Gallego Lab
@gallegolab.bsky.social
We are the Biophysics in Cell Biology lab! Creativity and light microscopy to study cell growth at @upfbarcelona.bsky.social 🌍 www.gallegolab.org
Pinned
Gallego Lab
@gallegolab.bsky.social
· Feb 12
Continuum architecture dynamics of vesicle tethering in exocytosis
Essential for eukaryotic organisms, multiple copies of the exocyst complex tether each secretory vesicle to the plasma membrane (PM) in constitutive exocytosis. The exocyst higher-order structure (ExH...
www.biorxiv.org
Interested in imaging protein suprastructures and membranes dynamics in situ? You also happen to be preoccupied by the exocyst? Read our latest preprint where we time-resolved the choreography of a flexible exocyst higher-order structure and the vesicle in exocytosis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Gallego Lab
MIRO is a graph neural network method that enhances spatial clustering for single-molecule localisation microscopy datasets. #BiotechNatureComms
@cmanzo.bsky.social @qubilab.bsky.social @giovannivolpe.bsky.social
doi.org/10.1038/s414...
@cmanzo.bsky.social @qubilab.bsky.social @giovannivolpe.bsky.social
doi.org/10.1038/s414...
Enhanced spatial clustering of single-molecule localizations with graph neural networks - Nature Communications
Single-molecule localisation microscopy enables nanoscale mapping of molecular organisation, but clustering stochastic data remains challenging. Here, authors present a graph neural network method tha...
doi.org
November 17, 2025 at 3:05 PM
MIRO is a graph neural network method that enhances spatial clustering for single-molecule localisation microscopy datasets. #BiotechNatureComms
@cmanzo.bsky.social @qubilab.bsky.social @giovannivolpe.bsky.social
doi.org/10.1038/s414...
@cmanzo.bsky.social @qubilab.bsky.social @giovannivolpe.bsky.social
doi.org/10.1038/s414...
Reposted by Gallego Lab
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
GitHub - aqlaboratory/openfold-3: OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3
OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3 - aqlaboratory/openfold-3
github.com
October 28, 2025 at 9:30 AM
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
Reposted by Gallego Lab
Calling all #Membrane enthusiasts!
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
October 27, 2025 at 5:02 PM
Calling all #Membrane enthusiasts!
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Reposted by Gallego Lab
💥Want to join us for a PhD in 2026?
The @crg.eu 2026 International PhD Programme is now open!
If you're passionate about cell biology and ready for an exciting research journey, apply now! ⏰
👉 Be part of the selection process: www.crg.eu/en/content/t...
@prbb.org
The @crg.eu 2026 International PhD Programme is now open!
If you're passionate about cell biology and ready for an exciting research journey, apply now! ⏰
👉 Be part of the selection process: www.crg.eu/en/content/t...
@prbb.org
October 23, 2025 at 9:27 AM
💥Want to join us for a PhD in 2026?
The @crg.eu 2026 International PhD Programme is now open!
If you're passionate about cell biology and ready for an exciting research journey, apply now! ⏰
👉 Be part of the selection process: www.crg.eu/en/content/t...
@prbb.org
The @crg.eu 2026 International PhD Programme is now open!
If you're passionate about cell biology and ready for an exciting research journey, apply now! ⏰
👉 Be part of the selection process: www.crg.eu/en/content/t...
@prbb.org
Reposted by Gallego Lab
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.
www.dundee.ac.uk/work-for-us/...
www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - MCDB - UOD2016
Closing date: Thursday 6 November 2025, 23:59
www.dundee.ac.uk
October 15, 2025 at 12:53 PM
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.
www.dundee.ac.uk/work-for-us/...
www.dundee.ac.uk/work-for-us/...
Great story, Magnaporthe orysae, biogenesis of the apressorium and assymetric distribution of organelles... And all is very well explained. Congrats!
I’m excited to share our new preprint from @talbotlabtsl.bsky.social lab!
🌱 Our latest study reveals how Magnaporthe oryzae synchronizes organelle trafficking and autophagy to infect plants. (1/13)
📄 Read more: doi.org/10.1101/2025...
🌱 Our latest study reveals how Magnaporthe oryzae synchronizes organelle trafficking and autophagy to infect plants. (1/13)
📄 Read more: doi.org/10.1101/2025...
Synchronous spatio-temporal control of autophagy and organelle trafficking is necessary for appressorium-mediated plant infection by Magnaporthe oryzae
The blast fungus Magnaporthe oryzae infects plants using a specialised infection structure called an appressorium that generates physical force to break the rice leaf cuticle. Appressorium development...
doi.org
October 12, 2025 at 7:15 PM
Great story, Magnaporthe orysae, biogenesis of the apressorium and assymetric distribution of organelles... And all is very well explained. Congrats!
Reposted by Gallego Lab
Reposted by Gallego Lab
GloBIAS conference Kobe 2025, the registration for the symposium is still open, until Sept 15th! bit.ly/GloBIAS2025-...
Bioimage Analysis Conference 2025 in Kobe
GloBIAS Bioimage Analysis Conference 2025
Oct 26, 2025 - Oct 31, 2025 | Kobe, Japan
Venue: RIKEN BDR, Kobe, Japan
Registration via Google Forms here:
https://tinyurl.com/3dtajhh6
General informatio...
bit.ly
September 10, 2025 at 8:57 AM
GloBIAS conference Kobe 2025, the registration for the symposium is still open, until Sept 15th! bit.ly/GloBIAS2025-...
Reposted by Gallego Lab
Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
September 9, 2025 at 2:16 PM
Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
Reposted by Gallego Lab
⁉️Have you ever wanted to capture tens of proteins in a single sample?
🧫 Check out our newly published Methods Chapter !
link.springer.com/protocol/10....
A huge thanks to Cyprien Noble, the @lucaspelkmans.bsky.social Lab, Marie-Hélène Verlhac @mhverlhac.bsky.social and Marie-Emilie Terret.
🧫 Check out our newly published Methods Chapter !
link.springer.com/protocol/10....
A huge thanks to Cyprien Noble, the @lucaspelkmans.bsky.social Lab, Marie-Hélène Verlhac @mhverlhac.bsky.social and Marie-Emilie Terret.
Highly Multiplexed Immunofluorescence Imaging of Mouse Oocytes
Highly multiplexed immunofluorescence imaging methods advanced our understanding of biology across scales, from tissues down to molecules. By enabling the visualization of tens of proteins in a single...
link.springer.com
September 5, 2025 at 2:39 PM
⁉️Have you ever wanted to capture tens of proteins in a single sample?
🧫 Check out our newly published Methods Chapter !
link.springer.com/protocol/10....
A huge thanks to Cyprien Noble, the @lucaspelkmans.bsky.social Lab, Marie-Hélène Verlhac @mhverlhac.bsky.social and Marie-Emilie Terret.
🧫 Check out our newly published Methods Chapter !
link.springer.com/protocol/10....
A huge thanks to Cyprien Noble, the @lucaspelkmans.bsky.social Lab, Marie-Hélène Verlhac @mhverlhac.bsky.social and Marie-Emilie Terret.
Reposted by Gallego Lab
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
July 7, 2025 at 2:05 PM
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
Reposted by Gallego Lab
With @ishier.bsky.social and @franbottanelli.bsky.social, we're helping @focalplane.bsky.social organize a #FocalPlanFeatures ... on membrane trafficking happening Sept. 25th! Keynote by Gillian Griffiths @yale.edu. Calling all ECRs: apply to give a talk focalplane.biologists.com/2025/07/14/f...
FocalPlane features... membrane trafficking - apply to give a talk - FocalPlane
FocalPlane features... membrane trafficking - apply to give a talk - News
focalplane.biologists.com
July 15, 2025 at 7:41 AM
With @ishier.bsky.social and @franbottanelli.bsky.social, we're helping @focalplane.bsky.social organize a #FocalPlanFeatures ... on membrane trafficking happening Sept. 25th! Keynote by Gillian Griffiths @yale.edu. Calling all ECRs: apply to give a talk focalplane.biologists.com/2025/07/14/f...
Reposted by Gallego Lab
The plasmids related to our mScarlet3-H are available on Addgene now. www.addgene.org/Zhifei_Fu/
August 16, 2025 at 2:47 AM
The plasmids related to our mScarlet3-H are available on Addgene now. www.addgene.org/Zhifei_Fu/
Reposted by Gallego Lab
How does evolution shape ancient cellular processes? Our new paper uncovers the mosaic evolution of conserved and diverging endocytic traits in fungi!
www.cell.com/current-biol...
www.cell.com/current-biol...
Mosaic evolution of clathrin-mediated endocytosis in fungi
Picco et al. take an evolutionary approach to study clathrin-mediated endocytosis
in a fungal clade and discover that the process is evolving in a mosaic fashion. The
early phase of endocytosis has sh...
www.cell.com
July 10, 2025 at 3:31 PM
How does evolution shape ancient cellular processes? Our new paper uncovers the mosaic evolution of conserved and diverging endocytic traits in fungi!
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Gallego Lab
Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio
meetings.embo.org/event/26-org...
meetings.embo.org/event/26-org...
Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
meetings.embo.org
July 4, 2025 at 3:50 PM
Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio
meetings.embo.org/event/26-org...
meetings.embo.org/event/26-org...
Reposted by Gallego Lab
Reposted by Gallego Lab
Reminder: the @globias.bsky.social 2025 symposium is happening Oct 26-31 in Kobe, Japan, and, on top of many other cool bioimage analysis events, several members of the napari core team will be leading a napari hackathon. 🧑💻👩💻👨💻 Registration deadline is Jun 15!
www.globias.org/activities/b...
www.globias.org/activities/b...
Bioimage Analysis Conference 2025 in Kobe
GloBIAS Bioimage Analysis Conference 2025
Oct 26, 2025 - Oct 31, 2025 | Kobe, Japan
Venue: RIKEN BDR, Kobe, Japan
Registration via Google Forms here:
https://tinyurl.com/3dtajhh6
General informatio...
www.globias.org
June 3, 2025 at 4:46 AM
Reminder: the @globias.bsky.social 2025 symposium is happening Oct 26-31 in Kobe, Japan, and, on top of many other cool bioimage analysis events, several members of the napari core team will be leading a napari hackathon. 🧑💻👩💻👨💻 Registration deadline is Jun 15!
www.globias.org/activities/b...
www.globias.org/activities/b...
In image analysis?? Then do not miss this conference!! We will be in Kobe🙌
Deadlines extended - you can still register for the GloBIAS conference! We have extended most deadlines. Please check our webpage: tinyurl.com/mr3kx5a5! Looking forward to welcoming you to Kobe, for training, developing and discussing a broad range of BIA topics!
May 16, 2025 at 9:08 AM
In image analysis?? Then do not miss this conference!! We will be in Kobe🙌
Reposted by Gallego Lab
Update on stable red FPs: mYonghong is out in
@naturemethods.bsky.social, now renamed mScarlet3-H (logical as it's mScarlet3 with the M163H point mutation like mScarlet-H):
www.nature.com/articles/s41...
I guess mScarlet3-S2 (with added M66Q) will be out soon too, should be renamed mScarlet3-HQ 😁
@naturemethods.bsky.social, now renamed mScarlet3-H (logical as it's mScarlet3 with the M163H point mutation like mScarlet-H):
www.nature.com/articles/s41...
I guess mScarlet3-S2 (with added M66Q) will be out soon too, should be renamed mScarlet3-HQ 😁
April 17, 2025 at 12:08 PM
Update on stable red FPs: mYonghong is out in
@naturemethods.bsky.social, now renamed mScarlet3-H (logical as it's mScarlet3 with the M163H point mutation like mScarlet-H):
www.nature.com/articles/s41...
I guess mScarlet3-S2 (with added M66Q) will be out soon too, should be renamed mScarlet3-HQ 😁
@naturemethods.bsky.social, now renamed mScarlet3-H (logical as it's mScarlet3 with the M163H point mutation like mScarlet-H):
www.nature.com/articles/s41...
I guess mScarlet3-S2 (with added M66Q) will be out soon too, should be renamed mScarlet3-HQ 😁
Reposted by Gallego Lab
El Departament de Medicina i Ciències de la Vida (MELIS) de la #UPFBarcelona, reconegut com a unitat d’excel·lència María de Maeztu per tercer cop, després d’haver obtingut ja aquesta acreditació el 2019 i el 2014 👏
@sdrecercaupf.bsky.social
https://f.mtr.cool/jgxbzkwsvj
@sdrecercaupf.bsky.social
https://f.mtr.cool/jgxbzkwsvj
April 17, 2025 at 11:11 AM
El Departament de Medicina i Ciències de la Vida (MELIS) de la #UPFBarcelona, reconegut com a unitat d’excel·lència María de Maeztu per tercer cop, després d’haver obtingut ja aquesta acreditació el 2019 i el 2014 👏
@sdrecercaupf.bsky.social
https://f.mtr.cool/jgxbzkwsvj
@sdrecercaupf.bsky.social
https://f.mtr.cool/jgxbzkwsvj
Reposted by Gallego Lab
I am recruiting a research assistant. Please send to anyone you know who is interested in gaining more lab experience in host:pathogen interactions of bacterial infections.
www.jobs.cam.ac.uk/job/50738/
www.jobs.cam.ac.uk/job/50738/
Research Assistant - Godlee Group (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant - Godlee Group (Fixed Term) in the Department of Biochemistry at the University of Cambridge.
www.jobs.cam.ac.uk
March 31, 2025 at 7:38 AM
I am recruiting a research assistant. Please send to anyone you know who is interested in gaining more lab experience in host:pathogen interactions of bacterial infections.
www.jobs.cam.ac.uk/job/50738/
www.jobs.cam.ac.uk/job/50738/
Please share🙌🤗
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
www.upf.edu
April 2, 2025 at 12:49 PM
Please share🙌🤗
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
Registration open! Do not miss this great workshop "When predictions meet experiments: The next challenges in structural biology"
Excellent program in the perfect season to enjoy Palermo, what else;-)
#EMBOStructuralBio #EMBOevents
Excellent program in the perfect season to enjoy Palermo, what else;-)
#EMBOStructuralBio #EMBOevents
Register now for EMBO Workshop "When predictions meet experiments: The next challenges in structural biology" in Palermo, Italy, 9 – 12 September 2025
Abstract submission & registration deadline: 1 July
meetings.embo.org/event/25-str...
#EMBOStructuralBio #EMBOevents 🧪
Abstract submission & registration deadline: 1 July
meetings.embo.org/event/25-str...
#EMBOStructuralBio #EMBOevents 🧪
When predictions meet experiments: the next challenges in structural biology
Building on the success of the 2022 EMBO Workshop “When Predictions Meet Experiments: The Future of Structure Determination”, this second edition continues the journey at the interface of computation…
meetings.embo.org
March 25, 2025 at 6:01 PM
Registration open! Do not miss this great workshop "When predictions meet experiments: The next challenges in structural biology"
Excellent program in the perfect season to enjoy Palermo, what else;-)
#EMBOStructuralBio #EMBOevents
Excellent program in the perfect season to enjoy Palermo, what else;-)
#EMBOStructuralBio #EMBOevents
Reposted by Gallego Lab
Together with @gallegolab.bsky.social we are organizing the next CATCAT morning on "Dynamics in biology, from molecules to tissues", with an amazing lineup of local and international speakers. If in Barcelona on May 26th, don't miss it, it's free! www.catcat-celltissuebiology.cat/event/9th-ca...
March 14, 2025 at 9:57 AM
Together with @gallegolab.bsky.social we are organizing the next CATCAT morning on "Dynamics in biology, from molecules to tissues", with an amazing lineup of local and international speakers. If in Barcelona on May 26th, don't miss it, it's free! www.catcat-celltissuebiology.cat/event/9th-ca...