Cristina Popa
@nephroseeker.medsky.social
🩺 Nephrologist = kidney philosopher
📜History lover
🕊️ Aspiring to be better. Freethinker
📍 #NephJC executive editor
📍@KIreportsbsky.social
📍ERAkidney #ERA25 social media co-leader
#NephSky #MedSky
📜History lover
🕊️ Aspiring to be better. Freethinker
📍 #NephJC executive editor
📍@KIreportsbsky.social
📍ERAkidney #ERA25 social media co-leader
#NephSky #MedSky
Reposted by Cristina Popa
Whoah
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 13, 2025 at 11:05 PM
Whoah
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
EBV not only causes multiple sclerosis, it also might be the root of SLE
www.science.org/doi/10.1126/...
An EBV vaccine to rid ourselves of these horrible autoimmune conditions (and many cancers)?
#lupus #medsky #RheumSky
@christosargyrop.bsky.social
Reposted by Cristina Popa
16 is same as last year
someone check if I have missed anything
Read our blogs here www.nephjc.com/news/kidneyw...
#NephJC #KidneyWk
@nephroseeker.medsky.social @brendonneuen.bsky.social
someone check if I have missed anything
Read our blogs here www.nephjc.com/news/kidneyw...
#NephJC #KidneyWk
@nephroseeker.medsky.social @brendonneuen.bsky.social
Kidney Week in Houston: Day 1 — NephJC
in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis
www.nephjc.com
November 9, 2025 at 11:31 PM
16 is same as last year
someone check if I have missed anything
Read our blogs here www.nephjc.com/news/kidneyw...
#NephJC #KidneyWk
@nephroseeker.medsky.social @brendonneuen.bsky.social
someone check if I have missed anything
Read our blogs here www.nephjc.com/news/kidneyw...
#NephJC #KidneyWk
@nephroseeker.medsky.social @brendonneuen.bsky.social
Reposted by Cristina Popa
November 8, 2025 at 5:21 PM
Reposted by Cristina Popa
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
November 8, 2025 at 8:27 PM
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
Reposted by Cristina Popa
And another ns-MRA
Balcinrenone added to Dapa in proteinuric CKD
#KidneyWK
@thelancet.com
www.thelancet.com/journals/lan...
Balcinrenone added to Dapa in proteinuric CKD
#KidneyWK
@thelancet.com
www.thelancet.com/journals/lan...
Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinica...
In participants with chronic kidney disease at increased risk of disease progression,
a fixed dose combination of balcinrenone and dapagliflozin was superior to dapagliflozin
alone in reducing albumin...
www.thelancet.com
November 8, 2025 at 6:18 PM
And another ns-MRA
Balcinrenone added to Dapa in proteinuric CKD
#KidneyWK
@thelancet.com
www.thelancet.com/journals/lan...
Balcinrenone added to Dapa in proteinuric CKD
#KidneyWK
@thelancet.com
www.thelancet.com/journals/lan...
Reposted by Cristina Popa
The second sibeprenlimab paper in @nejm.org
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
Sibeprenlimab in IgA Nephropathy — Interim Analysis of a Phase 3 Trial | NEJM
The cytokine A proliferation-inducing ligand (APRIL) is considered a key driver of
the pathogenesis of IgA nephropathy. Sibeprenlimab, a humanized IgG2 monoclonal antibody,
selectively binds to and...
www.nejm.org
November 8, 2025 at 5:03 PM
The second sibeprenlimab paper in @nejm.org
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
Missing all the overwhelming amount of science coming out of #KidneyWk?
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
Kidney Week in Houston: Day 2 — NephJC
in this edition: Fish Oil, GBD, Flozination meta-analysis, CHW intervention in Hispanic/Latino patients, and much more
www.nephjc.com
November 8, 2025 at 3:35 PM
Reposted by Cristina Popa
And the GBD analysis on CKD
From @paddymark.bsky.social and colleagues
www.thelancet.com/journals/lan... in @thelancet.com
#KidneyWk
From @paddymark.bsky.social and colleagues
www.thelancet.com/journals/lan... in @thelancet.com
#KidneyWk
Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023
CKD is a major global health issue, with rising prevalence and increasing importance
as a cause of death and as a risk factor for cardiovascular death. A better understating
of aetiology, appropriate ...
www.thelancet.com
November 8, 2025 at 12:14 AM
And the GBD analysis on CKD
From @paddymark.bsky.social and colleagues
www.thelancet.com/journals/lan... in @thelancet.com
#KidneyWk
From @paddymark.bsky.social and colleagues
www.thelancet.com/journals/lan... in @thelancet.com
#KidneyWk
Reposted by Cristina Popa
And paper 3 from @cervantes-lily1.bsky.social
On adaptation of the Navigate Kidney intervention in @kireports.bsky.social
www.kireports.org/article/S246...
#KidneyWk
On adaptation of the Navigate Kidney intervention in @kireports.bsky.social
www.kireports.org/article/S246...
#KidneyWk
November 8, 2025 at 1:24 AM
And paper 3 from @cervantes-lily1.bsky.social
On adaptation of the Navigate Kidney intervention in @kireports.bsky.social
www.kireports.org/article/S246...
#KidneyWk
On adaptation of the Navigate Kidney intervention in @kireports.bsky.social
www.kireports.org/article/S246...
#KidneyWk
Reposted by Cristina Popa
Check out this new editorial in #ASNJASN and simultaneously published for #KidneyWk: "Redefining Immunosuppression in Older Kidney Transplant Recipients: Reflections on the OPTIMIZE Study."
Read more: kidney.pub/JASN0939
Read more: kidney.pub/JASN0939
November 7, 2025 at 6:30 PM
Check out this new editorial in #ASNJASN and simultaneously published for #KidneyWk: "Redefining Immunosuppression in Older Kidney Transplant Recipients: Reflections on the OPTIMIZE Study."
Read more: kidney.pub/JASN0939
Read more: kidney.pub/JASN0939
📖 A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The LIBERation from AcuTE Dialysis (LIBERATE-D) Randomized Clinical Trial
➡️ Presented today at #KidneyWk
➡️ Free to read online from @jama.com:
ja.ma/4ohVKuK
➡️ Presented today at #KidneyWk
➡️ Free to read online from @jama.com:
ja.ma/4ohVKuK
November 7, 2025 at 6:36 PM
Reposted by Cristina Popa
Don't forget! Tonight is #NephJC night, and it will be a blast 🪩
👋If you're on #KidneyWk, don't be shy, just say hi
✨For tickets, location, and more specifics, see the link 👇👇
www.nephjc.com/news/2025/10...
👋If you're on #KidneyWk, don't be shy, just say hi
✨For tickets, location, and more specifics, see the link 👇👇
www.nephjc.com/news/2025/10...
The 2025 NephJC Night, in Houston — NephJC
SAVE THE DATE! On FRIDAY night, NOVEMBER 7th, NephJC will be hosting another of its legendary NephJC Nights during ASN Kidney Week
www.nephjc.com
November 7, 2025 at 6:25 PM
Don't forget! Tonight is #NephJC night, and it will be a blast 🪩
👋If you're on #KidneyWk, don't be shy, just say hi
✨For tickets, location, and more specifics, see the link 👇👇
www.nephjc.com/news/2025/10...
👋If you're on #KidneyWk, don't be shy, just say hi
✨For tickets, location, and more specifics, see the link 👇👇
www.nephjc.com/news/2025/10...
Reposted by Cristina Popa
Now live in #ASNJASN, simultaneously published with #KidneyWk: "Immunosuppression in Older Kidney Transplant Recipients: A Randomized Controlled Trial"
Read more: kidney.pub/JASN0924
Read more: kidney.pub/JASN0924
November 7, 2025 at 5:30 PM
Now live in #ASNJASN, simultaneously published with #KidneyWk: "Immunosuppression in Older Kidney Transplant Recipients: A Randomized Controlled Trial"
Read more: kidney.pub/JASN0924
Read more: kidney.pub/JASN0924
Rethinking my #KidneyWk FOMO.... If day 1 looked promising, day 2 already has 4 sim pub (see tomorrow's #NephJC newsletter).
✍️🔥Lots of reading and writing to do #Nephsky #Medsky
✍️🔥Lots of reading and writing to do #Nephsky #Medsky
Got #KidneyWk FOMO like @nephroseeker.medsky.social ?
We got you covered with daily coverage of the simultaneous publications!
www.nephjc.com/news/kidneyw...
We got you covered with daily coverage of the simultaneous publications!
www.nephjc.com/news/kidneyw...
Kidney Week in Houston: Day 1 — NephJC
in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis
www.nephjc.com
November 7, 2025 at 6:04 PM
In PISCES, daily n–3 fatty acids cut serious cardiovascular events in dialysis patients by nearly half (HR 0.57). Fish oil clearly had bigger fish to fry than placebo: fewer MIs, strokes, cardiac deaths without extra adverse catches
@nejm.org #kidneywk sim publication
www.nejm.org/doi/full/10....
@nejm.org #kidneywk sim publication
www.nejm.org/doi/full/10....
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | NEJM
Cardiovascular disease is the leading cause of death in patients receiving hemodialysis,
yet effective preventive therapies remain limited. Supplementation with n−3 polyunsaturated
fatty acids, esp...
www.nejm.org
November 7, 2025 at 4:40 PM
In PISCES, daily n–3 fatty acids cut serious cardiovascular events in dialysis patients by nearly half (HR 0.57). Fish oil clearly had bigger fish to fry than placebo: fewer MIs, strokes, cardiac deaths without extra adverse catches
@nejm.org #kidneywk sim publication
www.nejm.org/doi/full/10....
@nejm.org #kidneywk sim publication
www.nejm.org/doi/full/10....
Reposted by Cristina Popa
In the afternoon another late breaking oral session among other things at 4:30 pm
@brendonneuen.bsky.social
Lorundrostat
A new oral GLP1
REMODEL to understand sema mechanism
GBD kidney disease with @paddymark.bsky.social
And
@cervantes-lily1.bsky.social !
#KidneyWk
@brendonneuen.bsky.social
Lorundrostat
A new oral GLP1
REMODEL to understand sema mechanism
GBD kidney disease with @paddymark.bsky.social
And
@cervantes-lily1.bsky.social !
#KidneyWk
November 7, 2025 at 10:39 AM
In the afternoon another late breaking oral session among other things at 4:30 pm
@brendonneuen.bsky.social
Lorundrostat
A new oral GLP1
REMODEL to understand sema mechanism
GBD kidney disease with @paddymark.bsky.social
And
@cervantes-lily1.bsky.social !
#KidneyWk
@brendonneuen.bsky.social
Lorundrostat
A new oral GLP1
REMODEL to understand sema mechanism
GBD kidney disease with @paddymark.bsky.social
And
@cervantes-lily1.bsky.social !
#KidneyWk
Reposted by Cristina Popa
Today’s trials at #KidneyWk
In the morning a LBCT session at 10:30
featuring
PISCES (fish oil in dialysis!)
LIBERATE in AKI
Another AKI alerts from @fperrywilson.bsky.social
A Transplant trial
GLP1 and a Flozin analyses
And
In the morning a LBCT session at 10:30
featuring
PISCES (fish oil in dialysis!)
LIBERATE in AKI
Another AKI alerts from @fperrywilson.bsky.social
A Transplant trial
GLP1 and a Flozin analyses
And
November 7, 2025 at 10:39 AM
Today’s trials at #KidneyWk
In the morning a LBCT session at 10:30
featuring
PISCES (fish oil in dialysis!)
LIBERATE in AKI
Another AKI alerts from @fperrywilson.bsky.social
A Transplant trial
GLP1 and a Flozin analyses
And
In the morning a LBCT session at 10:30
featuring
PISCES (fish oil in dialysis!)
LIBERATE in AKI
Another AKI alerts from @fperrywilson.bsky.social
A Transplant trial
GLP1 and a Flozin analyses
And
Reposted by Cristina Popa
Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself)
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
November 6, 2025 at 6:39 PM
Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself)
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵
Couldn't attend #KidneyWk in person, but ASN uploaded the 1st day plenary session on YouTube 👇
✅Check it out: the president's address, the state-of-the-art lecture by Vlado Perkovic
🎲 High-impact clinical trials: ORIGIN-3 & FINE-ONE
www.youtube.com/watch?v=FMxW...
✅Check it out: the president's address, the state-of-the-art lecture by Vlado Perkovic
🎲 High-impact clinical trials: ORIGIN-3 & FINE-ONE
www.youtube.com/watch?v=FMxW...
Kidney Week 2025: Opening Plenary
YouTube video by American Society of Nephrology
www.youtube.com
November 7, 2025 at 2:30 AM
Couldn't attend #KidneyWk in person, but ASN uploaded the 1st day plenary session on YouTube 👇
✅Check it out: the president's address, the state-of-the-art lecture by Vlado Perkovic
🎲 High-impact clinical trials: ORIGIN-3 & FINE-ONE
www.youtube.com/watch?v=FMxW...
✅Check it out: the president's address, the state-of-the-art lecture by Vlado Perkovic
🎲 High-impact clinical trials: ORIGIN-3 & FINE-ONE
www.youtube.com/watch?v=FMxW...
Reposted by Cristina Popa
We have a new therapy for type 1 diabetes! FINE-ONE with significant proteinuria reduction compared to placebo on a background of RASi with an acceptable safety profile. Where’s the simultaneous pub?? Sglt2 inhibitors are next…#kidneywk
November 6, 2025 at 3:26 PM
We have a new therapy for type 1 diabetes! FINE-ONE with significant proteinuria reduction compared to placebo on a background of RASi with an acceptable safety profile. Where’s the simultaneous pub?? Sglt2 inhibitors are next…#kidneywk
Reposted by Cristina Popa
Application for #NephSIM Nephrons are due 11/13:
A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers
Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘
nephsim.com/nephsim-neph...
A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers
Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘
nephsim.com/nephsim-neph...
November 6, 2025 at 3:05 PM
Application for #NephSIM Nephrons are due 11/13:
A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers
Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘
nephsim.com/nephsim-neph...
A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers
Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘
nephsim.com/nephsim-neph...
Live from #KidneyWk: ORiGIN trial
👉prespecified interim analysis
📉treatment with atacicept resulted in a significantly greater reduction in proteinuria than placebo at week 36 in patients with IgAN
Simultaneous @nejm.org publication 👇👇
www.nejm.org/doi/full/10....
👉prespecified interim analysis
📉treatment with atacicept resulted in a significantly greater reduction in proteinuria than placebo at week 36 in patients with IgAN
Simultaneous @nejm.org publication 👇👇
www.nejm.org/doi/full/10....
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy | NEJM
IgA nephropathy, the most common primary glomerulopathy worldwide, is a kidney disorder of B-cell origin characterized by mesangial accumulation of IgA-containing immune complexes. In at least 50% ...
www.nejm.org
November 6, 2025 at 2:59 PM
Live from #KidneyWk: ORiGIN trial
👉prespecified interim analysis
📉treatment with atacicept resulted in a significantly greater reduction in proteinuria than placebo at week 36 in patients with IgAN
Simultaneous @nejm.org publication 👇👇
www.nejm.org/doi/full/10....
👉prespecified interim analysis
📉treatment with atacicept resulted in a significantly greater reduction in proteinuria than placebo at week 36 in patients with IgAN
Simultaneous @nejm.org publication 👇👇
www.nejm.org/doi/full/10....
While having FOMO for not being at #KidneyWk , looking at the #NephMadness logo for 2026.
Can’t wait for it 🤩
Can’t wait for it 🤩
November 6, 2025 at 2:04 PM
While having FOMO for not being at #KidneyWk , looking at the #NephMadness logo for 2026.
Can’t wait for it 🤩
Can’t wait for it 🤩
Reposted by Cristina Popa
After a 40 minute handa on session where my station worked on kidney US we are back in the lecture room for a talk on lung ultrasound by Nathaniel Reisinger #KidneyWk
November 5, 2025 at 4:10 PM
After a 40 minute handa on session where my station worked on kidney US we are back in the lecture room for a talk on lung ultrasound by Nathaniel Reisinger #KidneyWk
Reposted by Cristina Popa
#NephJC at #KidneyWk
🔥🔥We have all sorts of events
🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun
🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃
For more info 👇👇
www.nephjc.com
🔥🔥We have all sorts of events
🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun
🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃
For more info 👇👇
www.nephjc.com
NephJC
www.nephjc.com
November 5, 2025 at 8:15 PM
#NephJC at #KidneyWk
🔥🔥We have all sorts of events
🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun
🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃
For more info 👇👇
www.nephjc.com
🔥🔥We have all sorts of events
🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun
🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃
For more info 👇👇
www.nephjc.com