Melanie Bonhivers
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mbonhivers.bsky.social
Melanie Bonhivers
@mbonhivers.bsky.social
83 followers 170 following 1 posts
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Reposted by Melanie Bonhivers
fronzeslab.bsky.social
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.

www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
www.science.org
November 21, 2025 at 7:05 PM
Reposted by Melanie Bonhivers
univbordeaux.bsky.social
#Agenda 📆Samedi 22/11, le département Sciences biologiques et médicales (SBM) de l’université de Bordeaux ouvre les portes de ses laboratoires de recherche afin de faire découvrir ses activités scientifiques et techniques :
www.u-bordeaux.fr/ev...
November 19, 2025 at 12:00 PM
Reposted by Melanie Bonhivers
ebertiaux.bsky.social
Honored to receive the FEBS Booster Funds 2025.
My sincere thanks to FEBS for this recognition and their support of early-career researchers.

This funding will greatly help advance my work.
Congratulations as well to all fellow 2025 awardees.
November 18, 2025 at 12:54 PM
Reposted by Melanie Bonhivers
keithrmatthews.bsky.social
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (elxw.fa.em3.oraclecloud.com/hcmUI/Candid...). Find out more about us in the link below.
The Matthews Lab | Biology
The Matthews Lab
biology.ed.ac.uk
October 17, 2025 at 12:06 PM
Reposted by Melanie Bonhivers
veupathdb.org
#FungiDB/#VEuPathDB & #Ensembl are teaming up to improve #fungal & #oomycete genome resources for #phytopathogens — & we want your input! 🧬🍄

🗓️ Complete the survey by Nov 1, 2025:
🔗 zurl.co/gKjC1
Your feedback will guide genome curation, annotation & data integration #genomics #foodsecurity
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zurl.co
October 17, 2025 at 9:13 AM
Reposted by Melanie Bonhivers
plosbiology.org
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
A Trypanosoma brucei cell visualized by confocal microscopy after ultrastructure expansion. The cell was immunolabelled for the BILBO1 protein (yellow) and stained with fluorescent NHS-ester (grey). The flagellar pocket is highlighted in pink. Credit: Marie Zelená
October 10, 2025 at 4:14 PM
Reposted by Melanie Bonhivers
cnrsbiologie.bsky.social
ResultatScientifique🔎| Le VIH profite d’une protéine humaine pour mieux s’installer dans notre ADN : une découverte qui ouvre de nouvelles pistes pour le combattre 🦠
✍️ Vincent Parissi
📕 @natmicrobiol.nature.com | buff.ly/Hqeu6kO
Un mécanisme clé de l’intégration du génome du VIH dans nos gènes élucidé
L’infection par le VIH-1 repose sur l’intégration du génome viral dans certaines régions riches en gènes.
www.insb.cnrs.fr
September 25, 2025 at 10:00 AM
Reposted by Melanie Bonhivers
bungoakiyoshi.bsky.social
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
First author of the paper Lim along with his PhD advisor. Congrats both!
September 19, 2025 at 11:22 AM
Reposted by Melanie Bonhivers
univbordeaux.bsky.social
🏅 Muriel Priault, chercheuse CNRS à l'IBGC*, a remporté le Prix Académique lors de la 10ᵉ édition de Cosmetic Victories, concours international organisé par la Cosmetic Valley. Ce prix distingue les projets de recherche les plus innovants dans le domaine cosmétique :
Muriel Priault, lauréate du prix Cosmetic Victories 2025 | CNRS Biologie
Muriel Priault, chercheuse CNRS, a remporté le Prix Académique lors de la 10ᵉ édition de Cosmetic Victories, un concours international organisé par la
www.insb.cnrs.fr
September 16, 2025 at 2:36 PM
Reposted by Melanie Bonhivers
fronzeslab.bsky.social
The results of the demo of the MINFLUX on our samples were stunning. It is unlikely that we will get such a system in the short term, but the good news is that we are ready for some proper high-res SMLM fun !
July 6, 2025 at 9:38 PM
Reposted by Melanie Bonhivers
abberior.rocks
#Trypanosoma, fixed, expanded, and imaged with #STED, stained for tubulin. Scale bar refers to expanded specimen, original structures are 3-3x smaller.
Image courtesy: @mbonhivers.bsky.social, MFP, CNRS, Univ. Bordeaux, France
#fluorescencefriday #ExM #STEDmicroscopy
June 27, 2025 at 9:31 AM
Reposted by Melanie Bonhivers
fronzeslab.bsky.social
Chaires de Professeur Junior (CPJ) 2025 www.mfp.cnrs.fr/wp/emploi/ch...
Chaires de Professeur Junior (CPJ) 2025 | Laboratoire de Microbiologie Fondamentale et Pathogénicité
Nom du projet : Virus Émergents et Changement Climatique Sections CNU : 64-65 Thématique scientifique : Biologie et santé Mots-clés : Sciences du système Terre et de l’Univers ; Environnement, … Conti...
www.mfp.cnrs.fr
June 18, 2025 at 11:10 AM
Reposted by Melanie Bonhivers
fronzeslab.bsky.social
Communication institutionnelle @univbordeaux.bsky.social à propos de la plateforme de #cryoEM @iecb.bsky.social
Deux nouveaux microscopes pour aller au cœur du vivant
La plateforme de cryo-microscopie électronique à l’Institut européen de chimie et biologie (IECB) est renforcée par l’acquisition de deux nouveaux microscopes, Glacios 2 et Talos L120. Ces équipements...
www.u-bordeaux.fr
June 10, 2025 at 3:34 PM
Reposted by Melanie Bonhivers
hakimi.bsky.social
🧵 Ever wondered what Toxoplasma is doing in your brain years after that undercooked steak 🥩 or a sip of contaminated water? Turns out, it's been hiding in your brain 🧠and we finally have a way to spot it. New study just dropped in EMBO Molecular Medicine 👇
doi.org/10.1038/s443...
Uncovering biomarkers for chronic toxoplasmosis detection highlights alternative pathways shaping parasite dormancy | EMBO Molecular Medicine
imageimageDespite their clinical relevance, bradyzoite-filled cysts - the hallmark of chronic toxoplasmosis - are largely overlooked in current diagnostics. This study highlights bradyzoite serologica...
doi.org
May 19, 2025 at 10:31 AM
Reposted by Melanie Bonhivers
iecb.bsky.social
We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to submit your application 🤓!!!
April 28, 2025 at 7:14 PM
Reposted by Melanie Bonhivers
cnrsbiologie.bsky.social
Une nouvelle cible thérapeutique contre la maladie du sommeil ? 🧬
Des chercheurs ont identifié une protéine clé chez le trypanosome, le parasite responsable.

🤝 @cnrsaquitaine.bsky.social @univbordeaux.bsky.social

buff.ly/lf9dYGp
Découverte d’une protéine d’intérêt chez le trypanosome vecteur de la maladie du sommeil
Trypanosoma brucei est un parasite responsable de graves maladies chez l’Homme et le bétail en Afrique.
www.insb.cnrs.fr
April 22, 2025 at 2:02 PM
Reposted by Melanie Bonhivers
parafrap.bsky.social
An ISWI-related chromatin remodeller regulates stage-specific gene expression in #Toxoplasma gondii. By Belen Pachano (ParaFrap PhD student) et al., team @hakimi.bsky.social. In @natmicrobiol.nature.com www.nature.com/articles/s41...
An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii - Nature Microbiology
Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...
www.nature.com
April 22, 2025 at 2:39 PM
Reposted by Melanie Bonhivers
iecb.bsky.social
We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!
April 14, 2025 at 8:57 AM
Reposted by Melanie Bonhivers
embl.org
1/ Last call for the EMBL-UNESCO Residency Programme! ⏳

If you’re a female African scientist working in infection biology, this is your opportunity to develop scientific skills while fostering collaboration across borders.

🙌 Apply until 31 March 2025.
www.embl.org/about/info/s...
March 25, 2025 at 8:51 AM
Reposted by Melanie Bonhivers
parafrap.bsky.social
💼 Associate Professor / Toxoplasma / Bordeaux-France

🎓 Teaching: animal biology, metazoan diversity & phylogeny (Bachelor 1,2,3)

🔬 Research: Apicomplexa parasites, focusing on Toxoplasma gondii. @ MFP Lab (UMR5234) @univbordeaux.bsky.social .

🗓️ Deadline: April 4

labex-parafrap.fr/en/job-offer...
Associate professor l Toxoplama l Bordeaux, France
    Associate Professor : Animal Biology and Parasitology – Host-Pathogen Interactions, Bordeaux, France  Teaching Profile ...
labex-parafrap.fr
March 11, 2025 at 9:42 AM
Reposted by Melanie Bonhivers
erc.europa.eu
#IWD2025 is an important day to celebrate women's social, economic, cultural & political achievements, but it's also a good occasion to call for gender equality.
The #SheFigures report on R&I describes the challenges women researchers face, but also highlights ideas to help them. 🔗 buff.ly/3EJDkB4
March 8, 2025 at 1:00 PM
Reposted by Melanie Bonhivers
derrickrrobinson.bsky.social
Assistant prof / MCF post available in ProParaCyto.
March 7, 2025 at 8:17 AM
Reposted by Melanie Bonhivers
academiesciences.bsky.social
📣Stand Up for Science !

En écho au mouvement américain "Stand Up For Science" et face aux menaces pesant sur nos institutions, France Inter a accueilli dans son 7/10 les scientifiques Alain Fisher, Valérie Masson-Delmotte et Olivier Berné.
March 5, 2025 at 9:12 AM
Reposted by Melanie Bonhivers
jcellsci.bsky.social
In her Essay, Renata Basto highlights the huge budget cuts facing the scientific community in France. In response to the cuts, a group of researchers has formed the ‘Pour une Recherche d'Avenir’ initiative to secure the future of French research.
journals.biologists.com/jcs/article/...
The importance of delivering Recherche d'Avenir – research for the future
In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...
journals.biologists.com
February 26, 2025 at 10:42 AM
Reposted by Melanie Bonhivers
parafrap.bsky.social
📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite
February 25, 2025 at 3:38 PM