Chair of ICBBS2026Sam-Yong Park (Yokohama City University)We are pleased to invite symposium proposals for International Conference on Biophysics and Biomedical Sciences (ICBBS2026).The Biophysical So...

High-sensitivity viral diagnostics typically use PCR to detect and amplify viral nucleic acids which requires fluorescence reporters, enzymatic amplification, specialized equipment and can be time-c...

YouTube video by The Biophysical Society of Japan

Consumer product companies have walked back their plastics sustainability goals, and many recyclers are closing their doors

The remarkable progress of artificial intelligence (AI) has revealed the enormous energy demands of modern digital architectures, raising deep concerns about sustainability. In stark contrast, the hum...

E. coli swims using helical flagellar filaments driven at their base by a rotary motor. Torque-generating ‘stator’ units drive the bacterial flagellar motor (BFM) by transmitting mechanical power to a...

The 2026 Gordon Research Conference on Single Molecule Approaches to Biology will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

We provide detailed experimental guidelines for implementing digital holography in the context of high-sensitivity interferometric scattering (iSCAT)-based nanosizing applications. Our approach relies on interferometry via the highly versatile off-axis implementation of digital holography, which offers key advantages over more traditional strategies. After a brief theoretical discussion of off-axis holography and its differences and similarities with iSCAT, typical experimental implementations and digital data-processing steps are presented. Key experimental parameters and strategies to achieve optimal performance are also highlighted. Following these experimental aspects, we focus on digital postprocessing routines that enable digital refocusing and 3D particle tracking as well as pupil function aberration correction. We then conclude with a few examples highlighting the broad applicability of digital holography for nanosizing and particle characterization applications, as well as an outlook for future applications.

Cryo-EM snapshots of the ATP synthase driven by proton motive force reveal the torsional deformation during ATP synthesis.

Molecular machine properties such as speed, efficiency, power, and torque depend upon particular features of structure, mechanism, and chemistry. The graphical abstract shows a Top Trumps-style repres...

Scalar energy can drive formation of non-equilibrium steady-states or power directional processes such as chemotaxis, ion transport across a membrane, or walking along a polar track. This work focuses...

An electrically driven DNA origami arm can exert piconewton forces and transport fluorophores and nanoparticles.

The bar-hinge motor: a synthetic protein design exploiting conformational switching to achieve directional motility, Small, Lara S R, Zuckermann, Martin J, Sessions, Richard B, Curmi, Paul M G, Linke,...

Abstract. RNase H cleaves RNA in RNA–DNA duplexes. It is present in all domains of life as well as in multiple viruses and is essential for mammalian devel

David Leigh earned a PhD in crown ether chemistry from the University of Sheffield in 1987 and has held professorial positions at the Universities of …

A microheater synchronizes the binding/unbinding of DNA sticky ends, increasing the strength and speed of DNA hinge machine.

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