Wendy McDowall-Cotlear
bicoidnanos.bsky.social
Wendy McDowall-Cotlear
@bicoidnanos.bsky.social
Reposted by Wendy McDowall-Cotlear
Nature research paper: Predatory aggression evolved through adaptations to noradrenergic circuits

go.nature.com/3NxFCrs
Predatory aggression evolved through adaptations to noradrenergic circuits - Nature
Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of complex behavioural traits.
go.nature.com
January 23, 2026 at 9:16 AM
Reposted by Wendy McDowall-Cotlear
Nature research paper: Ageing promotes microglial accumulation of slow-degrading synaptic proteins

go.nature.com/4jOgSHu
Ageing promotes microglial accumulation of slow-degrading synaptic proteins - Nature
Newly developed mouse models that enable cell-specific analyses of proteostasis dynamics across the lifespan of the mice reveal key aspects of neuronal proteostasis with ageing.
go.nature.com
January 23, 2026 at 1:34 PM
Reposted by Wendy McDowall-Cotlear
CRISPR delivery explained: Why editing DNA is easier than getting the editor to the right cells
CRISPR delivery explained: Why editing DNA is easier than getting the editor to the right cells
CRISPR has a reputation for being almost plug-and-play. Choose a target, design a guide RNA, and the Cas enzyme will cut where it is told. That is the elegant part. The awkward part is the body.
dlvr.it
January 18, 2026 at 4:19 PM
Reposted by Wendy McDowall-Cotlear
New #Stanford CRISPRkit makes gene-editing experiments affordable for classrooms at just $2 each! 🧬 Perfect hands-on learning for students using just a smartphone camera. #CRISPR

phys.org/news/2024-09-k…
New kit makes classroom CRISPR experiments affordable and accessible
CRISPR, the gene-editing technology, has been one of the major breakthroughs in biology in the last two decades. And while students learn about the capability to cut, paste, and alter genes, it's rare ...
phys.org
December 1, 2024 at 4:29 AM
Reposted by Wendy McDowall-Cotlear
I can taste the genetics of bread in beer
February 2, 2026 at 2:40 AM
This is really, really interesting!! Take a look.
A single-cell epigenomic atlas of human immune cells highlights cell-type-specific features associated with genetic or environmental exposures, according to a paper in Nature Genetics. go.nature.com/4taJRJT 🧬 🧪
February 2, 2026 at 4:53 PM
Reposted by Wendy McDowall-Cotlear
🙅 No, autism is not caused by measles vaccine or paracetamol.

Autism has primarily genetic causes. 200+ genes identified since 2003.

Recent study (Nature, Oct 2025) shows genetic profiles differ by age at diagnosis.

Facts matter ↘️

www.pasteur.fr/en/research-...

#Autism #Science
Three questions about autism: what are the symptoms? What are the causes? And why are so many people affected?
The Trump administration has falsely suggested, with no scientific basis, that autism is linked to measles vaccination and paracetamol. Leaving aside these highly criticized claims, what are the actua...
www.pasteur.fr
January 21, 2026 at 2:48 PM
Reposted by Wendy McDowall-Cotlear
Do all rich people have it from inbreeding? 🤔 Let's get CRISPR on it.
January 15, 2026 at 2:48 AM
Reposted by Wendy McDowall-Cotlear
Finally caught up with this fascinating paper from December, reporting evidence that the genesis of eukaryotes began way before the symbiotic event that created mitochondria. By the time that happened, these critters already had most of the genetic resources needed...
www.nature.com/articles/s41...
Dated gene duplications elucidate the evolutionary assembly of eukaryotes - Nature
Analysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...
www.nature.com
January 21, 2026 at 1:48 PM
Reposted by Wendy McDowall-Cotlear
New study results "highlight the importance of careful diagnostic evaluation in #Alzheimers patients, where co-existing synucleinopathy may otherwise go unrecognized"; Good performance of the seeding amplification assay across disease indications
link.springer.com/article/10.1...
January 10, 2026 at 11:52 AM