Carles Foguet
cfoguet.bsky.social
Carles Foguet
@cfoguet.bsky.social
Català vivint a UK. Researcher at the BHF Cardiovascular Epidemiology Unit at Cambridge University. https://cfoguet.github.io/
Reposted by Carles Foguet
Emperor Palpatine

xkcd.com/3157/
October 22, 2025 at 8:07 PM
Reposted by Carles Foguet
Algorithmic fairness metrics have made big inroads in the AI/ML fields to investigate model bias. A clever PhD student (@clairecoffey.bsky.social) thought, why don't you see these methods applied to CVD risk prediction or polygenic risk scores? Enter our new preprint: www.medrxiv.org/content/10.1...
Current polygenic risk scores are unlikely to exacerbate unfairness in cardiovascular disease risk prediction
Background: Current cardiovascular disease (CVD) risk prediction models place many individuals in an intermediate risk category where clinical decision-making remains uncertain, highlighting a…
www.medrxiv.org
September 19, 2025 at 5:06 PM
Reposted by Carles Foguet
⏰ Last couple of days to apply to join my group @Cambridge as a postdoc and work on the environmental (un)sustainability of AI!

⏳ Closing September 16th.

✏️ Apply here: tinyurl.com/2ukkp8yx

Or learn more about what we do at www.lannelongue-group.org

Initial examples of research projects below 👇
Research Associate*/Research Assistant in Sustainability of AI (Fixed Term)
An exciting opportunity has arisen for a talented researcher to join our team as part of the Green Algorithms Initiative, one of the leading academic teams in the field of sustainable computing. The
www.cam.ac.uk
September 15, 2025 at 8:50 AM
Reposted by Carles Foguet
KASIE HUNT: Over the summer you said, “There’s no vaccine that’s safe and effective”. Do you still believe that?

RFK JR: “I never said that.”

KASIE HUNT: “Play the clip.”

RFK JR (clip): “There’s no vaccine that is safe and effective.” (March 2024)

ht: @cwebbonline.com
September 2, 2025 at 7:40 PM
Reposted by Carles Foguet
Yes, it was carefully hidden in the New England Journal of Medicine.

Pfizer/BioNTech vaccine (www.nejm.org/doi/pdf/10.1... )

1/2
September 1, 2025 at 4:08 PM
Reposted by Carles Foguet
An abbreviation (ABB) in a journal article (JA) or Grant Application (GA) is rarely worth the words it saves. Every ABB requires cognitive resources (CR) and at my age by the time I'm halfway through a JA or GA I no longer have the CR to remember what your ABB stood for.
August 15, 2025 at 9:39 AM
Reposted by Carles Foguet
Double the discovery, double the momentum 🚀

Europe doubles down on research competitiveness with a major boost to #HorizonEurope:

€95.5 billion foreseen for 2021-2027
💰💰💰💰💰💰💰💰💰

€175 billion proposed for 2028-2034
💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰
August 5, 2025 at 6:55 AM
Reposted by Carles Foguet
The Guardian's take on the new interim NASA administrator: "Duffy has no scientific background, but does have experience with transportation, as a former contestant on the MTV reality TV game show Road Rules, a Winnnebago driving contest."

the USA is soooooo fucked...
July 10, 2025 at 6:28 AM
Reposted by Carles Foguet
Summary of the significant evidence that the B-2s currently airborne are a strike package heading directly for Iran:

1. Immediate refuelling after departing from Whiteman Air Force Base indicates that the aircraft are carry close to their maximum payload.
June 21, 2025 at 3:19 PM
Reposted by Carles Foguet
We're working closely with our PredictDB colleagues to bring you an integrated resource for multi-omic predictors

We're happy to announce that PrediXcan GTExV8 expression predictors are now annotated and openly available via OmicsPred! www.omicspred.org

More info www.omicspred.org/publication/...
OmicsPred is an atlas of genetic scores for prediction of multi-omics data.
www.omicspred.org
June 16, 2025 at 12:24 PM
Reposted by Carles Foguet
Super excited to see beginning integration of PredictDB into OmicsPred!

We've annotated/deposited the GTExV8 gene expression predictors so they are now available alongside all the other multi-omic predictors at www.omicspred.org

More on its way... a wonderful collab with @hakyim.bsky.social & co!
June 16, 2025 at 10:33 AM
Reposted by Carles Foguet
📣 Latest from the lab: Performance of deep-learning-based approaches to improve polygenic scores www.nature.com/articles/s41...

Its thought deep learning will substantially improve PGS but the reality is MANY have tried but no/little gain has been seen so far. Here we report our negative results.
June 5, 2025 at 1:37 PM
Reposted by Carles Foguet
@hasanga.bsky.social from @mikeinouye.bsky.social / @cambridgebaker.bsky.social @cambridge-ceu.bsky.social sharing new results for local-ancestry effects on CAD risk loci. #ESHG2025
May 24, 2025 at 9:38 AM
Reposted by Carles Foguet
ICYMI: Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities www.nature.com/articles/s41...

Collaboration with @astra-zeneca.bsky.social throwing up very interesting targets including FAM3D (T2D), ITIH4 & EFEMP1 (CVD in those with T2D)
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities - Nature Communications
Here, the authors leveraged genetic and proteomic information from the UK Biobank and two randomized controlled trials to characterize how polygenic disease risk for T2D and related comorbidities pert...
www.nature.com
May 20, 2025 at 1:47 PM
Reposted by Carles Foguet
We are now on Bluesky!

Follow us to keep up to date with our research and find out what goes on at the Cardiovascular Epidemiology Unit in the @dphpc.bsky.social

#cardiovasculardisease #prevention #healthcare #bigdata #globalhealth #publichealth #riskfactors
May 19, 2025 at 3:00 PM
Reposted by Carles Foguet
Are you a new PhD interested in cardiovascular disease, big data, cohorts, or multi-omics? Join our Cardiovascular Epidemiology Unit at the University of Cambridge for a British Heart Foundation-funded postdoctoral position. Open to those not currently in the CVD field. 🔗: buff.ly/R7YJvfl
Research Assistant/Research Associate* in Cardiovascular Epidemiology (BHF Scholarship) (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/Research Associate* in Cardiovascular Epidemiology (BHF Scholarship) (Fixed Term) in the Department of Public Health and Primary Care, Cardiovascular Epidemiology Unit at the…
buff.ly
May 14, 2025 at 10:08 AM
Reposted by Carles Foguet
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!

These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.

Save and share the post!
May 13, 2025 at 7:55 PM
Reposted by Carles Foguet
📣 Psychological & behavioural considerations for integrating polygenic risk scores for disease into clinical practice www.nature.com/articles/s41...

Saskia Sanderson & I wrote a piece assessing the common concern that PRS may have psych/behavioural harms

tl;dr 👉 There's little/no evidence for this
May 12, 2025 at 3:49 PM
Reposted by Carles Foguet
📣 Interested in the environmental (un)sustainability of AI (and how to support positive change)? Or know someone who is? I have an open position for a postdoctoral researcher to join my group in Cambridge, UK 🌱

🚨Closing June 5th

www.jobs.cam.ac.uk/job/51255/

Topics below 👇

#AcademicSky #GreenSky
May 9, 2025 at 12:36 PM
Reposted by Carles Foguet
📣📣 Thrilled to see this cool work finally out in the wild! "Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology & prediction" www.nature.com/articles/s41...

Loads of cool findings including MR for alcohol usage -> increased variance in BC traits
May 7, 2025 at 7:21 PM
Reposted by Carles Foguet
Our new work testing nicotine, alcohol, and caffeine exposure across many cell types at once, including their modulation of eQTLs. Take a look!
1/n 🚨Very excited to share our recent work!🚨
To understand gene regulation across diverse environmental conditions and cellular contexts, we treated a broad array of human cell types with three environmental exposures in vitro.
www.biorxiv.org/content/10.1...
May 5, 2025 at 8:31 PM
Reposted by Carles Foguet
Absolutely brilliant news. It was so important that the govt organised British re-entry to Horizon: UK wins £500m in science grants from EU Horizon scheme after Brexit lockout
www.theguardian.com/science/2025...
UK wins £500m in science grants from EU Horizon scheme after Brexit lockout
Exclusive: British scientists ‘over the moon’ with re-entry to funding scheme after losing out for three years
www.theguardian.com
May 5, 2025 at 5:23 AM
Reposted by Carles Foguet
Big news for health data research and population diversity: The Mexico City Prospective Study data are now available securely to approved researchers worldwide. www.ndph.ox.ac.uk/news/latin-a...

Cohort description: www.ctsu.ox.ac.uk/research/pro...
Latin-American genetic data available securely to approved researchers worldwide/Datos genéticos latinoamericanos disponibles para investigadores de todo el mundo
www.ndph.ox.ac.uk
May 2, 2025 at 9:05 AM
Reposted by Carles Foguet
Cuts to #NIH funding don't just hurt scientists, but everyone who depends on new treatments, cures, & medical breakthroughs. Research can't thrive without strong, sustained support. Read more in this @60minutes.bsky.social segment featuring former NIH director Francis Collins: buff.ly/REjVWPc
Scientists fear Trump administration cuts to NIH could impact the health of Americans for generations
Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans' health.
buff.ly
April 29, 2025 at 8:02 PM
Reposted by Carles Foguet
A reminder for people looking for postdocs, our lab has an opening! www.jobs.cam.ac.uk/job/50966/ 👇

bsky.app/profile/mike...
📣📣 New postdoc in biomedical data science available in our lab!! www.jobs.cam.ac.uk/job/50966/

Flexible funding - many research areas in scope + ideas welcome

Check out our group www.inouyelab.org/home

And the awesome Cambridge research environment! @vpd-hlri.bsky.social @uniofcam.bsky.social
April 23, 2025 at 10:47 AM