Sarah Merkling
@merklinglab.bsky.social
We are all about mosquitoes, viruses and single cells!
Insect Infection and Immunity - Merkling Lab
@CNRS.fr @Pasteur.fr @ERC.europa.eu
#newPI #DiversityEquityInclusion #ally 🏳️🌈🏳️⚧️
https://aedes-cell-atlas.pasteur.cloud/
Insect Infection and Immunity - Merkling Lab
@CNRS.fr @Pasteur.fr @ERC.europa.eu
#newPI #DiversityEquityInclusion #ally 🏳️🌈🏳️⚧️
https://aedes-cell-atlas.pasteur.cloud/
Pinned
Sarah Merkling
@merklinglab.bsky.social
· Aug 18
🦟🦠 Check out our latest article in @natcomms.nature.com on the genetic basis of #dengue virus susceptibility in #mosquitoes! Collaborative work brillantly led by @merklinglab.bsky.social and @elodiecouderc.bsky.social @pasteur.fr and primarily supported by @agencerecherche.bsky.social rdcu.be/eBbg7
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Nature Communications - Genetic factors affecting Aedes aegypti susceptibility to dengue virus infection aren’t well studied. Here the authors show that a cytochrome P450 gene, typically...
rdcu.be
Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)
Reposted by Sarah Merkling
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
September 23, 2025 at 2:22 PM
👩🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !
Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...
September 8, 2025 at 12:58 PM
Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...
@elodiecouderc.bsky.social is on 🔥 this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at @cp-trendsmicrobiol.bsky.social. Check it ou here: www.cell.com/trends/micro...
September 1, 2025 at 1:26 PM
@elodiecouderc.bsky.social is on 🔥 this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at @cp-trendsmicrobiol.bsky.social. Check it ou here: www.cell.com/trends/micro...
Reposted by Sarah Merkling
RIP Margaret Rossiter, who coined the phrase the Matilda Effect (amongst many others), a phenomenon too many women will have seen first hand
Good to see the New York Times has a lengthy obituary for Margaret Rossiter
Margaret W. Rossiter, 81, Dies; Wrote Women Scientists Into History
www.nytimes.com
August 30, 2025 at 7:49 PM
RIP Margaret Rossiter, who coined the phrase the Matilda Effect (amongst many others), a phenomenon too many women will have seen first hand
👏So proud to share @elodiecouderc.bsky.social work on the role of Vago-like genes in mosquito immunity. Please read her thread to get a sneak-peek of our work and find the full study here: rdcu.be/eCPmG
August 28, 2025 at 7:42 AM
👏So proud to share @elodiecouderc.bsky.social work on the role of Vago-like genes in mosquito immunity. Please read her thread to get a sneak-peek of our work and find the full study here: rdcu.be/eCPmG
Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)
🦟🦠 Check out our latest article in @natcomms.nature.com on the genetic basis of #dengue virus susceptibility in #mosquitoes! Collaborative work brillantly led by @merklinglab.bsky.social and @elodiecouderc.bsky.social @pasteur.fr and primarily supported by @agencerecherche.bsky.social rdcu.be/eBbg7
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Nature Communications - Genetic factors affecting Aedes aegypti susceptibility to dengue virus infection aren’t well studied. Here the authors show that a cytochrome P450 gene, typically...
rdcu.be
August 18, 2025 at 12:05 PM
Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)
Reposted by Sarah Merkling
David Hall & @vectorimmunity.bsky.social highlight @merklinglab.bsky.social & colleagues’ Cell Genomics article on #mosquito cellular responses in #midgut & #fatbody after #bloodfeeding. #Aedes #aegypti #scRNAseq #Metabolomics @iastateresearch.bsky.social
authors.elsevier.com/a/1lbEr5Eb1x...
authors.elsevier.com/a/1lbEr5Eb1x...
August 13, 2025 at 11:49 AM
David Hall & @vectorimmunity.bsky.social highlight @merklinglab.bsky.social & colleagues’ Cell Genomics article on #mosquito cellular responses in #midgut & #fatbody after #bloodfeeding. #Aedes #aegypti #scRNAseq #Metabolomics @iastateresearch.bsky.social
authors.elsevier.com/a/1lbEr5Eb1x...
authors.elsevier.com/a/1lbEr5Eb1x...
Reposted by Sarah Merkling
July 14, 2025 at 11:41 PM
Reposted by Sarah Merkling
🌈 United for diversity in science 🌈
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social
👩🔬 Because diverse labs make better science.
#DiversityInScience
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social
👩🔬 Because diverse labs make better science.
#DiversityInScience
June 30, 2025 at 12:36 PM
🌈 United for diversity in science 🌈
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social
👩🔬 Because diverse labs make better science.
#DiversityInScience
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social
👩🔬 Because diverse labs make better science.
#DiversityInScience
🎉 Our study is now published in Cell Genomics ! Thank to our reviewers for helping us further improve our work, and congratulations to @tompvial.bsky.social who lead this project and the entire team that made it possible ! www.cell.com/cell-genomic...
June 26, 2025 at 10:20 AM
🎉 Our study is now published in Cell Genomics ! Thank to our reviewers for helping us further improve our work, and congratulations to @tompvial.bsky.social who lead this project and the entire team that made it possible ! www.cell.com/cell-genomic...
Awesome post-doc position available within the @maringerlab.bsky.social ! I can highly recommend applying to @pirbrightinst.bsky.social - Kevin and Trevor are wonderful PI's to be working with !
We have a postdoc position available in which we’re using flavivirus replication/molecular biology to make refractory mosquitoes - in collaboration with the Trevor Sweeney lab at @pirbrightinst.bsky.social. Check out the advert on LinkedIn and apply by 12/6.
www.linkedin.com/jobs/view/42...
www.linkedin.com/jobs/view/42...
The Pirbright Institute hiring Postdoctoral Researcher in Woking, England, United Kingdom | LinkedIn
Posted 1:09:44 PM. Postdoctoral Researcher – (24P-73)The Pirbright Institute Salary: £38,5000 to 40,000 per annum36…See this and similar jobs on LinkedIn.
www.linkedin.com
June 4, 2025 at 12:23 PM
Awesome post-doc position available within the @maringerlab.bsky.social ! I can highly recommend applying to @pirbrightinst.bsky.social - Kevin and Trevor are wonderful PI's to be working with !
Reposted by Sarah Merkling
Planning to apply for #research #funding from the ERC?
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
europa.eu
June 2, 2025 at 10:02 AM
Planning to apply for #research #funding from the ERC?
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
From the next application rounds, expect changes to the:
• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)
More 👇 europa.eu/!RPHWvv
Had the pleasure of listening to @ardemp.bskyverified.social’s lecture yesterday at @pasteur.fr - and seeing a live demonstration of the Piezo tattoo !
May 29, 2025 at 7:46 AM
Had the pleasure of listening to @ardemp.bskyverified.social’s lecture yesterday at @pasteur.fr - and seeing a live demonstration of the Piezo tattoo !
Reposted by Sarah Merkling
Wrapped up a 4 seminar Tour de 🇫🇷 with stops in Lyon, Strasbourg, and Paris (IBPS, Pasteur). Had a blast with fellow scientists across the pond, lots of convo about the current US landscape. You might recognize Jean-Marie Lehn, Jean-Pierre Changeux, and Christine Petit. Also: white asparagus season!
May 28, 2025 at 9:11 PM
Wrapped up a 4 seminar Tour de 🇫🇷 with stops in Lyon, Strasbourg, and Paris (IBPS, Pasteur). Had a blast with fellow scientists across the pond, lots of convo about the current US landscape. You might recognize Jean-Marie Lehn, Jean-Pierre Changeux, and Christine Petit. Also: white asparagus season!
Reposted by Sarah Merkling
Choose Science. Choose Europe.
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September → europa.eu/!fBTMgF
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September → europa.eu/!fBTMgF
May 8, 2025 at 10:12 AM
Choose Science. Choose Europe.
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September → europa.eu/!fBTMgF
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September → europa.eu/!fBTMgF
Had a wonderful time at the #EMBLChromatin meeting in Heidelberg last week with @sumeyye-ozhan.bsky.social who was sponsored by a @pasteur.fr - @events.embl.org travel award ! @sebbaumgarten.bsky.social ;)
May 19, 2025 at 6:48 PM
Had a wonderful time at the #EMBLChromatin meeting in Heidelberg last week with @sumeyye-ozhan.bsky.social who was sponsored by a @pasteur.fr - @events.embl.org travel award ! @sebbaumgarten.bsky.social ;)
Reposted by Sarah Merkling
@sebbontempsgallo.bsky.social , Chercheur @cnrs-hautsdefrance.bsky.social @cnrsbiologie.bsky.social
Maladie de #Lyme : comment s’en protéger ?
Maladie de #Lyme : comment s’en protéger ?
Maladie de Lyme : comment s’en protéger ? - Sébastien Bontemps Gallo - 10' de prév'
YouTube video by Pasteur Lille
www.youtube.com
May 18, 2025 at 10:31 AM
@sebbontempsgallo.bsky.social , Chercheur @cnrs-hautsdefrance.bsky.social @cnrsbiologie.bsky.social
Maladie de #Lyme : comment s’en protéger ?
Maladie de #Lyme : comment s’en protéger ?
Reposted by Sarah Merkling
Our paper is now published in its final form: rdcu.be/elV6u @biomedcentral.bsky.social @salehlabparis.bsky.social @merklinglab.bsky.social @pasteur.fr
May 15, 2025 at 6:57 AM
Our paper is now published in its final form: rdcu.be/elV6u @biomedcentral.bsky.social @salehlabparis.bsky.social @merklinglab.bsky.social @pasteur.fr
Reposted by Sarah Merkling
Our department (Dev & Stem Cells) @igbmc.bsky.social has an open call for group leaders (all areas of cell biology considered!). Check out website for synergies! Please help spread the word (incl to postdocs in the US!! Strasbourg isn't a bad place to live 😜) @cnrsbiologie.bsky.social @inserm.fr
March 19, 2025 at 5:45 PM
Our department (Dev & Stem Cells) @igbmc.bsky.social has an open call for group leaders (all areas of cell biology considered!). Check out website for synergies! Please help spread the word (incl to postdocs in the US!! Strasbourg isn't a bad place to live 😜) @cnrsbiologie.bsky.social @inserm.fr
Reposted by Sarah Merkling
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
March 22, 2025 at 11:39 PM
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
Reposted by Sarah Merkling
Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome?
Funding call with deadline 15 June, decisions in July.
www.embl.org/about/info/s...
Funding call with deadline 15 June, decisions in July.
www.embl.org/about/info/s...
March 19, 2025 at 5:31 PM
Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome?
Funding call with deadline 15 June, decisions in July.
www.embl.org/about/info/s...
Funding call with deadline 15 June, decisions in July.
www.embl.org/about/info/s...
Absolutely stunning work by @steinaerts.bsky.social and @frankschoonbeek.bsky.social 🤩
Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
March 6, 2025 at 6:58 PM
Absolutely stunning work by @steinaerts.bsky.social and @frankschoonbeek.bsky.social 🤩
Reposted by Sarah Merkling
A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.”
Absurd we still need to go through this
🧪👩🔬
Absurd we still need to go through this
🧪👩🔬
March 6, 2025 at 4:40 PM
A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.”
Absurd we still need to go through this
🧪👩🔬
Absurd we still need to go through this
🧪👩🔬
Happy to share our work exploring the genetic basis of dengue susceptibility in Aedes aegypti and revealing the antiviral role of a cytochrome P450. www.biorxiv.org/content/10.1...
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 variants
The mosquito Aedes aegypti is the primary vector for dengue virus (DENV), which infects millions of people annually. Variability in DENV susceptibility among wild Ae. aegypti populations is governed b...
www.biorxiv.org
February 28, 2025 at 12:17 PM
Happy to share our work exploring the genetic basis of dengue susceptibility in Aedes aegypti and revealing the antiviral role of a cytochrome P450. www.biorxiv.org/content/10.1...
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️