Lakshmi Balasubramaniam
@lakshmib02.bsky.social
Herchel Smith/ EMBO Postdoctoral fellow at the Gurdon Institute working on mechanics and embryogenesis at Xiong lab. PhD @Ladoux MegeLab, Paris. Cell migration, adhesion and biophysics aficionado.
Pinned
Tissue spreading couples gastrulation through extracellular matrix remodelling in early avian embryos https://www.biorxiv.org/content/10.1101/2025.04.06.647388v1
We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social
Reposted by Lakshmi Balasubramaniam
🚨Reminder that this is happening on Monday afternoon🚨. Do join us in person if you are in the Cambridge area. The talk will be followed by drinks and nibbles🍵🍷🍪
🚨TLM Seminar Series in collaboration with @cammorphoseries.bsky.social will host @pflenne.bsky.social from IBDM for a hybrid seminar on Monday 20th October at 14:30 UK Time🚨Sign up to our mailing list for a zoom link lists.cam.ac.uk/sympa/subscr...
October 17, 2025 at 9:29 AM
🚨Reminder that this is happening on Monday afternoon🚨. Do join us in person if you are in the Cambridge area. The talk will be followed by drinks and nibbles🍵🍷🍪
Do sign up to this amazing opportunity to present your interdisciplinary work to a diverse audience all across the world ✍️
Thank you to everyone who has supported TLM talks. We will be back in Ocotber with some new exciting talks. We have plans to incorporate short talks by students and postdocs, fill out this form to express your interest forms.gle/34vMwQNVGnvm....
Have a nice summer 🌅
Have a nice summer 🌅
Early Career Speaking List - Theory of Living Matter
Sign up to be considered as an Early Career Speaker at our upcoming events! Selected participants will have the opportunity to present their work and network with professionals in the field.
Importa...
forms.gle
July 25, 2025 at 5:30 PM
Do sign up to this amazing opportunity to present your interdisciplinary work to a diverse audience all across the world ✍️
Reposted by Lakshmi Balasubramaniam
(1/10)
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
An active torque dipole across tissue layers drives avian left-right symmetry breaking
Unlike in mice, frogs, and fish, left-right (L/R) body axis formation in avian embryos does not arise from the chiral beat of cilia. Instead, a counter-clockwise tissue rotation around Hensen′ node, t...
doi.org
July 20, 2025 at 1:42 PM
(1/10)
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
I am excited to finally share our work on avian left/right symmetry breaking with you. We reveal a tissue-scale active torque dipole generated at the Hensen’s node, thanks to crazy experiments by Julia @juliapfanzelter.bsky.social and some analysis by me.
doi.org/10.1101/2025...
Had a great time meeting other EMBO fellows and discussing the ups and downs being a postdoc. It was nice to walk away inspired from all the conversations and training sessions. Thanks @embo.org for bringing us all together
119 EMBO Fellows from 30+ countries attended the EMBO Fellows’ Meeting in Heidelberg, DE from 27 June–1 July. #Research was shared and connections formed – an incredible opportunity for #networking and #collaboration. Thank you to all who joined and were part of this vibrant community! 🧪
July 5, 2025 at 8:13 AM
Had a great time meeting other EMBO fellows and discussing the ups and downs being a postdoc. It was nice to walk away inspired from all the conversations and training sessions. Thanks @embo.org for bringing us all together
Join us online on Wednesday as part of Developments online webinar to hear about early development
Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
July 5, 2025 at 8:08 AM
Join us online on Wednesday as part of Developments online webinar to hear about early development
Reposted by Lakshmi Balasubramaniam
Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social.
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
June 23, 2025 at 8:26 AM
Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social.
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
📅Wed 9 July 15:00BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...
#DevBio @dev-journal.bsky.social
Reposted by Lakshmi Balasubramaniam
🚨Our next seminar on, Mon 16/05 | 14:30 UK - Hybrid Seminar in collaboration with @cammorphoseries.bsky.social at @slcuplants.bsky.social we have Chii Jou Chan from @mbisg.bsky.social Come join us in person if you are in Cambridge🚨📝for the zoom link: lists.cam.ac.uk/sympa/subscr...
May 30, 2025 at 2:24 PM
🚨Our next seminar on, Mon 16/05 | 14:30 UK - Hybrid Seminar in collaboration with @cammorphoseries.bsky.social at @slcuplants.bsky.social we have Chii Jou Chan from @mbisg.bsky.social Come join us in person if you are in Cambridge🚨📝for the zoom link: lists.cam.ac.uk/sympa/subscr...
Reposted by Lakshmi Balasubramaniam
🚨Next week, Wed 30/04 | 16:00 UK - Online Seminar🚨
"Learning the emergent order of living matter from bacteria" by Prof Yilin Wu from The Chinese University of Hong Kong.
To attend online please register to our 📧 for the zoom link: lists.cam.ac.uk/sympa/subscr...
"Learning the emergent order of living matter from bacteria" by Prof Yilin Wu from The Chinese University of Hong Kong.
To attend online please register to our 📧 for the zoom link: lists.cam.ac.uk/sympa/subscr...
April 24, 2025 at 4:42 PM
🚨Next week, Wed 30/04 | 16:00 UK - Online Seminar🚨
"Learning the emergent order of living matter from bacteria" by Prof Yilin Wu from The Chinese University of Hong Kong.
To attend online please register to our 📧 for the zoom link: lists.cam.ac.uk/sympa/subscr...
"Learning the emergent order of living matter from bacteria" by Prof Yilin Wu from The Chinese University of Hong Kong.
To attend online please register to our 📧 for the zoom link: lists.cam.ac.uk/sympa/subscr...
Reposted by Lakshmi Balasubramaniam
📢 Exciting news!!
🌟We have a stellar line up of speakers this Easter Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
🌟We have a stellar line up of speakers this Easter Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
April 10, 2025 at 1:30 PM
📢 Exciting news!!
🌟We have a stellar line up of speakers this Easter Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
🌟We have a stellar line up of speakers this Easter Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social
Tissue spreading couples gastrulation through extracellular matrix remodelling in early avian embryos https://www.biorxiv.org/content/10.1101/2025.04.06.647388v1
April 10, 2025 at 8:39 AM
We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social
Reposted by Lakshmi Balasubramaniam
Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
March 14, 2025 at 12:10 PM
Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
Reposted by Lakshmi Balasubramaniam
We're looking forward to welcoming @lakshmib02.bsky.social to our next CDMB seminar on 20 March, talking about "Extraembryonic tissue as a tool to study collective migration and multilayered tissue formation".
#UEAScience
#UEAScience
March 13, 2025 at 3:56 PM
We're looking forward to welcoming @lakshmib02.bsky.social to our next CDMB seminar on 20 March, talking about "Extraembryonic tissue as a tool to study collective migration and multilayered tissue formation".
#UEAScience
#UEAScience
Reposted by Lakshmi Balasubramaniam
What do star fish, snowflakes, and even cells have in common?
I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics
I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics
March 1, 2025 at 7:02 AM
What do star fish, snowflakes, and even cells have in common?
I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics
I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics
Reposted by Lakshmi Balasubramaniam
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
January 29, 2025 at 11:01 PM
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
www.biorxiv.org/content/10.1...
Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris
Any 3D systems?👇
Reposted by Lakshmi Balasubramaniam
🚨Next week, Wed 29/01 | 16:00 UK - Online Seminar🚨
"Patterning, waves and synchronization in cilia arrays" by Dr. Guillermina Rochelle Ramirez-San-Juan. Please repost & to attend online please register to our 📧for the zoom link: lists.cam.ac.uk/sympa/subscr...
#cilia #livingmatter #biophysics
"Patterning, waves and synchronization in cilia arrays" by Dr. Guillermina Rochelle Ramirez-San-Juan. Please repost & to attend online please register to our 📧for the zoom link: lists.cam.ac.uk/sympa/subscr...
#cilia #livingmatter #biophysics
January 22, 2025 at 11:18 AM
🚨Next week, Wed 29/01 | 16:00 UK - Online Seminar🚨
"Patterning, waves and synchronization in cilia arrays" by Dr. Guillermina Rochelle Ramirez-San-Juan. Please repost & to attend online please register to our 📧for the zoom link: lists.cam.ac.uk/sympa/subscr...
#cilia #livingmatter #biophysics
"Patterning, waves and synchronization in cilia arrays" by Dr. Guillermina Rochelle Ramirez-San-Juan. Please repost & to attend online please register to our 📧for the zoom link: lists.cam.ac.uk/sympa/subscr...
#cilia #livingmatter #biophysics
Reposted by Lakshmi Balasubramaniam
📢 Exciting news!!
🌟We have a stellar line up of speakers this Lent Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
🌟We have a stellar line up of speakers this Lent Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
January 13, 2025 at 5:23 PM
📢 Exciting news!!
🌟We have a stellar line up of speakers this Lent Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
🌟We have a stellar line up of speakers this Lent Term. Join us for online and hybrid talks that you won't want to miss.
✉️Subscribe to attend our online sessions: lists.cam.ac.uk/sympa/subscr...
Don’t forget to follow us for more details and online links!
Reposted by Lakshmi Balasubramaniam
✍️ L'équipe Ladoux/Mege a publié un nouvel article dans @naturephysics.bsky.social
📃"Dynamic forces shape the survival fate of eliminated cells"
🔗https://www.nature.com/articles/s41567-024-02716-5
Article relayé dans @cnrsbiologie.bsky.social ➡️ www.insb.cnrs.fr/fr/cnrsinfo/...
📃"Dynamic forces shape the survival fate of eliminated cells"
🔗https://www.nature.com/articles/s41567-024-02716-5
Article relayé dans @cnrsbiologie.bsky.social ➡️ www.insb.cnrs.fr/fr/cnrsinfo/...
January 14, 2025 at 9:25 AM
✍️ L'équipe Ladoux/Mege a publié un nouvel article dans @naturephysics.bsky.social
📃"Dynamic forces shape the survival fate of eliminated cells"
🔗https://www.nature.com/articles/s41567-024-02716-5
Article relayé dans @cnrsbiologie.bsky.social ➡️ www.insb.cnrs.fr/fr/cnrsinfo/...
📃"Dynamic forces shape the survival fate of eliminated cells"
🔗https://www.nature.com/articles/s41567-024-02716-5
Article relayé dans @cnrsbiologie.bsky.social ➡️ www.insb.cnrs.fr/fr/cnrsinfo/...
Reposted by Lakshmi Balasubramaniam
Published today! #Biophysics #Physics #Science
It turns out that the forces applied to cells as they are ejected from a tissue affects whether those cells 'live' or 'die'.
www.nature.com/articles/s41...
It turns out that the forces applied to cells as they are ejected from a tissue affects whether those cells 'live' or 'die'.
www.nature.com/articles/s41...
Dynamic forces shape the survival fate of eliminated cells - Nature Physics
Tissues eliminate unwanted cells through cell extrusion, but the factors determining whether these extuded cells live or die are not fully understood. Now force transmission across adherens junctions ...
www.nature.com
January 8, 2025 at 2:48 PM
Published today! #Biophysics #Physics #Science
It turns out that the forces applied to cells as they are ejected from a tissue affects whether those cells 'live' or 'die'.
www.nature.com/articles/s41...
It turns out that the forces applied to cells as they are ejected from a tissue affects whether those cells 'live' or 'die'.
www.nature.com/articles/s41...
Reposted by Lakshmi Balasubramaniam
Happy to share our new publication in @naturephysics.bsky.social on life and death of eliminated cells! Great collaboration between our CAM team and Doostmohammadi's. Special congrats @lakshmib02.bsky.social and Siavash Monfared! 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 8, 2025 at 11:33 AM
Happy to share our new publication in @naturephysics.bsky.social on life and death of eliminated cells! Great collaboration between our CAM team and Doostmohammadi's. Special congrats @lakshmib02.bsky.social and Siavash Monfared! 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Lakshmi Balasubramaniam
E-cad depletion promotes live extrusion and a shift toward basal extrusion in 2D MDCK culture on collagen and cyst
www.nature.com/articles/s41...
most likely through higher resistance to apoptosis and change faster dissipation of compressive stress.
www.nature.com/articles/s41...
most likely through higher resistance to apoptosis and change faster dissipation of compressive stress.
Dynamic forces shape the survival fate of eliminated cells - Nature Physics
Tissues eliminate unwanted cells through cell extrusion, but the factors determining whether these extuded cells live or die are not fully understood. Now force transmission across adherens junctions ...
www.nature.com
January 8, 2025 at 11:25 AM
E-cad depletion promotes live extrusion and a shift toward basal extrusion in 2D MDCK culture on collagen and cyst
www.nature.com/articles/s41...
most likely through higher resistance to apoptosis and change faster dissipation of compressive stress.
www.nature.com/articles/s41...
most likely through higher resistance to apoptosis and change faster dissipation of compressive stress.
Starting the new year with the last chapter of my PhD finally published on how physical forces and neighbour interaction regulate extrusion in @bladoux.bsky.social @rmmege.bsky.social in collaboration with Doostmohammadi group. Details below:https://www.nature.com/articles/s41567-024-02716-5
January 8, 2025 at 10:55 AM
Starting the new year with the last chapter of my PhD finally published on how physical forces and neighbour interaction regulate extrusion in @bladoux.bsky.social @rmmege.bsky.social in collaboration with Doostmohammadi group. Details below:https://www.nature.com/articles/s41567-024-02716-5
Reposted by Lakshmi Balasubramaniam
🚨Next week, Wed 04/12 | 16:00 UK - Online Seminar🚨
"Cheater driven evolution of reproductive division of labour" by Dr. Nobuto Takeuchi. Please repost & to attend online please register to our 📧: lists.cam.ac.uk/sympa/subscr...
#biophysics #ecology #evolution
"Cheater driven evolution of reproductive division of labour" by Dr. Nobuto Takeuchi. Please repost & to attend online please register to our 📧: lists.cam.ac.uk/sympa/subscr...
#biophysics #ecology #evolution
November 28, 2024 at 3:51 PM
🚨Next week, Wed 04/12 | 16:00 UK - Online Seminar🚨
"Cheater driven evolution of reproductive division of labour" by Dr. Nobuto Takeuchi. Please repost & to attend online please register to our 📧: lists.cam.ac.uk/sympa/subscr...
#biophysics #ecology #evolution
"Cheater driven evolution of reproductive division of labour" by Dr. Nobuto Takeuchi. Please repost & to attend online please register to our 📧: lists.cam.ac.uk/sympa/subscr...
#biophysics #ecology #evolution
Reposted by Lakshmi Balasubramaniam
I am delighted to share our new preprint in which we reveal the crucial role for mechanical forces in myoblast fusion. Great work from Yoann, Sushil and Aleksandra and great collaboration with Christophe Marcelle and Amin Doostmohammadi!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 24, 2024 at 10:02 PM
I am delighted to share our new preprint in which we reveal the crucial role for mechanical forces in myoblast fusion. Great work from Yoann, Sushil and Aleksandra and great collaboration with Christophe Marcelle and Amin Doostmohammadi!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Lakshmi Balasubramaniam
🚨This week, Wed 20/11 | 16:00 UK - Online Seminar🚨
"Mechanics of basal body patterning during multiciliated cell morphogenesis" by Dr. Jakub Sedzinski. Please repost & to attend online sign up to our 📧: lists.cam.ac.uk/sympa/subscr...
#mechanobiology #DevBio #cellbiology 🐸🧫
"Mechanics of basal body patterning during multiciliated cell morphogenesis" by Dr. Jakub Sedzinski. Please repost & to attend online sign up to our 📧: lists.cam.ac.uk/sympa/subscr...
#mechanobiology #DevBio #cellbiology 🐸🧫
November 18, 2024 at 8:56 AM
🚨This week, Wed 20/11 | 16:00 UK - Online Seminar🚨
"Mechanics of basal body patterning during multiciliated cell morphogenesis" by Dr. Jakub Sedzinski. Please repost & to attend online sign up to our 📧: lists.cam.ac.uk/sympa/subscr...
#mechanobiology #DevBio #cellbiology 🐸🧫
"Mechanics of basal body patterning during multiciliated cell morphogenesis" by Dr. Jakub Sedzinski. Please repost & to attend online sign up to our 📧: lists.cam.ac.uk/sympa/subscr...
#mechanobiology #DevBio #cellbiology 🐸🧫
Reposted by Lakshmi Balasubramaniam
Postdoc position available in the Röper lab at the University of Cambridge @PDN_Cambridge!
Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids!
jobs.cam.ac.uk/job/48947/
Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids!
jobs.cam.ac.uk/job/48947/
November 14, 2024 at 12:59 AM
Postdoc position available in the Röper lab at the University of Cambridge @PDN_Cambridge!
Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids!
jobs.cam.ac.uk/job/48947/
Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids!
jobs.cam.ac.uk/job/48947/