Max Evrard
maxevrard.bsky.social
Max Evrard
@maxevrard.bsky.social
@arc-gov-au.bsky.social DECRA Fellow in @LMackayLab, @thedohertyinst.bsky.social | Immunologist | Interested about tissue #immunity
Reposted by Max Evrard
Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork!
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Matrix-producing neutrophils populate and shield the skin
Nature - A population of neutrophils in the skin produces extracellular matrix, providing a defence strategy by reinforcing the barrier properties of the skin and helping to block the entry of...
rdcu.be
March 19, 2025 at 9:28 PM
Reposted by Max Evrard
IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis: Immunity www.cell.com/immunity/ful...
IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis
Members of the interleukin-17 family are associated with tumor progression in various settings. Denk et al. find that, in colorectal cancer, IL-17RA switches from tumor promotion during early tumorige...
www.cell.com
February 28, 2025 at 10:11 PM
Reposted by Max Evrard
Our paper is out!
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity | Science Immunology www.science.org/doi/10.1126/...
LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity
LCK-mutant mice help define the role of LCK–co-receptor association in T cell development and immune responses.
www.science.org
February 21, 2025 at 10:32 PM
Reposted by Max Evrard
Now online! Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness
Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness
Mammary intraepithelial lymphocytes enhance mammary gland differentiation during pregnancy, thereby promoting offspring fitness.
dlvr.it
February 14, 2025 at 1:42 PM
Reposted by Max Evrard
How do T cells find the proper instructions to navigate tissues? In the Goldrath Lab @ucsdhealthsci.bsky.social, Amir Ferry mapped it out play-by-play. Potentiating these interactions strengthens the immunity cycle and enhances tumor control 1/n
New: Amir Ferry, Ananda Goldrath and colleagues @ucsdhealthsci.bsky.social show that differentiation of tissue-resident memory T cells (TRM) is accompanied by the upregulation of the conventional DC1 (cDC1) chemoattractant, Xcl1. https://buff.ly/4hrKCYe

#MucosalImmunology #TumorImmunology
January 22, 2025 at 6:53 PM
Reposted by Max Evrard
Today in @nature.com. We mapped the spatial and temporal dynamics of intestinal tissue-resident memory CD8 T (TRM) cell differentiation.
🔗 www.nature.com/articles/s41....
@ucsandiego.bsky.social @lji.org @alleninstitute.bsky.social @amonell.bsky.social @reinacampos.bsky.social @GoldrathLab 🧵 1/10
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted - Nature
Profiling of the location and transcriptome of tissue-resident memory CD8 T cell formation at single-transcript resolution finds regionalized signalling as the basis of immune diversity in t...
www.nature.com
January 22, 2025 at 4:15 PM
Reposted by Max Evrard
Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
December 19, 2024 at 9:30 PM
Reposted by Max Evrard
#Immunology by First release now @science.org

Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection

https://buff.ly/3DjNQ1e

By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
December 19, 2024 at 8:08 PM