Thibault Mayor
@cellsandprots.bsky.social
Prof of Biochemistry & Molecular Biology at @ubc and @msl Our team focuses on proteostasis and yeast cell biofactories
❤️ ubiquitin, chaperones & proteomics
💙 outdoor, repast, electro-rock & traveling 🇨🇭🇨🇦
https://mayor51.wixsite.com/mayorlab
❤️ ubiquitin, chaperones & proteomics
💙 outdoor, repast, electro-rock & traveling 🇨🇭🇨🇦
https://mayor51.wixsite.com/mayorlab
Pinned
Thibault Mayor
@cellsandprots.bsky.social
· Jan 10
Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published!
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
Reposted by Thibault Mayor
📢BMBDG Seminar!
Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar.
📷 November 27, 2025, 2:30 PM, LSC 3
Hope to see you there!
Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar.
📷 November 27, 2025, 2:30 PM, LSC 3
Hope to see you there!
November 13, 2025 at 4:43 PM
📢BMBDG Seminar!
Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar.
📷 November 27, 2025, 2:30 PM, LSC 3
Hope to see you there!
Join us November 27, 2025 for an in-person presentation by Dr. El Bachir Affar.
📷 November 27, 2025, 2:30 PM, LSC 3
Hope to see you there!
I survived the 2025 EMBO protein quality control meeting - it was amazing despite a defective projector on day 1, and epileptic crisis on day 2, a black out in day 3, and we all got a shaky wake up call ~6am on day 5 by an earthquake… never a dull moment but most importantly great science
May 24, 2025 at 4:35 PM
I survived the 2025 EMBO protein quality control meeting - it was amazing despite a defective projector on day 1, and epileptic crisis on day 2, a black out in day 3, and we all got a shaky wake up call ~6am on day 5 by an earthquake… never a dull moment but most importantly great science
We ran over 200 eggaggregation experiments for Science Rendezvous - a blast!
May 11, 2025 at 8:16 PM
We ran over 200 eggaggregation experiments for Science Rendezvous - a blast!
Reposted by Thibault Mayor
Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out!
meetings.cshl.edu/courses.aspx...
meetings.cshl.edu/courses.aspx...
April 2, 2025 at 3:45 PM
Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out!
meetings.cshl.edu/courses.aspx...
meetings.cshl.edu/courses.aspx...
Here’s a quick throwback to celebrate the last day of winter: curling with the lab!
March 20, 2025 at 9:28 PM
Here’s a quick throwback to celebrate the last day of winter: curling with the lab!
Some of you will recognize this - I am done with our CIHR application. Just in time to start teaching a big course section ✌️
March 4, 2025 at 4:23 PM
Some of you will recognize this - I am done with our CIHR application. Just in time to start teaching a big course section ✌️
Reposted by Thibault Mayor
Bioinformatics Job Opportunity
Research Associate / Staff Scientist
Vancouver Canada
Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis
tinyurl.com/bm4ptux3
Priority to Canadians
Please repost
Research Associate / Staff Scientist
Vancouver Canada
Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis
tinyurl.com/bm4ptux3
Priority to Canadians
Please repost
Research Associate
Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Wasserman Laboratory | Department of Medical Genetics | Faculty of Medicine (Wyeth Wasserman) Posting End Date Febr...
tinyurl.com
February 27, 2025 at 11:59 PM
Bioinformatics Job Opportunity
Research Associate / Staff Scientist
Vancouver Canada
Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis
tinyurl.com/bm4ptux3
Priority to Canadians
Please repost
Research Associate / Staff Scientist
Vancouver Canada
Join the Silent Genomes Project to provide an outstanding genetic variation database for Indigenous peoples of Canada to improve rare disease diagnosis
tinyurl.com/bm4ptux3
Priority to Canadians
Please repost
Reposted by Thibault Mayor
Job available for Full Professor Tier 1 Canada Research Chair (CRC) - Indigenous Health and Well-Being at the Faculty of Health Science, Simon Fraser University (RT 🙏🏼 please):
www.sfu.ca/vpacademic/a...
www.sfu.ca/vpacademic/a...
Canada Research Chair - Indigenous Health and Well-Being
www.sfu.ca
February 22, 2025 at 1:40 AM
Job available for Full Professor Tier 1 Canada Research Chair (CRC) - Indigenous Health and Well-Being at the Faculty of Health Science, Simon Fraser University (RT 🙏🏼 please):
www.sfu.ca/vpacademic/a...
www.sfu.ca/vpacademic/a...
I enjoyed both @cherisirois.bsky.social presentation and conversation about the publishing world and Cell Press today
February 7, 2025 at 12:49 AM
I enjoyed both @cherisirois.bsky.social presentation and conversation about the publishing world and Cell Press today
With the help of e@UBC our BMB and MSL postdocs organized this great 1/2 day Academia to Industry workshop with a focus on entrepreneurship today
January 28, 2025 at 2:15 AM
With the help of e@UBC our BMB and MSL postdocs organized this great 1/2 day Academia to Industry workshop with a focus on entrepreneurship today
Even though David Baker's presentation was online, it was rad and inspiring. I really enjoyed today's session on machine learning at the 2025 PepTalk & BioLogic Summit
January 15, 2025 at 12:52 AM
Even though David Baker's presentation was online, it was rad and inspiring. I really enjoyed today's session on machine learning at the 2025 PepTalk & BioLogic Summit
Reposted by Thibault Mayor
Calling early-career colleagues with stories of racism / sexism / microaggressions to share (anonymously or not) for an article someone I know is doing! Please send me a DM asap. They'd need to interview you tomorrow (Tues). It's important these stories are shared, so please do reach out!
January 14, 2025 at 2:41 AM
Calling early-career colleagues with stories of racism / sexism / microaggressions to share (anonymously or not) for an article someone I know is doing! Please send me a DM asap. They'd need to interview you tomorrow (Tues). It's important these stories are shared, so please do reach out!
Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published!
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
January 10, 2025 at 5:10 PM
Protein quality control is a tug-of-war between degradation machinery and chaperones that promote folding. Thrilled to see our latest manuscript is now published!
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
👇 Follow 🧵 for quick summary
journals.biologists.com/jcs/article-...
Reposted by Thibault Mayor
CONGRATS to @supportourscience.bsky.social, Dr. Kaitlin Kharas, @sarahlaframboise.bsky.social & @cdrobich.bsky.social who were named "Nature's 10", a list of people who shaped science in 2024. #SupportOurScience achieved amazing things. The advocacy continues! www.nature.com/articles/d41...
This PhD student helped to win a major pay hike for Canadian researchers
Kaitlin Kharas is part of Nature’s 10, a list of people who shaped science in 2024.
www.nature.com
December 10, 2024 at 1:38 AM
CONGRATS to @supportourscience.bsky.social, Dr. Kaitlin Kharas, @sarahlaframboise.bsky.social & @cdrobich.bsky.social who were named "Nature's 10", a list of people who shaped science in 2024. #SupportOurScience achieved amazing things. The advocacy continues! www.nature.com/articles/d41...
Reposted by Thibault Mayor
ICYMI: Finland downgrades a bunch of Frontiers and MDPI journals to level 0.
julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi/en/news/chan...
Changes to the classification
julkaisufoorumi.fi
December 16, 2024 at 4:03 PM
ICYMI: Finland downgrades a bunch of Frontiers and MDPI journals to level 0.
julkaisufoorumi.fi/en/news/chan...
julkaisufoorumi.fi/en/news/chan...
Failures in Science - I just received a negative decision on a grant proposal—my fifth in a row. It’s a though streak but not the first one, and I just wanted to share.
short 🧵👇
short 🧵👇
December 10, 2024 at 6:22 PM
Failures in Science - I just received a negative decision on a grant proposal—my fifth in a row. It’s a though streak but not the first one, and I just wanted to share.
short 🧵👇
short 🧵👇
Reposted by Thibault Mayor
Will U.S. government scientists soon face the “muzzling” their Canadian counterparts experienced under right-wing Prime Minister Stephen Harper?
David Shiffman spoke to several people whose work was affected by Harper’s regressive policies, and they have advice to help prepare for Trump 2.0. ⬇️
Advice for U.S. Government Scientists: Lessons Learned From the ‘Muzzling’ of Their Canadian Counterparts • The Revelator
The next four years will be awful for the science and conservation community. By learning from past experiences, we can minimize the damage.
therevelator.org
December 6, 2024 at 7:37 PM
Will U.S. government scientists soon face the “muzzling” their Canadian counterparts experienced under right-wing Prime Minister Stephen Harper?
David Shiffman spoke to several people whose work was affected by Harper’s regressive policies, and they have advice to help prepare for Trump 2.0. ⬇️
Reposted by Thibault Mayor
ubc.wd10.myworkdayjobs.com/en-US/ubcfac...
We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.
We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.
Research Associate
Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Johnson Laboratory | Department of Cellular and Physiological Sciences | Faculty of Medicine (James Johnson) Postin...
ubc.wd10.myworkdayjobs.com
December 4, 2024 at 8:05 PM
ubc.wd10.myworkdayjobs.com/en-US/ubcfac...
We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.
We are looking for an imaging master to run a very cool shared microscope - Raman label-free, 2-photon, FLIM, high-res, fast capture, thick live tissue, organoids, high-content screening. We are a dynamic and supportive and fun environment.
Reposted by Thibault Mayor
Earlier this year, I received news that fake peer reviews were allegedly being submitted impersonating me and approximately six others
I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again
www.science.org/content/arti...
I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again
www.science.org/content/arti...
‘It felt very icky’: This scientist’s name was used to write fake peer reviews
Elsevier retracts dozens of journal articles that were published based on “fictitious” reviews
www.science.org
December 3, 2024 at 9:24 AM
Earlier this year, I received news that fake peer reviews were allegedly being submitted impersonating me and approximately six others
I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again
www.science.org/content/arti...
I shared my story with Science to, hopefully, reduce the chance of this kind of breach happening again
www.science.org/content/arti...
Reposted by Thibault Mayor
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 3, 2024 at 7:05 AM
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Congrats to Dane Sands in our lab for his Zymeworks Fellowships Award in Advanced Protein Therapeutics
December 2, 2024 at 7:10 PM
Congrats to Dane Sands in our lab for his Zymeworks Fellowships Award in Advanced Protein Therapeutics
Great quick read and a reminder that we first need to admit and accept our ignorance—that's what makes science so fun!
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
December 1, 2024 at 3:59 PM
Great quick read and a reminder that we first need to admit and accept our ignorance—that's what makes science so fun!
Reposted by Thibault Mayor
SAVE THE DATE 🗓️Ubiquitin & Friends Symposium: 8-9 May 2025 in Vienna!
Registration will open🔜 Keep an eye out for the announcement 👀
✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting!
🔗 www.protein-degradation.org/symposium/
Registration will open🔜 Keep an eye out for the announcement 👀
✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting!
🔗 www.protein-degradation.org/symposium/
November 29, 2024 at 2:18 PM
SAVE THE DATE 🗓️Ubiquitin & Friends Symposium: 8-9 May 2025 in Vienna!
Registration will open🔜 Keep an eye out for the announcement 👀
✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting!
🔗 www.protein-degradation.org/symposium/
Registration will open🔜 Keep an eye out for the announcement 👀
✨guest speaker lineup👇🧵 +talks from abstracts! Great chance for #ECRs to meet with peers & experts in a friendly setting!
🔗 www.protein-degradation.org/symposium/
This is real cool study showing how ubiquitin can recruit and activate a protease to eliminate a (DNA cross linked) protein … independently of the proteasome
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability https://www.biorxiv.org/content/10.1101/2024.11.26.625192v1
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability https://www.biorxiv.org/content/10.1101/2024.11.26.625192v1
The DNA-dependent protease SPRTN maintains genome stability by degrading toxic DNA-protein crosslink
www.biorxiv.org
November 29, 2024 at 4:38 PM
This is real cool study showing how ubiquitin can recruit and activate a protease to eliminate a (DNA cross linked) protein … independently of the proteasome
Reposted by Thibault Mayor
🚀 Excited to announce that our Lab @UBC is recruiting!
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 xin.tang@msl.ubc.ca
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 xin.tang@msl.ubc.ca
November 28, 2024 at 7:49 PM
🚀 Excited to announce that our Lab @UBC is recruiting!
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 xin.tang@msl.ubc.ca
🌟 We're looking for passionate intern, graduate, and postdoc with strong coding/ML backgrounds to join us in advancing AI for single-cell biology & brain-computer interfaces.
🏔️ Vancouver awaits!
👉 tanglab.msl.ubc.ca
📧 xin.tang@msl.ubc.ca