Jingxun Chen
@jingxunchen.bsky.social
Postdoc at Brunet lab, Stanford. Study sexual reproduction, mating & aging in killifish. Educator. Arts enthusiast.
Reposted by Jingxun Chen
📣 103 participants and counting…
The 2025 Nothobranchius Symposium is fast approaching!
🧬 Join us in beautiful Jena, Germany, June 5–6, 2025, for cutting-edge talks on #killifish.
📝 Abstracts accepted until April 22
🔗 notho-2025.de
We look forward to meeting you at #Notho25!
The 2025 Nothobranchius Symposium is fast approaching!
🧬 Join us in beautiful Jena, Germany, June 5–6, 2025, for cutting-edge talks on #killifish.
📝 Abstracts accepted until April 22
🔗 notho-2025.de
We look forward to meeting you at #Notho25!
April 7, 2025 at 9:46 AM
📣 103 participants and counting…
The 2025 Nothobranchius Symposium is fast approaching!
🧬 Join us in beautiful Jena, Germany, June 5–6, 2025, for cutting-edge talks on #killifish.
📝 Abstracts accepted until April 22
🔗 notho-2025.de
We look forward to meeting you at #Notho25!
The 2025 Nothobranchius Symposium is fast approaching!
🧬 Join us in beautiful Jena, Germany, June 5–6, 2025, for cutting-edge talks on #killifish.
📝 Abstracts accepted until April 22
🔗 notho-2025.de
We look forward to meeting you at #Notho25!
Reposted by Jingxun Chen
Oligomeric RNA cryoEM structures revealed by Zhaoming Su and colleagues @science.org. Structural motifs that contribute to RNA multivalency: kissing loop, palindromic base-pairing, A-stacking, metal coordination, pseudoknot, minor-groove. First glimpse into molecular interactions of RNA multivalency
March 14, 2025 at 1:01 AM
Oligomeric RNA cryoEM structures revealed by Zhaoming Su and colleagues @science.org. Structural motifs that contribute to RNA multivalency: kissing loop, palindromic base-pairing, A-stacking, metal coordination, pseudoknot, minor-groove. First glimpse into molecular interactions of RNA multivalency
Reposted by Jingxun Chen
Many US students don’t know how to seek opportunities outside the US. With some help from our colleagues in EU and Canada, we could put together a consolidated website of PhD opportunities and scholarships outside the US, organized by field. There might still be time for this year in some places.
I’m having similar conversations and sharing international opportunities a lot. I’m sure for a lot of US based trainees that feels overwhelming. I moved to Europe for my postdoc.Happy to chat with any trainees about my experience if it would be helpful.
Heartbreaking chats this week with students thinking of giving up on their dreams of getting a PhD. They worry about getting in PhD programs and careers post PhD. My suggestions: don’t be hasty, think broadly incl EU & Canada, & careers beyond traditional academia. What’re you telling your students?
March 1, 2025 at 4:17 AM
Many US students don’t know how to seek opportunities outside the US. With some help from our colleagues in EU and Canada, we could put together a consolidated website of PhD opportunities and scholarships outside the US, organized by field. There might still be time for this year in some places.
Reposted by Jingxun Chen
Cool paper using LLM to discover a protein sequence code for subcellular localization 👏
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Protein codes promote selective subcellular compartmentalization
Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...
www.science.org
February 9, 2025 at 12:46 AM
Cool paper using LLM to discover a protein sequence code for subcellular localization 👏
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Jingxun Chen
Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation
Ribosomes cooperate through transient collisions to ensure efficient translation.
www.cell.com
February 3, 2025 at 7:38 AM
Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Jingxun Chen
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
Organelle proteomics defines the cellular landscape of protein localization and highlights the role of subcellular remodeling in driving responses to perturbations such as viral infections.
www.cell.com
January 1, 2025 at 1:47 PM
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Jingxun Chen
✨✨The 2025 Keystone Symposium on Aging and Gerotherapeutics is coming up and early bird registration ends today! Very excited about our speaker lineup. Check it out!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Aging: New Frontiers in Rejuvenation and Gerotherapeutics | Keystone Symposia
Join us at the Keystone Symposia on Aging: New Frontiers in Rejuvenation and Gerotherapeutics, February 2025, in Breckenridge, with field leaders!
www.keystonesymposia.org
December 23, 2024 at 8:47 PM
✨✨The 2025 Keystone Symposium on Aging and Gerotherapeutics is coming up and early bird registration ends today! Very excited about our speaker lineup. Check it out!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Reposted by Jingxun Chen
Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 23, 2024 at 5:49 PM
Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Jingxun Chen
Thrilled to see this paper out!! 🧪
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomic clocks reveal cell proximity effects in brain ageing
Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...
rdcu.be
December 18, 2024 at 10:40 PM
Thrilled to see this paper out!! 🧪
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵
Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!
Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!
rdcu.be/d33uQ 🧵