Ines Sturmlechner
@inessturmlechner.bsky.social
Post-doc, K99 awardee, studying the aging immune system at Mayo Clinic, Leading Edge fellow, former AFAR/Glenn Foundation fellow | PhD, cellular senescence at University Groningen and Mayo Clinic | MSc, tRNA maturation at IMBA Vienna
Pinned
Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells - Nature Communications
Homeostasis of memory T cells is modulated by each antigen encounter, thereby creating a heterogeneous population preventing precise tracking. Here, the authors use barcode-assisted tracing of Epstein...
www.nature.com
I’m excited to share our new T cell aging study published in Nature Communications @natcomms.nature.com !
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
Reposted by Ines Sturmlechner
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
Reposted by Ines Sturmlechner
Get your Zoster vaccine! @naturemedicine.bsky.social
A consistent relationship of VZV reactivation with dementia in 100M US adults after controlling for nearly 400 measured characteristics, with zoster vaccines reducing risk of dementia in dose-dependent manner
www.nature.com/articles/s41...
A consistent relationship of VZV reactivation with dementia in 100M US adults after controlling for nearly 400 measured characteristics, with zoster vaccines reducing risk of dementia in dose-dependent manner
www.nature.com/articles/s41...
October 6, 2025 at 8:27 PM
Get your Zoster vaccine! @naturemedicine.bsky.social
A consistent relationship of VZV reactivation with dementia in 100M US adults after controlling for nearly 400 measured characteristics, with zoster vaccines reducing risk of dementia in dose-dependent manner
www.nature.com/articles/s41...
A consistent relationship of VZV reactivation with dementia in 100M US adults after controlling for nearly 400 measured characteristics, with zoster vaccines reducing risk of dementia in dose-dependent manner
www.nature.com/articles/s41...
Reposted by Ines Sturmlechner
Applications are now open for the Salk SURF — a fully funded, 10-week program that gives undergraduate students access to world-class facilities, mentorship from leading scientists, and a supportive community of peers.
📅 Deadline: December 7, 2025
Apply today: www.salk.edu/about/our-communi...
📅 Deadline: December 7, 2025
Apply today: www.salk.edu/about/our-communi...
October 6, 2025 at 7:51 PM
Applications are now open for the Salk SURF — a fully funded, 10-week program that gives undergraduate students access to world-class facilities, mentorship from leading scientists, and a supportive community of peers.
📅 Deadline: December 7, 2025
Apply today: www.salk.edu/about/our-communi...
📅 Deadline: December 7, 2025
Apply today: www.salk.edu/about/our-communi...
Reposted by Ines Sturmlechner
Research Spotlight: Dr. @inessturmlechner.bsky.social, PhD – Mayo Clinic
Her new Nature Communications study reveals how antigen specificity shapes aging paths of memory CD8⁺ T cells, explaining immune decline & infection risk in older adults.
👉 Read: www.nature.com/articles/s41...
#AgingResearch
Her new Nature Communications study reveals how antigen specificity shapes aging paths of memory CD8⁺ T cells, explaining immune decline & infection risk in older adults.
👉 Read: www.nature.com/articles/s41...
#AgingResearch
September 18, 2025 at 7:50 PM
Research Spotlight: Dr. @inessturmlechner.bsky.social, PhD – Mayo Clinic
Her new Nature Communications study reveals how antigen specificity shapes aging paths of memory CD8⁺ T cells, explaining immune decline & infection risk in older adults.
👉 Read: www.nature.com/articles/s41...
#AgingResearch
Her new Nature Communications study reveals how antigen specificity shapes aging paths of memory CD8⁺ T cells, explaining immune decline & infection risk in older adults.
👉 Read: www.nature.com/articles/s41...
#AgingResearch
Reposted by Ines Sturmlechner
Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!
July 26, 2025 at 2:30 PM
Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!
Reposted by Ines Sturmlechner
This story was made possible thanks to NIH staff who reached out. I'm always looking for more sources, message me on Signal (mkozlov.01).
If you hit a paywall, making a free account will open the full story.
If you hit a paywall, making a free account will open the full story.
Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities
The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.
www.nature.com
July 14, 2025 at 11:25 PM
This story was made possible thanks to NIH staff who reached out. I'm always looking for more sources, message me on Signal (mkozlov.01).
If you hit a paywall, making a free account will open the full story.
If you hit a paywall, making a free account will open the full story.
I’m excited to share our new T cell aging study published in Nature Communications @natcomms.nature.com !
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells - Nature Communications
Homeostasis of memory T cells is modulated by each antigen encounter, thereby creating a heterogeneous population preventing precise tracking. Here, the authors use barcode-assisted tracing of Epstein...
www.nature.com
July 14, 2025 at 12:16 PM
I’m excited to share our new T cell aging study published in Nature Communications @natcomms.nature.com !
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
We show that T cells do not age uniformly but undergo distinct aging trajectories even if they were primed simultaneously early in life.
www.nature.com/articles/s41...
👇👇
Reposted by Ines Sturmlechner
✨✨ #GLAM2025 ✨✨ is back 9/5/2025 to showcase #geroscience trainee research! Registration and poster submission are open (and #FlashTalk selection for #undergrads!).
Event website: gero.usc.edu/laara/event/...
Thanks to @activemotifusa.bsky.social, #Hevolution and #VWR for their support!
Event website: gero.usc.edu/laara/event/...
Thanks to @activemotifusa.bsky.social, #Hevolution and #VWR for their support!
July 11, 2025 at 3:21 PM
✨✨ #GLAM2025 ✨✨ is back 9/5/2025 to showcase #geroscience trainee research! Registration and poster submission are open (and #FlashTalk selection for #undergrads!).
Event website: gero.usc.edu/laara/event/...
Thanks to @activemotifusa.bsky.social, #Hevolution and #VWR for their support!
Event website: gero.usc.edu/laara/event/...
Thanks to @activemotifusa.bsky.social, #Hevolution and #VWR for their support!
Reposted by Ines Sturmlechner
Inflammation, thought to be a driver of age-related disease, does not worsen with age in some Indigenous communities
https://go.nature.com/45NHWSr
https://go.nature.com/45NHWSr
Ageing is linked to inflammation — but only in the industrialized world
Inflammation, thought to be a driver of age-related disease, does not worsen with age in some Indigenous communities.
go.nature.com
June 30, 2025 at 3:28 PM
Inflammation, thought to be a driver of age-related disease, does not worsen with age in some Indigenous communities
https://go.nature.com/45NHWSr
https://go.nature.com/45NHWSr
Reposted by Ines Sturmlechner
🚨 Preprint alert 🚨 , spearheaded by the talented Mr. #RyanLu, a graduate student: "Murine peritoneal macrophages undergo female-specific remodeling with aging", a functional genomics study of sex-dimorphism ♀️♂️ in #immune #aging 🖥️🧬🧪. #GeroSky #ImmunoSky 🧵, 1/13
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 18, 2025 at 4:00 PM
🚨 Preprint alert 🚨 , spearheaded by the talented Mr. #RyanLu, a graduate student: "Murine peritoneal macrophages undergo female-specific remodeling with aging", a functional genomics study of sex-dimorphism ♀️♂️ in #immune #aging 🖥️🧬🧪. #GeroSky #ImmunoSky 🧵, 1/13
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ines Sturmlechner
Preprint: Antigen-specific Th17 T cells offset the age-related decline in durable T cell immunity
www.biorxiv.org/content/10.1...
@inessturmlechner.bsky.social
www.biorxiv.org/content/10.1...
@inessturmlechner.bsky.social
June 7, 2025 at 3:05 AM
Preprint: Antigen-specific Th17 T cells offset the age-related decline in durable T cell immunity
www.biorxiv.org/content/10.1...
@inessturmlechner.bsky.social
www.biorxiv.org/content/10.1...
@inessturmlechner.bsky.social
I’m so excited and honored to be part of this incredible community!
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
May 27, 2025 at 11:14 PM
I’m so excited and honored to be part of this incredible community!
Reposted by Ines Sturmlechner
Call for Applications! The 32nd Annual NIA Training Course provides intense exposure to current concepts in experimental aging research for a cohort of 15-20 research scientists. Applications are due July 1, 2025. Learn more here: bit.ly/44y6RIY
May 14, 2025 at 12:50 PM
Call for Applications! The 32nd Annual NIA Training Course provides intense exposure to current concepts in experimental aging research for a cohort of 15-20 research scientists. Applications are due July 1, 2025. Learn more here: bit.ly/44y6RIY
Reposted by Ines Sturmlechner
Super excited to announce our new paper (and tool) spearheaded by
@hasansiam.xyz
! CAFE (cell analyzer for flow experiments) is a user-friendly web app to analyze flow cytometry data. No coding required! Check out the paper academic.oup.com/bioinformati... 🔬💻
@hasansiam.xyz
! CAFE (cell analyzer for flow experiments) is a user-friendly web app to analyze flow cytometry data. No coding required! Check out the paper academic.oup.com/bioinformati... 🔬💻
April 25, 2025 at 4:47 PM
Super excited to announce our new paper (and tool) spearheaded by
@hasansiam.xyz
! CAFE (cell analyzer for flow experiments) is a user-friendly web app to analyze flow cytometry data. No coding required! Check out the paper academic.oup.com/bioinformati... 🔬💻
@hasansiam.xyz
! CAFE (cell analyzer for flow experiments) is a user-friendly web app to analyze flow cytometry data. No coding required! Check out the paper academic.oup.com/bioinformati... 🔬💻
Reposted by Ines Sturmlechner
Interested in aging?
Super excited about this upcoming Keystone meeting!! 🧪🌲🌲
Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨
Joint meeting with the Keystone Innate Immunity meeting!
#aging #immunity @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
Super excited about this upcoming Keystone meeting!! 🧪🌲🌲
Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨
Joint meeting with the Keystone Innate Immunity meeting!
#aging #immunity @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
Aging: Immune Function and Organ Health | Keystone Symposia
Join us at the Keystone Symposia on Aging: Immune Function and Organ Health, March 2026, in Banff, with field leaders!
www.keystonesymposia.org
March 22, 2025 at 12:55 AM
Interested in aging?
Super excited about this upcoming Keystone meeting!! 🧪🌲🌲
Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨
Joint meeting with the Keystone Innate Immunity meeting!
#aging #immunity @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
Super excited about this upcoming Keystone meeting!! 🧪🌲🌲
Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨
Joint meeting with the Keystone Innate Immunity meeting!
#aging #immunity @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
Reposted by Ines Sturmlechner
Just found this account celebrating the achievements of women👇🏽
1/ Frances Elizabeth Allen (1932–2020) was an American computer scientist and pioneer in the field of optimizing compilers. #WomenInSTEM
January 18, 2025 at 3:22 PM
Just found this account celebrating the achievements of women👇🏽
Reposted by Ines Sturmlechner
Applications are now open for the NIA Butler-Williams Scholars Program which provides unique opportunities for new/junior investigators to gain insight about #AgingResearch. Learn more and apply here: bit.ly/4h9NQiX
January 10, 2025 at 5:34 PM
Applications are now open for the NIA Butler-Williams Scholars Program which provides unique opportunities for new/junior investigators to gain insight about #AgingResearch. Learn more and apply here: bit.ly/4h9NQiX
Reposted by Ines Sturmlechner
Biological sex is a key modifier of #aging phenotypes, including #Brain 🧠 aging.
See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic:
www.sciencedirect.com/science/arti...
#GeroSky #SexDifferences
See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic:
www.sciencedirect.com/science/arti...
#GeroSky #SexDifferences
January 8, 2025 at 4:54 PM
Biological sex is a key modifier of #aging phenotypes, including #Brain 🧠 aging.
See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic:
www.sciencedirect.com/science/arti...
#GeroSky #SexDifferences
See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic:
www.sciencedirect.com/science/arti...
#GeroSky #SexDifferences