Density animation generated using ChimeraX, using "cootmode" display settings from chimerax-trimmings.

Movie recorded thusly:

cofr showpivot false; movie record; rock y 30; wait 600; movie encode ~/Desktop/rock_movie_more.mp4 framerate 40; stop

🇨🇦🚨Job Alert🚨🇨🇦
Canada Excellence Research Chair (C$5 or C$10M, 8 yr budget)
U Toronto, Dept of Biochem/LabMedPath
*Was just told they're looking for a structural biologist using cryoEM* (related to infectious disease?)
Are you an established PI ready to move to 🇨🇦?
research.utoronto.ca/funding-oppo...

Thrilled to announce my first PhD publication in Nature Comms! We determined structures of the Tad pilus ATPase CpaF from Caulobacter. We use these structures to propose how CpaF employs a rotary mechanism of catalysis to drive Tad pilus assembly.
www.nature.com/articles/s41...

We are excited to spotlight this structure of the type 3 ryanodine receptor determined by Yu Seby Chen and colleagues from UBC and the University of Siena!

It was a pleasure to collaborate with the Van Petegem (@filipvanpetegem.bsky.social) Lab on this lovely work!

www.nature.com/articles/s41...

There is an exciting opportunity available to work in the vibrant cryoEM community here in Toronto! 🇨🇦

Happy to field informal inquiries about the position or about uprooting and moving to Toronto as a recent Torontonian myself!

Please share widely.

jobs.utoronto.ca/job/Toronto-...

Now published J. Med. Chem! @zestytoast.bsky.social's structure of type II NADH dehydrogenase from mycobacteria. A promising drug target for TB & other mycobacterial infections, Yingke demonstrates how an inhibitor can block transfer of electrons from NADH to the ETC.
pubs.acs.org/doi/full/10....

I think it's important to reach out to your own community and explain what the funding cuts mean in practice.

Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma | Science Advances www.science.org/doi/10.1126/...

🚨 Amazing Opportunity 🚨
U Alberta is looking for a director for their new #cryoEM facility
Support excellent researchers (who are really nice people) using state-of-the-art infrastructure.
+ reasonable cost of living
+ near some of most beautiful places in world
+ 🇨🇦
apps.ualberta.ca/careers/post...

Most protein complexes are born only once. V-ATPase assembles over and over as part of its regulatory mechanism, enabled by RAVE (regulator of ATPase of vacuoles and endosomes)
@hanlinw222.bsky.social's 1st struct of RAVE bound to a partial V1 complex now out in PNAS.
www.pnas.org/doi/10.1073/...