Dr Mark Nixon
@nixon-lab.bsky.social
Research Fellow at Centre for Cardiovascular Science, University of Edinburgh. Investigating glucocorticoid action in cardiometabolic disease. Views my own
Website:
http://www.edinburghmetabolism.co.uk/mark-nixon
ORCID: 0000-0001-5437-3724
Website:
http://www.edinburghmetabolism.co.uk/mark-nixon
ORCID: 0000-0001-5437-3724
Pinned
Dr Mark Nixon
@nixon-lab.bsky.social
· Jan 10
The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
Nature Communications - Corticosteroid binding globulin modulates circulating glucocorticoids, but its metabolic implications remain unclear. Here, the authors show that CBG regulators neutrophil...
rdcu.be
Years of collaborative work, fuelled by cortisol (and coffee!), but I'm thrilled to share our passion project on neutrophil elastase-mediated regulation of adipose glucocorticoid action has finally been published in @naturecomms.bsky.social
rdcu.be/d5Mk8
rdcu.be/d5Mk8
Reposted by Dr Mark Nixon
The next LIPID MAPS #webinar is next week... if you haven't registered for this month's #webinar, titled: 'From Circulation to Cell: Steroid Trafficking in Cardiometabolic Health and Disease' with Mark Nixon, you can register here now: bit.ly/3YpTJlf
May 19, 2025 at 7:49 AM
The next LIPID MAPS #webinar is next week... if you haven't registered for this month's #webinar, titled: 'From Circulation to Cell: Steroid Trafficking in Cardiometabolic Health and Disease' with Mark Nixon, you can register here now: bit.ly/3YpTJlf
Reposted by Dr Mark Nixon
The time is now to register! Early Bird Registration Deadline is May 1st, 2025, for the #AdiposeBiology Conference happening in Montreal, Quebec, Aug 19 & 20th, 2025.
Go to: www.adiposebiology.com to secure your spot today!
#ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
Go to: www.adiposebiology.com to secure your spot today!
#ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
April 25, 2025 at 3:51 PM
The time is now to register! Early Bird Registration Deadline is May 1st, 2025, for the #AdiposeBiology Conference happening in Montreal, Quebec, Aug 19 & 20th, 2025.
Go to: www.adiposebiology.com to secure your spot today!
#ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
Go to: www.adiposebiology.com to secure your spot today!
#ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
Great to be back at #SfEBES2025!
After a few years away, it’s fantastic to return to such a dynamic and supportive endocrine event by @socendocrinology.bsky.social. The advances being made in both basic research and clinical care are a real inspiration to get back to the lab!
After a few years away, it’s fantastic to return to such a dynamic and supportive endocrine event by @socendocrinology.bsky.social. The advances being made in both basic research and clinical care are a real inspiration to get back to the lab!
March 11, 2025 at 10:27 AM
Great to be back at #SfEBES2025!
After a few years away, it’s fantastic to return to such a dynamic and supportive endocrine event by @socendocrinology.bsky.social. The advances being made in both basic research and clinical care are a real inspiration to get back to the lab!
After a few years away, it’s fantastic to return to such a dynamic and supportive endocrine event by @socendocrinology.bsky.social. The advances being made in both basic research and clinical care are a real inspiration to get back to the lab!
Reposted by Dr Mark Nixon
Grants for ESE Summer School 2025 close in one week - 6 March!
Join us in Innsbruck, Austria 22-25 June 2025.
Grow as a scientist while making friends across Europe in #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
👉https://ow.ly/cWmJ50UXIRe
Join us in Innsbruck, Austria 22-25 June 2025.
Grow as a scientist while making friends across Europe in #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
👉https://ow.ly/cWmJ50UXIRe
February 27, 2025 at 11:43 AM
Grants for ESE Summer School 2025 close in one week - 6 March!
Join us in Innsbruck, Austria 22-25 June 2025.
Grow as a scientist while making friends across Europe in #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
👉https://ow.ly/cWmJ50UXIRe
Join us in Innsbruck, Austria 22-25 June 2025.
Grow as a scientist while making friends across Europe in #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
👉https://ow.ly/cWmJ50UXIRe
What a fantastic day at the Scottish Cardiovascular Forum 2025! It was great to catch up with some familiar faces and have the opportunity to connect with new colleagues, all while discussing some of the wonderful cardiovascular research taking place in Scotland.
#SCF2025 #CardiovascularResearch
#SCF2025 #CardiovascularResearch
February 23, 2025 at 9:41 AM
What a fantastic day at the Scottish Cardiovascular Forum 2025! It was great to catch up with some familiar faces and have the opportunity to connect with new colleagues, all while discussing some of the wonderful cardiovascular research taking place in Scotland.
#SCF2025 #CardiovascularResearch
#SCF2025 #CardiovascularResearch
Reposted by Dr Mark Nixon
🚨THIS WEEKEND please join me & the @thebhf.bsky.social in inspiring the nation to learn LIFE SAVING CPR❤️🙏
450,000 people have now engaged with the FREE online training course to learn CPR in JUST 15 MINUTES!
Lets be ready to save a life
www.bhf.org.uk/how-you-can-...
450,000 people have now engaged with the FREE online training course to learn CPR in JUST 15 MINUTES!
Lets be ready to save a life
www.bhf.org.uk/how-you-can-...
February 21, 2025 at 10:02 AM
🚨THIS WEEKEND please join me & the @thebhf.bsky.social in inspiring the nation to learn LIFE SAVING CPR❤️🙏
450,000 people have now engaged with the FREE online training course to learn CPR in JUST 15 MINUTES!
Lets be ready to save a life
www.bhf.org.uk/how-you-can-...
450,000 people have now engaged with the FREE online training course to learn CPR in JUST 15 MINUTES!
Lets be ready to save a life
www.bhf.org.uk/how-you-can-...
Reposted by Dr Mark Nixon
ESE Summer School 2025 is now open for registration! Innsbruck, Austria 22-25 June 2025.
Grants available.
Grow as a scientist while making friends across Europe in the field of #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
ow.ly/cWmJ50UXIRe
Grants available.
Grow as a scientist while making friends across Europe in the field of #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
ow.ly/cWmJ50UXIRe
February 12, 2025 at 9:50 AM
ESE Summer School 2025 is now open for registration! Innsbruck, Austria 22-25 June 2025.
Grants available.
Grow as a scientist while making friends across Europe in the field of #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
ow.ly/cWmJ50UXIRe
Grants available.
Grow as a scientist while making friends across Europe in the field of #endocrinology.
📅 Early Bird deadline: 20 May 2025.
Register today!
ow.ly/cWmJ50UXIRe
Reposted by Dr Mark Nixon
Weekend reading! Our latest Review discusses novel pharmacological approaches to lowering blood pressure and managing #hypertension: rdcu.be/d82w9
Novel pharmacological approaches to lowering blood pressure and managing hypertension
Nature Reviews Cardiology - Hypertension is the leading cause of death globally but has low rates of diagnosis and treatment. In this Review, Dhaun and colleagues discuss the reasons for poor...
rdcu.be
February 7, 2025 at 8:17 PM
Weekend reading! Our latest Review discusses novel pharmacological approaches to lowering blood pressure and managing #hypertension: rdcu.be/d82w9
Reposted by Dr Mark Nixon
A very innovative approach to cancer: engineering fat cells to convert to beige fat to starve tumors, outcompeting 5 types of cancer in experimental models
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
Implantation of engineered adipocytes suppresses tumor progression in cancer models - Nature Biotechnology
Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.
www.nature.com
February 4, 2025 at 2:56 PM
A very innovative approach to cancer: engineering fat cells to convert to beige fat to starve tumors, outcompeting 5 types of cancer in experimental models
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
www.nature.com/articles/s41... @naturebiotech.bsky.social y.social @nadavahituv.bsky.social tuv.bsky.social
Reposted by Dr Mark Nixon
Spatial multi-omics has just gone to the next level!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
—Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm
—"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
—Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm
—"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"
January 27, 2025 at 11:26 PM
Spatial multi-omics has just gone to the next level!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
—Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm
—"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
—Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm
—"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"
Reposted by Dr Mark Nixon
The abstract submission deadline is only ONE WEEK away!
Contribute to the Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and ESE 2025 and share your research with the #endocrine community.
Submit your abstract by 3 February.
👉 bit.ly/3PXTqcB
Contribute to the Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and ESE 2025 and share your research with the #endocrine community.
Submit your abstract by 3 February.
👉 bit.ly/3PXTqcB
January 27, 2025 at 8:29 AM
The abstract submission deadline is only ONE WEEK away!
Contribute to the Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and ESE 2025 and share your research with the #endocrine community.
Submit your abstract by 3 February.
👉 bit.ly/3PXTqcB
Contribute to the Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and ESE 2025 and share your research with the #endocrine community.
Submit your abstract by 3 February.
👉 bit.ly/3PXTqcB
Our latest publication is now out in Cardiovascular Diabetology as part of a special collection on Perivascular Adipose Tissue!
🐭 💓 ♂️ ♀️ "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones"
cardiab.biomedcentral.com/articles/10....
🐭 💓 ♂️ ♀️ "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones"
cardiab.biomedcentral.com/articles/10....
January 27, 2025 at 1:25 PM
Our latest publication is now out in Cardiovascular Diabetology as part of a special collection on Perivascular Adipose Tissue!
🐭 💓 ♂️ ♀️ "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones"
cardiab.biomedcentral.com/articles/10....
🐭 💓 ♂️ ♀️ "Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones"
cardiab.biomedcentral.com/articles/10....
Reposted by Dr Mark Nixon
Health misinformation is everywhere — but we’re here to set the record straight! Our award-winning podcast reveals how hormones impact all our lives. Give it a listen 🎧 ow.ly/XaY450ULTUe
Thanks to @katarney.bsky.social, first create the media, and all our experts!
Thanks to @katarney.bsky.social, first create the media, and all our experts!
January 23, 2025 at 3:32 PM
Health misinformation is everywhere — but we’re here to set the record straight! Our award-winning podcast reveals how hormones impact all our lives. Give it a listen 🎧 ow.ly/XaY450ULTUe
Thanks to @katarney.bsky.social, first create the media, and all our experts!
Thanks to @katarney.bsky.social, first create the media, and all our experts!
Reposted by Dr Mark Nixon
Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
GLP-1 and the Neurobiology of Eating Control: Recent Advances
Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af
academic.oup.com
January 21, 2025 at 11:59 AM
Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
Some birthday celebrations in the lab over the past few days for our wonderful Postdoc Mhairi - double celebration as Mhairi has also just published her main PhD paper on Wnt signalling in HFpEF. Congratulations Mhairi!
bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
January 20, 2025 at 8:27 AM
Some birthday celebrations in the lab over the past few days for our wonderful Postdoc Mhairi - double celebration as Mhairi has also just published her main PhD paper on Wnt signalling in HFpEF. Congratulations Mhairi!
bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Dr Mark Nixon
Promising new cell therapy for liver disease shows positive results! Results from the MATCH trial, run by Stuart Forbes' lab in the Centre for Regenerative Medicine, were published in @nature.com Medicine today
regeneration-repair.ed.ac.uk/promising-ne...
regeneration-repair.ed.ac.uk/promising-ne...
January 10, 2025 at 4:35 PM
Promising new cell therapy for liver disease shows positive results! Results from the MATCH trial, run by Stuart Forbes' lab in the Centre for Regenerative Medicine, were published in @nature.com Medicine today
regeneration-repair.ed.ac.uk/promising-ne...
regeneration-repair.ed.ac.uk/promising-ne...
Years of collaborative work, fuelled by cortisol (and coffee!), but I'm thrilled to share our passion project on neutrophil elastase-mediated regulation of adipose glucocorticoid action has finally been published in @naturecomms.bsky.social
rdcu.be/d5Mk8
rdcu.be/d5Mk8
The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure
Nature Communications - Corticosteroid binding globulin modulates circulating glucocorticoids, but its metabolic implications remain unclear. Here, the authors show that CBG regulators neutrophil...
rdcu.be
January 10, 2025 at 2:27 PM
Years of collaborative work, fuelled by cortisol (and coffee!), but I'm thrilled to share our passion project on neutrophil elastase-mediated regulation of adipose glucocorticoid action has finally been published in @naturecomms.bsky.social
rdcu.be/d5Mk8
rdcu.be/d5Mk8
Reposted by Dr Mark Nixon
www.jacc.org/doi/10.1016/...
A very proud moment to see this labour of love published in @jaccjournals.bsky.social @jaccedge.bsky.social
Most of my Co-authors have not made it over from the other place, but I’m so grateful to them as well as the patients who had faith in the study to take part
A very proud moment to see this labour of love published in @jaccjournals.bsky.social @jaccedge.bsky.social
Most of my Co-authors have not made it over from the other place, but I’m so grateful to them as well as the patients who had faith in the study to take part
Myocardial Fibroblast Activation After Acute Myocardial Infarction: A Positron Emission Tomography and Magnetic Resonance Study
www.jacc.org
January 8, 2025 at 7:03 PM
www.jacc.org/doi/10.1016/...
A very proud moment to see this labour of love published in @jaccjournals.bsky.social @jaccedge.bsky.social
Most of my Co-authors have not made it over from the other place, but I’m so grateful to them as well as the patients who had faith in the study to take part
A very proud moment to see this labour of love published in @jaccjournals.bsky.social @jaccedge.bsky.social
Most of my Co-authors have not made it over from the other place, but I’m so grateful to them as well as the patients who had faith in the study to take part
Reposted by Dr Mark Nixon
Interested in how maternal stress affects the offspring’s brain? Come and do a PhD with us in beautiful Edinburgh. More info here: www.findaphd.com/phds/project...
a drawing of a brain with a rainbow and a blue one
ALT: a drawing of a brain with a rainbow and a blue one
media.tenor.com
December 9, 2024 at 2:12 PM
Interested in how maternal stress affects the offspring’s brain? Come and do a PhD with us in beautiful Edinburgh. More info here: www.findaphd.com/phds/project...
Reposted by Dr Mark Nixon
3rd Day of Research: Three new centre Directors 🎉
We welcomed Prof Andrew Horne as new Director of the Centre for Reproductive Health, and Prof Tilo Kunath and Prof Anna Williams as new Co-Directors for the Centre for Regenerative Medicine.
📰: edin.ac/3ZCwhSG
edin.ac/3O6z14p
#12DaysOfResearch
We welcomed Prof Andrew Horne as new Director of the Centre for Reproductive Health, and Prof Tilo Kunath and Prof Anna Williams as new Co-Directors for the Centre for Regenerative Medicine.
📰: edin.ac/3ZCwhSG
edin.ac/3O6z14p
#12DaysOfResearch
December 9, 2024 at 10:26 AM
3rd Day of Research: Three new centre Directors 🎉
We welcomed Prof Andrew Horne as new Director of the Centre for Reproductive Health, and Prof Tilo Kunath and Prof Anna Williams as new Co-Directors for the Centre for Regenerative Medicine.
📰: edin.ac/3ZCwhSG
edin.ac/3O6z14p
#12DaysOfResearch
We welcomed Prof Andrew Horne as new Director of the Centre for Reproductive Health, and Prof Tilo Kunath and Prof Anna Williams as new Co-Directors for the Centre for Regenerative Medicine.
📰: edin.ac/3ZCwhSG
edin.ac/3O6z14p
#12DaysOfResearch
Reposted by Dr Mark Nixon
I'm thrilled to co-organize the inaugural #AdiposeBiology conference with Jacqueline Beaudry, Hoon-Ki Sung, and @sablesys.bsky.social!
📍Montreal, Canada
📅 August 19-20, 2025
Registration opens Jan 1, 2025. Mor info in the coming weeks.
Hope to see you there! @AdiposeBiology #AdiposeBiology2025
📍Montreal, Canada
📅 August 19-20, 2025
Registration opens Jan 1, 2025. Mor info in the coming weeks.
Hope to see you there! @AdiposeBiology #AdiposeBiology2025
November 30, 2024 at 11:15 AM
I'm thrilled to co-organize the inaugural #AdiposeBiology conference with Jacqueline Beaudry, Hoon-Ki Sung, and @sablesys.bsky.social!
📍Montreal, Canada
📅 August 19-20, 2025
Registration opens Jan 1, 2025. Mor info in the coming weeks.
Hope to see you there! @AdiposeBiology #AdiposeBiology2025
📍Montreal, Canada
📅 August 19-20, 2025
Registration opens Jan 1, 2025. Mor info in the coming weeks.
Hope to see you there! @AdiposeBiology #AdiposeBiology2025
Reposted by Dr Mark Nixon
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Method of the Year 2024: spatial proteomics - Nature Methods
Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.
www.nature.com
December 6, 2024 at 8:52 PM
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Reposted by Dr Mark Nixon
@lifemetabolism.bsky.social is now indexed on PMC. Come on down and check out our great content. Please share and repost.
December 5, 2024 at 10:36 AM
@lifemetabolism.bsky.social is now indexed on PMC. Come on down and check out our great content. Please share and repost.
Reposted by Dr Mark Nixon
Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction & obesity: a secondary analysis of the SUMMIT trial @natureportfolio.bsky.social 🥼🔬👩🔬👨🔬.
#cardiovascular #cardiosky #obesity #heartfailure #MedSky 👇👇
www.nature.com/articles/s41...
#cardiovascular #cardiosky #obesity #heartfailure #MedSky 👇👇
www.nature.com/articles/s41...
Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial - Nature Medicine
In a mechanistic analysis of the SUMMIT trial that tested tirzepatide in patients with heart failure with preserved ejection fraction and obesity, treatment with this dual glucagon-like peptide-1 rece...
www.nature.com
November 21, 2024 at 7:16 PM
Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction & obesity: a secondary analysis of the SUMMIT trial @natureportfolio.bsky.social 🥼🔬👩🔬👨🔬.
#cardiovascular #cardiosky #obesity #heartfailure #MedSky 👇👇
www.nature.com/articles/s41...
#cardiovascular #cardiosky #obesity #heartfailure #MedSky 👇👇
www.nature.com/articles/s41...
Reposted by Dr Mark Nixon
The Human Cell Atlas is yielding detailed maps of human tissues and systems throughout life, along with methods to handle single-cell data. Four scientists reflect in Nature on how the project is transforming our understanding of human biology. 🧪
Cellular atlases are unlocking the mysteries of the human body
Scientists reflect on insights from the Human Cell Atlas.
go.nature.com
November 26, 2024 at 3:06 PM
The Human Cell Atlas is yielding detailed maps of human tissues and systems throughout life, along with methods to handle single-cell data. Four scientists reflect in Nature on how the project is transforming our understanding of human biology. 🧪