Jose Jimenez
@jjimenez.bsky.social
Reader in Synthetic Biology at Imperial College London #synbio and evolution for health, the environment and the circular economy josejimenezlab.com
Pinned
Jose Jimenez
@jjimenez.bsky.social
· Oct 3
Directed evolution and characterisation of light harvesting complexes with altered energy transfer dynamics in purple non-sulfur bacteria
Purple non-sulfur bacteria (PNSB) are metabolically versatile microorganisms that inhabit diverse environments taking advantage of a remarkably efficient photosynthetic machinery. In this work, we des...
www.biorxiv.org
Preprint alert!! Delighted to share Eve Nery's work exploring the evolutionary landscape of light-harvesting complexes. She found a new variant shifted to the red that allows purple bacteria to grow faster under high intensity light www.biorxiv.org/content/10.1...
Reposted by Jose Jimenez
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
November 24, 2025 at 1:15 PM
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
Just found this definition in the gov.uk webpage that thought might be useful for some. Btw, someone between 14 and 18 years old is sometimes called a Young Person, but is still legally a child.
November 14, 2025 at 8:52 PM
Just found this definition in the gov.uk webpage that thought might be useful for some. Btw, someone between 14 and 18 years old is sometimes called a Young Person, but is still legally a child.
The scariest thing I have seen this Halloween
October 31, 2025 at 7:05 PM
The scariest thing I have seen this Halloween
Reposted by Jose Jimenez
The Wallace Lab is expanding in 2026, with five new Postdoctoral Research Associate positions now open. If you're passionate about engineering biology for sustainability, we'd love to hear from you! 🧬 ♻️
Deadline: 12th November 2025, details below ⬇️
Deadline: 12th November 2025, details below ⬇️
October 29, 2025 at 12:34 PM
The Wallace Lab is expanding in 2026, with five new Postdoctoral Research Associate positions now open. If you're passionate about engineering biology for sustainability, we'd love to hear from you! 🧬 ♻️
Deadline: 12th November 2025, details below ⬇️
Deadline: 12th November 2025, details below ⬇️
Reposted by Jose Jimenez
1 week left to apply for a postdoctoral position in my group to lead the experimental component of a 5 year BBSRC project on synthetic microbial communities
www.ucl.ac.uk/work-at-ucl/...
www.ucl.ac.uk/work-at-ucl/...
October 20, 2025 at 9:49 AM
1 week left to apply for a postdoctoral position in my group to lead the experimental component of a 5 year BBSRC project on synthetic microbial communities
www.ucl.ac.uk/work-at-ucl/...
www.ucl.ac.uk/work-at-ucl/...
Reposted by Jose Jimenez
Oct. 23, 6pm at UCL 🥳! Excited for:
🧬 Dirk Benzinger (Briscoe Lab)
Dissecting and engineering cellular signal processing with synthetic biology and optogenetics
🌍 Brooke Wain (Jimenez Lab)
Biocatalytic recycling of plastic: industrial viability and limitations
events.humanitix.com/london-synbi...
🧬 Dirk Benzinger (Briscoe Lab)
Dissecting and engineering cellular signal processing with synthetic biology and optogenetics
🌍 Brooke Wain (Jimenez Lab)
Biocatalytic recycling of plastic: industrial viability and limitations
events.humanitix.com/london-synbi...
London SynBio Network 11
London SynBio afterwork talks and networking event on Thursday 23rd of September
events.humanitix.com
October 16, 2025 at 11:05 AM
Oct. 23, 6pm at UCL 🥳! Excited for:
🧬 Dirk Benzinger (Briscoe Lab)
Dissecting and engineering cellular signal processing with synthetic biology and optogenetics
🌍 Brooke Wain (Jimenez Lab)
Biocatalytic recycling of plastic: industrial viability and limitations
events.humanitix.com/london-synbi...
🧬 Dirk Benzinger (Briscoe Lab)
Dissecting and engineering cellular signal processing with synthetic biology and optogenetics
🌍 Brooke Wain (Jimenez Lab)
Biocatalytic recycling of plastic: industrial viability and limitations
events.humanitix.com/london-synbi...
This is how Castilla La Mancha will conquer the world: blending tradition and empathy. I'd recommend all world leaders to complete a couple of grape harvests (vendimia) to develop thoughtful leadership. Great mix of cardio and strength exercise too!
www.theguardian.com/world/2025/o...
www.theguardian.com/world/2025/o...
‘It’s a question of humanity’: how a small Spanish town made headlines over its immigration stance
Mayor explains why Villamalea unanimously backed call to regularise undocumented migrants – across party lines
www.theguardian.com
October 11, 2025 at 2:33 PM
This is how Castilla La Mancha will conquer the world: blending tradition and empathy. I'd recommend all world leaders to complete a couple of grape harvests (vendimia) to develop thoughtful leadership. Great mix of cardio and strength exercise too!
www.theguardian.com/world/2025/o...
www.theguardian.com/world/2025/o...
New preprint this time through a fantastic collaboration with @jorgebarriuso.bsky.social and team. We have discovered the genetic basis behind the remarkable ability of Pseudomonas putida JM37 to use the PET #plastic monomer ethylene glycol as a growth substrate! www.biorxiv.org/content/10.1...
Pseudomonas putida JM37 as a novel bacterial chassis for ethylene glycol upcycling
Ethylene glycol (EG), one of the main monomers of polyethylene terephthalate (PET), is an attractive target for microbial upcycling. Despite this interest, there is a limited number of described organ...
www.biorxiv.org
October 8, 2025 at 8:48 AM
New preprint this time through a fantastic collaboration with @jorgebarriuso.bsky.social and team. We have discovered the genetic basis behind the remarkable ability of Pseudomonas putida JM37 to use the PET #plastic monomer ethylene glycol as a growth substrate! www.biorxiv.org/content/10.1...
Reposted by Jose Jimenez
Metabolic interplay drives population cycles in a cross-feeding microbial community
@natcomms.nature.com from @oventurelli2.bsky.social
www.nature.com/articles/s41...
@natcomms.nature.com from @oventurelli2.bsky.social
www.nature.com/articles/s41...
Metabolic interplay drives population cycles in a cross-feeding microbial community - Nature Communications
Here the authors leverage a crossfeeding, engineered microbial community to demonstrate that strain abundance cycles are robust across environmental conditions. They pair this with a nonlinear dynamic model to elucidate population cycles.
www.nature.com
October 7, 2025 at 7:09 PM
Metabolic interplay drives population cycles in a cross-feeding microbial community
@natcomms.nature.com from @oventurelli2.bsky.social
www.nature.com/articles/s41...
@natcomms.nature.com from @oventurelli2.bsky.social
www.nature.com/articles/s41...
Reposted by Jose Jimenez
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Reposted by Jose Jimenez
Mapping the evolution of computationally designed protein binders [new]
Evolve comp. mini-protein binders *in vivo*. Maps seq-affinity.
Evolve comp. mini-protein binders *in vivo*. Maps seq-affinity.
October 6, 2025 at 3:15 AM
Mapping the evolution of computationally designed protein binders [new]
Evolve comp. mini-protein binders *in vivo*. Maps seq-affinity.
Evolve comp. mini-protein binders *in vivo*. Maps seq-affinity.
Reposted by Jose Jimenez
PhD positions available in our group! Please share! www.findaphd.com/phds/project...
PhD Scholarship project: Engineering biology approaches to mammalian cells at Imperial College London on FindAPhD.com
PhD Project - PhD Scholarship project: Engineering biology approaches to mammalian cells at Imperial College London, listed on FindAPhD.com
www.findaphd.com
October 6, 2025 at 7:31 AM
PhD positions available in our group! Please share! www.findaphd.com/phds/project...
Reposted by Jose Jimenez
Microbial stem cells support productivity in dedicated factory cells in an asymmetrically dividing E. coli system
doi.org/10.1101/2025...
doi.org/10.1101/2025...
October 6, 2025 at 7:03 AM
Microbial stem cells support productivity in dedicated factory cells in an asymmetrically dividing E. coli system
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Preprint alert!! Delighted to share Eve Nery's work exploring the evolutionary landscape of light-harvesting complexes. She found a new variant shifted to the red that allows purple bacteria to grow faster under high intensity light www.biorxiv.org/content/10.1...
Directed evolution and characterisation of light harvesting complexes with altered energy transfer dynamics in purple non-sulfur bacteria
Purple non-sulfur bacteria (PNSB) are metabolically versatile microorganisms that inhabit diverse environments taking advantage of a remarkably efficient photosynthetic machinery. In this work, we des...
www.biorxiv.org
October 3, 2025 at 7:07 AM
Preprint alert!! Delighted to share Eve Nery's work exploring the evolutionary landscape of light-harvesting complexes. She found a new variant shifted to the red that allows purple bacteria to grow faster under high intensity light www.biorxiv.org/content/10.1...
Reposted by Jose Jimenez
Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria - Nature Communications
Engineered gene circuits often degrade over time due to mutation and selection. Here the authors use a host-aware modelling framework to develop genetic controllers to sustain synthetic gene expression. They identify a range of design trade-offs in production, robustness and long-term performance.
doi.org
October 2, 2025 at 7:12 AM
Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Jose Jimenez
I am looking for a motivated #Postdoctoral #Researcher to join my group at Imperial @imperialcollegeldn.bsky.social @imperiallifesci.bsky.social. The project focuses on #Antimicrobial #Materials & #Biomimetic #Interfaces
Please repost!
@imperialsci.bsky.social
www.imperial.ac.uk/jobs/search-...
Please repost!
@imperialsci.bsky.social
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
September 19, 2025 at 10:09 AM
I am looking for a motivated #Postdoctoral #Researcher to join my group at Imperial @imperialcollegeldn.bsky.social @imperiallifesci.bsky.social. The project focuses on #Antimicrobial #Materials & #Biomimetic #Interfaces
Please repost!
@imperialsci.bsky.social
www.imperial.ac.uk/jobs/search-...
Please repost!
@imperialsci.bsky.social
www.imperial.ac.uk/jobs/search-...
Reposted by Jose Jimenez
A bit of an awkward request but hoping that someone can help. We are desperately looking for a vial of CHO-S cells that we could use. Ideally in the London area. Thanks!
September 11, 2025 at 3:20 PM
A bit of an awkward request but hoping that someone can help. We are desperately looking for a vial of CHO-S cells that we could use. Ideally in the London area. Thanks!
Ok, to be precise (thanks @marcsdionne.bsky.social), they are considering implementing triage
BBSRC to implement triage of proposals pre-panel and rolling deadlines to reduce assessment burden. Interesting times ahead!
September 10, 2025 at 11:47 AM
Ok, to be precise (thanks @marcsdionne.bsky.social), they are considering implementing triage
BBSRC to implement triage of proposals pre-panel and rolling deadlines to reduce assessment burden. Interesting times ahead!
September 10, 2025 at 11:20 AM
BBSRC to implement triage of proposals pre-panel and rolling deadlines to reduce assessment burden. Interesting times ahead!
Reposted by Jose Jimenez
Please re-post:
Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...
Abstract deadline: 30 September
Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...
Abstract deadline: 30 September
EvoChromo: Evolutionary approaches to research in chromatin
Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…
meetings.embo.org
September 8, 2025 at 11:14 AM
Please re-post:
Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...
Abstract deadline: 30 September
Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...
Abstract deadline: 30 September
Slightly diminish a band:
Joy Subtraction
Joy Subtraction
Slightly diminish a band:
Pearl Jelly
Pearl Jelly
Slightly diminish a band:
Moyen Jovi
Moyen Jovi
August 13, 2025 at 8:53 AM
Slightly diminish a band:
Joy Subtraction
Joy Subtraction
Reposted by Jose Jimenez
I am excited to announce that the position of a senior postdoc (3 +3 years) in the field of theoretical biology is available in my group.
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Details 👇:
shorturl.at/iiiOv
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Details 👇:
shorturl.at/iiiOv
116 FB 5 Research Assistant (m/f/d) field of Theoretical Ecology and Evolution or Computational Biology: Uni Osnabrück
shorturl.at
August 8, 2025 at 10:09 AM
I am excited to announce that the position of a senior postdoc (3 +3 years) in the field of theoretical biology is available in my group.
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Details 👇:
shorturl.at/iiiOv
The position provides the opportunity to closely interact with experimentalists and develop own research projects.
Please RT.
Details 👇:
shorturl.at/iiiOv
Excited to be at the MRC Laboratory of Molecular Biology (LMB) for the first time to present at the Life Sciences Students Symposium. Such impressive venue. No pressure!
July 11, 2025 at 1:44 PM
Excited to be at the MRC Laboratory of Molecular Biology (LMB) for the first time to present at the Life Sciences Students Symposium. Such impressive venue. No pressure!
Appealing to the wisdom of the crowd: Let's say molecule X produced by microbe Y is used as an 'organic' fertiliser. If molecule X is produced recombinantly in microbe Z, purified and used as a fertiliser, could this process receive 'organic certification'?
July 8, 2025 at 11:33 AM
Appealing to the wisdom of the crowd: Let's say molecule X produced by microbe Y is used as an 'organic' fertiliser. If molecule X is produced recombinantly in microbe Z, purified and used as a fertiliser, could this process receive 'organic certification'?