Our study provides a new window into understanding the toxicokinetics of PFAS and a step towards development of scalable biotechnological solutions for PFAS removal. Thanks to fantastic team members, especially first-author Anna Lindell, and all collaborators for making this possible.

Last but not least, we show that bioaccumulation happens within mouse gut environment and high-accumulating bacterial communities accelerate PFAS clearance through feces. Thanks to @lisamaierlab.bsky.social

PFAS was thought to interact only passively with cell membranes (and thus get stuck there). Our genetic analysis shows involvement of efflux pumps and thus implies active transport. We should not repeat the mistake of assuming passive interactions - Biology is complex and full of surprises!

This feat is achieved because these molecules aggregate in dense clumps, leaving the cellular machinery unaffected. These clumps are visible at single cell resolution with cryo-FIB-SIMS. @tbharat-lab.bsky.social

The study is the first report of PFAS bioaccumulation by gut bacteria. Through extensive screening, we discovered bioaccumulation by a group of prevalent human gut bacteria and across a wide concentration range (as low as 0.34 nM).

Excited to share some key details on our latest research in @natmicrobiol.nature.com reporting intra-cellular accumulation of #PFAS (aka forever chemicals) by certain human gut bacteria. #microsky #mevosky #microbiomesky
www.nature.com/articles/s41...

thank you @tbharat-lab.bsky.social lab! So cool to see the PFAS inside single cells with your technology!

Congratulations to talented @naomiirisvdberg.bsky.social for successfully passing her PhD exam! Very proud of the latest PhD graduate from my lab and the entire team! 🙌🎉🍾

“Manufactured Chemicals and Children’s Health..” – an excellent evidence-based case in N Eng J Med. Despite overwhelming epidemiological evidence (Note: randomised clinical trials are obviously unethical), less than 20% chemicals are tested for toxicity.

www.nejm.org/doi/full/10....