 at 1:25 AM
Reposted by Pablo Rivera Mejías
Big congrats to everyone involved - it was a blast! 🎊 If you're interested in #multiomics integration or #kidneyfibrosis, check it out! ⬇️
The final version of our multi-omics study on kidney fibrosis is out now (tinyurl.com/kidneyfibMSB). Together w/ Pepperkok + Savitski labs @embl.org, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis
July 4, 2025 at 7:18 AM
Reposted by Pablo Rivera Mejías
I love this display of the trade-off offered by short separation times.

𝐈𝐭 𝐫𝐞𝐟𝐥𝐞𝐜𝐭𝐬 𝐭𝐡𝐞 𝐟𝐮𝐧𝐝𝐚𝐦𝐞𝐧𝐭𝐚𝐥 𝐫𝐨𝐥𝐞 𝐭𝐡𝐚𝐭 𝐬𝐞𝐩𝐚𝐫𝐚𝐭𝐢𝐨𝐧 𝐩𝐥𝐚𝐲𝐬 𝐟𝐨𝐫 𝐝𝐞𝐞𝐩 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐚𝐧𝐚𝐥𝐲𝐬𝐢𝐬: www.nature.com/articles/s41...

Short separation times allow analyzing more samples per day (SPD) but sacrifice coverage.

1/2
June 8, 2025 at 1:09 PM
Reposted by Pablo Rivera Mejías
We're Hiring! Join our dynamic, international team at Helmholtz Munich as a Lab Technician. We provide dynamic and young environment.
English and German language skills required

Apply here: jobs.helmholtz-muenchen.de/jobposting/f...
Lab Technician (f/m/x)
jobs.helmholtz-muenchen.de
May 9, 2025 at 1:32 PM
Reposted by Pablo Rivera Mejías
The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉
You can find the full story here www.science.org/doi/10.1126/...
@verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 6:20 PM
Reposted by Pablo Rivera Mejías
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 17, 2025 at 6:43 PM
Such fantastic work! I had the luck to see this at the past mito meeting in Sitges. A great example of multidisciplinary work uncovering how spontaneous physical changes play a central role in nucleoid distribution in mitochondria. Congrats @jclandoni.bsky.social!
Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
December 26, 2024 at 12:02 PM
Amazing mechanism! Hyperpromiscuous phage kinase to overcome bacterial defenses. Great work from the always successful combo of the Savitski Lab and @typaslab.bsky.social.
1/11 - With Karin Mitosch and Clément Potel + colleagues in Savitski lab and @typaslab.bsky.social @embl.org, I’m very happy to share our discovery of a hyper-promiscuous phage protein kinase (T7K) which broadly deactivates bacterial defenses! 🦠
www.biorxiv.org/content/10.1...
December 23, 2024 at 3:13 PM
Reposted by Pablo Rivera Mejías
#StarterPack for the #Mitochondria research community! Very much a work in progress, comment below/reach out to be added!

#Mito #Mitochondriac

go.bsky.app/J6Bu5fL
November 12, 2024 at 6:35 PM
Reposted by Pablo Rivera Mejías
This image shows individual mitochondria in different colours.

Each cluster of mitochondria represents a cell, in this case a type of white blood cell known as a macrophage 🧪🔬
December 18, 2024 at 9:39 AM
Reposted by Pablo Rivera Mejías
Hi Bluesky community! 👋

Are you looking forward to 2025 as much as we are? 👀

We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!

➡️ s.embl.org/poster-bl

#EMBLEvents #molecularbiology #lifesciencetraining
December 13, 2024 at 9:06 AM