cryo-em.bsky.social
@cryo-em.bsky.social
Reposted by cryo-em.bsky.social
We are now offering the Thermo Scientific VitroEase™ Buffer Screening Kits & pre-formulated buffers/detergents - They provide a comprehensive screening strategy to identify optimal protein conditions for single particle #cryoem sample analysis - zurl.co/vJLLM
November 21, 2025 at 4:00 PM
We are now offering the Thermo Scientific VitroEase™ Buffer Screening Kits & pre-formulated buffers/detergents - They provide a comprehensive screening strategy to identify optimal protein conditions for single particle #cryoem sample analysis - zurl.co/vJLLM
Reposted by cryo-em.bsky.social
🚀 CryoCloud v2.16 is live!
This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows.
Full release notes → connect.cryocloud.io/release-note...
#CryoEM #StructuralBiology
This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows.
Full release notes → connect.cryocloud.io/release-note...
#CryoEM #StructuralBiology
November 21, 2025 at 4:19 PM
🚀 CryoCloud v2.16 is live!
This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows.
Full release notes → connect.cryocloud.io/release-note...
#CryoEM #StructuralBiology
This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows.
Full release notes → connect.cryocloud.io/release-note...
#CryoEM #StructuralBiology
Reposted by cryo-em.bsky.social
Happy to see our latest work online. Here we present a new method for microsecond time-resolved cryo-EM based on jet vitrification! Details in the 🧵 below... we hope you enjoy reading! (Hint, there's some fun videos...) #cryoEM #structuralbiology
Microsecond Time-Resolved Cryo-EM Based on Jet Vitrification https://www.biorxiv.org/content/10.1101/2025.11.21.689681v1
November 22, 2025 at 11:26 AM
Happy to see our latest work online. Here we present a new method for microsecond time-resolved cryo-EM based on jet vitrification! Details in the 🧵 below... we hope you enjoy reading! (Hint, there's some fun videos...) #cryoEM #structuralbiology
Reposted by cryo-em.bsky.social
Oh wow, this is 🤯 amazing: ~3-fold acceleration of running #relion on A100 GPUs for realistic single-particle refinement by the group of Guangwen Yang at @tsinghuauniversity.bsky.social
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
T2-RELION: Task Parallelism, Tensor Core Accelerated RELION for Cryo-EM 3D Reconstruction | Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis
dl.acm.org
November 21, 2025 at 12:32 PM
Oh wow, this is 🤯 amazing: ~3-fold acceleration of running #relion on A100 GPUs for realistic single-particle refinement by the group of Guangwen Yang at @tsinghuauniversity.bsky.social
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
.
What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍
dl.acm.org/doi/full/10....
Reposted by cryo-em.bsky.social
🚀 Hiring: Cryo-EM Application Scientist, Marketing!
Develop and deliver high-impact scientific marketing content, illustrate the value of new #CryoSPARC features and #cryoEM advances, and help scientists understand how our tools can help solve their problems.
structura.bio/careers/appl...
Develop and deliver high-impact scientific marketing content, illustrate the value of new #CryoSPARC features and #cryoEM advances, and help scientists understand how our tools can help solve their problems.
structura.bio/careers/appl...
Structura Bio | Structura Bio
structura.bio
November 20, 2025 at 9:00 PM
🚀 Hiring: Cryo-EM Application Scientist, Marketing!
Develop and deliver high-impact scientific marketing content, illustrate the value of new #CryoSPARC features and #cryoEM advances, and help scientists understand how our tools can help solve their problems.
structura.bio/careers/appl...
Develop and deliver high-impact scientific marketing content, illustrate the value of new #CryoSPARC features and #cryoEM advances, and help scientists understand how our tools can help solve their problems.
structura.bio/careers/appl...
Reposted by cryo-em.bsky.social
Watch the Tutorial: Introduction to Molecular Animation at PDB-101
Learn how to use ChimeraX to create simple animations that can enrich your presentations, websites, and social media
Learn how to use ChimeraX to create simple animations that can enrich your presentations, websites, and social media
PDB101: Tutorial: Introduction to Molecular Animation
PDB-101: Training, Outreach, and Education portal of RCSB PDB
pdb101.rcsb.org
November 19, 2025 at 5:12 PM
Watch the Tutorial: Introduction to Molecular Animation at PDB-101
Learn how to use ChimeraX to create simple animations that can enrich your presentations, websites, and social media
Learn how to use ChimeraX to create simple animations that can enrich your presentations, websites, and social media
Reposted by cryo-em.bsky.social
Today, at the Rice University Center for Nanoscale Imaging Sciences Conference, Prof. Steve Ludtke (BCM) presented impressive results of continuous-rotation cryo-ET, enabled by the ultra-fast counting of the DE Apollo camera. #teamtomo
November 18, 2025 at 10:38 PM
Today, at the Rice University Center for Nanoscale Imaging Sciences Conference, Prof. Steve Ludtke (BCM) presented impressive results of continuous-rotation cryo-ET, enabled by the ultra-fast counting of the DE Apollo camera. #teamtomo
Reposted by cryo-em.bsky.social
Join us November 18th to hear from Hui Wang, postdoc in the Hong Zhou lab at @uofcalifornia.bsky.social, Los Angeles, on TomoNet: Automatic Particle Picking of Flexible Lattice-Like Structures for CryoET.
Register here: buff.ly/QAMUkym
#SBGrid #StructuralBiology #Webinars
Register here: buff.ly/QAMUkym
#SBGrid #StructuralBiology #Webinars
Webinars
The SBGrid Consortium is an innovative global research computing group operated out of Harvard Medical School. SBGrid provides the global structural biology community with support for research…
buff.ly
November 17, 2025 at 5:05 PM
Join us November 18th to hear from Hui Wang, postdoc in the Hong Zhou lab at @uofcalifornia.bsky.social, Los Angeles, on TomoNet: Automatic Particle Picking of Flexible Lattice-Like Structures for CryoET.
Register here: buff.ly/QAMUkym
#SBGrid #StructuralBiology #Webinars
Register here: buff.ly/QAMUkym
#SBGrid #StructuralBiology #Webinars
Reposted by cryo-em.bsky.social
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
November 14, 2025 at 6:38 PM
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Reposted by cryo-em.bsky.social
New online: CryoAtom improves model building for cryo-EM
CryoAtom improves model building for cryo-EM
Nature Structural & Molecular Biology, Published online: 14 November 2025; doi:10.1038/s41594-025-01713-3Inspired by the advance in protein structure prediction, CryoAtom builds protein models directly from cryogenic electron microscopy maps, producing more complete models, reducing the resolution requirement and accelerating modeling.
go.nature.com
November 14, 2025 at 5:29 PM
New online: CryoAtom improves model building for cryo-EM
Reposted by cryo-em.bsky.social
Automated filtering of particle images in single particle cryoEM www.biorxiv.org/content/10.1101/2025.11.12.688030v1 #cryoem
November 14, 2025 at 9:31 AM
Automated filtering of particle images in single particle cryoEM www.biorxiv.org/content/10.1101/2025.11.12.688030v1 #cryoem
Reposted by cryo-em.bsky.social
Join our webinar on 20 Nov 10am/5pm CET on streamlining #cryo-ET and #SPA #Cryo-EM workflows. Learn about high-throughput lamella prep, optimized transfer techniques, efficient data acquisition and enhanced productivity and rapid quality assessment with our software. Register now: ter.li/e8l2gy
November 7, 2025 at 10:18 AM
Join our webinar on 20 Nov 10am/5pm CET on streamlining #cryo-ET and #SPA #Cryo-EM workflows. Learn about high-throughput lamella prep, optimized transfer techniques, efficient data acquisition and enhanced productivity and rapid quality assessment with our software. Register now: ter.li/e8l2gy
Reposted by cryo-em.bsky.social
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
CAHRA 2025: Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms
A community-wide data processing challenge for cryo-electron microscopy.
heterogeneity.notion.site
November 7, 2025 at 10:45 PM
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
Reposted by cryo-em.bsky.social
Lessons learned from a Kaggle challenge for particle picking in cryo-electron tomography www.biorxiv.org/content/10.1101/2025.11.03.686153v1 #cryoem
November 6, 2025 at 12:21 PM
Lessons learned from a Kaggle challenge for particle picking in cryo-electron tomography www.biorxiv.org/content/10.1101/2025.11.03.686153v1 #cryoem
Reposted by cryo-em.bsky.social
CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection pubmed.ncbi.nlm.nih.gov/41201048/ #cryoem
November 9, 2025 at 2:34 AM
CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection pubmed.ncbi.nlm.nih.gov/41201048/ #cryoem
Reposted by cryo-em.bsky.social
We are pleased to announce Doppio version 1.4! Available here www.ccpem.ac.uk/software/dow...
Downloads – CCP-EM
www.ccpem.ac.uk
November 4, 2025 at 5:38 PM
We are pleased to announce Doppio version 1.4! Available here www.ccpem.ac.uk/software/dow...
Reposted by cryo-em.bsky.social
I'm pleased to announce 🍦 Icecream 🍨 v0.3!
New features include:
* Training on multiple tomograms (same training time, with linear increase in RAM) 🚀
* Logging and plotting of the loss function 📉
* The --scale option is now called --eq-weight for clarity 😉
We'd love to hear your feedback! 🙏🏽
New features include:
* Training on multiple tomograms (same training time, with linear increase in RAM) 🚀
* Logging and plotting of the loss function 📉
* The --scale option is now called --eq-weight for clarity 😉
We'd love to hear your feedback! 🙏🏽
November 5, 2025 at 2:41 PM
I'm pleased to announce 🍦 Icecream 🍨 v0.3!
New features include:
* Training on multiple tomograms (same training time, with linear increase in RAM) 🚀
* Logging and plotting of the loss function 📉
* The --scale option is now called --eq-weight for clarity 😉
We'd love to hear your feedback! 🙏🏽
New features include:
* Training on multiple tomograms (same training time, with linear increase in RAM) 🚀
* Logging and plotting of the loss function 📉
* The --scale option is now called --eq-weight for clarity 😉
We'd love to hear your feedback! 🙏🏽
Reposted by cryo-em.bsky.social
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
Reposted by cryo-em.bsky.social
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
November 5, 2025 at 12:12 PM
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
Reposted by cryo-em.bsky.social
Workflow Using a Cryogenic Coincident Fluorescence, Electron, and Ion Beam Microscope for Targeted Milling of Cells pubmed.ncbi.nlm.nih.gov/41182991/ #cryoem
November 5, 2025 at 12:54 AM
Workflow Using a Cryogenic Coincident Fluorescence, Electron, and Ion Beam Microscope for Targeted Milling of Cells pubmed.ncbi.nlm.nih.gov/41182991/ #cryoem
Reposted by cryo-em.bsky.social
CryoWriter: A Robotic Solution for Improved Cryo-EM Grid Preparation www.biorxiv.org/content/10.1101/2025.11.01.686008v1 #cryoem
November 3, 2025 at 8:10 AM
CryoWriter: A Robotic Solution for Improved Cryo-EM Grid Preparation www.biorxiv.org/content/10.1101/2025.11.01.686008v1 #cryoem
Reposted by cryo-em.bsky.social
🔬 CECAM Workshop: “Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET Data”
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
CECAM - Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET data
www.cecam.org
November 1, 2025 at 9:47 AM
🔬 CECAM Workshop: “Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET Data”
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
Reposted by cryo-em.bsky.social
Interested in Biological Macromolecules?
IUCr2026 has you covered with NINETEEN symposia, including cryoEM/cryoET innovations; membrane proteins; protein design/engineering; drug discovery; 21st century structural enzymology; and more!
Join us in Calgary:
event.fourwaves.com/...
IUCr2026 has you covered with NINETEEN symposia, including cryoEM/cryoET innovations; membrane proteins; protein design/engineering; drug discovery; 21st century structural enzymology; and more!
Join us in Calgary:
event.fourwaves.com/...
October 28, 2025 at 3:31 PM
Interested in Biological Macromolecules?
IUCr2026 has you covered with NINETEEN symposia, including cryoEM/cryoET innovations; membrane proteins; protein design/engineering; drug discovery; 21st century structural enzymology; and more!
Join us in Calgary:
event.fourwaves.com/...
IUCr2026 has you covered with NINETEEN symposia, including cryoEM/cryoET innovations; membrane proteins; protein design/engineering; drug discovery; 21st century structural enzymology; and more!
Join us in Calgary:
event.fourwaves.com/...
Reposted by cryo-em.bsky.social
Registration is open for the Instruct Best Practices in Cryo-EM Workshop!
Taking place at the @humantechnopole.bsky.social in Milan, the workshop takes facility staff through latest developments in EM.
instruct-eric.org/events/best-... @thermofishersci.bsky.social #IMAGINE @embl.org
Taking place at the @humantechnopole.bsky.social in Milan, the workshop takes facility staff through latest developments in EM.
instruct-eric.org/events/best-... @thermofishersci.bsky.social #IMAGINE @embl.org
October 29, 2025 at 11:43 AM
Registration is open for the Instruct Best Practices in Cryo-EM Workshop!
Taking place at the @humantechnopole.bsky.social in Milan, the workshop takes facility staff through latest developments in EM.
instruct-eric.org/events/best-... @thermofishersci.bsky.social #IMAGINE @embl.org
Taking place at the @humantechnopole.bsky.social in Milan, the workshop takes facility staff through latest developments in EM.
instruct-eric.org/events/best-... @thermofishersci.bsky.social #IMAGINE @embl.org
Reposted by cryo-em.bsky.social
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...