Cameron Day
@cameron-echelon.bsky.social
Scientist, LNP Services - Echelon Biosciences
Here for Molecular Biology, RNA, Lipids, and any relevant spirited discussion.
Here for Molecular Biology, RNA, Lipids, and any relevant spirited discussion.
Reposted by Cameron Day
The November issue is live nature.com/nbt/volumes/...
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
November 12, 2025 at 7:03 PM
The November issue is live nature.com/nbt/volumes/...
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
On the cover, lipid nanoparticles targeting the lung, designed using neural networks. A method developed by Witten et al. identified two structures that efficiently delivered mRNA to ferret lungs go.nature.com/4fbj0VU
Reposted by Cameron Day
Incredible good news
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.co.uk
September 24, 2025 at 12:27 PM
Incredible good news
Reposted by Cameron Day
Vaccines save lives, pass it on.
Vaccines save lives, pass it on.
Vaccines save lives. Pass it on.
August 30, 2025 at 12:41 AM
Vaccines save lives, pass it on.
Reposted by Cameron Day
BREAKING: Big moment as CDC staff stage a mass walkout.
They have lined the street outside its HQ to greet and salute the four top officials who have resigned in protest at RFK Jr’s attack on the agency’s science base.
(🎥 AP)
They have lined the street outside its HQ to greet and salute the four top officials who have resigned in protest at RFK Jr’s attack on the agency’s science base.
(🎥 AP)
August 28, 2025 at 7:42 PM
BREAKING: Big moment as CDC staff stage a mass walkout.
They have lined the street outside its HQ to greet and salute the four top officials who have resigned in protest at RFK Jr’s attack on the agency’s science base.
(🎥 AP)
They have lined the street outside its HQ to greet and salute the four top officials who have resigned in protest at RFK Jr’s attack on the agency’s science base.
(🎥 AP)
Reposted by Cameron Day
#Pseudouridine #RNA avoids immune detection through impaired endolysosomal processing and TLR engagement: Cell www.cell.com/cell/fulltex...
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
Toll-like receptors (TLRs) 7 and 8 detect RNA degradation products to sense infection.
However, modified nucleosides common in self-RNA—most notably pseudouridine—evade
recognition. This study finds t...
www.cell.com
July 1, 2025 at 8:09 PM
#Pseudouridine #RNA avoids immune detection through impaired endolysosomal processing and TLR engagement: Cell www.cell.com/cell/fulltex...
Reposted by Cameron Day
#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
June 13, 2025 at 1:33 PM
#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
Reposted by Cameron Day
To be clear, COVID-19 vaccination - as well as other critical vaccinations - should be recommended for pregnant people.
Full stop.
Full stop.
May 27, 2025 at 8:16 PM
To be clear, COVID-19 vaccination - as well as other critical vaccinations - should be recommended for pregnant people.
Full stop.
Full stop.
Reposted by Cameron Day
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.
www.spencer.org/grant_types/...
www.spencer.org/grant_types/...
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
www.spencer.org
May 2, 2025 at 9:07 PM
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.
www.spencer.org/grant_types/...
www.spencer.org/grant_types/...
Reposted by Cameron Day
Everyone please read and act! 👇
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 9:00 PM
Everyone please read and act! 👇
Happy Friday. Nothing to see here 🤦♂️ #vaccineswork #supportscience #handsoff
www.whitehouse.gov/lab-leak-tru...
www.whitehouse.gov/lab-leak-tru...
Lab Leak: The True Origins of Covid-19
THE ORIGIN “The Proximal Origin of SARS-CoV-2” publication — which was used repeatedly by public health officials and the media to discredit the lab leak
www.whitehouse.gov
April 18, 2025 at 11:20 PM
Happy Friday. Nothing to see here 🤦♂️ #vaccineswork #supportscience #handsoff
www.whitehouse.gov/lab-leak-tru...
www.whitehouse.gov/lab-leak-tru...
Reposted by Cameron Day
A nonsensical threat to:
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
Exclusive: NIH officials have advised scientists to remove reference to mRNA vaccines from their grant applications, in expectation the Trump administration intends to abandon most research in the field.
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
March 17, 2025 at 11:01 AM
A nonsensical threat to:
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
One of the most important advances in biotechnology of our time, already being used to successfully treat refractory cancers, enable genome editing, develop vaccines for infectious diseases for which there are none, treat autoimmune diseases, and more.
Weird. It’s like we paid for a bunch of research and it did… stuff. Neat
#science #biosky #standupforscience #research
#science #biosky #standupforscience #research
In my 25 years since high school I’ve seen
1. HIV/AIDS go from death sentence to manageable with drugs
2. Cystic fibrosis go from pretty much an extended death sentence to manageable with drugs
3. Sickle cell go from a horrible disease to (almost maybe) cured by gene therapy
Simply incredible
1. HIV/AIDS go from death sentence to manageable with drugs
2. Cystic fibrosis go from pretty much an extended death sentence to manageable with drugs
3. Sickle cell go from a horrible disease to (almost maybe) cured by gene therapy
Simply incredible
March 15, 2025 at 1:38 PM
Weird. It’s like we paid for a bunch of research and it did… stuff. Neat
#science #biosky #standupforscience #research
#science #biosky #standupforscience #research
Reposted by Cameron Day
#PubMed has been down for some people and currently appears broken, or inaccessible. Smarter people than I can speculate on what's going on, but my worry is particular research being targeted for deletion from the database. All of us whose research can be found via PubMed must backup publications.
March 1, 2025 at 11:38 PM
#PubMed has been down for some people and currently appears broken, or inaccessible. Smarter people than I can speculate on what's going on, but my worry is particular research being targeted for deletion from the database. All of us whose research can be found via PubMed must backup publications.
February 26, 2025 at 4:15 PM
Glad to see this published. We saw an uptick in interest in some of these reagents after the #preprint hit. It’s a good study and an important potential addition to the #genetic #therapy toolbox
#lipids #LNP #lipidnanoparticles #DNA #inflammation
#lipids #LNP #lipidnanoparticles #DNA #inflammation
Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids - @pennmedicine.bsky.social go.nature.com/3EkClak
Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids - Nature Biotechnology
Lipid nanoparticles carrying plasmid DNA and an inflammation inhibitor enable longer transgene expression than mRNA nanoparticles.
go.nature.com
February 5, 2025 at 4:44 PM
Glad to see this published. We saw an uptick in interest in some of these reagents after the #preprint hit. It’s a good study and an important potential addition to the #genetic #therapy toolbox
#lipids #LNP #lipidnanoparticles #DNA #inflammation
#lipids #LNP #lipidnanoparticles #DNA #inflammation
To anyone in the #science community concerned about the #spending #freeze, a full list of potentially affected programs is available here: www.politico.com/news/2025/01...
This includes programs within HHS across various arms of #NIH
This includes programs within HHS across various arms of #NIH
Trump administration targets thousands of programs in funding freeze
A new memo from the Office of Management and Budget reveals the potential scope of the Trump administration's plans to freeze federal funding.
www.politico.com
January 29, 2025 at 4:14 PM
To anyone in the #science community concerned about the #spending #freeze, a full list of potentially affected programs is available here: www.politico.com/news/2025/01...
This includes programs within HHS across various arms of #NIH
This includes programs within HHS across various arms of #NIH
Day 1 - signs up for Bluesky to have non-political conversations about #science
Day 2 -
ALSO Day 1 - federal funding for #reaearch in the U.S. gets frozen for political reasons
#NIH #NSF #economy #innovation #nationalsecurity
Day 2 -
ALSO Day 1 - federal funding for #reaearch in the U.S. gets frozen for political reasons
#NIH #NSF #economy #innovation #nationalsecurity
January 28, 2025 at 4:03 PM
Day 1 - signs up for Bluesky to have non-political conversations about #science
Day 2 -
ALSO Day 1 - federal funding for #reaearch in the U.S. gets frozen for political reasons
#NIH #NSF #economy #innovation #nationalsecurity
Day 2 -
ALSO Day 1 - federal funding for #reaearch in the U.S. gets frozen for political reasons
#NIH #NSF #economy #innovation #nationalsecurity