The Journal of Physiology
@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
In this recent #Technique article, Matthew D. Lee et al. outline the use of #VasoTracker2 as an open-source software and hardware for tracking blood vessel diameter and assessing #vascular function 💻 🫀
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 13, 2025 at 5:00 PM
In this recent #Technique article, Matthew D. Lee et al. outline the use of #VasoTracker2 as an open-source software and hardware for tracking blood vessel diameter and assessing #vascular function 💻 🫀
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Alexis Ruiz of unibas.ch et al. finds that massive reduction of RyR1 in #muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes #scoliosis 🔬 🔎
📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 13, 2025 at 2:02 PM
#Research by Alexis Ruiz of unibas.ch et al. finds that massive reduction of RyR1 in #muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes #scoliosis 🔬 🔎
📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this study, David C. Andrade et al. observed that the #carotid body mediates peak #oxygen uptake during maximal physical exertion in rats 🫀 🏃
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 13, 2025 at 12:01 PM
In this study, David C. Andrade et al. observed that the #carotid body mediates peak #oxygen uptake during maximal physical exertion in rats 🫀 🏃
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Rémi Montané of toulouseuniversite.bsky.social et al. observes that brown #adipose tissue activity impacts systemic #lactate clearance in male mice 🔬 📉
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 12, 2025 at 2:00 PM
#Research by Rémi Montané of toulouseuniversite.bsky.social et al. observes that brown #adipose tissue activity impacts systemic #lactate clearance in male mice 🔬 📉
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this study, Ysabella I. Ruiz-Pick et al. observed that KV channel antagonism blunts #vasodilatation in skeletal muscle of humans 🔎 🔬
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 12, 2025 at 12:01 PM
In this study, Ysabella I. Ruiz-Pick et al. observed that KV channel antagonism blunts #vasodilatation in skeletal muscle of humans 🔎 🔬
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Jodie L. Koep et al. investigates preferential lactate #metabolism in the human brain during exogenous and endogenous #hyperlactataemia 🧠 🚴
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 11, 2025 at 12:01 PM
#Research by Jodie L. Koep et al. investigates preferential lactate #metabolism in the human brain during exogenous and endogenous #hyperlactataemia 🧠 🚴
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this #TopicalReview, Michael G. Jonz of uottawa.ca examines adaptations to #hypoxia in the vertebrate #retina 👁️ 🧠
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 10, 2025 at 2:02 PM
In this #TopicalReview, Michael G. Jonz of uottawa.ca examines adaptations to #hypoxia in the vertebrate #retina 👁️ 🧠
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Christoph T. Block et al. investigated saltatory #axonal conduction in the avian #retina 👁️ 🐦
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 10, 2025 at 12:02 PM
#Research by Christoph T. Block et al. investigated saltatory #axonal conduction in the avian #retina 👁️ 🐦
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Rikard Frederiksen et al. examine the #evolution of rod bipolar cells and rod #vision in this #TopicalReview 🔬 👁️
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 7, 2025 at 3:03 PM
Rikard Frederiksen et al. examine the #evolution of rod bipolar cells and rod #vision in this #TopicalReview 🔬 👁️
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Recent #Research by Espen Hartveit examined subcellular localization, kinetic properties and functional dynamics of #HCN channels in rod bipolar cells of rat #retina 🔎 👁️
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 7, 2025 at 12:02 PM
Recent #Research by Espen Hartveit examined subcellular localization, kinetic properties and functional dynamics of #HCN channels in rod bipolar cells of rat #retina 🔎 👁️
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this #TopicalReview, Victor Calbiague-Garcia of sorbonne-universite.fr et al. review current knowledge of #amacrine cells & discuss how emerging approaches are advancing our understanding of their function 👁️ 🐁
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 6, 2025 at 3:03 PM
In this #TopicalReview, Victor Calbiague-Garcia of sorbonne-universite.fr et al. review current knowledge of #amacrine cells & discuss how emerging approaches are advancing our understanding of their function 👁️ 🐁
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this study, Thomas E. Zapadka et al. observed that #optic nerve injury impairs intrinsic mechanisms underlying electrical activity in a resilient #retinal ganglion cell 👁️ 🔬
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 6, 2025 at 12:00 PM
In this study, Thomas E. Zapadka et al. observed that #optic nerve injury impairs intrinsic mechanisms underlying electrical activity in a resilient #retinal ganglion cell 👁️ 🔬
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this opening #Editorial, Jonathan B. Demb, Karin Dedek & Wei Li introduce the latest special issue 'Cellular and synaptic mechanisms of retinal processing' 📖
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 5, 2025 at 4:01 PM
In this opening #Editorial, Jonathan B. Demb, Karin Dedek & Wei Li introduce the latest special issue 'Cellular and synaptic mechanisms of retinal processing' 📖
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Tian Kong & Lu-Yang Wang offer this #Perspective on dynamic inter-conversion between dendritic filopodia and spines based on the work of Liu et al. (2025) ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 5, 2025 at 3:05 PM
Tian Kong & Lu-Yang Wang offer this #Perspective on dynamic inter-conversion between dendritic filopodia and spines based on the work of Liu et al. (2025) ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Kristen M. Harris examines enhanced cycling of #presynaptic vesicles during long-term potentiation in rat #hippocampus in this recent #TopicalReview 📖 🔬
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 5, 2025 at 12:03 PM
Kristen M. Harris examines enhanced cycling of #presynaptic vesicles during long-term potentiation in rat #hippocampus in this recent #TopicalReview 📖 🔬
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
📣 Call for papers!!! 📣
Special Issue on New Approach Methodologies (NAMs) in Precision Medicine, fully open access with no author publication fees!
Special Issue on New Approach Methodologies (NAMs) in Precision Medicine, fully open access with no author publication fees!
📣 CALL FOR PAPERS📣
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
October 29, 2025 at 4:04 PM
📣 Call for papers!!! 📣
Special Issue on New Approach Methodologies (NAMs) in Precision Medicine, fully open access with no author publication fees!
Special Issue on New Approach Methodologies (NAMs) in Precision Medicine, fully open access with no author publication fees!
Reposted by The Journal of Physiology
Recent #Research by Allison Spillane of uwhealth.bsky.social et al. investigates precision therapeutic #tRNA rescue of nonsense mutation R166X in KCNJ13 to restore K+ channel function 🧬 🔬
📜 Read it here: www.jprecisionmedicine.org/article/S305...
📜 Read it here: www.jprecisionmedicine.org/article/S305...
November 4, 2025 at 4:00 PM
Recent #Research by Allison Spillane of uwhealth.bsky.social et al. investigates precision therapeutic #tRNA rescue of nonsense mutation R166X in KCNJ13 to restore K+ channel function 🧬 🔬
📜 Read it here: www.jprecisionmedicine.org/article/S305...
📜 Read it here: www.jprecisionmedicine.org/article/S305...
In this #TopicalReview, Yimei Cai & Tingting Wang discuss regulation of presynaptic homeostatic plasticity by glial signalling in #Alzheimer's disease 📖 ⚙️
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 4, 2025 at 3:04 PM
In this #TopicalReview, Yimei Cai & Tingting Wang discuss regulation of presynaptic homeostatic plasticity by glial signalling in #Alzheimer's disease 📖 ⚙️
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Sofiia Reshetniak of uni-goettingen.de et al. examine the synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function in this #TopicalReview 📖 🧠
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 4, 2025 at 12:02 PM
Sofiia Reshetniak of uni-goettingen.de et al. examine the synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function in this #TopicalReview 📖 🧠
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🎓 EDITOR'S CHOICE🎓
#Research by Nadine Dyszkant of unituebingen.bsky.social et al. observed that photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types 👁️ 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Nadine Dyszkant of unituebingen.bsky.social et al. observed that photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types 👁️ 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 4, 2025 at 11:01 AM
🎓 EDITOR'S CHOICE🎓
#Research by Nadine Dyszkant of unituebingen.bsky.social et al. observed that photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types 👁️ 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Nadine Dyszkant of unituebingen.bsky.social et al. observed that photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types 👁️ 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28...
@jphysiol.bsky.social
@jphysiol.bsky.social
NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training-induced changes in muscle morphology, function and gene networks relative to placebo ingestion...
doi.org
October 27, 2025 at 2:10 PM
Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28...
@jphysiol.bsky.social
@jphysiol.bsky.social
In this #TopicalReview, Cristian A. Bogaciu & Silvio O. Rizzoli of uni-goettingen.de discuss membrane trafficking of synaptic adhesion molecules ✍️ 🔎
Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 3, 2025 at 3:03 PM
In this #TopicalReview, Cristian A. Bogaciu & Silvio O. Rizzoli of uni-goettingen.de discuss membrane trafficking of synaptic adhesion molecules ✍️ 🔎
Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Zsuzsanna Fekete et al. investigated #synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse #prefrontal cortex ⚙️ 🧠
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 3, 2025 at 12:01 PM
#Research by Zsuzsanna Fekete et al. investigated #synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse #prefrontal cortex ⚙️ 🧠
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
LATEST ISSUE LIVE⬇️
'Cellular and synaptic mechanisms of retinal processing' 👁️🧠
🔗 physoc.onlinelibrary.wiley.com/toc/14697793...
'Cellular and synaptic mechanisms of retinal processing' 👁️🧠
🔗 physoc.onlinelibrary.wiley.com/toc/14697793...
November 3, 2025 at 11:01 AM
LATEST ISSUE LIVE⬇️
'Cellular and synaptic mechanisms of retinal processing' 👁️🧠
🔗 physoc.onlinelibrary.wiley.com/toc/14697793...
'Cellular and synaptic mechanisms of retinal processing' 👁️🧠
🔗 physoc.onlinelibrary.wiley.com/toc/14697793...
Jeremy S. Dittman offers this #Perspective on the work of Lin et al. into vesicle priming states and the math of plasticity ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 1, 2025 at 6:01 PM
Jeremy S. Dittman offers this #Perspective on the work of Lin et al. into vesicle priming states and the math of plasticity ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...