Ryan Townley
@drtfromkc.bsky.social
Girl dad x 3 👸 | Dog dad x 2 🐶| Cognitive & Behavioral Neurologist 🧠| Program Director 🎬| Leading clinical trials in AD, DLB, and FTD. 👨🔬🔬Unraveling the mysteries of the mind, one axon at a time.
October is Lewy Body Awareness month.
Please see attached educational opportunity for both medical professionals and families this Saturday morning on Zoom:
Please see attached educational opportunity for both medical professionals and families this Saturday morning on Zoom:
October 8, 2025 at 1:39 PM
October is Lewy Body Awareness month.
Please see attached educational opportunity for both medical professionals and families this Saturday morning on Zoom:
Please see attached educational opportunity for both medical professionals and families this Saturday morning on Zoom:
Reposted by Ryan Townley
Smart! Raven loves winning Tic Tac Toe.
August 6, 2025 at 3:46 PM
Smart! Raven loves winning Tic Tac Toe.
Reposted by Ryan Townley
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system
erictopol.substack.com/p/our-braini...
erictopol.substack.com/p/our-braini...
August 4, 2025 at 9:09 PM
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system
erictopol.substack.com/p/our-braini...
erictopol.substack.com/p/our-braini...
Reposted by Ryan Townley
FIRST ON CNN: Dramatic lifestyle changes can fight early-stage Alzheimer’s, study says. Here’s how | CNN www.cnn.com/2025/07/...
FIRST ON CNN: Dramatic lifestyle changes can fight early-stage Alzheimer’s, study says. Here’s how | CNN
Adopting intensive lifestyle changes can slow or stop progression of early-stage Alzheimer’s disease, according to a new study.
www.cnn.com
July 30, 2025 at 12:51 PM
FIRST ON CNN: Dramatic lifestyle changes can fight early-stage Alzheimer’s, study says. Here’s how | CNN www.cnn.com/2025/07/...
Reposted by Ryan Townley
What's the optimal number of steps of physical activity this is associated with multiple (9) favorable outcomes?
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis
Although 10 000 steps per day can still be a viable target for those who are more
active, 7000 steps per day is associated with clinically meaningful improvements in
health outcomes and might be a mor...
thelancet.com
July 23, 2025 at 10:34 PM
What's the optimal number of steps of physical activity this is associated with multiple (9) favorable outcomes?
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...
Reposted by Ryan Townley
I seriously think the Social Internet is 21st century cigarettes. Complete with secondary smoke causing a lot of harm in nonusers.
June 22, 2025 at 2:48 PM
I seriously think the Social Internet is 21st century cigarettes. Complete with secondary smoke causing a lot of harm in nonusers.
This fits with my theories here of dementia being a multiple hit hypothesis and structural changes over a decade before lay the groundwork for brain failure in the setting of cognitive/systemic stressors.
June 19, 2025 at 1:19 PM
This fits with my theories here of dementia being a multiple hit hypothesis and structural changes over a decade before lay the groundwork for brain failure in the setting of cognitive/systemic stressors.
Amazing thread.
Trump has shown us on countless occasions that he has no shame.
It’s more troublesome that there are enough like minded individuals he has surrounded himself with to propagate this metastatic hate.
Trump has shown us on countless occasions that he has no shame.
It’s more troublesome that there are enough like minded individuals he has surrounded himself with to propagate this metastatic hate.
I'm sorry. I stopped typing and just listened. I'll post summaries as they're published.
But the end was that Judge Young went on to defend judicial independence and to underscore the perilous moment in American history where racial discrimination is tolerated.
He ends with "Have we no shame?"
But the end was that Judge Young went on to defend judicial independence and to underscore the perilous moment in American history where racial discrimination is tolerated.
He ends with "Have we no shame?"
June 16, 2025 at 9:58 PM
Amazing thread.
Trump has shown us on countless occasions that he has no shame.
It’s more troublesome that there are enough like minded individuals he has surrounded himself with to propagate this metastatic hate.
Trump has shown us on countless occasions that he has no shame.
It’s more troublesome that there are enough like minded individuals he has surrounded himself with to propagate this metastatic hate.
Reposted by Ryan Townley
“A society grows great when old men plant trees whose shade they know they shall never sit in.”
— Greek proverb
— Greek proverb
June 4, 2025 at 10:36 PM
“A society grows great when old men plant trees whose shade they know they shall never sit in.”
— Greek proverb
— Greek proverb
Timeline cleanser
This dog politely asked for a musician's drumstick in the middle of their performance. Always excited to find a fellow stick lover. 12/10
May 15, 2025 at 9:06 PM
Timeline cleanser
Reposted by Ryan Townley
Astrocytes have long been conceived as passive support player cells in the brain. But today @science.org (via 3 reports) they got a big upgrade for their active role in neuromodulation and control of brain function
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
May 15, 2025 at 6:49 PM
Astrocytes have long been conceived as passive support player cells in the brain. But today @science.org (via 3 reports) they got a big upgrade for their active role in neuromodulation and control of brain function
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Ryan Townley
Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4
Contrary to Clear, Verifiable Facts, Secretary Kennedy Continues to Repeat Harmful Myths About Alzheimer’s and Dementia Research
The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.
bit.ly
May 15, 2025 at 8:23 PM
Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4
Reposted by Ryan Townley
🔥 Most important paper I've read all year🔥
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
Biological markers and psychosocial factors predict chronic pain conditions - Nature Human Behaviour
Fillingim et al. show that biological and psychosocial factors jointly predict conditions associated with chronic pain.
www.nature.com
May 14, 2025 at 3:18 AM
🔥 Most important paper I've read all year🔥
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
Reposted by Ryan Townley
I just really need everybody to understand that everything that’s happening in and to the global economy now (and all the businesses and people in it) is the entirely predictable result of the intentional decisions of one guy who doesn’t understand how the global economy works.
May 10, 2025 at 2:53 PM
I just really need everybody to understand that everything that’s happening in and to the global economy now (and all the businesses and people in it) is the entirely predictable result of the intentional decisions of one guy who doesn’t understand how the global economy works.
Nightmare fuel
Weekly nightmares linked to cellular aging and early death. Strikingly, the effect size of frequent nightmares was greater than that of current smoking, obesity, and hypertension combined. www.medscape.com/viewarticle/...
Frequent Nightmares Linked to Faster Aging, Premature Death
Frequent distressing dreams are linked to faster biologic aging and an increased risk for premature death, independent of traditional risk factors, new research suggests.
www.medscape.com
May 10, 2025 at 1:52 PM
Nightmare fuel
Reposted by Ryan Townley
The gylmphatics of our brain, which clear waste products, interact with our immune system and are key to preserving brain health, modulating its aging process, and propensity for neurodegenerative diseases
A superb review @cp-immunity.bsky.social @jonykipnis.bsky.social
A superb review @cp-immunity.bsky.social @jonykipnis.bsky.social
May 4, 2025 at 3:39 PM
The gylmphatics of our brain, which clear waste products, interact with our immune system and are key to preserving brain health, modulating its aging process, and propensity for neurodegenerative diseases
A superb review @cp-immunity.bsky.social @jonykipnis.bsky.social
A superb review @cp-immunity.bsky.social @jonykipnis.bsky.social
Reposted by Ryan Townley
Catch probability? You wouldn’t believe me.
April 30, 2025 at 12:27 AM
Catch probability? You wouldn’t believe me.
Reposted by Ryan Townley
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
April 28, 2025 at 5:20 PM
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Reposted by Ryan Townley
Almost every line of this story would have been simply unbelievable a few months ago:
—Pioneering cancer researcher;
—*Arrested* at airport in Boston;
—Now indefinite ICE detention in Louisiana;
—"Crime": not declaring some frog-embryo samples for research.
Read it.
www.nbcnews.com/news/us-news...
—Pioneering cancer researcher;
—*Arrested* at airport in Boston;
—Now indefinite ICE detention in Louisiana;
—"Crime": not declaring some frog-embryo samples for research.
Read it.
www.nbcnews.com/news/us-news...
New images could change cancer diagnostics, but ICE detained the Harvard scientist who analyzes them
Without scientist Kseniia Petrova’s expertise, no one can fully unlock the data’s potential, putting crucial advancements in early cancer detection at risk.
www.nbcnews.com
April 22, 2025 at 1:32 AM
Almost every line of this story would have been simply unbelievable a few months ago:
—Pioneering cancer researcher;
—*Arrested* at airport in Boston;
—Now indefinite ICE detention in Louisiana;
—"Crime": not declaring some frog-embryo samples for research.
Read it.
www.nbcnews.com/news/us-news...
—Pioneering cancer researcher;
—*Arrested* at airport in Boston;
—Now indefinite ICE detention in Louisiana;
—"Crime": not declaring some frog-embryo samples for research.
Read it.
www.nbcnews.com/news/us-news...
Reposted by Ryan Townley
Personally, I think it should be front page news for at least a month if a sitting US President is using falsified evidence to try and deny due process to a man who has committed no crime, but that’s just me
April 19, 2025 at 11:35 PM
Personally, I think it should be front page news for at least a month if a sitting US President is using falsified evidence to try and deny due process to a man who has committed no crime, but that’s just me
Reposted by Ryan Townley
We've seen videos like this before, but usually when you see a tearful wife pleading with the kidnappers who have taken her husband, she's not talking to the U.S. president
Abrego Garcia's wife: "I will not stop fighting until I see my husband alive. Kilmar, if you can hear me, stay strong. God hasn't forgotten about you. Our children are asking when you will come home ... they miss their dad so much."
April 15, 2025 at 8:06 PM
We've seen videos like this before, but usually when you see a tearful wife pleading with the kidnappers who have taken her husband, she's not talking to the U.S. president
Reposted by Ryan Townley
“Inside that tiny speck is an entire architecture like an exquisite forest..." 🧠❤️
#neuroskyence
www.theguardian.com/science/2025...
#neuroskyence
www.theguardian.com/science/2025...
US scientists create most comprehensive circuit diagram of mammalian brain
The 3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring
www.theguardian.com
April 9, 2025 at 9:44 PM
“Inside that tiny speck is an entire architecture like an exquisite forest..." 🧠❤️
#neuroskyence
www.theguardian.com/science/2025...
#neuroskyence
www.theguardian.com/science/2025...
Lifestyle matters!!
KU has put together our LEAP (Lifestyle Enrichment for Alzheimer’s Prevention)
www.kumc.edu/research/alz...
KU has put together our LEAP (Lifestyle Enrichment for Alzheimer’s Prevention)
www.kumc.edu/research/alz...
April 8, 2025 at 6:49 PM
Lifestyle matters!!
KU has put together our LEAP (Lifestyle Enrichment for Alzheimer’s Prevention)
www.kumc.edu/research/alz...
KU has put together our LEAP (Lifestyle Enrichment for Alzheimer’s Prevention)
www.kumc.edu/research/alz...
Reposted by Ryan Townley
The Fourth Circuit is famously succinct. storage.courtlistener.com/recap/gov.us...
April 7, 2025 at 4:00 PM
The Fourth Circuit is famously succinct. storage.courtlistener.com/recap/gov.us...
