Bertrand Benazeraf
@bertrandbenazeraf.bsky.social
Developmental Biologist, Team Leader, Toulouse. Morphogenesis, Interdisciplinarity, Timelapse, Bird embryos 🐥 my positions, likes, and RT are personals.
Reposted by Bertrand Benazeraf
Excited to share a fantastic PhD opportunity combining interdisciplinary approaches with me, @alexgfletcher.bsky.social and @rorylcooper.bsky.social sky.social! Please share!
November 3, 2025 at 3:48 PM
Excited to share a fantastic PhD opportunity combining interdisciplinary approaches with me, @alexgfletcher.bsky.social and @rorylcooper.bsky.social sky.social! Please share!
Reposted by Bertrand Benazeraf
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
September 11, 2025 at 9:36 AM
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
And another great gut epithelium story from our cool neighbors !!!😎 @cbitoulouse.bsky.social
Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Robust pan-junctional reinforcement preserves the gut epithelial barrier under mechanical stress
Epithelia are specialized tissue barriers that safeguard the organism's internal milieu from the hostile external environment, a function critically dependent on intercellular junctions. In the colon,...
www.biorxiv.org
October 30, 2025 at 2:48 PM
And another great gut epithelium story from our cool neighbors !!!😎 @cbitoulouse.bsky.social
Reposted by Bertrand Benazeraf
Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Robust pan-junctional reinforcement preserves the gut epithelial barrier under mechanical stress
Epithelia are specialized tissue barriers that safeguard the organism's internal milieu from the hostile external environment, a function critically dependent on intercellular junctions. In the colon,...
www.biorxiv.org
October 8, 2025 at 9:52 PM
Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Reposted by Bertrand Benazeraf
Dear colleagues, positions at CNRS (and INRIA) will (in all probability) be announced this winter. By then it will however be too late to properly prepare an application. Recent PhDs, postdocs etc interested in such positions should get right now in contact with teams who would like to recruit them.
September 14, 2025 at 5:26 PM
Dear colleagues, positions at CNRS (and INRIA) will (in all probability) be announced this winter. By then it will however be too late to properly prepare an application. Recent PhDs, postdocs etc interested in such positions should get right now in contact with teams who would like to recruit them.
Reposted by Bertrand Benazeraf
Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
September 9, 2025 at 4:05 PM
Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
Reposted by Bertrand Benazeraf
#JobOffer
💼 Cell and Molecular Biology Research Engineer (M/F)
📆 November 17th
📍Institut Jacques Monod / @spinalorga.bsky.social
Apply on the CNRS job portal before September 29th 🔗 emploi.cnrs.fr/Offres/CDD/U...
💼 Cell and Molecular Biology Research Engineer (M/F)
📆 November 17th
📍Institut Jacques Monod / @spinalorga.bsky.social
Apply on the CNRS job portal before September 29th 🔗 emploi.cnrs.fr/Offres/CDD/U...
September 9, 2025 at 9:35 AM
#JobOffer
💼 Cell and Molecular Biology Research Engineer (M/F)
📆 November 17th
📍Institut Jacques Monod / @spinalorga.bsky.social
Apply on the CNRS job portal before September 29th 🔗 emploi.cnrs.fr/Offres/CDD/U...
💼 Cell and Molecular Biology Research Engineer (M/F)
📆 November 17th
📍Institut Jacques Monod / @spinalorga.bsky.social
Apply on the CNRS job portal before September 29th 🔗 emploi.cnrs.fr/Offres/CDD/U...
Reposted by Bertrand Benazeraf
Bird’s eye view, literally. 🐦👁️ Glowing quail embryo eye for #FluorescenceFriday, #DevBio 🧪🔬
August 29, 2025 at 6:04 AM
Bird’s eye view, literally. 🐦👁️ Glowing quail embryo eye for #FluorescenceFriday, #DevBio 🧪🔬
Reposted by Bertrand Benazeraf
Hi bsky!
Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!
w/ A. Delahaye & @bensteventon.bsky.social
shorturl.at/v01DO
Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!
w/ A. Delahaye & @bensteventon.bsky.social
shorturl.at/v01DO
August 7, 2025 at 3:01 PM
Hi bsky!
Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!
w/ A. Delahaye & @bensteventon.bsky.social
shorturl.at/v01DO
Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!
w/ A. Delahaye & @bensteventon.bsky.social
shorturl.at/v01DO
Reposted by Bertrand Benazeraf
(1/10)
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
An active torque dipole across tissue layers drives avian left-right symmetry breaking
Unlike in mice, frogs, and fish, left-right (L/R) body axis formation in avian embryos does not arise from the chiral beat of cilia. Instead, a counter-clockwise tissue rotation around Hensen′ node, t...
doi.org
July 20, 2025 at 1:42 PM
(1/10)
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
Reposted by Bertrand Benazeraf
What started with many quail eggs and put me on stage in a chicken suit has now resulted in a preprint www.biorxiv.org/content/10.1...
Microsurgery with human eye-lashes, laser ablations, great analysis and insightful theory from @neipel.bsky.social told us more about avian L/R symmetry breaking.
Microsurgery with human eye-lashes, laser ablations, great analysis and insightful theory from @neipel.bsky.social told us more about avian L/R symmetry breaking.
July 21, 2025 at 1:42 PM
What started with many quail eggs and put me on stage in a chicken suit has now resulted in a preprint www.biorxiv.org/content/10.1...
Microsurgery with human eye-lashes, laser ablations, great analysis and insightful theory from @neipel.bsky.social told us more about avian L/R symmetry breaking.
Microsurgery with human eye-lashes, laser ablations, great analysis and insightful theory from @neipel.bsky.social told us more about avian L/R symmetry breaking.
Reposted by Bertrand Benazeraf
Two new preprints from the @arjunraj.bsky.social on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
July 15, 2025 at 1:28 PM
Two new preprints from the @arjunraj.bsky.social on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
Reposted by Bertrand Benazeraf
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
tinyurl.com
July 11, 2025 at 5:22 PM
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment.
tinyurl.com/mr3he6bx
tinyurl.com/mr3he6bx
Reposted by Bertrand Benazeraf
12th Avian Model Systems Meeting bit.ly/3ZBw2qS @stowersinstitute.bsky.social. We will be joined by Marianne Bronner, Olivier Pourquié, Megan Davey, Julie Elie, @jeromegros.bsky.social, Carols Lois, Peter Lwigale, Alan Rodrigues, Marcos Simoes-Costa, @melaniedwhite.bsky.social and YOU!
Research Organisms in Flight: Revealing the Roots of Vertebrate Form…
Organized by Tatjana Sauka-Spengler, Ph.D., and Ruth Williams, Ph.D.
bit.ly
July 11, 2025 at 10:33 AM
12th Avian Model Systems Meeting bit.ly/3ZBw2qS @stowersinstitute.bsky.social. We will be joined by Marianne Bronner, Olivier Pourquié, Megan Davey, Julie Elie, @jeromegros.bsky.social, Carols Lois, Peter Lwigale, Alan Rodrigues, Marcos Simoes-Costa, @melaniedwhite.bsky.social and YOU!
Reposted by Bertrand Benazeraf
🇫🇷 Nous recrutons un IE en biologie cellulaire, sur un modèle d'étude fascinant : le blob ! N'hésitez pas à partager !
🇬🇧 We are recruiting a research engineer in cell biology, working on an exciting model: the blob! Feel free to share!
👉 emploi.cnrs.fr/Offres/CDD/U...
🇬🇧 We are recruiting a research engineer in cell biology, working on an exciting model: the blob! Feel free to share!
👉 emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Ingénieur d'étude (H/F) en biologie cellulaire, modèle d'étude : Myxomycètes (blob)
emploi.cnrs.fr
July 1, 2025 at 8:12 AM
🇫🇷 Nous recrutons un IE en biologie cellulaire, sur un modèle d'étude fascinant : le blob ! N'hésitez pas à partager !
🇬🇧 We are recruiting a research engineer in cell biology, working on an exciting model: the blob! Feel free to share!
👉 emploi.cnrs.fr/Offres/CDD/U...
🇬🇧 We are recruiting a research engineer in cell biology, working on an exciting model: the blob! Feel free to share!
👉 emploi.cnrs.fr/Offres/CDD/U...
Reposted by Bertrand Benazeraf
Enjoying great science and stunning alpine views at the GRC on Cell Contact & Adhesion in Les Diablerets 🇨🇭⛰️ Proud of our PhD students Dhriti and Vishnu for their terrific work - posters and talks full of exciting insights! #CellContactAndAdhesionGRC #CellBiology #PhDLife #LesDiablerets
June 10, 2025 at 9:32 PM
Enjoying great science and stunning alpine views at the GRC on Cell Contact & Adhesion in Les Diablerets 🇨🇭⛰️ Proud of our PhD students Dhriti and Vishnu for their terrific work - posters and talks full of exciting insights! #CellContactAndAdhesionGRC #CellBiology #PhDLife #LesDiablerets
Great use of the transgenic quail model to answer very basic and important question in developmental biology !
🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction
In birds and mammals, the formation of the primitive streak, the hallmark of the primary axis and site of gastrulation, is thought to occur when an anterior displacement of the hypoblast (visceral end...
doi.org
May 22, 2025 at 4:38 PM
Great use of the transgenic quail model to answer very basic and important question in developmental biology !
Reposted by Bertrand Benazeraf
🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction
In birds and mammals, the formation of the primitive streak, the hallmark of the primary axis and site of gastrulation, is thought to occur when an anterior displacement of the hypoblast (visceral end...
doi.org
May 19, 2025 at 8:59 AM
🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Great work from Arthur Michaut again ! Very cool study on biophysical properties of the very young avian embryo. Congrats to Arthur, and to the teams of Francis and Jérôme !
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
www.biorxiv.org
May 12, 2025 at 7:32 PM
Great work from Arthur Michaut again ! Very cool study on biophysical properties of the very young avian embryo. Congrats to Arthur, and to the teams of Francis and Jérôme !
Reposted by Bertrand Benazeraf
This time-lapse captures 17 hours of axonal growth from a chicken dorsal root ganglion explant, visualized through the actin cytoskeleton using live confocal imaging.
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉
🧪
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉
🧪
April 30, 2025 at 7:16 AM
This time-lapse captures 17 hours of axonal growth from a chicken dorsal root ganglion explant, visualized through the actin cytoskeleton using live confocal imaging.
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉
🧪
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉
🧪
Reposted by Bertrand Benazeraf
#JobOffer
💼 Ingénieur d’étude (H/F) en cellules souches et biologie cellulaire
📍 @spinalorga.bsky.social Lab
📅 1e juillet 2025
🔗 emploi.cnrs.fr/Offres/CDD/U...
Candidatez avant le 15 mai 2025
💼 Ingénieur d’étude (H/F) en cellules souches et biologie cellulaire
📍 @spinalorga.bsky.social Lab
📅 1e juillet 2025
🔗 emploi.cnrs.fr/Offres/CDD/U...
Candidatez avant le 15 mai 2025
April 28, 2025 at 9:29 AM
#JobOffer
💼 Ingénieur d’étude (H/F) en cellules souches et biologie cellulaire
📍 @spinalorga.bsky.social Lab
📅 1e juillet 2025
🔗 emploi.cnrs.fr/Offres/CDD/U...
Candidatez avant le 15 mai 2025
💼 Ingénieur d’étude (H/F) en cellules souches et biologie cellulaire
📍 @spinalorga.bsky.social Lab
📅 1e juillet 2025
🔗 emploi.cnrs.fr/Offres/CDD/U...
Candidatez avant le 15 mai 2025
Reposted by Bertrand Benazeraf
We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social
Tissue spreading couples gastrulation through extracellular matrix remodelling in early avian embryos https://www.biorxiv.org/content/10.1101/2025.04.06.647388v1
April 10, 2025 at 8:39 AM
We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social
Is our gut epithelium a little cracked ? Turns out—yes🤯 , and especially around goblet cells! Check out the new preprint from our very talented neighbors @cbitoulouse.bsky.social👇
🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)
April 7, 2025 at 7:18 AM
Is our gut epithelium a little cracked ? Turns out—yes🤯 , and especially around goblet cells! Check out the new preprint from our very talented neighbors @cbitoulouse.bsky.social👇
Reposted by Bertrand Benazeraf
We’re looking for PhD students to join the lab! 🧫🧑🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
PhD Program
Empowering Curious Researchers at the Vienna BioCenter PhD Program
Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...
training.vbc.ac.at
April 1, 2025 at 1:00 PM
We’re looking for PhD students to join the lab! 🧫🧑🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
Reposted by Bertrand Benazeraf
Are postdocs the rarest species, or is it just me? We have two funded positions—apply now and join us on these exciting projects! #zebrafish #zebrafishcareers #iPSC #devbio #regeneration
March 31, 2025 at 7:37 PM
Are postdocs the rarest species, or is it just me? We have two funded positions—apply now and join us on these exciting projects! #zebrafish #zebrafishcareers #iPSC #devbio #regeneration