Really proud and excited to share the final version of our paper, co-led by the Bluesky-less Munib Hasnain!!

We asked whether cognitive and motor neural dynamics can be isolated from one another, or whether they’re driven by common neural mechanisms 1/n

www.nature.com/articles/s41...

The #habenula in our brain tells us about the negative consequences of our actions, helping us avoid risky behaviors and problems with #addiction. My colleagues found neural pathways to the habenula that promoted consistency in the behavior of mice making risky or safe choices.

rdcu.be/d7g8d

Great start of the new year!
A new manuscript just published showing yet again how design principles and strategies from biological perceptive systems enable robust processing on analog #neuromorphic electronic systems, despite their variability!
rdcu.be/d5o0d

Cutting it a bit fine, but here’s my review of the year in neuroscience for 2024

The eighth of these, would you believe? We’ve got dark neurons, tiny monkeys, the most complete brain wiring diagram ever constructed, and much more…
Published on The Spike

Enjoy!

medium.com/the-spike/20...

GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments

www.pnas.org/doi/10.1073/...

Fantastic journey through the history of hippocampal extra cellular recording techniques and the search for cell assemblies by Bruce McNaughton.

onlinelibrary.wiley.com/doi/10.1002/...

𝗧𝗵𝗲 𝗰𝗹𝗮𝘂𝘀𝘁𝗿𝘂𝗺 𝗮𝗻𝗱 𝘀𝘆𝗻𝗰𝗵𝗿𝗼𝗻𝗶𝘇𝗲𝗱 𝗯𝗿𝗮𝗶𝗻 𝘀𝘁𝗮𝘁𝗲𝘀
This is looking like a must read!
doi.org/10.1016/j.ti...
#neuroscience

Thrilled to present our latest BioRXiv on brain/body interactions during defensive freezing behaviour! (www.biorxiv.org/content/10.1...). You might think that a frozen animal has, well, frozen muscle activity, right? Wrong! Underneath the still surface of a fly, something in the legs is beating… 🧵

Together with some friends we built an optical Brain Machine Interface to see if cortical activity (PPC) can control behaviour in real time, without animals having to learn to use it. Here's what happened:

www.biorxiv.org/content/10.1...

🔵 blue spot alert: Anita Luethi's team reports a dual role of #locuscoeruleus in #sleep in Nature Neuroscience @natureportfolio.bsky.social

1) high LC activity facilitates cortical microarousals
2) low LC activity is required for NREMS-to-REMS transitions

doi.org/10.1038/s415...

The main output of the hippocampus is subcortical.
Today, for the last class on the neurophys of navigation & mem, we will discuss this fantastic paper by @davidtingley.bsky.social (Buzsaki Lab) showing a link btw hippocampal sharp wave-ripples & glucose release.

www.nature.com/articles/s41...

1/n

Thrilled that our paper on the role of the rat prelimbic cortex (PLC) in decision making is finally out! Three main findings are described in this thread

Co-authors: Jensen Palmer, Samantha White, and Kevin Chavez Lopez

doi.org/10.1523/JNEU...