Mathew Piasecki
mpneurophys.bsky.social
Mathew Piasecki
@mpneurophys.bsky.social
Neuromuscular physiology of ageing and disease.
Associate Professor, School of Medicine, University of Nottingham.
Reposted by Mathew Piasecki
New 3-year PostDoc opportunity in CoMAP, funded by UKRI-BBSRC — developing innovative methods to study motor unit adaptation to ageing and its functional consequences in humans. Please pass on to any who may be interested.

@ukri.org
jobs.nottingham.ac.uk/Vacancy.aspx...
October 22, 2025 at 12:09 PM
Reposted by Mathew Piasecki
Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28...

@jphysiol.bsky.social
NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training-induced changes in muscle morphology, function and gene networks relative to placebo ingestion...
doi.org
October 27, 2025 at 2:10 PM
Reposted by Mathew Piasecki
**Come work with us!!**

Three-year post-doc position funded by Parkinson's UK available Cardiff University - using TMS to study inhibition of planned stepping movements and better understand freezing of gait. Full details here - krb-sjobs.brassring.com/TGnewUI/Sear...

Please share!!
Research Associate: Neural Control of Movement in - Cardiff University - Job Details
Job Details: Research Associate: Neural control of movement in Parkinson's Disease School of Healthcare Sciences, Card
krb-sjobs.brassring.com
October 31, 2025 at 8:55 AM
Reposted by Mathew Piasecki
Please RT
2 new positions in the lab as postdoc & PhD!

Interested in stress, pain, or reward? This project has it all!

We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶

www.jobbnorge.no/en/available...
Postdoctoral Research Fellowship (286516) | University of Oslo
Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
www.jobbnorge.no
September 24, 2025 at 12:22 PM
New 3-year PostDoc opportunity in CoMAP, funded by UKRI-BBSRC — developing innovative methods to study motor unit adaptation to ageing and its functional consequences in humans. Please pass on to any who may be interested.

@ukri.org
jobs.nottingham.ac.uk/Vacancy.aspx...
October 22, 2025 at 12:09 PM
Reposted by Mathew Piasecki
New paper - Sex differences in healthy brain aging are unlikely to explain higher Alzheimer’s Disease prevalence in women: https://doi.org/10.1073/pnas.2510486122
October 14, 2025 at 9:00 AM
Reposted by Mathew Piasecki
🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important

Good collab with @droch.bsky.social so travel to CPH involved as well

www.kcl.ac.uk/jobs/126245-...
Postdoctoral Research Associate in Muscle Biology and Genomics | King's College London
www.kcl.ac.uk
September 25, 2025 at 5:01 PM
We had a little appearance on Channel4 last night; Michael Mosley: Secrets of the Superagers

Michael came to our lab and tried a few of our methods, including needle EMG

See 36 mins in for some pretty good spikes 😎

www.channel4.com/programmes/m...
July 22, 2025 at 7:34 PM
Reposted by Mathew Piasecki
Mathew Piasecki of uniofnottingham.bsky.social discusses motor unit adaptation to disuse: crossing the threshold from firing rate suppression to #neuromuscular junction transmission ⚙️ 🔎

📖 Read the #TopicalReview here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
July 16, 2025 at 1:04 PM
Reposted by Mathew Piasecki
Penultimate presentation from our group at @northumbriauni.bsky.social is @elisanedelec.bsky.social presenting her work on knee extensior neuromuscular function across the menstrual cycle at @ecssofficial.bsky.social in Rimini, Italy 🇮🇹
July 4, 2025 at 11:43 AM
Reposted by Mathew Piasecki
Second up from our group from @northumbriauni.bsky.social is @padraig-spillane.bsky.social presenting his work titled Contraction intensity-specific fluctuations in motor unit behaviour across the menstrual cycle at @ecssofficial.bsky.social in Rimini, Italy 🇮🇹
July 2, 2025 at 6:24 AM
Reposted by Mathew Piasecki
francoishug.bsky.social‬ et al. investigated non-homogeneous distribution of inhibitory inputs amon#motoror units in response t#nociceptiveve stimulation at moderate contraction intensity ⚙️ ✍️

📜 Read th#Researchch here: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP288504
June 12, 2025 at 2:11 PM
Reposted by Mathew Piasecki
Chronic resistance and endurance training alters the way in which motor unit discharge rates are modulated across contraction intensities, suggesting alterations in net excitatory synaptic input - another fun collaboration with @jskarabot.bsky.social and colleagues.

www.biorxiv.org/content/10.1...
June 6, 2025 at 9:29 PM
Reposted by Mathew Piasecki
🆕📝 New publication in @jphysiol.bsky.social “Non-homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity”
🔗 doi.org/10.1113/JP28...
@univcotedazur.bsky.social @simonavrillon.bsky.social @agencerecherche.bsky.social
Non‐homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity
Abstract figure legend We combined experimental data and in silico models to investigate the contribution of inhibitory and neuromodulatory inputs to motor unit behaviour in response to nociceptive s....
doi.org
June 1, 2025 at 6:30 AM
Reposted by Mathew Piasecki
Senior Editors Paul. L. Greenhaff & Harold D. Schultz examine the central role of human and clinical physiology in the era of multi-omics and inter-organ crosstalk ✍️

🔗 Read the #Editorial here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
May 13, 2025 at 11:03 AM
Reposted by Mathew Piasecki
‘Load and muscle-dependent changes in triceps surae motor unit firing properties in individuals with non-insertional Achilles tendinopathy’ Our latest study has just been published in @jphysiol.bsky.social - open access below
Load and muscle‐dependent changes in triceps surae motor unit firing properties in individuals with non‐insertional Achilles tendinopathy
Abstract figure legend Motor unit firing properties of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SO) muscles were assessed using high-density surface electromyography (HD....
physoc.onlinelibrary.wiley.com
May 11, 2025 at 11:13 PM
Reposted by Mathew Piasecki
The revival of an old metaphor, first coined by Henri Bergson in the 1880s - the brain is (or has) a switchboard!
A subcortical switchboard for perseverative, exploratory and disengaged states - Nature
Behavioural experiments in mice demonstrate that GABAergic (γ-aminobutyric acid-expressing), glutamatergic and serotonergic neurons in the median raphe nucleus have distinct and complementary function...
www.nature.com
April 30, 2025 at 3:24 PM
Reposted by Mathew Piasecki
Tomomichi Oya of @westernuwin.bsky.social writes this #Perspective on Dernoncourt et al. (2025), as their experimental results raise several important considerations regarding MU #flexibility 💭

🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
April 29, 2025 at 11:02 AM
Reposted by Mathew Piasecki
Job Alert (please repost)!

We are looking to hire a Research Assistant to join us in an exciting project looking into Brain-Computer Interfaces (BCIs) and how brains learn to control them.
April 14, 2025 at 11:04 AM
Reposted by Mathew Piasecki
📣 CALL FOR PAPERS 📣

Organised by @pgreenhaff.bsky.social & focusing on:

🚑 Injury and rehabilitation
⛰️ Altitude physiology
🦵 Muscle adaptation
🚴 Exercise training
💉 Pharmacological interventions
⚙️ Body composition

🔗 buff.ly/2sVbnLk
April 8, 2025 at 3:02 PM
Reposted by Mathew Piasecki
My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. A BBSRC-funded project in collaboration with Matt Apps (Birmingham) & Nathan Lepora (Bristol)

Closes May 5th

Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...
Job Vacancy at the University of Nottingham: Research Assistant (Fixed Term)
We seek a predoctoral research assistant to join the Humphries’ group at the University of Nottingham on a BBSRC-funded project to study the neural basis of foraging, in collaboration with the groups ...
jobs.nottingham.ac.uk
April 8, 2025 at 9:18 AM
Reposted by Mathew Piasecki
Clinical and humans physiology to the fore. Think about submitting your work to The Journal of Physiology.

doi.org/10.1113/jp28...
Here comes the sun: the central role of human and clinical physiology in the era of multi‐omics and inter‐organ crosstalk
Click on the article title to read more.
doi.org
March 31, 2025 at 9:22 AM
Reposted by Mathew Piasecki
New pub from Drew in CJ’s lab. We showed prolonged firing of motoneurons makes it hard to control force, estimates of PICs are larger at short muscle lengths, and combining the two exacerbates this prolongation of firing-induced force variability.

physoc.onlinelibrary.wiley.com/doi/full/10....
Intrinsic properties of spinal motoneurons degrade ankle torque control in humans
Abstract figure legend All motor commands are processed via spinal motoneurons, whose intrinsic electrical properties are adapted by brainstem neuromodulatory inputs. The effects of these neuromodula....
physoc.onlinelibrary.wiley.com
March 30, 2025 at 4:12 PM
Reposted by Mathew Piasecki
Reposted by Mathew Piasecki
…been silent for a while, reappeared with a piece in @jphysiol.bsky.social on #MotorControl #Neurophysiology and #AI #history -> behavioral research holds valuable insights that new AI methods can leverage to understand brain function.
tinyurl.com/cbc64ff6
#neuroscience #NeuroAI #cognitivescience
À la recherche du temps perdu: will AI and 150 years of human movement research drive the next Neuroscience revolution?
Click on the article title to read more.
tinyurl.com
March 18, 2025 at 7:51 AM