Leon-Samuel Icking
@lsi.bsky.social
PhD student from the Kalmbach Lab in Neuchâtel
flowerpunk 🏵️ + solarpunk ☀
Anything SynBio (and Plants 👀)!
iGEM Freiburg Ultra🤘
Chaotic neutral
flowerpunk 🏵️ + solarpunk ☀
Anything SynBio (and Plants 👀)!
iGEM Freiburg Ultra🤘
Chaotic neutral
Pinned
If iGEM Freiburg has 100 fans, I'm one of them.
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
If they have 10 fans, I'm one of them.
If they have one fan, I'm that fan.
If they have 0 fans, I'm dead.
@biologyunifreiburg.bsky.social @cibss.bsky.social
Reposted by Leon-Samuel Icking
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 21, 2025 at 5:32 PM
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
Reposted by Leon-Samuel Icking
A few py2Dmol updates 🧬
py2dmol.solab.org
Integration with AlphaFoldDB (will auto fetch results). Drag and drop results from AF3-server or ColabFold for interactive experience! (1/4)
py2dmol.solab.org
Integration with AlphaFoldDB (will auto fetch results). Drag and drop results from AF3-server or ColabFold for interactive experience! (1/4)
November 19, 2025 at 8:15 AM
A few py2Dmol updates 🧬
py2dmol.solab.org
Integration with AlphaFoldDB (will auto fetch results). Drag and drop results from AF3-server or ColabFold for interactive experience! (1/4)
py2dmol.solab.org
Integration with AlphaFoldDB (will auto fetch results). Drag and drop results from AF3-server or ColabFold for interactive experience! (1/4)
Reposted by Leon-Samuel Icking
Our new paper is published in the Journal of Chemical Biology! 🏮 We share StayRose, a red version of StayGold 🏮 StayRose has an unnatural amino acid-based chromophore, and has the same immense photobleach-resistance as StayGold 💡
StayRose: A photostable StayGold derivative redshifted by genetic code expansion
Photobleaching of fluorescent proteins often limits the acquisition of high-quality
images in microscopy. StayGold, a novel dimeric GFP recently monomerized through sequence
engineering, addresses thi...
www.jbc.org
November 17, 2025 at 9:03 AM
Our new paper is published in the Journal of Chemical Biology! 🏮 We share StayRose, a red version of StayGold 🏮 StayRose has an unnatural amino acid-based chromophore, and has the same immense photobleach-resistance as StayGold 💡
Reposted by Leon-Samuel Icking
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 17, 2025 at 8:51 AM
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Reposted by Leon-Samuel Icking
New OA Article: "Cambium LBDs promote radial growth by regulating PLL-mediated pectin metabolism" rdcu.be/eP4mp
LBD TFs in the cambium drive radial plant growth by regulating PECTATE LYASE-LIKE (PLL) enzymes that remodel cell wall pectin, promoting cell expansion.
LBD TFs in the cambium drive radial plant growth by regulating PECTATE LYASE-LIKE (PLL) enzymes that remodel cell wall pectin, promoting cell expansion.
November 15, 2025 at 12:14 PM
New OA Article: "Cambium LBDs promote radial growth by regulating PLL-mediated pectin metabolism" rdcu.be/eP4mp
LBD TFs in the cambium drive radial plant growth by regulating PECTATE LYASE-LIKE (PLL) enzymes that remodel cell wall pectin, promoting cell expansion.
LBD TFs in the cambium drive radial plant growth by regulating PECTATE LYASE-LIKE (PLL) enzymes that remodel cell wall pectin, promoting cell expansion.
Reposted by Leon-Samuel Icking
Holy shit.
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
November 15, 2025 at 1:41 PM
Holy shit.
Reposted by Leon-Samuel Icking
Arabidopsis p35s-NLS-myc tag and p35S-NLS-TbID-GFP lines NEEDED! Is someone able to share with me or with your community? Plasmid constructs are also fine. Please please 🙏 #arabidopsis
November 15, 2025 at 11:27 AM
Arabidopsis p35s-NLS-myc tag and p35S-NLS-TbID-GFP lines NEEDED! Is someone able to share with me or with your community? Plasmid constructs are also fine. Please please 🙏 #arabidopsis
Reposted by Leon-Samuel Icking
Great opportunity to join Freiburg University as a Postdoc from abroad! Happy to help !
If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 14, 2025 at 7:16 AM
Great opportunity to join Freiburg University as a Postdoc from abroad! Happy to help !
Reposted by Leon-Samuel Icking
And Freiburg is gorgeous, friendly, and fun. Not to mention full of excellent plant scientists 💚
Stuck in the US as a postdoc due to the current political nightmare? Consider to join us in Freiburg @dompsfr.bsky.social @biologyunifreiburg.bsky.social #plantscience
If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
November 13, 2025 at 9:37 PM
And Freiburg is gorgeous, friendly, and fun. Not to mention full of excellent plant scientists 💚
Reposted by Leon-Samuel Icking
breaking!!!!!!! spider web!!!!!!!! news!!!!!!!!
defector.com/drop-whateve...
defector.com/drop-whateve...
Drop Whatever You're Doing Right This Instant, There's Big Spider Web News | Defector
After a brief foray into creatures big, flashy, and famous, we must return to form and focus on the spineless, creepy, and crawling. Today we’re shining a spotlight on one of the most loathèd creepy-c...
defector.com
November 13, 2025 at 5:01 PM
breaking!!!!!!! spider web!!!!!!!! news!!!!!!!!
defector.com/drop-whateve...
defector.com/drop-whateve...
Reposted by Leon-Samuel Icking
Our University @uni-freiburg.de with @friasunifreiburg.bsky.social has also just lunched this initiative for rescuing ECR scientists in needs. uni-freiburg.de/frias/call-f.... Our lab can host a 🌱 fellow.
November 13, 2025 at 4:40 PM
Our University @uni-freiburg.de with @friasunifreiburg.bsky.social has also just lunched this initiative for rescuing ECR scientists in needs. uni-freiburg.de/frias/call-f.... Our lab can host a 🌱 fellow.
Reposted by Leon-Samuel Icking
Stuck in the US as a postdoc due to the current political nightmare? Consider to join us in Freiburg @dompsfr.bsky.social @biologyunifreiburg.bsky.social #plantscience
If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 13, 2025 at 4:28 PM
Stuck in the US as a postdoc due to the current political nightmare? Consider to join us in Freiburg @dompsfr.bsky.social @biologyunifreiburg.bsky.social #plantscience
Reposted by Leon-Samuel Icking
If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 13, 2025 at 12:31 PM
If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
uni-freiburg.de/frias/call-f...
Our lab in Freiburg can also serve as a host — happy to discuss options.
Reposted by Leon-Samuel Icking
Reposted by Leon-Samuel Icking
Now online in its final version. Plz surf to doi.org/10.1111/tpj....
November 12, 2025 at 9:29 PM
Now online in its final version. Plz surf to doi.org/10.1111/tpj....
Reposted by Leon-Samuel Icking
Very happy to share our recent work @cultivarium.bsky.social on genetic tools for Ideonella sakaiensis, a (Betaproteo-)bacterium that degrades PET plastic.
We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.
We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.
November 12, 2025 at 7:05 PM
Very happy to share our recent work @cultivarium.bsky.social on genetic tools for Ideonella sakaiensis, a (Betaproteo-)bacterium that degrades PET plastic.
We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.
We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.
Reposted by Leon-Samuel Icking
🚨Job Alert!! Assistant professor vacancy ‘plant abiotic stress resilience’ in our group @uuplants.bsky.social Come for the science, stay for the amazing colleagues 😀More details here www.uu.nl/en/organisat... Please share!!
September 3, 2025 at 5:37 PM
🚨Job Alert!! Assistant professor vacancy ‘plant abiotic stress resilience’ in our group @uuplants.bsky.social Come for the science, stay for the amazing colleagues 😀More details here www.uu.nl/en/organisat... Please share!!
Reposted by Leon-Samuel Icking
🚨Job Alert!! Assistant professor vacancy ‘plant abiotic stress resilience’ in our group @uuplants.bsky.social Come for the science, stay for the amazing colleagues 😀More details here www.uu.nl/en/organisat... Please share!!
November 12, 2025 at 3:31 PM
Reposted by Leon-Samuel Icking
You are embarrassing yourself by lauding this monster. Do you defend these views, which he held lifelong. Where is the "nuance in these words?" Shame!
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
November 8, 2025 at 12:37 PM
You are embarrassing yourself by lauding this monster. Do you defend these views, which he held lifelong. Where is the "nuance in these words?" Shame!
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
Reposted by Leon-Samuel Icking
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Illuminating plant immunity: A live sensor to watch salicylic acid in action | Plantae
Salicylic acid (SA) is best known as a central hormone orchestrating plant immune response, including the hypersensitive reaction and systemic acquired resistance. Beyond defense…
buff.ly
November 7, 2025 at 9:15 PM
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Reposted by Leon-Samuel Icking
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social
www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
Congratz to @reneinckemann.bsky.social and team! Long time in the oven!
New OA Article: "A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas" rdcu.be/eOdZP
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
Modular-cloning-based platform for high-throughput chloroplast engineering in Chlamydomonas reinhardtii.
November 6, 2025 at 9:54 PM
Congratz to @reneinckemann.bsky.social and team! Long time in the oven!
Reposted by Leon-Samuel Icking
Arabidopsis, a little weed in the mustard family, joined the celebrity ranks of Drosophila, E. coli and other model organisms in the 1980s. There was a lot of pushback-- in some circles it was referred to as the "A-word" (!)
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
How a humble weed became a superstar of biology
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
knowmag.org
November 4, 2025 at 4:00 PM
Arabidopsis, a little weed in the mustard family, joined the celebrity ranks of Drosophila, E. coli and other model organisms in the 1980s. There was a lot of pushback-- in some circles it was referred to as the "A-word" (!)
1 done - 23 to go
November 4, 2025 at 12:05 PM
1 done - 23 to go
Reposted by Leon-Samuel Icking
My new Emmy Noether Group is recruiting!
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
Aktuelle Ausschreibungen
Aktuelle Ausschreibungen
www.uni-kiel.de
November 3, 2025 at 9:03 AM
My new Emmy Noether Group is recruiting!
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
🔬 Two PhD positions in plant pathogen evolution
🧬 Start: April 2026 (flexible)
📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de
⏰ Apply by 15 Dec 2025
🔗 More info: www.uni-kiel.de/personal/de/...
Do get in touch or share 😊