The Lambrechts Lab
@lambrechtslab.bsky.social
Research unit @pasteur.fr investigating arbovirus transmission by mosquitoes.
Reposted by The Lambrechts Lab
OUT NOW! - Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes 🍄🧲🦟☠️
By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.
www.nature.com/articles/s41...
By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.
www.nature.com/articles/s41...
Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes - Nature Microbiology
Insects colonized with Metarhizium fungi emit longifolene to lure new hosts for infection to disperse spores. A fungal strain was engineered to emit longifolene to attract and eliminate mosquitoes.
www.nature.com
October 24, 2025 at 11:03 AM
OUT NOW! - Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes 🍄🧲🦟☠️
By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.
www.nature.com/articles/s41...
By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.
www.nature.com/articles/s41...
Reposted by The Lambrechts Lab
A long-held myth about a mosquito evolving in the London Underground has been debunked! 🦟
The insect gained notoriety in the Second World War, when it fed on Londoners seeking shelter in the rail tunnels during the Blitz.
Discover its true origin story.👇
www.nhm.ac.uk/discover/new...
The insect gained notoriety in the Second World War, when it fed on Londoners seeking shelter in the rail tunnels during the Blitz.
Discover its true origin story.👇
www.nhm.ac.uk/discover/new...
Origins of the London Underground mosquito revealed | Natural History Museum
New research reveals that these insects likely evolved in the Mediterranean basin more than 1,000 years ago.
www.nhm.ac.uk
October 24, 2025 at 9:49 AM
A long-held myth about a mosquito evolving in the London Underground has been debunked! 🦟
The insect gained notoriety in the Second World War, when it fed on Londoners seeking shelter in the rail tunnels during the Blitz.
Discover its true origin story.👇
www.nhm.ac.uk/discover/new...
The insect gained notoriety in the Second World War, when it fed on Londoners seeking shelter in the rail tunnels during the Blitz.
Discover its true origin story.👇
www.nhm.ac.uk/discover/new...
Reposted by The Lambrechts Lab
The so-called 'London Underground mosquito' linked to West Nile Virus evolved over 1,000 years ago — not 200 years ago in Europe. 🦟
New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
October 24, 2025 at 9:04 AM
The so-called 'London Underground mosquito' linked to West Nile Virus evolved over 1,000 years ago — not 200 years ago in Europe. 🦟
New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
Current #mosquitoes evolved more recently than previously thought www.nature.com/articles/d41...
Current mosquitoes evolved more recently than previously thought
Genetic analysis reveals that most living genera of mosquitoes emerged around 73 million years ago.
www.nature.com
October 13, 2025 at 6:36 AM
Current #mosquitoes evolved more recently than previously thought www.nature.com/articles/d41...
🚨 New preprint alert! We have developed a targeted amplicon sequencing panel for Aedes aegypti. We believe it is a powerful and cost-effective tool for studying #mosquito #population #genetics. Curious how it matches up to WGS? Check out our preprint to find out! www.biorxiv.org/content/10.1...
A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti
The mosquito Aedes aegypti is the primary vector for several medically significant arboviruses, including dengue, Zika, chikungunya, and yellow fever. Studying the genetic diversity of Ae. aegypti is ...
www.biorxiv.org
October 3, 2025 at 10:41 AM
🚨 New preprint alert! We have developed a targeted amplicon sequencing panel for Aedes aegypti. We believe it is a powerful and cost-effective tool for studying #mosquito #population #genetics. Curious how it matches up to WGS? Check out our preprint to find out! www.biorxiv.org/content/10.1...
Reposted by The Lambrechts Lab
2 job adverts on a NERC project w myself + @darrenobbard.bsky.social on “What determines the virome: ecology and the environment, evolution, or species history?” early 2026 in
@uniexecec.bsky.social
- Postdoc: jobs.exeter.ac.uk/hrpr_webrecr...
- RA: jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
@uniexecec.bsky.social
- Postdoc: jobs.exeter.ac.uk/hrpr_webrecr...
- RA: jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
September 25, 2025 at 3:55 PM
2 job adverts on a NERC project w myself + @darrenobbard.bsky.social on “What determines the virome: ecology and the environment, evolution, or species history?” early 2026 in
@uniexecec.bsky.social
- Postdoc: jobs.exeter.ac.uk/hrpr_webrecr...
- RA: jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
@uniexecec.bsky.social
- Postdoc: jobs.exeter.ac.uk/hrpr_webrecr...
- RA: jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
Reposted by The Lambrechts Lab
A study by researchers at Princeton, @pasteur.fr, and @ucsandiego.bsky.social reveals that Africa’s low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations.
Mosquito Genetics May Explain Why Zika Virus Outbreaks Are Rare in Africa – But Climate Change Could Shift the Balance - High Meadows Environmental Institute
A new study reveals that Africa’s low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations. Research by scientists at the High Meadows Envi...
environment.princeton.edu
September 22, 2025 at 9:15 PM
A study by researchers at Princeton, @pasteur.fr, and @ucsandiego.bsky.social reveals that Africa’s low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations.
Huge thanks to @gonzalezlabbcn.bsky.social for her invaluable contribution as a member of Alexander Bergman's PhD jury and for the stimulating discussions that ensued. It was a great opportunity to chat about #transposons in #mosquitoes and #Drosophila!
Discussing mosquitoes and fruitflies #transposons with @lambrechtslab.bsky.social lab at @pasteur.fr. Great science in a great place. Congrats to the new @sorbonne-universite.fr Doctor Alexander Bergman!
September 25, 2025 at 12:26 PM
Huge thanks to @gonzalezlabbcn.bsky.social for her invaluable contribution as a member of Alexander Bergman's PhD jury and for the stimulating discussions that ensued. It was a great opportunity to chat about #transposons in #mosquitoes and #Drosophila!
WOW! Systematic testing of 2 #Wolbachia strains for their ability to block transmission of 60 genetically diverse #DENV isolates in #mosquitoes shows substantial heterogeneity and suggests potential long-term selection risks in Wolbachia-based control interventions.
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Heterogeneity in inhibition of genetically diverse dengue virus strains by Wolbachia
The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...
www.biorxiv.org
September 20, 2025 at 10:47 AM
WOW! Systematic testing of 2 #Wolbachia strains for their ability to block transmission of 60 genetically diverse #DENV isolates in #mosquitoes shows substantial heterogeneity and suggests potential long-term selection risks in Wolbachia-based control interventions.
Reposted by The Lambrechts Lab
www.nhm.ac.uk/discover/new...
Mosquitoes that have been in the collection for nearly a hundred years are helping us in dealing with an even older but also current problem - malaria
@sangerinstitute.bsky.social @nhm-london.bsky.social
Mosquitoes that have been in the collection for nearly a hundred years are helping us in dealing with an even older but also current problem - malaria
@sangerinstitute.bsky.social @nhm-london.bsky.social
Genetic study of malaria-carrying mosquitoes tracks evolution of insecticide resistance | Natural History Museum
It crucially also reveals promising genetic targets for potential control.
www.nhm.ac.uk
September 19, 2025 at 11:53 AM
www.nhm.ac.uk/discover/new...
Mosquitoes that have been in the collection for nearly a hundred years are helping us in dealing with an even older but also current problem - malaria
@sangerinstitute.bsky.social @nhm-london.bsky.social
Mosquitoes that have been in the collection for nearly a hundred years are helping us in dealing with an even older but also current problem - malaria
@sangerinstitute.bsky.social @nhm-london.bsky.social
How the yellow fever mosquito conquered the world | Science | AAAS www.science.org/content/arti...
How the yellow fever mosquito conquered the world
Aedes aegypti further adapted to life around humans when it arrived in the Americas, study of hundreds of mosquito genomes reveals
www.science.org
September 19, 2025 at 8:00 AM
How the yellow fever mosquito conquered the world | Science | AAAS www.science.org/content/arti...
Genomic clues into the spread of deadly mosquitoes | Science www.science.org/doi/10.1126/...
Genomic clues into the spread of deadly mosquitoes
Ancient and more recent human interactions shape mosquito vector evolution
www.science.org
September 19, 2025 at 7:00 AM
Genomic clues into the spread of deadly mosquitoes | Science www.science.org/doi/10.1126/...
Reposted by The Lambrechts Lab
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk | Science www.science.org/doi/10.1126/....
A seminal paper of great interest to all. Great work and congratulations to the team!
A seminal paper of great interest to all. Great work and congratulations to the team!
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk
The emergence and global expansion of Aedes aegypti puts more than half of all humans at risk of arbovirus infection, but the origin of this mosquito and the impact of contemporary gene flow on arbovi...
www.science.org
September 18, 2025 at 9:29 PM
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk | Science www.science.org/doi/10.1126/....
A seminal paper of great interest to all. Great work and congratulations to the team!
A seminal paper of great interest to all. Great work and congratulations to the team!
Reposted by The Lambrechts Lab
Striking and frightening 😒 "They found multiple instances of insecticide-resistance variants in this malaria vector, although most of these weren’t shared with museum specimens collected as recently as 1967, suggesting rapid emergence"
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Genomic diversity of the African malaria vector Anopheles funestus
Anopheles funestus s.s. is a major human malaria vector across Africa. To study its evolution, especially under vector control pressure, we sequenced 656 modern specimens (collected 2014 to 2018) and ...
www.science.org
September 19, 2025 at 5:23 AM
Striking and frightening 😒 "They found multiple instances of insecticide-resistance variants in this malaria vector, although most of these weren’t shared with museum specimens collected as recently as 1967, suggesting rapid emergence"
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
ScienceAdviser: Mosquitoes seem to love hedonists | Science | AAAS www.science.org/content/arti...
ScienceAdviser: Mosquitoes seem to love hedonists
Today in Science and science: How corpse flowers make a big stink, a rocky start for the ocean, and more
www.science.org
September 19, 2025 at 6:50 AM
ScienceAdviser: Mosquitoes seem to love hedonists | Science | AAAS www.science.org/content/arti...
Reposted by The Lambrechts Lab
Chikungunya : forte hausse des cas autochtones en métropole, Santé publique France appelle à la vigilance face aux moustiques tigres
Chikungunya : forte hausse des cas autochtones en métropole, Santé publique France appelle à la vigilance face aux moustiques tigres
L’implantation du moustique tigre dans 81 départements métropolitains inquiète les autorités, qui redoutent une propagation accrue du chikungunya et d’autres maladies vectorielles cet automne.
www.lemonde.fr
September 17, 2025 at 10:00 PM
Chikungunya : forte hausse des cas autochtones en métropole, Santé publique France appelle à la vigilance face aux moustiques tigres
Reposted by The Lambrechts Lab
Brazil hopes to turn the tide of dengue with a home-grown vaccine and an army of mosquitoes
go.nature.com/41VWT1V
go.nature.com/41VWT1V
How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus
Outbreaks of dengue are killing thousands of people in South America each year and getting worse. Brazil hopes to turn the tide with a home-grown vaccine and an army of mosquitoes infected with Wolbachia bacteria.
go.nature.com
September 16, 2025 at 12:20 PM
Brazil hopes to turn the tide of dengue with a home-grown vaccine and an army of mosquitoes
go.nature.com/41VWT1V
go.nature.com/41VWT1V
Mosquito-borne viruses surge in a warming Europe | Science | AAAS www.science.org/content/arti...
Mosquito-borne viruses surge in a warming Europe
Chikungunya cases break records in France; West Nile virus appears near Rome
www.science.org
September 12, 2025 at 6:30 AM
Mosquito-borne viruses surge in a warming Europe | Science | AAAS www.science.org/content/arti...
Reposted by The Lambrechts Lab
@elodiecouderc.bsky.social is on 🔥 this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at @cp-trendsmicrobiol.bsky.social. Check it ou here: www.cell.com/trends/micro...
September 1, 2025 at 1:26 PM
@elodiecouderc.bsky.social is on 🔥 this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at @cp-trendsmicrobiol.bsky.social. Check it ou here: www.cell.com/trends/micro...
Reposted by The Lambrechts Lab
Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...
September 8, 2025 at 12:58 PM
Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...
Reposted by The Lambrechts Lab
New #review out 🚨 for mosquito enthusiasts 🦟 !
Have you ever questioned the approach you routinely use to investigate #mosquito-virus #interactions? ⬇️
www.sciencedirect.com/science/arti...
Have you ever questioned the approach you routinely use to investigate #mosquito-virus #interactions? ⬇️
www.sciencedirect.com/science/arti...
August 29, 2025 at 2:27 PM
New #review out 🚨 for mosquito enthusiasts 🦟 !
Have you ever questioned the approach you routinely use to investigate #mosquito-virus #interactions? ⬇️
www.sciencedirect.com/science/arti...
Have you ever questioned the approach you routinely use to investigate #mosquito-virus #interactions? ⬇️
www.sciencedirect.com/science/arti...
Does #dengue virus hijack #mosquitoes' brain? Study led by Felix Hol @pasteur.fr discovered that infected mosquitoes take smaller blood meals. As a result, they bite more often, and potentially infect infect more people.
(video in French with English subtitles available)
youtu.be/2u_qckfAQa4?...
(video in French with English subtitles available)
youtu.be/2u_qckfAQa4?...
La dengue aux commandes
YouTube video by Institut Pasteur
youtu.be
August 28, 2025 at 11:42 AM
Does #dengue virus hijack #mosquitoes' brain? Study led by Felix Hol @pasteur.fr discovered that infected mosquitoes take smaller blood meals. As a result, they bite more often, and potentially infect infect more people.
(video in French with English subtitles available)
youtu.be/2u_qckfAQa4?...
(video in French with English subtitles available)
youtu.be/2u_qckfAQa4?...
Reposted by The Lambrechts Lab
Blood, sweat, and beers: investigating mosquito biting preferences amidst noise and intoxication in a cross-sectional cohort study at a large music festival https://www.biorxiv.org/content/10.1101/2025.08.21.671470v1
August 26, 2025 at 1:45 PM
Blood, sweat, and beers: investigating mosquito biting preferences amidst noise and intoxication in a cross-sectional cohort study at a large music festival https://www.biorxiv.org/content/10.1101/2025.08.21.671470v1
Reposted by The Lambrechts Lab
🚀 Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes - BMC Biology
Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses foc...
bmcbiol.biomedcentral.com
August 27, 2025 at 12:10 PM
🚀 Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
🦟🦠 Check out our latest article in @natcomms.nature.com on the genetic basis of #dengue virus susceptibility in #mosquitoes! Collaborative work brillantly led by @merklinglab.bsky.social and @elodiecouderc.bsky.social @pasteur.fr and primarily supported by @agencerecherche.bsky.social rdcu.be/eBbg7
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Nature Communications - Genetic factors affecting Aedes aegypti susceptibility to dengue virus infection aren’t well studied. Here the authors show that a cytochrome P450 gene, typically...
rdcu.be
August 18, 2025 at 10:08 AM
🦟🦠 Check out our latest article in @natcomms.nature.com on the genetic basis of #dengue virus susceptibility in #mosquitoes! Collaborative work brillantly led by @merklinglab.bsky.social and @elodiecouderc.bsky.social @pasteur.fr and primarily supported by @agencerecherche.bsky.social rdcu.be/eBbg7