Dr. Fiona
@fionachembot.bsky.social
she/her; I use computers to study chemistry! Junior Professor in the Institute of Physical Chemistry at Albert-Ludwigs Universität Freiburg!
Pinned
Dr. Fiona
@fionachembot.bsky.social
· Mar 13
D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes
The SARS-CoV-2 spike glycoprotein binds human epithelial cells and enables infection through a key conformational transition that exposes its receptor binding domain (RBD). Experimental evidence indic...
www.biorxiv.org
Nevertheless, we persisted ❤️
📣 NEW BIORXIV ALERT!! 🚨
Using WE MD, linguistic pathway clustering, dynamical network analyses, and HDXMS we reveal a hidden allosteric network within the SARS2 spike S1 domain and predict how the D614G mutation impacts this network!
www.biorxiv.org/content/10.1...
📣 NEW BIORXIV ALERT!! 🚨
Using WE MD, linguistic pathway clustering, dynamical network analyses, and HDXMS we reveal a hidden allosteric network within the SARS2 spike S1 domain and predict how the D614G mutation impacts this network!
www.biorxiv.org/content/10.1...
Reposted by Dr. Fiona
This work started as a bachelor project and @1nussi1.bsky.social and @felixgrunberger.bsky.social showed that CsmR is a very interesting regulator important for controlling motiliy and cellshape in Haloferax volcanii.
The preprint is out now: www.biorxiv.org/content/10.6...
The preprint is out now: www.biorxiv.org/content/10.6...
www.biorxiv.org
February 4, 2026 at 9:34 AM
This work started as a bachelor project and @1nussi1.bsky.social and @felixgrunberger.bsky.social showed that CsmR is a very interesting regulator important for controlling motiliy and cellshape in Haloferax volcanii.
The preprint is out now: www.biorxiv.org/content/10.6...
The preprint is out now: www.biorxiv.org/content/10.6...
Americans are already working DURING high school, Americans are already delaying retirement, most have NO retirement savings. Most ALREADY work SEVERAL jobs. This is absolute nonsense.
Taxing a handful of billionaires would more than remove debt.
This is pointless blame-gaming. Don't fall for it.
Taxing a handful of billionaires would more than remove debt.
This is pointless blame-gaming. Don't fall for it.
Dr Oz: "If we could get the average American to start working a year earlier, right out of high school, or a year later -- not retire -- or work better during their lifetime because they're healthy, it would generate about $3 trillion to the US economy. That would more than remove the debt."
February 3, 2026 at 9:11 AM
Americans are already working DURING high school, Americans are already delaying retirement, most have NO retirement savings. Most ALREADY work SEVERAL jobs. This is absolute nonsense.
Taxing a handful of billionaires would more than remove debt.
This is pointless blame-gaming. Don't fall for it.
Taxing a handful of billionaires would more than remove debt.
This is pointless blame-gaming. Don't fall for it.
No one is illegal on stolen land built by stolen hands.
February 2, 2026 at 9:03 AM
No one is illegal on stolen land built by stolen hands.
(the bill was literally 1/10th of what i was expecting... I know its the lease of the USs problems at the moment but good god)
January 31, 2026 at 9:11 PM
(the bill was literally 1/10th of what i was expecting... I know its the lease of the USs problems at the moment but good god)
As an American, opening up my first bill from a doctors appointment was an absolute ROLLER COASTER ride.
January 31, 2026 at 9:11 PM
As an American, opening up my first bill from a doctors appointment was an absolute ROLLER COASTER ride.
Reposted by Dr. Fiona
The research of Dr. Gladys West, who died Jan. 17 at 95, laid the groundwork for the GPS.
Thanks in part to her, anyone with a smartphone can navigate easily from one place to the next, without having to stop to ask for directions.
Thanks in part to her, anyone with a smartphone can navigate easily from one place to the next, without having to stop to ask for directions.
Mathematician Gladys West dies at 95. She was a hidden figure behind GPS.
Without the mathematical model that she helped refine, “the extraordinary positioning, navigation, and timing accuracy of GPS would be impossible to achieve.”
www.washingtonpost.com
January 31, 2026 at 8:30 PM
The research of Dr. Gladys West, who died Jan. 17 at 95, laid the groundwork for the GPS.
Thanks in part to her, anyone with a smartphone can navigate easily from one place to the next, without having to stop to ask for directions.
Thanks in part to her, anyone with a smartphone can navigate easily from one place to the next, without having to stop to ask for directions.
when will this horror end...
Billions for an organisation full of nonces who've had over 5,000 complaints of sexual assault against minors back in 2019, the world knew this was happening during Trump's first term. A nazi pedophile organisation is getting billions so they can keep molesting.
www.theguardian.com/us-news/2019...
www.theguardian.com/us-news/2019...
January 31, 2026 at 7:26 PM
when will this horror end...
Reposted by Dr. Fiona
Two Democratic members of Congress attacked in three days. Maxwell Frost was assaulted on Saturday, Ilan Omar tonight.
January 28, 2026 at 2:03 AM
Two Democratic members of Congress attacked in three days. Maxwell Frost was assaulted on Saturday, Ilan Omar tonight.
Just submitted my first manuscript as an independent PI
January 27, 2026 at 9:40 PM
Just submitted my first manuscript as an independent PI
No words, just tears and a broken heart.
Rest in Peace Alex Jeffrey Pretti🙏🏾 The VA ICU Nurses send him off right 💔
January 27, 2026 at 12:16 PM
No words, just tears and a broken heart.
yes its quite tough, it was a hard weekend. my mom is a nurse and my dad is a frequent protester, i just kept thinking this could easily have been them.
On one hand I feel helpless but on another hand I feel so proud of the Americans who are protesting, ill continue to use my voice from here
On one hand I feel helpless but on another hand I feel so proud of the Americans who are protesting, ill continue to use my voice from here
January 26, 2026 at 10:11 AM
yes its quite tough, it was a hard weekend. my mom is a nurse and my dad is a frequent protester, i just kept thinking this could easily have been them.
On one hand I feel helpless but on another hand I feel so proud of the Americans who are protesting, ill continue to use my voice from here
On one hand I feel helpless but on another hand I feel so proud of the Americans who are protesting, ill continue to use my voice from here
Yes this is a Science account, but its also a political account because we can't do science if ICE shoots us in the street for protecting our fellow humans.
January 26, 2026 at 8:59 AM
Yes this is a Science account, but its also a political account because we can't do science if ICE shoots us in the street for protecting our fellow humans.
Reposted by Dr. Fiona
Wife and I in tears reading this…
January 26, 2026 at 4:30 AM
Wife and I in tears reading this…
While attempting to sleep last night I remembered the scene in Jojo Rabbit where jojo finds his mom's feet hanging above his head in the street. i thought to myself "well at least we aren't there" and then one word came to mind "YET".
Here leads to there.
Now will become then.
Unless we act.
Here leads to there.
Now will become then.
Unless we act.
January 25, 2026 at 8:14 PM
While attempting to sleep last night I remembered the scene in Jojo Rabbit where jojo finds his mom's feet hanging above his head in the street. i thought to myself "well at least we aren't there" and then one word came to mind "YET".
Here leads to there.
Now will become then.
Unless we act.
Here leads to there.
Now will become then.
Unless we act.
Reposted by Dr. Fiona
Different uniforms. Same kneeling man. Same rifles. Same state telling the world this is order. History does not repeat politely. It reuses its favorite methods. If you think this is exaggerated, you are standing in the second photo.
January 25, 2026 at 4:10 PM
Different uniforms. Same kneeling man. Same rifles. Same state telling the world this is order. History does not repeat politely. It reuses its favorite methods. If you think this is exaggerated, you are standing in the second photo.
Reposted by Dr. Fiona
DHS has shot 12 people during immigration enforcement operations since September:
January 25, 2026 at 4:27 PM
DHS has shot 12 people during immigration enforcement operations since September:
"guns dont kill people, federal agents kill people"
January 24, 2026 at 7:52 PM
"guns dont kill people, federal agents kill people"
Reposted by Dr. Fiona
"What we’re … seeing is the toll of the uncertainty."
My latest story for @science.org—part of a package that explores how the U.S. scientific community has changed under Trump—includes new numbers on graduate enrollment and faculty hiring.
www.science.org/content/arti...
My latest story for @science.org—part of a package that explores how the U.S. scientific community has changed under Trump—includes new numbers on graduate enrollment and faculty hiring.
www.science.org/content/arti...
January 22, 2026 at 9:12 PM
"What we’re … seeing is the toll of the uncertainty."
My latest story for @science.org—part of a package that explores how the U.S. scientific community has changed under Trump—includes new numbers on graduate enrollment and faculty hiring.
www.science.org/content/arti...
My latest story for @science.org—part of a package that explores how the U.S. scientific community has changed under Trump—includes new numbers on graduate enrollment and faculty hiring.
www.science.org/content/arti...
not me asking ChatGPT if anyone is mad at me
January 23, 2026 at 1:46 PM
not me asking ChatGPT if anyone is mad at me
And when all the dust settles and we (the US) are on the path to rebuilding our (US) reputation, some will say "We really just didnt know what was happening" I want EVERYONE to be ready to say "BULL-F*CKING-SHIT" because all of this is playing out in 1080p
(please *do not* excuse my language)
(please *do not* excuse my language)
There is going to come a time in your life when you are chatting with a guy, at a barbecue or something, a new coworker maybe, a dad at school drop off, and he tells you he used to be in ICE. You’re going to need to spit on that guy
Minnesota: "School officials say the [5-year-old] child was used as bait. They say [ICE] agents made little Liam knock on the door to ask to be let in in order to see if anyone else was home."
January 22, 2026 at 8:58 AM
And when all the dust settles and we (the US) are on the path to rebuilding our (US) reputation, some will say "We really just didnt know what was happening" I want EVERYONE to be ready to say "BULL-F*CKING-SHIT" because all of this is playing out in 1080p
(please *do not* excuse my language)
(please *do not* excuse my language)
Reposted by Dr. Fiona
There is going to come a time in your life when you are chatting with a guy, at a barbecue or something, a new coworker maybe, a dad at school drop off, and he tells you he used to be in ICE. You’re going to need to spit on that guy
Minnesota: "School officials say the [5-year-old] child was used as bait. They say [ICE] agents made little Liam knock on the door to ask to be let in in order to see if anyone else was home."
January 22, 2026 at 2:27 AM
There is going to come a time in your life when you are chatting with a guy, at a barbecue or something, a new coworker maybe, a dad at school drop off, and he tells you he used to be in ICE. You’re going to need to spit on that guy
soooo Minnesota leading the revolution orrrrr?
January 21, 2026 at 7:57 PM
soooo Minnesota leading the revolution orrrrr?
Hallo 👋 ich bin's!!
Herzlich willkommen! Seit Oktober 2025 ist Dr. Fiona Kearns @fionachembot.bsky.social Juniorprofessorin für Theoretische #Chemie & Chemische #Datenwissenschaften. Im Interview erklärt die US-Amerikanerin, wie ihre Forschung dazu beiträgt, #Krankheiten besser zu verstehen.
ufr.link/neuberufen-kearns
ufr.link/neuberufen-kearns
January 20, 2026 at 9:41 AM
Hallo 👋 ich bin's!!
Im rooting for Bad Bunny this super bowl season
January 19, 2026 at 8:21 AM
Im rooting for Bad Bunny this super bowl season
The only thing the US can recycle is fascism
January 16, 2026 at 1:04 PM
The only thing the US can recycle is fascism