The Journal of Physiology
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jphysiol.bsky.social
The Journal of Physiology
@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
🔬 Call for Papers: Channelopathies in Focus

Focusing on #ionchannel–related diseases, from classical plasma‑membrane #channelopathies to emerging roles of organellar channels, non‑excitable cell physiology, and channel‑dependent #signalling.

📍 🔗 physoc.onlinelibrary.wiley.com/hub/journal/...
February 12, 2026 at 4:01 PM
Praveen Kuruppath and colleagues from @cuanschutz-dpb.bsky.social observed that connexin 36-mediated gap junctions contribute to fine odour discrimination and late-phase excitation of #mitral cells in the mouse #olfactory bulb 🧠 🐁

🔗 Read the study: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 12, 2026 at 2:02 PM
Mingyue Yin, Boyi Zhang, Kai Xu & Jia Wei offer this #JournalClub "Does intensity matter? Insight from divergent #adipose tissue molecular responses following #exercise" based on the study by Ahn et al. (2025) ✍️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 12, 2026 at 12:02 PM
Dilek Ocal, Brian L. Day, Amy Peters, Matt Bancroft, David Cash, Diego Kaski, Natalie S. Ryan, Sebastian J. Crutch, Keir X. X. Yong find that #visual modulation of vestibular-evoked balance response is disturbed by posterior #cortical atrophy 👁️ 🧠

📜 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 11, 2026 at 4:19 PM
In this recent study, Carol T. Bussey and colleagues investigated anti-#arrhythmic targeting of sympathetic stellate ganglion #P2X3 receptors 🫀 🔬

Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 11, 2026 at 2:03 PM
Reposted by The Journal of Physiology
6 wks unilateral interval training w/ blood-flow restriction (BFR) ↑ peak power (~17% vs control), ↓ neuromuscular fatigue (MVC/QT), ↑ femoral blood flow (RH/ROV) and ↓ HR/MAP during metaboreflex exercise. Published in @jphysiol.bsky.social

physoc.onlinelibrary.wiley.com/doi/10.1113/...
Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations
Abstract figure legend We investigated how 6 weeks of dynamic knee-extensor interval training with blood flow restriction (BFR-leg) and without (CTRL-leg) impacts performance and its mechanisms using...
physoc.onlinelibrary.wiley.com
February 10, 2026 at 5:02 PM
Martin Zaback, Mohamed H. Mousa from @temple.edu & Robyn L. Mildren present this #JournalClub "Shining light on #spinal co-ordination: internal states shape #interneuron recruitment of muscle synergies" based on the work of He et al. (2025) ✍️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 11, 2026 at 12:02 PM
🚀 If you’re within 10 years of your PhD and passionate about advancing physiology, we want to hear from you!

Apply for our Editorial Board Fellowship for your chance to work with Senior Editors and gain real insight into the publishing process.🎓️

🔗✍️
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February 10, 2026 at 3:04 PM
Chloe Cable, Sidney P. Kuo and Eric A. Newman observed that junctional conductance of #retinal AII amacrine cell electrical synapses is decreased by #NMDA receptors 👁️ 🧠

📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 10, 2026 at 1:01 PM
Richard A. Greendyk, Glauco M. Plens & Ewan C. Goligher from @utoronto.ca present this #TranslationalPerspective "How we deliver energy to the lung matters: Mechanistic clues for safer ventilation" based on the work of Cominesi et al. (2025) 🫁 💭

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 10, 2026 at 12:01 PM
Giuseppe T. Patané, Ruben J. Moreira, Annamaria Russo, Maria L. Pereira, Pedro F. Oliveira, Davide Barreca & Marco G. Alves examine #lifestyle implications of the paradox and management of oxidative #stress in sperm 🔬 🍽️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 9, 2026 at 3:02 PM
📢 Call for Papers

The Physiology of Obesity: From Mechanisms to Medicine🔬

🗓️⏰️ Deadline extended: 6th April 2026

We’re seeking cutting‑edge research exploring the biology of #obesity, from #metabolic mechanisms to #clinical innovation.

📌 🔗 physoc.onlinelibrary.wiley.com/hub/journal/...
February 9, 2026 at 2:46 PM
This recent study by Toshimi Yamanaka and Yutaka Hirata investigates cross-modal predictive #oculomotor control, indicating that visually acquired prediction transfers to vestibular-driven eye movements 👁️ ⏰️

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 9, 2026 at 2:02 PM
In their recent letter to the editor, Adrian Bayonas-Ruiz and Barbara Bonacasa from @um.es discuss ways of rethinking #oxygen handling in exercising muscle, from #myoglobin deficiency to a CO shield, and the work of Zoladz et al. (2024) ✍️ ✉️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 9, 2026 at 12:02 PM
Luke A. Henderson from @sydney.edu.au examines the recent work of Ocal et al. (2025) in this #Perspective, 'Balance in the face of altered visual circuitry anatomy' ✍️ 💭

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 8, 2026 at 4:00 PM
'When the brain listens to the kidney, is it TRP'n or what?'

John W. Osborn, Louise C. Evans, Christopher T. Banek, Lucy Vulchanova & Alex Dayton offer this #Perspective on the work of Sullivan et al. (2025) ✍️ 💭

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 8, 2026 at 2:02 PM
Jacob B. Sullivan, Leon J. DeLalio & Sean D. Stocker observed that deletion of the #TRPV1 channel attenuates afferent #renal nerve responses to renal artery occlusion but not elevated renal pelvic pressure 🔬 ⚡️

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 7, 2026 at 4:02 PM
Nazih L. Nakhoul discusses gas channels and CO2 transport across cell membranes and the recent work of Wang et al. (2025) ✍️

🔗 Read their #Perspective: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 7, 2026 at 12:00 PM
#Research by Alyssa R. Kniffin, Erin A. English & Lisa A. Briand from @temple.edu concludes that PKMζ is necessary for long-term depression and long-term #potentiation in the medial #prefrontal cortex 🧠 ⏰️

📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 6, 2026 at 4:01 PM
🎓️ EDITOR'S CHOICE 🎓️

Chou et al. show that cough depends on the proton content of #gastric contents and is mediated by acid-sensing ion channels on vagal afferents. This work has relevance for the prevention of aspiration #pneumonia 🫁

📜 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 6, 2026 at 2:02 PM
In this letter to the editor, Faming Wang suggests that redefining human #heat limits requires accurate quantification of core temperature #threshold in response to a recent opinion article by Bouchama (2025) ✉️ ✍️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 6, 2026 at 12:10 PM
#Research by Deng-Ke Wang, Fraser J. Moss & Walter F. Boron examined the synergistic roles of aquaporin 5 and intra- and extracellular carbonic anhydrases in promoting #CO2 diffusion across the Xenopus oocyte #plasmamembrane 🔬

📜 Read the study: physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 5, 2026 at 4:03 PM
🎓 APPLY NOW 🎓

Are you an ECR seeking some Editorial Board experience?

Our #EditorialBoardFellowship is a great opportunity to be directly involved in the editorial process under the guidance of a Senior Editor!

⏰ Applications close 15th March⤵️
physoc.onlinelibrary.wiley.com/hub/journal/...
February 5, 2026 at 1:02 PM
Xinyu Liu, Meihan Guo, David Montero offer this #Opinion article refuting the ‘high blood volume–high blood pressure’ rationale in women and men 💭 ✍️

🔗 👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
February 5, 2026 at 12:02 PM
LATEST ISSUE NOW LIVE 🎉

The cover depicts findings from Dilek Ocal and colleagues' investigation into the vestibular control of uprightness during stance using GVS under various proprioceptive and visual conditions. 🧠 📸

🔗 📖 physoc.onlinelibrary.wiley.com/toc/14697793...
February 5, 2026 at 10:51 AM