Mady Hornig, MA, MD
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mhornig.bsky.social
Mady Hornig, MA, MD
@mhornig.bsky.social
1.3K followers 1.4K following 43 posts
Translational MD-scientist, mom, 🎶 | Bklyn born + bred

Pathogen/microbe-host interactions + 🧠outcomes across the life course | gut-immune-🧠 axis

#ASD #ADHD #PANS/#PANDAS #OCD affective disorders/#TRD Alzheimer’s #MECFS #LongCOVID

All posts = my views
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Reposted by Mady Hornig, MA, MD
physiciandemocracy.medsky.social
www.nyc.gov/site/doh/cov...
#medsky
The only way to prevent long COVID is to avoid getting COVID19. With every infection, there is a risk of developing long COVID.
October 3, 2025 at 10:56 AM
Reposted by Mady Hornig, MA, MD
atranscendedman.bsky.social
Long COVID (and life) teaches you this.

Research imagines what medicine could be, but medicine often shrugs.

The best doctors chase the questions.

The worst don’t even look up.
September 26, 2025 at 6:56 PM
mhornig.bsky.social
bsky.app/profile/mhor...
mhornig.bsky.social Mady Hornig, MA, MD @mhornig.bsky.social · Sep 26
Important new work from @leorahorwitzmd.bsky.social + NIH RECOVER (incl my son Max 🥰). Link👇

Nearly 80% of those with self-reported change in/loss of sense of smell after SARS-CoV-2 infection were found to have ↓ olfactory function on formal testing. Rate ↑ but not entirely unexpected.
September 26, 2025 at 8:22 PM
mhornig.bsky.social
Important new work from @leorahorwitzmd.bsky.social + NIH RECOVER (incl my son Max 🥰). Link👇

Nearly 80% of those with self-reported change in/loss of sense of smell after SARS-CoV-2 infection were found to have ↓ olfactory function on formal testing. Rate ↑ but not entirely unexpected.
September 26, 2025 at 8:09 PM
Reposted by Mady Hornig, MA, MD
tomkindlon.bsky.social
The NIH in the US have highlighted a recent ME/CFS study they funded:

"Overactive immune responses in ME/CFS"

www.nih.gov/news-events/...

#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @mhornig.bsky.social
NIH logo Home News & Events NIH Research Matters September 23, 2025 Overactive immune responses in ME/CFS At a Glance Researchers found signs of overactive immune responses in people with myalgic encephalomyelitis/chronic fatigue syndrome, or ME/CFS. The findings provide insights into the causes of ME/CFS and suggest new treatment approaches. ME/CFS involves unexplained fatigue that may worsen after exertion and cause problems with thinking and memory that lasts at least six months. People with ME/CFS often report symptoms consistent with infection before developing ME/CFS. Yet no single microbe has been found to be responsible. This suggests that ME/CFS may be caused by a more general immune response to infection. To test this idea, a research team from several institutions, led by Dr. W. Ian Lipkin at Columbia University Mailman School of Public Health, collected blood samples from
September 24, 2025 at 12:29 PM
mhornig.bsky.social
Great to speak w/@jasongale.bsky.social to add much-needed depth back into the still-unfolding story of autism pathogenesis. Hopefully helps to course-correct Monday's WH presser, which put forth clinical guidance many find worrisome + dangerous for pregnant women + their developing offspring.
September 23, 2025 at 6:37 AM
Reposted by Mady Hornig, MA, MD
drinfosec.bsky.social
🚨🧵 by @david.notesforfriends.com about Covid's damage & a cigarette metaphor:

"Your Body Is Keeping Score
Here’s the thing nobody gets: COVID doesn’t give a shit about your positive thinking. It’s not checking your Instagram to see..."

Full🎯thread here:
threadreaderapp.com/thread/19645...
COVID Isn’t a Cold. It’s Cigarettes All Over Again The Damage Is Everywhere – That Is the Definition of Long COVID Look, we’ve been here before. My grandpa smoked two packs a day for most of my memory of him. Everyone did. Doctors literally prescribed cigarettes for stress. They said it was good for you. Made you look cool. Helped you lose weight. Whatever. He felt fine until he didn’t. That’s exactly what’s happening with COVID right now, and nobody wants to hear it. People are catching this thing two, three times a year and acting like it’s nothing. Just a cold. Just the sniffles. Meanwhile, their blood vessels are getting shredded. Their organs are taking hits. Their brains are leaking.... More at the link in the main post
September 7, 2025 at 3:45 PM
mhornig.bsky.social
Not just scientists and universities anymore: threat to nonprofits: insurance companies are cancelling insurance because of environmental advocacy

eedition.timesunion.com/infinity/art...
Audubon chapter gets surprise insurance cancellation
Audubon chapter gets surprise insurance cancellation
eedition.timesunion.com
May 5, 2025 at 8:54 PM
Reposted by Mady Hornig, MA, MD
georgetakei.bsky.social
When the moment came, Harvard didn’t hedge or flinch—it stood up. A reminder that integrity isn’t complicated, it’s just rare.
April 24, 2025 at 8:51 PM
mhornig.bsky.social
Jesse Welles delivers one more time what you’ve probably been trying to put into words…

RED
#singersongwriter #country #folk #song
👇👇👇
April 14, 2025 at 5:11 PM
mhornig.bsky.social
"Driving under viral impairment"

▶︎ #SARSCoV2 PCR positivity rates (CDC) associated w/car crashes: OR 1.25 [1.23-1.26]

▶︎ independent of Long COVID status/vaccination status

▶︎ risk analogous to driving impairment w/EtOH at legal limits

dx.plos.org/10.1371/jour...
Driving under viral impairment: Linking acute SARS-CoV-2 infections to elevated car crash risks
This study explores the linkage between acute SARS-CoV-2 and car crashes across U.S. states, correlating with COVID-19 mitigation strategies, vaccination rates, and Long COVID prevalence. This investi...
dx.plos.org
April 10, 2025 at 6:59 PM
mhornig.bsky.social
h/t Collab for Health & Environment @che-healthenv.bsky.social

Lawyers for Good Government is providing legal advice/support for all qualifying federal grantees w/funding at risk.

1:1 consultations pro bono to EPA, USDA, DOE grantees.

See: www.lawyersforgoodgovernment.org/fund-protect...
Fund Protection Legal Guidance Request — Lawyers for Good Government
www.lawyersforgoodgovernment.org
March 29, 2025 at 4:05 PM
Reposted by Mady Hornig, MA, MD
carlbergstrom.com
1. Today in Santa Barbara I saw an extraordinary abstract art piece—or so it seemed—from Hank Willis Thomas.

As we speak, Trump seeks to erase large swaths of our history, attempting to erase the most shameful parts of our history, and paint over the triumphs and sacrifices of people of color.
Art piece with an American flag, slashes of paint, and large white splotches.
March 17, 2025 at 1:14 AM
mhornig.bsky.social
For context, as we extend past 5 years from the start of the pandemic:

Although some findings in Long COVID are reminiscent of the illness duration effect we found in ME/CFS 👇, immune analyses over time in rigorous prospective, long-term studies of Long COVID are imperative to pursue now.
valebodi.bsky.social valebodi.bsky.social @valebodi.bsky.social · Mar 16
Ten years ago Distinct plasma immune signatures in ME/CFS are present early in the course of illness by @mhornig.bsky.social et al. was published in Science
www.science.org/doi/10.1126/... The researchers showed that #ME/CFS is a temporally non static immune mediated disease
Distinct plasma immune signatures in ME/CFS are present early in the course of illness
Cytokine alterations are more strongly correlated with illness duration than with measures of illness severity.
www.science.org
March 16, 2025 at 5:17 AM
Reposted by Mady Hornig, MA, MD
markigra.sciences.social.ap.brid.gy
DOGE/SSA marked this person dead and *removed his savings from his bank account,* cancelled his social security and Medicare. #seattle https://www.seattletimes.com/seattle-news/politics/heres-a-dead-person-on-social-security-in-seattle-with-plenty-to-say/
The Seattle Times "There's nothing you need to do - we've deducted the funds from LEONARD A. JOHNSON's account." Uh oh. It itemized how $5,201 had been stricken from their bank account, on the grounds that Ned wasn't justified to get those benefits - because he was dead. That was for payments he'd received in December and January. Ned found that his February Social Security check hadn't been paid, and he's yet to receive his March check, either. His Medicare insurance had been canceled. He also learned that when you die, your credit score gets marked as "deceased, do not issue credit," which makes it tough to get a loan.
March 15, 2025 at 2:27 PM
Reposted by Mady Hornig, MA, MD
atrupar.com
Walz: "The idea that the secretary of education would not know what IDEA is -- individuals with disability in education act -- that's like your mechanic not knowing how to put air in your tire. And she's in charge of this nation's education progress. It is catastrophic."
March 13, 2025 at 12:35 AM
Reposted by Mady Hornig, MA, MD
artcandee.bsky.social
AOC:

"It's not just that Trump is corrupt. It's that everyone participating in this is corrupt. Elon is corrupt. Jeff Bezos is corrupt. Mark Zuckerberg is corrupt."

🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥
March 9, 2025 at 6:32 PM
Reposted by Mady Hornig, MA, MD
jerasikehorn.bsky.social
What a wonderful idea…👇

Let’s. Do. This. ✨
March 7, 2025 at 9:25 PM
Reposted by Mady Hornig, MA, MD
ardemp.bskyverified.social
In case you were wondering how Fox News is covering the proposed cuts at the NIH:
February 23, 2025 at 1:45 AM
Reposted by Mady Hornig, MA, MD
plosbiology.org
PLOS has issued a statement on recent US Executive Orders and scientific integrity.

We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.

plos.io/3D4O8cH
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
plos.io
February 21, 2025 at 3:41 PM
Reposted by Mady Hornig, MA, MD
kjohnstone.bsky.social
There's a wonderful letter to Cochrane about their outdated and harmful review of exercise as a treatment for ME/CFS, organised by @davidtuller1 and signed by a group of experts.
virology.ws/2025/02/20/t...
virology.ws
February 21, 2025 at 7:33 AM
mhornig.bsky.social
Great 🧵by
@leorahorwitzmd
on the new JAMA ppr on 2024 update to #NIHRECOVER #LongCOVID index. Also listen to her incisive presentation on the podcast (see🔗👇).

Great to work w/this group as we strive to refine understanding of this disabling disorder's clinical manifestations
December 20, 2024 at 12:43 AM
Reposted by Mady Hornig, MA, MD
bhanlon15.bsky.social
12/18, JAMA: “2024 Update of the RECOVER-Adult Long COVID Research Index”

Linda N. Geng, MD, Kristine M. Erlandson, MD, Mady Hornig, MA, MD et al.

jamanetwork.com/journals/jam...?
2024 Update of the RECOVER-Adult Long COVID Research Index
This prospective, observational cohort study uses data from the Researching COVID to Enhance Recovery adult cohort to assess post–COVID-19 condition (or long COVID) with additional participant data an...
jamanetwork.com
December 18, 2024 at 10:25 PM
mhornig.bsky.social
OK #oncsky: 45+y ago Koprowski proposed CA19-9 as part of #PDAC screening armamentarium. Yet few pubs on clinical f/u of assay discordance.

👇 (*same* hosp sys; no known clin correlate):
Siemens assays consistently ↑↑ (mid-triple digits)
Beckman assays consistently normal

Which assay do you trust?
CA19-9 discordance by immunoassay: Siemens chemiluminometric assay consistently high (mid-triple digits) Beckman DxI consistently normal range (<<<cutoff)
November 26, 2024 at 4:41 PM
Reposted by Mady Hornig, MA, MD
physiciandemocracy.medsky.social
November 24, 2024 at 2:35 AM