Andres Hidalgo
@drusqui.bsky.social
I am excited to present our long-overdue lab website. Please visit us to learn who we are, our past work, and our current lines of research!
ahidalgolab.com
Thank you to Gerardo Barcia for his beautiful design and constant support in building it
ahidalgolab.com
Thank you to Gerardo Barcia for his beautiful design and constant support in building it
Hidalgo Lab | Mapping Innate Immunity
Research on neutrophil biology, innate immunity, and cardiovascular disease at Yale School of Medicine. Led by Dr. Andrés Hidalgo.
ahidalgolab.com
February 7, 2026 at 3:59 PM
I am excited to present our long-overdue lab website. Please visit us to learn who we are, our past work, and our current lines of research!
ahidalgolab.com
Thank you to Gerardo Barcia for his beautiful design and constant support in building it
ahidalgolab.com
Thank you to Gerardo Barcia for his beautiful design and constant support in building it
I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca
December 12, 2025 at 4:40 PM
I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca
Reposted by Andres Hidalgo
📰 Press Release: Researchers at @yaleschoolofmed.bsky.social have identified a way to suppress the daily fluctuations in the activity of key immune cells known as neutrophils. www.eurekalert.org/news-release...
See original paper from the @drusqui.bsky.social group: rupress.org/jem/article/...
See original paper from the @drusqui.bsky.social group: rupress.org/jem/article/...
December 12, 2025 at 4:30 PM
📰 Press Release: Researchers at @yaleschoolofmed.bsky.social have identified a way to suppress the daily fluctuations in the activity of key immune cells known as neutrophils. www.eurekalert.org/news-release...
See original paper from the @drusqui.bsky.social group: rupress.org/jem/article/...
See original paper from the @drusqui.bsky.social group: rupress.org/jem/article/...
What are #Neutrophils? why are there so many? how are they shaped by disease? how is it that they maintain memory despite their short lifespan?
Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇
authors.elsevier.com/a/1mFj9L7PXu...
Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇
authors.elsevier.com/a/1mFj9L7PXu...
authors.elsevier.com
December 11, 2025 at 8:39 PM
What are #Neutrophils? why are there so many? how are they shaped by disease? how is it that they maintain memory despite their short lifespan?
Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇
authors.elsevier.com/a/1mFj9L7PXu...
Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇
authors.elsevier.com/a/1mFj9L7PXu...
Reposted by Andres Hidalgo
Reposted by Andres Hidalgo
Fetal liver #macrophages support red blood cell production and pyrenocyte clearance in the developing embryo. Stifter, Greter et al. demonstrate that XPR1, a phosphate exporter and regulator, is required for the development and function of fetal liver macrophages. rupress.org/jem/article/...
December 3, 2025 at 6:00 PM
Fetal liver #macrophages support red blood cell production and pyrenocyte clearance in the developing embryo. Stifter, Greter et al. demonstrate that XPR1, a phosphate exporter and regulator, is required for the development and function of fetal liver macrophages. rupress.org/jem/article/...
Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.
I’m thrilled to introduce you to the NeuMap! our latest work in@nature.com. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour de force www.nature.com/articles/s41...
Architecture of the neutrophil compartment - Nature
Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and ...
www.nature.com
December 3, 2025 at 6:57 PM
Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.
Reposted by Andres Hidalgo
Thrilled to share our Perspective on structural immunity, where we discuss how immune cells double as architects, weaving and reshaping the fabric of our tissues. Grateful to @drusqui.bsky.social, all co-authors, and the wonderful @natrevimmunol.nature.com team for making it such a joy to write!
NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM
#structuralimmunity #immunosky
#structuralimmunity #immunosky
Structural immunity: immune cells as architects of tissue barriers - Nature Reviews Immunology
This Perspective presents a framework of ‘structural immunity’ that positions immune cells as architects of tissue structure. Beyond their roles in antimicrobial defence, we posit that immune cells co...
www.nature.com
October 28, 2025 at 7:54 PM
Thrilled to share our Perspective on structural immunity, where we discuss how immune cells double as architects, weaving and reshaping the fabric of our tissues. Grateful to @drusqui.bsky.social, all co-authors, and the wonderful @natrevimmunol.nature.com team for making it such a joy to write!
Here is a full-text access to a view-only version of the paper:
rdcu.be/eM7xA
rdcu.be/eM7xA
October 28, 2025 at 4:43 PM
Here is a full-text access to a view-only version of the paper:
rdcu.be/eM7xA
rdcu.be/eM7xA
Thank you to our editor, Kirsty Minton, and the staff at NRI for the opportunity to share our thoughts on this emerging topic.
NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM
#structuralimmunity #immunosky
#structuralimmunity #immunosky
Structural immunity: immune cells as architects of tissue barriers - Nature Reviews Immunology
This Perspective presents a framework of ‘structural immunity’ that positions immune cells as architects of tissue structure. Beyond their roles in antimicrobial defence, we posit that immune cells co...
www.nature.com
October 28, 2025 at 4:41 PM
Thank you to our editor, Kirsty Minton, and the staff at NRI for the opportunity to share our thoughts on this emerging topic.
Reposted by Andres Hidalgo
Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published @jem.org with Saira Ambreen, Afshan McCarthy and @drusqui.bsky.social
rupress.org/jem/article/...
rupress.org/jem/article/...
Heart of the matter: Neutrophils, cancer, and cardiovascular disease | Journal of Experimental Medicine | Rockefeller University Press
Cancer and cardiovascular disease are the leading causes of death worldwide. Cancer patients display an abnormally elevated burden of cardiovascular diseas
rupress.org
August 12, 2025 at 12:47 PM
Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published @jem.org with Saira Ambreen, Afshan McCarthy and @drusqui.bsky.social
rupress.org/jem/article/...
rupress.org/jem/article/...
Reposted by Andres Hidalgo
🚨 Our new study is live in The Lancet Microbe!
“The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study” Led by @jaycrandell.bsky.social , Valter Monteiro and Lauren Pischel
www.sciencedirect.com/science/arti...
A thread 🧵!
“The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study” Led by @jaycrandell.bsky.social , Valter Monteiro and Lauren Pischel
www.sciencedirect.com/science/arti...
A thread 🧵!
The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study
Cross-reactive immune memory responses to orthopoxviruses in humans remain poorly characterised despite their relevance for vaccine design and outbrea…
www.sciencedirect.com
April 28, 2025 at 7:01 PM
🚨 Our new study is live in The Lancet Microbe!
“The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study” Led by @jaycrandell.bsky.social , Valter Monteiro and Lauren Pischel
www.sciencedirect.com/science/arti...
A thread 🧵!
“The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study” Led by @jaycrandell.bsky.social , Valter Monteiro and Lauren Pischel
www.sciencedirect.com/science/arti...
A thread 🧵!
Reposted by Andres Hidalgo
OBS #Immunology Seminar
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
April 3, 2025 at 4:20 PM
OBS #Immunology Seminar
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
Reposted by Andres Hidalgo
Nature research paper: Matrix-producing neutrophils populate and shield the skin
https://go.nature.com/4iJSgy5
https://go.nature.com/4iJSgy5
Matrix-producing neutrophils populate and shield the skin - Nature
A population of neutrophils in the skin produces extracellular matrix, providing a defence strategy by reinforcing the barrier properties of the skin and helping to block the entry of pathogens.
go.nature.com
March 21, 2025 at 11:00 AM
Nature research paper: Matrix-producing neutrophils populate and shield the skin
https://go.nature.com/4iJSgy5
https://go.nature.com/4iJSgy5
Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork!
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Matrix-producing neutrophils populate and shield the skin
Nature - A population of neutrophils in the skin produces extracellular matrix, providing a defence strategy by reinforcing the barrier properties of the skin and helping to block the entry of...
rdcu.be
March 19, 2025 at 9:28 PM
Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork!
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...