Eva Dvorak Tomastikova
@evadt.bsky.social
Scientist working on DNA damage repair in plants
Chromatin organization and function group of Aleš Pečinka
Chromatin organization and function group of Aleš Pečinka
Reposted by Eva Dvorak Tomastikova
Our paper is out in @nature.com! Oncogenes are often copy-number amplified on extrachromosomal DNA (ecDNA) in cancer, but how is ecDNA inherited by dividing cells? Here we identified elements within ecDNA that promote its retention in dividing cells. 1/11
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Genetic elements promote retention of extrachromosomal DNA in cancer cells - Nature
A combination of genome-wide functional screening, imaging and chromatin profiling identifies a new class of highly prevalent genomic elements that help retain extrachromosomal DNA copies in dividing ...
www.nature.com
November 19, 2025 at 7:03 PM
Our paper is out in @nature.com! Oncogenes are often copy-number amplified on extrachromosomal DNA (ecDNA) in cancer, but how is ecDNA inherited by dividing cells? Here we identified elements within ecDNA that promote its retention in dividing cells. 1/11
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Eva Dvorak Tomastikova
Reposted by Eva Dvorak Tomastikova
Latest research from the Bäurle lab on the function of our favourite memory TF - HSFA2!
Promoter and domain swap analysis delineates heat stress memory-specific determinants of heat shock factor HSFA2
The function of the transcription factor HSFA2 in heat-stress induced transcriptional memory maps to functional domains within the protein.
academic.oup.com
November 16, 2025 at 8:57 AM
Latest research from the Bäurle lab on the function of our favourite memory TF - HSFA2!
Arabidopsis p35s-NLS-myc tag and p35S-NLS-TbID-GFP lines NEEDED! Is someone able to share with me or with your community? Plasmid constructs are also fine. Please please 🙏 #arabidopsis
November 15, 2025 at 11:27 AM
Arabidopsis p35s-NLS-myc tag and p35S-NLS-TbID-GFP lines NEEDED! Is someone able to share with me or with your community? Plasmid constructs are also fine. Please please 🙏 #arabidopsis
Reposted by Eva Dvorak Tomastikova
New online: AlphaSync is an enhanced AlphaFold structure database synchronized with UniProt
AlphaSync is an enhanced AlphaFold structure database synchronized with UniProt
Nature Structural & Molecular Biology, Published online: 11 November 2025; doi:10.1038/s41594-025-01719-xAlphaSync synchronizes AlphaFold Protein Structure Database predictions with UniProt sequences, providing up-to-date protein structures with residue-level annotations for humans, model organisms and pathogens through an accessible web interface and application programming interface.
go.nature.com
November 12, 2025 at 8:35 AM
New online: AlphaSync is an enhanced AlphaFold structure database synchronized with UniProt
Reposted by Eva Dvorak Tomastikova
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Postdoctoral Researcher (Dr Miguel Montez) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Wellcome Trust project led by Dr Miguel Montez and hosted within the Dodd Group at the John Innes Centre.
www.jic.ac.uk
November 13, 2025 at 8:34 AM
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Reposted by Eva Dvorak Tomastikova
PhD positions!
For next year (deadline 15th april 2026, start date ~september 2026), we are looking for 15 PhD students for AGILE: "Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells"
cordis.europa.eu/project/id/1...
please repost!
www.photobodies.com/about-6
For next year (deadline 15th april 2026, start date ~september 2026), we are looking for 15 PhD students for AGILE: "Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells"
cordis.europa.eu/project/id/1...
please repost!
www.photobodies.com/about-6
Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells | AGILE | Project | Fact Sheet | HORIZON | CORDIS | European Commission
Quantitative microscopy imaging holds transformative potential in plant sciences by uncovering structural and functional principles at unprecedented spatial and temporal scale revealing how plants adapt their growth and physiology to environmental changes. Despite its promise...
cordis.europa.eu
November 10, 2025 at 4:28 PM
PhD positions!
For next year (deadline 15th april 2026, start date ~september 2026), we are looking for 15 PhD students for AGILE: "Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells"
cordis.europa.eu/project/id/1...
please repost!
www.photobodies.com/about-6
For next year (deadline 15th april 2026, start date ~september 2026), we are looking for 15 PhD students for AGILE: "Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells"
cordis.europa.eu/project/id/1...
please repost!
www.photobodies.com/about-6
Reposted by Eva Dvorak Tomastikova
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Reposted by Eva Dvorak Tomastikova
🚀 Exciting news for the imaging community!
The EMBO Practical Course – Hack Your Microscope is coming to ITQB NOVA (Oeiras, Portugal) on April 20–25, 2026 🧠🔬
👉 Course details & registration: meetings.embo.org/event/26-mic...
#Microscopy #OpenScience #Bioimaging #EMBOmicroscope
The EMBO Practical Course – Hack Your Microscope is coming to ITQB NOVA (Oeiras, Portugal) on April 20–25, 2026 🧠🔬
👉 Course details & registration: meetings.embo.org/event/26-mic...
#Microscopy #OpenScience #Bioimaging #EMBOmicroscope
November 10, 2025 at 9:10 AM
🚀 Exciting news for the imaging community!
The EMBO Practical Course – Hack Your Microscope is coming to ITQB NOVA (Oeiras, Portugal) on April 20–25, 2026 🧠🔬
👉 Course details & registration: meetings.embo.org/event/26-mic...
#Microscopy #OpenScience #Bioimaging #EMBOmicroscope
The EMBO Practical Course – Hack Your Microscope is coming to ITQB NOVA (Oeiras, Portugal) on April 20–25, 2026 🧠🔬
👉 Course details & registration: meetings.embo.org/event/26-mic...
#Microscopy #OpenScience #Bioimaging #EMBOmicroscope
Reposted by Eva Dvorak Tomastikova
🧬 List of 2026 DNA repair and genome stability conferences, now updated. Please let me know if there is anything missing!
docs.google.com/spreadsheets...
docs.google.com/spreadsheets...
DNA REPAIR/GENOME STABILITY CONFERENCES
docs.google.com
November 9, 2025 at 10:33 PM
🧬 List of 2026 DNA repair and genome stability conferences, now updated. Please let me know if there is anything missing!
docs.google.com/spreadsheets...
docs.google.com/spreadsheets...
Reposted by Eva Dvorak Tomastikova
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Illuminating plant immunity: A live sensor to watch salicylic acid in action | Plantae
Salicylic acid (SA) is best known as a central hormone orchestrating plant immune response, including the hypersensitive reaction and systemic acquired resistance. Beyond defense…
buff.ly
November 7, 2025 at 9:15 PM
Plant Science Research Weekly -- Illuminating plant immunity: a live sensor to watch salicylic acid in action (Science) @bijuntang.bsky.social @xanderjones.bsky.social @botanicaljim.bsky.social @philcarella.bsky.social (Summary by Ching Chan) buff.ly/SF8nZ9R
#PlantaePSRW
#PlantaePSRW
Reposted by Eva Dvorak Tomastikova
From Knowable Magazine: How #Arabidopsis thaliana, a humble weed, became a superstar of plant biology | Knowable Magazine knowablemagazine.org/content/arti...
How a humble weed became a superstar of biology
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
knowablemagazine.org
November 5, 2025 at 4:54 PM
From Knowable Magazine: How #Arabidopsis thaliana, a humble weed, became a superstar of plant biology | Knowable Magazine knowablemagazine.org/content/arti...
Reposted by Eva Dvorak Tomastikova
Ancient DNA studies usually link changes in lifestyle and language in the past to population movements. But not always! A new study in @nature.com reveals a South American ancestry that stayed steady for 8,500 years, despite major cultural and linguistic shifts. @science.org 🏺 🧬
Mystery group lived in central Argentina for millennia, ancient DNA reveals
New study fills major gap in genetic map of ancient human migrations
www.science.org
November 5, 2025 at 4:34 PM
Ancient DNA studies usually link changes in lifestyle and language in the past to population movements. But not always! A new study in @nature.com reveals a South American ancestry that stayed steady for 8,500 years, despite major cultural and linguistic shifts. @science.org 🏺 🧬
Reposted by Eva Dvorak Tomastikova
ICYMI: New Online! Decoding ubiquitin signals inside cells
Decoding ubiquitin signals inside cells
Nature Reviews Molecular Cell Biology, Published online: 31 October 2025; doi:10.1038/s41580-025-00919-zIn this Tools of the Trade article, Kiss (Schulman lab) discusses the development of UbiREAD, a method that delivers in vitro-ubiquitinated protein reporters into cells to systematically assess how different ubiquitin chain configurations affect protein stability and degradation.
bit.ly
November 3, 2025 at 5:06 PM
ICYMI: New Online! Decoding ubiquitin signals inside cells
Reposted by Eva Dvorak Tomastikova
How to scare a researcher!
October 30, 2025 at 6:00 AM
How to scare a researcher!
Reposted by Eva Dvorak Tomastikova
New lab / new life 🌱
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
October 29, 2025 at 2:46 PM
New lab / new life 🌱
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
Reposted by Eva Dvorak Tomastikova
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by Eva Dvorak Tomastikova
Genetically engineered color-changing Arabidopsis 🧬📷- attempt #3
I think I finally nailed it with this one.
I think I finally nailed it with this one.
October 27, 2025 at 11:53 AM
Genetically engineered color-changing Arabidopsis 🧬📷- attempt #3
I think I finally nailed it with this one.
I think I finally nailed it with this one.
Reposted by Eva Dvorak Tomastikova
Reposted by Eva Dvorak Tomastikova
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
October 24, 2025 at 9:04 AM
Do you want to do a Masters in Evolutionary Biology? The call for applying to the MEME program is now open! MEME is a fantastic 2-year MSc between four European Universities on all areas of Evolutionary Biology. Apply and study in Sweden/France/the Netherlands/Germany/USA/Switzerland! www.evobio.eu
Reposted by Eva Dvorak Tomastikova
"...researchers who invest time in their students tend to lead more-productive, more-collaborative groups and attract stronger future students than those who do not." "Time spent with the next generation of scientists is an investment."
www.nature.com/articles/d41...
www.nature.com/articles/d41...
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
www.nature.com
October 24, 2025 at 10:46 PM
"...researchers who invest time in their students tend to lead more-productive, more-collaborative groups and attract stronger future students than those who do not." "Time spent with the next generation of scientists is an investment."
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Eva Dvorak Tomastikova
Reposted by Eva Dvorak Tomastikova
October 24, 2025 at 3:50 AM
Reposted by Eva Dvorak Tomastikova
🧬✨ It’s official!
EMPSEB31 is coming to Germany, June 2026!
Europe’s friendliest evolution meeting returns, organized by PhD students, for PhD students.
Expect inspiring research, new connections, and a mix of science + fun, the EMPSEB way!
📍Save the date & follow us for updates! Link in Bio 🌍
EMPSEB31 is coming to Germany, June 2026!
Europe’s friendliest evolution meeting returns, organized by PhD students, for PhD students.
Expect inspiring research, new connections, and a mix of science + fun, the EMPSEB way!
📍Save the date & follow us for updates! Link in Bio 🌍
October 23, 2025 at 3:48 PM
🧬✨ It’s official!
EMPSEB31 is coming to Germany, June 2026!
Europe’s friendliest evolution meeting returns, organized by PhD students, for PhD students.
Expect inspiring research, new connections, and a mix of science + fun, the EMPSEB way!
📍Save the date & follow us for updates! Link in Bio 🌍
EMPSEB31 is coming to Germany, June 2026!
Europe’s friendliest evolution meeting returns, organized by PhD students, for PhD students.
Expect inspiring research, new connections, and a mix of science + fun, the EMPSEB way!
📍Save the date & follow us for updates! Link in Bio 🌍
Reposted by Eva Dvorak Tomastikova
Ever noticed that #CRISPR editing results differ between cells? Awesome PhD student Moritz Schlapansky developed "scOUT-seq" to measure single cell transcriptomes + editing. 1.2 million cells, 74 cell types, living 🐭. Cell subtypes differ wildly from bulk average! www.biorxiv.org/content/10.1...
Cell-stereotyped DNA repair outcomes are widespread during genome editing
Genome editing outcomes are governed by DNA repair pathways that vary with cell type and state. We developed scOUT-seq (single-cell Outcomes Using Transcript sequencing), a scalable approach that join...
www.biorxiv.org
October 24, 2025 at 8:44 AM
Ever noticed that #CRISPR editing results differ between cells? Awesome PhD student Moritz Schlapansky developed "scOUT-seq" to measure single cell transcriptomes + editing. 1.2 million cells, 74 cell types, living 🐭. Cell subtypes differ wildly from bulk average! www.biorxiv.org/content/10.1...