@mvfaassen.bsky.social
Reposted
Natural daylight and improved glucose control in Type 2 diabetes
cell.com/cell-metabol...
cell.com/cell-metabol...
Natural daylight during office hours improves glucose control and whole-body substrate metabolism
Harmsen et al. compared the metabolic impact of natural daylight vs. artificial office
lighting in individuals with type 2 diabetes over 5 days. Daylight improved glucose
homeostasis, whole-body fat u...
cell.com
December 18, 2025 at 6:00 PM
Natural daylight and improved glucose control in Type 2 diabetes
cell.com/cell-metabol...
cell.com/cell-metabol...
Reposted
„Further correspondence […] indicates that the authors may have received financial compensation from Monsanto for their work on this article […]. [That] raises significant ethical concerns and calls into question the apparent academic objectivity of the authors in this publication“
December 1, 2025 at 4:12 PM
„Further correspondence […] indicates that the authors may have received financial compensation from Monsanto for their work on this article […]. [That] raises significant ethical concerns and calls into question the apparent academic objectivity of the authors in this publication“
Reposted
„ It appears […] that employees of Monsanto may have contributed to the writing of the article […]. This lack of transparency raises serious ethical concerns regarding […] the academic integrity of the carcinogenicity studies presented.“
December 1, 2025 at 4:09 PM
„ It appears […] that employees of Monsanto may have contributed to the writing of the article […]. This lack of transparency raises serious ethical concerns regarding […] the academic integrity of the carcinogenicity studies presented.“
Reposted
#Oops: The seminal paper that has been used for 25 years to justify that the use of #Glyphosate is safe has been retracted.
▶️ www.sciencedirect.com/science/arti...
"Concerns were raised regarding the authorship of this paper, validity of the research findings…"
▶️ www.sciencedirect.com/science/arti...
"Concerns were raised regarding the authorship of this paper, validity of the research findings…"
December 1, 2025 at 1:11 PM
#Oops: The seminal paper that has been used for 25 years to justify that the use of #Glyphosate is safe has been retracted.
▶️ www.sciencedirect.com/science/arti...
"Concerns were raised regarding the authorship of this paper, validity of the research findings…"
▶️ www.sciencedirect.com/science/arti...
"Concerns were raised regarding the authorship of this paper, validity of the research findings…"
Reposted
Not this again
'however, standard culture methods did not yield readily cultivable microbiota.'
'however, standard culture methods did not yield readily cultivable microbiota.'
The findings of a study in Nature Medicine introduce microbial elements as a component of the brain tumor microenvironment and lay the foundation for future mechanistic and translational studies. go.nature.com/44bO314 #medsky #microbiome 🧪
November 22, 2025 at 8:14 AM
Not this again
'however, standard culture methods did not yield readily cultivable microbiota.'
'however, standard culture methods did not yield readily cultivable microbiota.'
Reposted
Image screening is going to fail. We need audit trails for data provenance.
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 22, 2025 at 4:21 PM
Image screening is going to fail. We need audit trails for data provenance.
Reposted
Interested in Python programming and good software engineering practices? Check out my newest blog post where I introduce a "modern Python" GitHub repository template and talk about my motivation for its creation! mmzdouc.github.io/posts/2025/1...
Modern Python Project GitHub Template
TL;DR: I created a freely available template to facilitate setting up “modern” Python projects.
mmzdouc.github.io
October 22, 2025 at 2:06 PM
Interested in Python programming and good software engineering practices? Check out my newest blog post where I introduce a "modern Python" GitHub repository template and talk about my motivation for its creation! mmzdouc.github.io/posts/2025/1...
Reposted
Also, if you're "in bed with flu", it's almost certainly Covid.
After a long pause, I've just done another England Covid & NHS update as we head into the autumn/winter season.
TLDR: we're in a significant Covid wave now, the NHS is stretched, get boosted if you're eligible.
christinapagel.substack.com/p/england-is...
TLDR: we're in a significant Covid wave now, the NHS is stretched, get boosted if you're eligible.
christinapagel.substack.com/p/england-is...
England is now experiencing a significant Covid wave, after 10 months of relative quiet
The latest Covid situation in England and a look at where NHS services are as we head into winter
christinapagel.substack.com
October 10, 2025 at 1:18 PM
Also, if you're "in bed with flu", it's almost certainly Covid.
Reposted
Finally, we're looking for someone to join our #MassSpec Core Facility to support all the protein/peptide MS & development needs of our research groups utilising:
🧪Protein chemistry
📈Liquid chromatography
⚛️Tandem mass spectrometry
🖥️Data analysis
More at:
www.cruk.manchester.ac.uk/career/mi-25...
🧪Protein chemistry
📈Liquid chromatography
⚛️Tandem mass spectrometry
🖥️Data analysis
More at:
www.cruk.manchester.ac.uk/career/mi-25...
Mass Spec
xkcd.com
October 3, 2025 at 2:17 PM
Finally, we're looking for someone to join our #MassSpec Core Facility to support all the protein/peptide MS & development needs of our research groups utilising:
🧪Protein chemistry
📈Liquid chromatography
⚛️Tandem mass spectrometry
🖥️Data analysis
More at:
www.cruk.manchester.ac.uk/career/mi-25...
🧪Protein chemistry
📈Liquid chromatography
⚛️Tandem mass spectrometry
🖥️Data analysis
More at:
www.cruk.manchester.ac.uk/career/mi-25...
Reposted
We have a potential MRC iCASE PhD with AstraZeneca using mass spectrometric techniques to identify the destination organs of endogenous and exogenous peptide hormones. This should be a really interesting PhD, using both ours and AstraZeneca's expertise and mass spectrometry instrumentation.
September 26, 2025 at 11:38 AM
We have a potential MRC iCASE PhD with AstraZeneca using mass spectrometric techniques to identify the destination organs of endogenous and exogenous peptide hormones. This should be a really interesting PhD, using both ours and AstraZeneca's expertise and mass spectrometry instrumentation.
Reposted
Where do injected peptide weight loss drugs end up in the body? What about known and currently uncharacterised peptides produced in the gut - where do they go? Want to help myself and Andreas Dannhorn from AstraZeneca try and find out how to do this?
September 26, 2025 at 11:38 AM
Where do injected peptide weight loss drugs end up in the body? What about known and currently uncharacterised peptides produced in the gut - where do they go? Want to help myself and Andreas Dannhorn from AstraZeneca try and find out how to do this?
Reposted
blogbirder.blogspot.com/2025/09/bird... The daily birding summary has just gone up on Blogbirder, for those interested in my birding efforts here on Hällögern, a tiny little island in Northern Sweden. I am posting such updates every evening for the next ten days...
Birding at Hällögern; Northern Sweden; 25th September 2025
Adult White-tailed Eagle floating past my position this morning in glorious early morning light. This alone was worth the price of admission...
blogbirder.blogspot.com
September 25, 2025 at 4:13 PM
blogbirder.blogspot.com/2025/09/bird... The daily birding summary has just gone up on Blogbirder, for those interested in my birding efforts here on Hällögern, a tiny little island in Northern Sweden. I am posting such updates every evening for the next ten days...
Reposted
Highlighting some of the many current pitfalls of A.I. in health care
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
If A.I. Can Diagnose Patients, What Are Doctors For?
Large language models are transforming medicine—but the technology comes with side effects.
www.newyorker.com
September 22, 2025 at 2:34 PM
Highlighting some of the many current pitfalls of A.I. in health care
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
@newyorker.com
@dhruvkhullar.bsky.social
www.newyorker.com/magazine/202...
Reposted
Happy International Microorganism Day #internationalmicroorganismday
September 18, 2025 at 5:00 PM
Happy International Microorganism Day #internationalmicroorganismday
Reposted
Nine of the CDC directors over the past 48 years have a lot to say about what RFK Jr is doing vs health of Americans
www.nytimes.com/2025/09/01/o...
www.nytimes.com/2025/09/01/o...
Opinion | We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health
www.nytimes.com
September 1, 2025 at 2:42 PM
Nine of the CDC directors over the past 48 years have a lot to say about what RFK Jr is doing vs health of Americans
www.nytimes.com/2025/09/01/o...
www.nytimes.com/2025/09/01/o...
Reposted
... a night worth sharing maybe? Like xeno-canto.org/584201 ?
XC584201 Soundscape
Crazy night at Ouessant's lighthouse in stormy conditions. Over 15 000 calls featuring at least 27 species. Many birds were circling around the lighthouse to find their way through the mist.
xeno-canto.org
August 23, 2025 at 12:56 PM
... a night worth sharing maybe? Like xeno-canto.org/584201 ?
Reposted
A patient page for GLP-1 drugs and importance of integration of lifestyle factors with these meds
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
July 14, 2025 at 3:24 PM
A patient page for GLP-1 drugs and importance of integration of lifestyle factors with these meds
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted
If you have ever wondered what might happen to short chain fatty acids made by the microbiome. Here is a large class of metabolites and how they link to biology. www.cell.com/cell/fulltex...
The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids
Mass spectrometry data mining tools enabled the creation of an MS/MS spectral library
containing hundreds of N-acyl lipids, including conjugates with short-chain fatty
acids. This resource enabled the...
www.cell.com
June 12, 2025 at 5:56 PM
If you have ever wondered what might happen to short chain fatty acids made by the microbiome. Here is a large class of metabolites and how they link to biology. www.cell.com/cell/fulltex...
Reposted
This is such an incredible paper. Must read if you care about metabolites and cores organ interactions. For me most interesting finding is that the liver is NOT the only organ that converts cholesterol to bile acids. But ther are so many cool onserbwtions www.cell.com/cell/abstrac...
Cross-organ metabolite production and consumption in healthy and atherogenic conditions
An atlas mapping organ-specific metabolite production and consumption across various
pathophysiological states in pigs shows impaired metabolic activity across organs
by a Western diet or hypercholest...
www.cell.com
June 12, 2025 at 3:41 AM
This is such an incredible paper. Must read if you care about metabolites and cores organ interactions. For me most interesting finding is that the liver is NOT the only organ that converts cholesterol to bile acids. But ther are so many cool onserbwtions www.cell.com/cell/abstrac...
Reposted
I’ve seen a few variations of this making the rounds. I like this one best.
I don’t know who the original artist is but thank you to them.
I don’t know who the original artist is but thank you to them.
June 11, 2025 at 10:34 AM
I’ve seen a few variations of this making the rounds. I like this one best.
I don’t know who the original artist is but thank you to them.
I don’t know who the original artist is but thank you to them.
Reposted
Anyone interested in using mass spectrometry to identify and quantify peptides and proteins in plasma, tissue and organoid cell systems?
I have a Research Assistant position in my lab at the Institute of Metabolic Science - Metabolic Research Laboratories.
Apply here:
lnkd.in/dCxhS3GN
I have a Research Assistant position in my lab at the Institute of Metabolic Science - Metabolic Research Laboratories.
Apply here:
lnkd.in/dCxhS3GN
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
June 11, 2025 at 3:11 PM
Anyone interested in using mass spectrometry to identify and quantify peptides and proteins in plasma, tissue and organoid cell systems?
I have a Research Assistant position in my lab at the Institute of Metabolic Science - Metabolic Research Laboratories.
Apply here:
lnkd.in/dCxhS3GN
I have a Research Assistant position in my lab at the Institute of Metabolic Science - Metabolic Research Laboratories.
Apply here:
lnkd.in/dCxhS3GN
Reposted
![[Person with ponytail wearing lab coat hands balloon to another person in front of a springboard, a magnet hanging from above, and then a target] PERSON WITH PONYTAIL to Person 2: Rub this balloon against your head, then go jump past that magnet toward the target on the wall. [caption] Before the bathroom scale was invented, the only way to weigh people was mass spectrometry.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreid7lnvd7afmasx3nxi6anxmyhbatpaw54za3kiw3eaoclrf722faq@jpeg)
Reposted
People rate AI-generated medical answers as more trustworthy & complete—even when wrong. Low-accuracy LLM outputs were seen as valid and actionable, often indistinguishable from doctors’ advice. Unchecked trust in fluent hallucinations poses serious risks.
NEJM AI: ai.nejm.org/doi/full/10....
NEJM AI: ai.nejm.org/doi/full/10....
People Overtrust AI-Generated Medical Advice despite Low Accuracy
This article presents a comprehensive analysis of how artificial intelligence (AI)–generated
medical responses are perceived and evaluated by nonexperts. We conducted a study
in which a total of 30...
ai.nejm.org
May 15, 2025 at 2:07 AM
People rate AI-generated medical answers as more trustworthy & complete—even when wrong. Low-accuracy LLM outputs were seen as valid and actionable, often indistinguishable from doctors’ advice. Unchecked trust in fluent hallucinations poses serious risks.
NEJM AI: ai.nejm.org/doi/full/10....
NEJM AI: ai.nejm.org/doi/full/10....
Reposted
If there any #Sciex decision makers here on Bluesky - I urge you to reconsider. Skyline/Proteowizard support is not only important for your customers using these tools, but it also benefits other bioinformatics efforts that depend on these tools.
Disappointing to see, across both parties.
Sciex is no longer providing funding for Skyline/Proteowizard as part of the multi-vendor agreement to keep Skyline supported across all major vendors.
I can see the arguments from both sides, just a shame it's resulted in this.
Sciex is no longer providing funding for Skyline/Proteowizard as part of the multi-vendor agreement to keep Skyline supported across all major vendors.
I can see the arguments from both sides, just a shame it's resulted in this.
May 15, 2025 at 1:24 AM
If there any #Sciex decision makers here on Bluesky - I urge you to reconsider. Skyline/Proteowizard support is not only important for your customers using these tools, but it also benefits other bioinformatics efforts that depend on these tools.