Leonhard Held
@heldleonhard.bsky.social
Professor of Biostatistics at University of Zurich, Director UZH Center for Reproducible Science and Master Biostats, Steering committee Swiss Reproducibility Network (SwissRN)
Pinned
Leonhard Held
@heldleonhard.bsky.social
· Feb 25
A comparison of combined p-value functions for meta-analysis
P-value functions are modern statistical tools that unify effect estimation and hypothesis testing and can provide alternative point and interval estimates compared to standard meta-analysis methods, ...
arxiv.org
Tired of fixed effect and random-effects meta-analysis?
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
Reposted by Leonhard Held
Our SwissRN Academy offers a free "Early Career Reviewer Workshop" at the University of Bern. Early career researchers will gain valuable experience in scientific peer review.
Date: September 11, 2025 (10:00 - 16:00)
Registration: Register by August 25 via forms.office.com/e/V3QEAFbN84
Date: September 11, 2025 (10:00 - 16:00)
Registration: Register by August 25 via forms.office.com/e/V3QEAFbN84
July 30, 2025 at 12:44 PM
Our SwissRN Academy offers a free "Early Career Reviewer Workshop" at the University of Bern. Early career researchers will gain valuable experience in scientific peer review.
Date: September 11, 2025 (10:00 - 16:00)
Registration: Register by August 25 via forms.office.com/e/V3QEAFbN84
Date: September 11, 2025 (10:00 - 16:00)
Registration: Register by August 25 via forms.office.com/e/V3QEAFbN84
Reposted by Leonhard Held
🇨🇭🇪🇺 Just Published in Royal Society Open Science!
A scoping review on metrics to quantify reproducibility:
royalsocietypublishing.org/doi/10.1098/...
Ever conducted a replication and pondered when/how to conclude if it was (un)successful?
We have just the paper for you (led by Rachel Heyard)! 1/14
A scoping review on metrics to quantify reproducibility:
royalsocietypublishing.org/doi/10.1098/...
Ever conducted a replication and pondered when/how to conclude if it was (un)successful?
We have just the paper for you (led by Rachel Heyard)! 1/14
July 21, 2025 at 8:41 AM
🇨🇭🇪🇺 Just Published in Royal Society Open Science!
A scoping review on metrics to quantify reproducibility:
royalsocietypublishing.org/doi/10.1098/...
Ever conducted a replication and pondered when/how to conclude if it was (un)successful?
We have just the paper for you (led by Rachel Heyard)! 1/14
A scoping review on metrics to quantify reproducibility:
royalsocietypublishing.org/doi/10.1098/...
Ever conducted a replication and pondered when/how to conclude if it was (un)successful?
We have just the paper for you (led by Rachel Heyard)! 1/14
Reposted by Leonhard Held
🎉 Big news for clinical research! SPIRIT2025 just dropped, adding an Open Science section & a new Item No. 6 on data sharing. This pushes transparency in trials—where & how de-identified data, code, & materials will be accessible. Check it: www.consort-spirit.org #OpenScience #ClinicalTrials
Home | consort-spirit.org
www.consort-spirit.org
May 19, 2025 at 2:58 PM
🎉 Big news for clinical research! SPIRIT2025 just dropped, adding an Open Science section & a new Item No. 6 on data sharing. This pushes transparency in trials—where & how de-identified data, code, & materials will be accessible. Check it: www.consort-spirit.org #OpenScience #ClinicalTrials
Perplexing!
Plenty of tortured phrases (arxiv.org/abs/2107.0...) in this #IEEE paper. ieeexplore.ieee.org/...
My pubpeer report: pubpeer.com/publicat...
My pubpeer report: pubpeer.com/publicat...
May 14, 2025 at 7:21 PM
Perplexing!
Reposted by Leonhard Held
Plenty of tortured phrases (arxiv.org/abs/2107.0...) in this #IEEE paper. ieeexplore.ieee.org/...
My pubpeer report: pubpeer.com/publicat...
My pubpeer report: pubpeer.com/publicat...
May 12, 2025 at 5:30 AM
Plenty of tortured phrases (arxiv.org/abs/2107.0...) in this #IEEE paper. ieeexplore.ieee.org/...
My pubpeer report: pubpeer.com/publicat...
My pubpeer report: pubpeer.com/publicat...
Reposted by Leonhard Held
UHaveIntegrity: A Strengths-Based Approach to Academic Integrity at the University of Calgary buff.ly/yRXDrNS
UHaveIntegrity: A Strengths-Based Approach to Academic Integrity at the University of Calgary
The #UHaveIntegrity campaign at the University of Calgary reframes academic integrity by focusing on students’ existing ethical foundations rather than viewing them as potential cheaters. It …
buff.ly
May 11, 2025 at 12:34 AM
UHaveIntegrity: A Strengths-Based Approach to Academic Integrity at the University of Calgary buff.ly/yRXDrNS
Reposted by Leonhard Held
Transparency in research takes another step forward.
Join our April 2, 2025 webinar to explore Retraction Watch data in Crossref. Find out how it works and why it matters.
Register: https://tinyurl.com/tbf8w6u7
#Crossref #publishing #research
Join our April 2, 2025 webinar to explore Retraction Watch data in Crossref. Find out how it works and why it matters.
Register: https://tinyurl.com/tbf8w6u7
#Crossref #publishing #research
March 25, 2025 at 4:11 PM
Transparency in research takes another step forward.
Join our April 2, 2025 webinar to explore Retraction Watch data in Crossref. Find out how it works and why it matters.
Register: https://tinyurl.com/tbf8w6u7
#Crossref #publishing #research
Join our April 2, 2025 webinar to explore Retraction Watch data in Crossref. Find out how it works and why it matters.
Register: https://tinyurl.com/tbf8w6u7
#Crossref #publishing #research
Reposted by Leonhard Held
Hey there! We are ReproducibiliTea Geneva👋
As part of the @reproducibilitea.org community, we meet regularly at the University of Geneva to discuss all things open and reproducible science, in a relaxed atmosphere over a cup of tea🫖📚! Feel free to get in touch!
As part of the @reproducibilitea.org community, we meet regularly at the University of Geneva to discuss all things open and reproducible science, in a relaxed atmosphere over a cup of tea🫖📚! Feel free to get in touch!
March 18, 2025 at 4:20 PM
Hey there! We are ReproducibiliTea Geneva👋
As part of the @reproducibilitea.org community, we meet regularly at the University of Geneva to discuss all things open and reproducible science, in a relaxed atmosphere over a cup of tea🫖📚! Feel free to get in touch!
As part of the @reproducibilitea.org community, we meet regularly at the University of Geneva to discuss all things open and reproducible science, in a relaxed atmosphere over a cup of tea🫖📚! Feel free to get in touch!
Reposted by Leonhard Held
Retraction @plosone.org - paper with authors from Ghent University.
"All authors either did not respond directly or could not be reached."
Does any journalist in Belgium want to write about this? It's so strange that none of the authors responded.
pubpeer.com/publications...
"All authors either did not respond directly or could not be reached."
Does any journalist in Belgium want to write about this? It's so strange that none of the authors responded.
pubpeer.com/publications...
March 13, 2025 at 8:39 PM
Retraction @plosone.org - paper with authors from Ghent University.
"All authors either did not respond directly or could not be reached."
Does any journalist in Belgium want to write about this? It's so strange that none of the authors responded.
pubpeer.com/publications...
"All authors either did not respond directly or could not be reached."
Does any journalist in Belgium want to write about this? It's so strange that none of the authors responded.
pubpeer.com/publications...
Reposted by Leonhard Held
🚨Huge issue!
Needed: Quality > Quantity
Scientists see signs of trouble with quality at the biggest scientific journals www.wsj.com/business/med...
"Some of the work that has been published is so seriously flawed that it is not credible that it underwent any meaningful form of peer review."
Needed: Quality > Quantity
Scientists see signs of trouble with quality at the biggest scientific journals www.wsj.com/business/med...
"Some of the work that has been published is so seriously flawed that it is not credible that it underwent any meaningful form of peer review."
Scientists Take on Scholarly Journals With Walkouts, Scathing Letters and Delistings
Some scientists say the for-profit industry’s fast growth makes it harder to police fraud and low-quality work.
www.wsj.com
March 13, 2025 at 9:07 PM
🚨Huge issue!
Needed: Quality > Quantity
Scientists see signs of trouble with quality at the biggest scientific journals www.wsj.com/business/med...
"Some of the work that has been published is so seriously flawed that it is not credible that it underwent any meaningful form of peer review."
Needed: Quality > Quantity
Scientists see signs of trouble with quality at the biggest scientific journals www.wsj.com/business/med...
"Some of the work that has been published is so seriously flawed that it is not credible that it underwent any meaningful form of peer review."
Very pleased to see #reproducibility #transparency #integrity #openscience emphasized to ensure trust in science in Switzerland and beyond
All part of the @swissrn.bsky.social strategy:
www.swissrn.org/contents/com...
Truth and trust are pillars for research www.horizons-mag.ch/2025/03/06/t...
All part of the @swissrn.bsky.social strategy:
www.swissrn.org/contents/com...
Truth and trust are pillars for research www.horizons-mag.ch/2025/03/06/t...
Truth and trust are pillars for research
Horizons - Issue 144
www.horizons-mag.ch
March 13, 2025 at 7:27 PM
Very pleased to see #reproducibility #transparency #integrity #openscience emphasized to ensure trust in science in Switzerland and beyond
All part of the @swissrn.bsky.social strategy:
www.swissrn.org/contents/com...
Truth and trust are pillars for research www.horizons-mag.ch/2025/03/06/t...
All part of the @swissrn.bsky.social strategy:
www.swissrn.org/contents/com...
Truth and trust are pillars for research www.horizons-mag.ch/2025/03/06/t...
Reposted by Leonhard Held
🕓Today at 4pm (CET): Join the 2024 #EinsteinFoundationAward winners' colloquium on scientific integrity with @elisabethbik.bsky.social, @brandonstell.bsky.social from @pubpeer.com, and @helenajambor.bsky.social and Christopher Schmied from PixelQuality via Livestream: www.youtube.com/live/ZZ5R8CG...
2024 Einstein Foundation Award Winners Colloquium
YouTube video by Einstein Foundation Berlin
www.youtube.com
March 13, 2025 at 11:19 AM
🕓Today at 4pm (CET): Join the 2024 #EinsteinFoundationAward winners' colloquium on scientific integrity with @elisabethbik.bsky.social, @brandonstell.bsky.social from @pubpeer.com, and @helenajambor.bsky.social and Christopher Schmied from PixelQuality via Livestream: www.youtube.com/live/ZZ5R8CG...
Highly recommended!
How avoidance of research waste is now emphasized in the Declaration of Helsinki, and how you might want to improve some of your data management and analysis practices in light of this change (talk, 40 minutes).
www.youtube.com/watch?v=q1nb...
www.youtube.com/watch?v=q1nb...
The Declaration of Helsinki now says you should avoid research waste. Here's how.
YouTube video by Darren Dahly
www.youtube.com
March 10, 2025 at 7:43 AM
Highly recommended!
Welcome to Zurich, Tobias! Looking forward to interact on Open and Reproducible Science
I have some exciting personal news to share:
On April 1st, I'll join @ikmz.bsky.social at University of Zurich for a professorship labelled Media Psychology and Methods!
I'm quite excited and very much looking forward to this new chapter and incredible opportunity!
On April 1st, I'll join @ikmz.bsky.social at University of Zurich for a professorship labelled Media Psychology and Methods!
I'm quite excited and very much looking forward to this new chapter and incredible opportunity!
a small bird is standing on a wooden table next to a tissue box holder .
Alt: a small bird is standing on a wooden table next to a tissue box holder, jumping around and being incredibly happy
media.tenor.com
February 27, 2025 at 5:10 PM
Welcome to Zurich, Tobias! Looking forward to interact on Open and Reproducible Science
Tired of fixed effect and random-effects meta-analysis?
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
A comparison of combined p-value functions for meta-analysis
P-value functions are modern statistical tools that unify effect estimation and hypothesis testing and can provide alternative point and interval estimates compared to standard meta-analysis methods, ...
arxiv.org
February 25, 2025 at 10:25 PM
Tired of fixed effect and random-effects meta-analysis?
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
Check out our revised manuscript on p-value combination methods for meta-analysis:
arxiv.org/abs/2408.08135
"The most expensive, most widespread example of catastrophic research fraud in the history of modern science?"
Listen to this, "if you love science and you want to see science done well".
podcastaddict.com/plain-englis...
Listen to this, "if you love science and you want to see science done well".
podcastaddict.com/plain-englis...
Plain English with Derek Thompson - Fraud, Scandal, and Failure in the Fight Against Alzheimer's Disease
Listen to Plain English with Derek Thompson - Fraud, Scandal, and Failure in the Fight Against Alzheimer's Disease by The Ringer on Podcast Addict. Why is it so hard to find a cure for Alzheimer’s? A simple answer is that the brain and its disorders are complicated. But as today’s guest, Charles Piller, writes, there’s another, more sinister factor at play. His new book, 'Doctored,' traces an incredible, true story of fraud, arrogance, and tragedy in the quest to cure Alzheimer’s.In the last few years, some of the most
podcastaddict.com
February 17, 2025 at 11:36 AM
"The most expensive, most widespread example of catastrophic research fraud in the history of modern science?"
Listen to this, "if you love science and you want to see science done well".
podcastaddict.com/plain-englis...
Listen to this, "if you love science and you want to see science done well".
podcastaddict.com/plain-englis...
Reposted by Leonhard Held
ICYMI: Second paper by Nobel laureate Thomas Südhof retracted
@retractionwatch.com
retractionwatch.com/2025/02/14/i...
@retractionwatch.com
retractionwatch.com/2025/02/14/i...
ICYMI: Second paper by Nobel laureate Thomas Südhof retracted
Thomas Südhof A 2017 paper coauthored by Nobel laureate Thomas Südhof has been retracted. The article, “Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer…
retractionwatch.com
February 15, 2025 at 7:03 AM
ICYMI: Second paper by Nobel laureate Thomas Südhof retracted
@retractionwatch.com
retractionwatch.com/2025/02/14/i...
@retractionwatch.com
retractionwatch.com/2025/02/14/i...
The Swiss Reproducibility Network (SwissRN) is now on Bluesky! Make sure to follow
@swissrn.bsky.social
@swissrn.bsky.social
February 14, 2025 at 5:40 PM
The Swiss Reproducibility Network (SwissRN) is now on Bluesky! Make sure to follow
@swissrn.bsky.social
@swissrn.bsky.social
Reposted by Leonhard Held
We’re pleased to join the UK Reproducibility Network (@ukrepro.bsky.social) as a stakeholder in support of a more open, transparent and reproducible research culture. Find out more:
UKRN welcomes eLife and Hidden REF as new stakeholders | UK Reproducibility Network
Feb 4, 2025 | News
www.ukrn.org
February 4, 2025 at 5:45 PM
We’re pleased to join the UK Reproducibility Network (@ukrepro.bsky.social) as a stakeholder in support of a more open, transparent and reproducible research culture. Find out more:
Reposted by Leonhard Held
Are @zbmed.bsky.social aware of the negative reaction on social media to their just-announced contract with MDPI. There's a great many red flags they seem to have missed, e.g.
deevybee.blogspot.com/2024/08/gues...
deevybee.blogspot.com/2024/02/the-...
+ @hansonmark@bsky.social's account below
deevybee.blogspot.com/2024/08/gues...
deevybee.blogspot.com/2024/02/the-...
+ @hansonmark@bsky.social's account below
December 21, 2024 at 1:20 PM
Are @zbmed.bsky.social aware of the negative reaction on social media to their just-announced contract with MDPI. There's a great many red flags they seem to have missed, e.g.
deevybee.blogspot.com/2024/08/gues...
deevybee.blogspot.com/2024/02/the-...
+ @hansonmark@bsky.social's account below
deevybee.blogspot.com/2024/08/gues...
deevybee.blogspot.com/2024/02/the-...
+ @hansonmark@bsky.social's account below
Reposted by Leonhard Held
Why probability probably doesn’t exist (but it is useful to act like it does) - by D. Spiegelhalter
www.nature.com/articles/d41...
A great article highlighting the subjective nature of uncertainty, particularly relevant to our thinking about the nature of anxiety.
www.nature.com/articles/d41...
A great article highlighting the subjective nature of uncertainty, particularly relevant to our thinking about the nature of anxiety.
Why probability probably doesn’t exist (but it is useful to act like it does)
All of statistics and much of science depends on probability — an astonishing achievement, considering no one’s really sure what it is.
www.nature.com
December 20, 2024 at 11:19 AM
Why probability probably doesn’t exist (but it is useful to act like it does) - by D. Spiegelhalter
www.nature.com/articles/d41...
A great article highlighting the subjective nature of uncertainty, particularly relevant to our thinking about the nature of anxiety.
www.nature.com/articles/d41...
A great article highlighting the subjective nature of uncertainty, particularly relevant to our thinking about the nature of anxiety.
Reposted by Leonhard Held
Big news from Finnish publication forum. Almost all MDPI and Frontiers journals will be downgraded to level 0 and thus are not considered as properly peer reviewed trustworthy scientific journals.
julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi/en/news/chan...
Changes to the classification
julkaisufoorumi.fi
December 16, 2024 at 10:12 AM
Big news from Finnish publication forum. Almost all MDPI and Frontiers journals will be downgraded to level 0 and thus are not considered as properly peer reviewed trustworthy scientific journals.
julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi/en/news/chan...
Reposted by Leonhard Held
ICYMI from earlier in 2024:
Reporting on data sharing: executive position of the EQUATOR Network published in the @bmj.com
www.bmj.com/content/386/...
#transparency #researchintegrity #datasharing #openscience #codesharing #reproducibility #metascience
Reporting on data sharing: executive position of the EQUATOR Network published in the @bmj.com
www.bmj.com/content/386/...
#transparency #researchintegrity #datasharing #openscience #codesharing #reproducibility #metascience
December 13, 2024 at 9:07 AM
ICYMI from earlier in 2024:
Reporting on data sharing: executive position of the EQUATOR Network published in the @bmj.com
www.bmj.com/content/386/...
#transparency #researchintegrity #datasharing #openscience #codesharing #reproducibility #metascience
Reporting on data sharing: executive position of the EQUATOR Network published in the @bmj.com
www.bmj.com/content/386/...
#transparency #researchintegrity #datasharing #openscience #codesharing #reproducibility #metascience
Reposted by Leonhard Held
Another day, another retraction. I complained about this article to the journal in June 2023 - I've been told the first time the editors were notified about it was way back in 2021:
obgyn.onlinelibrary.wiley.com/doi/10.1002/...
obgyn.onlinelibrary.wiley.com/doi/10.1002/...
OBGYN
Click on the article title to read more.
obgyn.onlinelibrary.wiley.com
December 1, 2024 at 9:00 PM
Another day, another retraction. I complained about this article to the journal in June 2023 - I've been told the first time the editors were notified about it was way back in 2021:
obgyn.onlinelibrary.wiley.com/doi/10.1002/...
obgyn.onlinelibrary.wiley.com/doi/10.1002/...