Kiran R. Patil
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kiranrpatil.bsky.social
Kiran R. Patil
@kiranrpatil.bsky.social
Professor of Molecular Systems Biology, University of Cambridge
Reposted by Kiran R. Patil
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Another fantastic study from @lisamaierlab.bsky.social showing how non-antibiotics impact gut ecosytem. Congratulations @ghammeranne.bsky.social et al.!
July 17, 2025 at 12:23 PM
Reposted by Kiran R. Patil
@skamrad.bsky.social @kiranrpatil.bsky.social show xenobiotics impact growth of gut bacteria and their metabolic homeostasis by affecting amine metabolism ➡️ www.embopress.org/doi/full/10....
July 3, 2025 at 12:44 PM
Reposted by Kiran R. Patil
Excited to share some key details on our latest research in @natmicrobiol.nature.com reporting intra-cellular accumulation of #PFAS (aka forever chemicals) by certain human gut bacteria. #microsky #mevosky #microbiomesky
www.nature.com/articles/s41...
July 2, 2025 at 2:57 PM
Reposted by Kiran R. Patil
#NewResearch

🚨Out now!

Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion. @kiranrpatil.bsky.social

#MicroSky #MicrobiomeSky 🦠

www.nature.com/articles/s41...
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
www.nature.com
July 1, 2025 at 3:18 PM
Reposted by Kiran R. Patil
Beautiful work from my friend @kiranrpatil.bsky.social . Gut bacteria can accumulate Forever chemicals and help us get rid of them! Happy we could contribute! www.nature.com/articles/s41...
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
www.nature.com
July 1, 2025 at 11:25 AM
Reposted by Kiran R. Patil
Gut bacteria to the rescue! 🦠✨
They can shield us from harmful chemicals—and the latest study from Kiran Patil's lab (@kiranrpatil.bsky.social)
uncovers how. We’re proud to have contributed to this exciting work!
#Microbiome #Detox
www.nature.com/articles/s41...
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
www.nature.com
July 1, 2025 at 10:03 AM
Reposted by Kiran R. Patil
Researchers in the Patil Lab have discovered that certain species of gut bacteria can absorb PFAS. Boosting these species in our gut microbiome could be a new way to protect us from the harmful effects of PFAS.

Read more here: buff.ly/4FsVFsS

@kiranrpatil.bsky.social @indraroux.bsky.social
July 1, 2025 at 9:02 AM
Latest study from the lab is online today (and another will be out tomorrow, stay tuned:)). We profiled effect of >1700 chemicals (drugs, pesticides,...) on secretion of amines (involved in gut-brain and gut-immune axis. ) by human gut bacteria. Brilliant work by @skamrad.bsky.social and Tara Davis
Stephan Kamrad and Tara Davis in the Patil lab at the MRC Toxicology Unit have identified that some drugs and environmental contaminants alter gut bacterial amine metabolism.

Find out more here: buff.ly/5akzsgs
@kiranrpatil.bsky.social @skamrad.bsky.social
June 30, 2025 at 6:44 PM
Reposted by Kiran R. Patil
Check out our new preprint!
We systematically map proteomic and metabolomic interactions between >100 pairs of gut bacteria, detecting metabolic interactions and functionally-related clusters of proteins.

www.biorxiv.org/content/10.1...

@kiranrpatil.bsky.social
Interspecies interactions drive bacterial proteome reorganisation and emergent metabolism
Species in microbial communities must respond to the presence of others to stave off resource competition or to capitalise on new resources that may become available due to additional metabolic activi...
www.biorxiv.org
May 15, 2025 at 10:13 AM
Reposted by Kiran R. Patil
📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
April 16, 2025 at 5:40 PM
Sweeteners are so common in food and drinks. New work expanding our knowledge base of sweetener-bacteria interactions 👇🏽. Kudos to @sonjablasche.bsky.social @indraroux.bsky.social and others from our lab
April 5, 2025 at 7:47 AM
Kudos to Ghada @kostchristian.bsky.social team and @metagenomez.bsky.social et al. for this mammoth effort! An important step forward towards understanding natural microbial communities and determinants of their fascinating diversity.
January 31, 2025 at 9:18 AM
Congratulations to talented @naomiirisvdberg.bsky.social for successfully passing her PhD exam! Very proud of the latest PhD graduate from my lab and the entire team! 🙌🎉🍾
January 27, 2025 at 11:31 AM
Reposted by Kiran R. Patil
Looking for a postdoctoral fellowship? Interested in tackling real-world challenges? Then check EMBL's EIPOD-LinC fellowships.

👉 Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.

✍️ More information: www.embl.org/about/info/p...

🧪 #careers
January 13, 2025 at 3:51 PM
“Manufactured Chemicals and Children’s Health..” – an excellent evidence-based case in N Eng J Med. Despite overwhelming epidemiological evidence (Note: randomised clinical trials are obviously unethical), less than 20% chemicals are tested for toxicity.

www.nejm.org/doi/full/10....
January 13, 2025 at 9:19 AM
Reposted by Kiran R. Patil
Interested in the ecological dynamics of Enterobacteriaceae across populations? Check out our new study 🧬
January 10, 2025 at 10:50 AM
Reposted by Kiran R. Patil
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...
December 16, 2024 at 8:43 AM